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WHO monographs on selected medicinal plants - travolekar.ru

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />

Foreign organic matter<br />

Not more than 5% (3).<br />

Total ash<br />

Not more than 3% (3).<br />

Acid-insoluble ash<br />

Not more than 1.5% (3).<br />

Water-soluble extractive<br />

To be established in accordance with nati<strong>on</strong>al requirements.<br />

Loss <strong>on</strong> drying<br />

Not more than 12% (10).<br />

Swelling value<br />

Not less than 4.5 determined <strong>on</strong> the powdered d<strong>ru</strong>g (1).<br />

Pesticide residues<br />

The recommended maximum limit of aldrin and dieldrin is not more than<br />

0.05 mg/kg (1). For other pesticides, see the European pharmacopoeia (1)<br />

and the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines <strong>on</strong> assessing quality of herbal medicines with<br />

reference to c<strong>on</strong>taminants and residues (9) and pesticide residues (11).<br />

Heavy metals<br />

For maximum limits and analysis of heavy metals, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g><br />

guidelines <strong>on</strong> assessing quality of herbal medicines with reference to c<strong>on</strong>taminants<br />

and residues (9).<br />

Radioactive residues<br />

Where applicable, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines <strong>on</strong> assessing quality of<br />

herbal medicines with reference to c<strong>on</strong>taminants and residues (9).<br />

Chemical assays<br />

To be established in accordance with nati<strong>on</strong>al requirements.<br />

Major chemical c<strong>on</strong>stituents<br />

C<strong>on</strong>tains water-soluble polysaccharides (50%), primarily lichenin, a linear<br />

cellulose-like polymer of -D-glucose units, and isolichenin, an -Dglucose<br />

polymer. Two glucans, lichenan and isolichenan, have been isolated<br />

from the lichen Cetraria islandica (12), as well as galactomannans<br />

(5). Major sec<strong>on</strong>dary metabolites include the lichen acids (depsid<strong>on</strong>es),<br />

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