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WHO monographs on selected medicinal plants - travolekar.ru

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />

Descripti<strong>on</strong><br />

The castor-oil plant is either cultivated or is found growing wild in most<br />

tropical and warm temperate countries. It varies from an annual, m<strong>on</strong>oecious<br />

herb in temperate regi<strong>on</strong>s to a tree attaining a height of 15 m in some<br />

tropical areas. There are hundreds of forms of the plant which vary in size,<br />

colour of stem and leaves, leaf markings, branching, size, colour and markings<br />

of seeds. Shoots and panicles glaucous. Leaves are large, alternate,<br />

petiolate, peltate, palmate, 5–12 lobed, the lobes serrate or dentate, green or<br />

reddish. The inflorescence is a raceme of staminate and pistillate flowers,<br />

often 30–60 cm high, the pistillate flowers occurring above the staminate<br />

<strong>on</strong>es <strong>on</strong> the floral axis. The f<strong>ru</strong>it is a 3-celled capsule generally covered with<br />

soft spines and dehiscing into 3 cocci, each c<strong>on</strong>taining an ovoid albuminous<br />

seed. Seeds obl<strong>on</strong>g, smooth, mottled and pois<strong>on</strong>ous (8, 12).<br />

Plant material of interest: fixed oil<br />

General appearance<br />

A colourless or pale yellow, clear, viscous oil, miscible with dehydrated<br />

ethanol or ether. It is <strong>on</strong>ly partly soluble in hexane (a distincti<strong>on</strong> from<br />

most other fixed oils). When cooled to 0 °C, it becomes more viscous, and<br />

turbidity is gradually formed (1–5).<br />

Organoleptic properties<br />

Odour: slight, characteristic; taste: initially bland, with a slightly acrid<br />

aftertaste (3, 4).<br />

General identity tests<br />

Physicochemical properties (2–4), chemical tests (3, 4), and gas chromatography<br />

analysis of fatty acids (1).<br />

Purity tests<br />

Microbiological<br />

Tests for specific microorganisms and microbial c<strong>on</strong>taminati<strong>on</strong> limits are<br />

as described in the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines for assessing quality of herbal medicines<br />

with reference to c<strong>on</strong>taminants and residues (18).<br />

Foreign organic matter<br />

To be established according to nati<strong>on</strong>al requirements.<br />

Total ash<br />

Not applicable.<br />

272

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