WHO monographs on selected medicinal plants - travolekar.ru
WHO monographs on selected medicinal plants - travolekar.ru
WHO monographs on selected medicinal plants - travolekar.ru
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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />
glabrous or with a few scattered hairs; lobes obl<strong>on</strong>g, 1.5–2.5 mm, outside<br />
glabrous or slightly farinose-pubescent, margins sometimes ciliate. Stamens<br />
5. Ovary 2-celled. F<strong>ru</strong>iting head 14–18 mm in diameter, f<strong>ru</strong>it a dry<br />
capsule. The plant entwines other trees with its hooked thorns (6, 8, 9).<br />
Plant material of interest: dried hook-bearing stem branch<br />
General appearance<br />
Cylindrical or subsquare, 1–4 cm l<strong>on</strong>g, 2–5 mm in diameter. Externally<br />
reddish-brown to dark brown or yellow-brown with fine l<strong>on</strong>gitudinal<br />
striati<strong>on</strong>s, glabrous, or yellowish-green to greyish-brown, sometimes<br />
with white dotted lenticels, covered with yellowish-brown pubescence.<br />
Transverse secti<strong>on</strong>: square to elliptical. Most nodes of stem branches with<br />
two opposite downward curved hooks/prickles (sterile peduncles), some<br />
with a hook <strong>on</strong>ly <strong>on</strong> <strong>on</strong>e side and with raised scars <strong>on</strong> the other side;<br />
hooks relatively flattened or rounded, apex acute, base relatively broad;<br />
dotted scars of fallen petiole and ring-shaped stipule scars visible <strong>on</strong> the<br />
branch at the hook base; transverse secti<strong>on</strong> obl<strong>on</strong>g to elliptical. Texture<br />
hard and tenacious, fracture yellowish-brown, bark fibrous, pith yellowish-white<br />
to light brown or hollowed (1, 2).<br />
Organoleptic properties<br />
Odour: n<strong>on</strong>e; taste: slight (1, 2).<br />
Microscopic characteristics<br />
Transverse secti<strong>on</strong> of the prickle (hook) reveals vascular bundles in the<br />
cortex, unevenly distributed and arranged in a ring. Parenchyma cells in<br />
the sec<strong>on</strong>dary cortex c<strong>on</strong>taining crystals of calcium oxalate (2, 3).<br />
Powdered plant material<br />
To be established in accordance with nati<strong>on</strong>al requirements.<br />
General identity tests<br />
Macroscopic examinati<strong>on</strong> (1–3), microchemical test (1–3), and highperformance<br />
liquid chromatography for the presence of characteristic<br />
oxindole alkaloids (2, 10–13).<br />
Purity tests<br />
Microbiology<br />
Tests for specific microorganisms and microbial c<strong>on</strong>taminati<strong>on</strong> limits are<br />
as described in the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines for assessing quality of herbal medicines<br />
with reference to c<strong>on</strong>taminants and residues (14).<br />
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