WHO monographs on selected medicinal plants - travolekar.ru

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General technical notices medicinal plant part, the relevant section of each monograph may still include these. Geographical distribution is not normally found in official compendia, but is included here to provide additional quality assurance information. The detailed botanical description under Description is intended for quality assurance at the stages of production and collection; the description of the crude drug material under Plant material of interest is for the same purpose at the manufacturing and commerce stages. General identity tests, Purity tests and Chemical assays are all normal compendial components included under those headings in these <strong>monographs</strong>. Where purity tests do not specify accepted limits, those limits should be set in accordance with national requirements by the appropriate authorities of Member States. Each medicinal plant and the specific plant part used as crude drug material contains active or major chemical constituents with a characteristic profile that can be used for chemical quality control and quality assurance. These constituents are described in the Major chemical constituents. Descriptions included in Medicinal uses should not be taken as implying <strong>WHO</strong>’s official endorsement or approval for such uses. They merely represent the systematic collection of scientific information available at the time of preparation, for information exchange. The first category, Uses supported by clinical data, includes medical indications that are well established in some countries and have been validated by clinical studies documented in the scientific literature. Clinical trials may be controlled, randomized, double-blind studies, open trials, cohort studies or well documented observations on therapeutic applications. The second category, Uses described in pharmacopoeias and well established documents, includes medicinal uses that are well established in many countries and are included in official pharmacopoeias or governmental <strong>monographs</strong>. Uses having a pharmacologically plausible basis are also included, as well as information resulting from clinical studies that clearly need to be repeated because of conflicting results. The third category, Uses described in traditional medicine, refers to indications described in unofficial pharmacopoeias and other literature, and to traditional uses. Their appropriateness could not be assessed, because sufficient data to support the claims could not be found in the literature. Traditional uses that address severe pathologies, such as cancer, AIDS, hepatitis, etc., as they relate to these modern biomedical terms, should only be included under the third heading if pharmacological data or robust ethnopharmacological/ethnobotanical reports are available to support the claims. 6
General technical notices The Experimental pharmacology section includes only the results of investigations that prove or disprove the cited medicinal uses. Abbreviated details of the best-performed studies have been included in this section. Other published experimental data that are not associated with the medicinal uses have not been included, to avoid confusion. The details included in the References have been checked against the original sources wherever possible. For references in languages other than English, except for those in Chinese, Japanese and Korean, the title is given in the original language, except in cases where an English summary is available. 7
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