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WHO monographs on selected medicinal plants - travolekar.ru

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> <str<strong>on</strong>g>m<strong>on</strong>ographs</str<strong>on</strong>g> <strong>on</strong> <strong>selected</strong> <strong>medicinal</strong> <strong>plants</strong><br />

Powdered plant material<br />

Greyish-green to brown powder with faint odour; fragments of the lamina<br />

with more or less sinuous walls and anomocytic stomata; covering<br />

trichomes, scattered or in felted masses and large, glandular trichomes<br />

with brown c<strong>on</strong>tents; groups of lignified fibres and vessels from the midrib<br />

and petiole, the larger vessels with reticulate thickening (1, 2).<br />

General identity tests<br />

Macroscopic and microscopic examinati<strong>on</strong>s (1, 2, 17), and thin-layer<br />

chromatography (1, 2).<br />

Purity tests<br />

Microbiological<br />

Tests for specific microorganisms and microbial c<strong>on</strong>taminati<strong>on</strong> limits are<br />

as described in the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines <strong>on</strong> assessing quality of herbal medicines<br />

with reference to c<strong>on</strong>taminants and residues (18).<br />

Foreign organic matter<br />

Not more than 2.0% (1, 2).<br />

Total ash<br />

Not more than 15.0% (1, 2).<br />

Acid-insoluble ash<br />

Not more than 4% (2).<br />

Water-soluble extractive<br />

Not less than 25.0% (2).<br />

Loss <strong>on</strong> drying<br />

Not more than 8% (1).<br />

Pesticide residues<br />

The recommended maximum limit of aldrin and dieldrin is not more than<br />

0.05 mg/kg (19). For other pesticides, see the European pharmacopoeia (19)<br />

and the <str<strong>on</strong>g>WHO</str<strong>on</strong>g> guidelines <strong>on</strong> assessing quality of herbal medicines with<br />

reference to c<strong>on</strong>taminants and residues (18) and pesticide residues (20).<br />

Heavy metals<br />

For maximum limits and analysis of heavy metals, c<strong>on</strong>sult the <str<strong>on</strong>g>WHO</str<strong>on</strong>g><br />

guidelines <strong>on</strong> assessing quality of herbal medicines with reference to c<strong>on</strong>taminants<br />

and residues (18).<br />

94

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