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WHO monographs on selected medicinal plants - travolekar.ru

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />

shows 1-layered epidermis, some epidermal cells el<strong>on</strong>gate forming unicellular<br />

hairs. Hypodermis single-layered. Cortex 8–14 layered, c<strong>on</strong>sisting<br />

of oval to polyg<strong>on</strong>al, thick-walled parenchymatous cells. Primary stele,<br />

tetrarch to heptarch, enclosed by a single-layered pericycle and singlelayered<br />

thick-walled cells of endodermis. Mature roots show 4–15 layers<br />

of cork, 1–2 layers of cork cambium. Vessels vary in size and shape, some<br />

cylindrical with tail-like, tapering ends; some d<strong>ru</strong>m shaped with perforati<strong>on</strong><br />

<strong>on</strong> end walls or lateral walls. Tracheids cylindrical with tapering<br />

pointed ends (1).<br />

Powdered plant material<br />

Dusty grey in colour. Groups of cork cell fragments, thick-walled parenchyma,<br />

pitted vessels and aseptate fibres. Simple round to oval starch<br />

grains, 25–105 μm in diameter (1).<br />

General identity tests<br />

Macroscopic and microscopic examinati<strong>on</strong>s, microchemical tests and<br />

thin-layer chromatography (1, 2), and high-performance liquid chromatography–mass<br />

spectrometry (11).<br />

Purity tests<br />

Microbiological<br />

Tests for specific microorganisms and microbial c<strong>on</strong>taminati<strong>on</strong> limits are<br />

as described in the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines for assessing quality of herbal medicines<br />

with reference to c<strong>on</strong>taminants and residues (12).<br />

Foreign organic matter<br />

Not more than 2% (1).<br />

Total ash<br />

Not more than 7% (1, 2).<br />

Acid-insoluble ash<br />

Not more than 3% (2).<br />

Water-soluble extractive<br />

Not less than 20% (1).<br />

Alcohol-soluble extractive<br />

Not less than 30% (2).<br />

Loss <strong>on</strong> drying<br />

C<strong>on</strong>tains not more than 13% water (2).<br />

260

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