WHO monographs on selected medicinal plants - travolekar.ru

<strong>WHO</strong> <strong>monographs</strong> on selected medicinal plants
Adverse reactions
No information was found.
Contraindications
No information was found.
Warnings
If diarrhoea persists for more than 3–4 days, or is associated with abdominal
pain or rectal bleeding, consult a health care professional.
Precautions
Drug interactions
In one ex vivo study, oral administration of an extract of the fruit containing
anthocyanins inhibited platelet aggregation when given at doses of
480 mg daily for 30–60 days (45).
Therefore, fruit extracts have antiplatelet aggregating properties
and very high doses should be used cautiously in patients with haemorrhagic
disorders and those taking anticoagulant or antiplatelet
drugs.
Carcinogenesis, mutagenesis, impairment of fertility
No mutagenicity or carcinogenicity has been reported.
Pregnancy: teratogenic effects
No teratogenic effects were observed in animals treated with 3–5 times
the human dose (2).
Other precautions
No information was found.
Dosage forms
Crude drug, extracts, tablets and capsules.
Posology
(Unless otherwise indicated)
Internal: daily dosage of crude drug 20–60 g (2). Extracts: 80–160 mg of
extract standardized to 25% anthocyanosides (three times daily). The
dose of anthocyanosides is 20–40 mg three times daily (20). External: 10%
decoction; equivalent preparations (20).
222