WHO monographs on selected medicinal plants - travolekar.ru

Introduction
changes. For easy reference, two cumulative indexes are provided as annexes.
Annex 2 lists the <strong>monographs</strong> in alphabetical order of the plant
name, while Annex 3 is arranged according to the plant materials of interest.
For the convenience of readers, an additional cumulative list of
plant names (scientific name followed by family name) which appeared
under the heading “definition” in each monograph, has been added (Annex
4). In response to the recommendation of the Ottawa Consultation
in 2001, a cumulative index of major chemical constituents arranged in
alphabetical order (Annex 5), a cumulative index ordered by Chemical
Abstracts Service (CAS) number (Annex 6) and a cumulative index ordered
by molecular formula (Annex 7) have also been included in this
volume.
Under the heading “Geographical distribution”, an attempt has been
made to describe the geographical distribution of the plant, i.e. its natural
distribution, where it is cultivated, and conditions of cultivation, harvesting
and storage. This has been a challenge, owing to the lack of data based
on established national good agricultural practices and/or good collection
practices (GACP) for medicinal plants. In 2007, <strong>WHO</strong> published the
<strong>WHO</strong> guidelines on good manufacturing practices (GMP) for herbal medicines,
which provide general technical guidance on obtaining medicinal
plant materials of good quality for the production of herbal medicines in
the overall context of quality assurance and control of herbal medicines.
<strong>WHO</strong> also compiled new guidelines on assessing quality for safety of
herbal medicines with reference to contaminants and residues which were
published in 2007. It is hoped that these guidelines will facilitate the implementation
of GMP for herbal medicines at the national level, and the
development of national quality standards/specifications for herbal medicines,
which in turn should bridge the current information gap in this
area.
At the consultation, the following technical issues were pointed out
for consideration during the preparation of the <strong>monographs</strong>:
Specify extract according to original literature, whenever possible.
Posology: as a general rule make clear that a given posology has
been found either in the report of clinical trials or referring to traditional
indications. These guidelines have been followed in the
preparation of this volume wherever possible.
Provide posologies as they relate to the specific indications –
the dosage forms have to be consistent with their respective
indications.
Specific posologies should be indicated for specific uses and dosage
forms whenever available.
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