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WHO monographs on selected medicinal plants - travolekar.ru

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />

Radioactive residues<br />

Where applicable, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines <strong>on</strong> assessing quality of<br />

herbal medicines with reference to c<strong>on</strong>taminants and residues (13).<br />

Chemical assays<br />

Total tannins not less than 10% (1).<br />

Major chemical c<strong>on</strong>stituents<br />

The major c<strong>on</strong>stituents are hydrolysable ellagitannins (up to 28%) and<br />

other polyphenols (3, 12, 16, 17). St<strong>ru</strong>ctures of ellagic acid and punicalin<br />

are presented below.<br />

Ellagic acid<br />

O<br />

HO<br />

OH<br />

Punicalin<br />

HO<br />

HO<br />

O<br />

O<br />

O<br />

OH<br />

OH<br />

HO<br />

HO<br />

O<br />

HO<br />

O<br />

O<br />

OH<br />

OH<br />

O<br />

O<br />

O<br />

O<br />

OH<br />

O<br />

HO<br />

O<br />

HO<br />

OH<br />

HO<br />

OH<br />

Medicinal uses<br />

Uses supported by clinical data<br />

N<strong>on</strong>e.<br />

Uses described in pharmacopoeias and well established documents<br />

Orally for the treatment of chr<strong>on</strong>ic diarrhoea, dysentery, gingivitis and<br />

intestinal parasites (1, 7, 18).<br />

Uses described in traditi<strong>on</strong>al medicine<br />

Treatment of br<strong>on</strong>chitis, fever, gastrointestinal ailments, menorrhagia,<br />

respiratory tract infecti<strong>on</strong>s, skin rashes, vaginal infecti<strong>on</strong>s and worms<br />

(12, 19).<br />

120

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