WHO monographs on selected medicinal plants - travolekar.ru
WHO monographs on selected medicinal plants - travolekar.ru WHO monographs on selected medicinal plants - travolekar.ru
Folium Rosmarini 14. Cantrell CL et al. Seco-hinokiol, a new abietane diterpenoid from Rosmarinus officinalis. Journal of Natural Products, 2005, 68:98–100. 15. Hagers Handbuch der Drogen (CD ROM). Heidelberg, Springer Verlag, 2003 [in German]. 16. Sotelo-Félix JI et al. Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat. Journal of Ethnopharmacology, 2002, 81:145–154. 17. Fahim FA et al. Allied studies on the effect of Rosmarinus officinalis L. on experimental hepatotoxicity and mutagenesis. International Journal of Food Sciences and Nutrition, 1999, 50:413–427. 18. Lo AH et al. Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-B in mouse macrophages. Carcinogenesis, 2002, 23:983–991. 19. Aruoma OI et al. Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid. Xenobiotica, 1992, 22:257–268. 20. Fuhrman B et al. Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic. Antioxidant and Redox Signaling, 2000, 2:491–506. 21. Gutiérrez ME et al. Interaction of tocopherols and phenolic compounds with membrane lipid components: Evaluation of their antioxidant activity in a liposomal model system. Life Science, 2003, 72:2337–2360. 22. Del Baño MJ et al. Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis: antioxidant activity. Journal of Agricultural and Food Chemistry, 2003, 51:4247–4253. 23. Zeng HH et al. Antioxidant properties of phenolic diterpenes from Rosmarinus officinalis. Acta Pharmacologia Sinica, 2001, 22:1094–1098. 24. Asai A, Nakagawa K, Miyazawa T. Antioxidative effects of turmeric, rosemary and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice. Bioscience, Biotechnology and Biochemistry, 1999, 63:2118–2122. 25. Calabrese V et al. Biochemical studies of a natural antioxidant isolated from rosemary and its application in cosmetic dermatology. International Journal of Tissue Reactions, 2000, 22:5–13. 26. Slameňová D et al. Rosemary-stimulated reduction of DNA strand breaks and FPG-sensitive sites in mammalian cells treated with H 2 O 2 or visible light-excited methylene blue. Cancer Letters, 2002, 177:145–153. 27. Del Campo J, Amiot MJ, Nguyen-TC. Antimicrobial effect of rosemary extracts. Journal of Food Protection, 2000, 63:1359–1368. 28. Bagamboula CF, Uyttendaele M, Debevere J. Antimicrobial effect of spices and herbs on Shigella sonnei and Shigella flexneri. Journal of Food Protection, 2003, 66:668–673. 29. Makino T et al. Suppressive effects of rosmarinic acid on mesangioproliferative glomerulonephritis in rats. Nephron, 2002, 92:898–904. 307
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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />
Dosage forms<br />
C<strong>ru</strong>de d<strong>ru</strong>g for infusi<strong>on</strong>s, dry extracts, fluidextract and other Galenical<br />
preparati<strong>on</strong>s for internal and external use (47).<br />
Posology<br />
(Unless otherwise specified)<br />
Daily dosage: for oral use 4–6 g of herb. Infusi<strong>on</strong>: 2–4 g in 150 ml water<br />
three times daily. Fluidextract (1:1, 45% ethanol w/w) 1.5–3.0 ml daily.<br />
Tincture (1:5, 70% ethanol) 3–8.5 ml daily. Dry extract (4.5–5.5:1 w/w)<br />
0.36–0.44 g, three times daily. External use: boil 50 g of herb in 1 l of water,<br />
add to <strong>on</strong>e full bath (47).<br />
References<br />
1. European Pharmacopoeia, 5th ed. Strasbourg, Directorate for the Quality of<br />
Medicines of the Council of Europe (EDQM), 2005.<br />
2. Bedevian AK. Illustrated polyglottic dicti<strong>on</strong>ary of plant names. Cairo, Medbouly<br />
Library, 1994.<br />
3. Farnsworth NR, ed. NAPRALERT database. Chicago, University of Illinois<br />
at Chicago, IL (an <strong>on</strong>line database available directly through the University<br />
of Illinois at Chicago or through the Scientific and Technical Network [STN]<br />
of Chemical Abstracts Services), 30 June 2005.<br />
4. Youngken HW. Textbook of pharmacognosy, 6th ed. Philadelphia, PA, Blakist<strong>on</strong>,<br />
1950.<br />
5. Bisset NR, Wichtl M, eds. Herbal d<strong>ru</strong>gs and phytopharmaceuticals, English<br />
ed. Boca Rat<strong>on</strong>, FL, Medpharm, 1994.<br />
6. Perry LM, Metzger J. Medicinal <strong>plants</strong> of east and southeast Asia: Attributed<br />
properties and uses. Cambridge, MA, MIT Press, 1980.<br />
7. B<strong>ru</strong>net<strong>on</strong> J. Pharmacognosy, phytochemistry, <strong>medicinal</strong> <strong>plants</strong>. Paris, Lavoisier,<br />
1995.<br />
8. Boulos L. Medicinal <strong>plants</strong> of North Africa. Alg<strong>on</strong>ac, Michigan, Reference<br />
Publicati<strong>on</strong>s, 1983.<br />
9. British herbal pharmacopoeia. Exeter, British Herbal Medicine Associati<strong>on</strong>,<br />
1996.<br />
10. Ziaková A, Brandsteterová E. Validati<strong>on</strong> of HPLC determinati<strong>on</strong> of phenolic<br />
acids present in some Lamiaceae family <strong>plants</strong>. Journal of Liquid Chromatography<br />
and Related Technologies, 2003, 26:443–453.<br />
11. <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines for assessing quality of herbal medicines with reference to<br />
c<strong>on</strong>taminants and residues. Geneva, World Health Organizati<strong>on</strong>, 2007.<br />
12. Guidelines for predicting dietary intake of pesticide residues, 2nd rev. ed. Geneva,<br />
World Health Organizati<strong>on</strong>, 1997 (<str<strong>on</strong>g>WHO</str<strong>on</strong>g>/FSF/FOS/97.7).<br />
13. Blumenthal M et al., eds. The complete German Commissi<strong>on</strong> E <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g>:<br />
Therapeutic guide to herbal medicines. Austin, TX, American Botanical<br />
Council, 1998.<br />
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