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WHO monographs on selected medicinal plants - travolekar.ru

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Oleum Ricini<br />

Acid-insoluble ash<br />

Not applicable.<br />

Water-soluble extractive<br />

Not applicable.<br />

Water<br />

Not more than 0.3% according to the method of Karl-Fischer (1).<br />

Pesticide residues<br />

The recommended maximum limit of aldrin and dieldrin is not more than<br />

0.05 mg/kg (1). For other pesticides, see the European pharmacopoeia (1)<br />

and the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> quality c<strong>on</strong>trol methods for <strong>medicinal</strong> plant materials (18)<br />

and pesticide residues (19).<br />

Heavy metals<br />

For maximum limits and analysis of heavy metals, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g><br />

guidelines for assessing quality of herbal medicines with reference to c<strong>on</strong>taminants<br />

and residues (18).<br />

Radioactive residues<br />

Where applicable, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines for assessing quality of<br />

herbal medicines with reference to c<strong>on</strong>taminants and residues (18).<br />

Other purity tests<br />

Specific gravity d 25 : 0.953–0.965 (1, 3, 4).<br />

25<br />

Sap<strong>on</strong>ificati<strong>on</strong> value: 176–187 (3–5).<br />

Acid value: not more than 1.5 (3, 4).<br />

Hydroxyl value: 155–177 (3, 4).<br />

Iodine value: 80–90 (1, 3).<br />

Peroxide value: not less than 150 (1).<br />

Optical rotati<strong>on</strong>: +3.5 to +6.0 (1).<br />

Refractive index: 1.478–1.480 (5).<br />

Chemical assays<br />

Fatty acid c<strong>on</strong>tent: palmitic (2% maximum), stearic (2.5% maximum),<br />

oleic and isomers (2.5–6.0%), linoleic (2.5–7.0%), linolenic (2.5% maximum),<br />

eicosenoic (1.0% maximum), ricinoleic acid (85–92%) and other<br />

fatty acids (maximum) determined by gas chromatography (1).<br />

273

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