full issue - Association of Biotechnology and Pharmacy
full issue - Association of Biotechnology and Pharmacy
full issue - Association of Biotechnology and Pharmacy
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Current Trends in <strong>Biotechnology</strong> <strong>and</strong> <strong>Pharmacy</strong><br />
Vol. 5 (3) 1362-1371 July 2011, ISSN 0973-8916 (Print), 2230-7303 (Online)<br />
1366<br />
Nitric oxide radical scavenging activity:<br />
Scavenging <strong>of</strong> nitric oxide by various extracts<br />
was found to be concentration dependent.<br />
Maximum inhibition <strong>of</strong> nitric oxide formation<br />
was produced by alcoholic extract <strong>and</strong> had IC<br />
50<br />
<strong>of</strong> 495.30±3.09 as against 415.14± 5.98 for BHA<br />
(Fig. 1; Table-2).<br />
Total reducing power: From 100 µg/ml,<br />
chlor<strong>of</strong>orm <strong>and</strong> ethanol extracts <strong>and</strong> st<strong>and</strong>ardascorbic<br />
acid <strong>and</strong> BHA showed reductive<br />
capabilities. At 500 µg/ ml, the reducing power<br />
<strong>of</strong> st<strong>and</strong>ards <strong>and</strong> extracts showed the following<br />
order: BHA > ethanol extract > Ascorbic acid ><br />
chlor<strong>of</strong>orm. Reducing power <strong>of</strong> ethanol <strong>and</strong><br />
chlor<strong>of</strong>orm extracts at 500µg/ml was comparable<br />
(P < 0.05) to that <strong>of</strong> ascorbic acid (Table-1).<br />
Superoxide anion radical scavenging activity:<br />
Superoxide anion radical generation was<br />
Table 2. Total reducing power, nitric oxide <strong>and</strong> super oxide scavenging activity <strong>of</strong> different<br />
concentrations <strong>of</strong> AA.BHA.XSCA,XSAE<br />
In-vitro antioxidant <strong>and</strong> antilipidemic activities <strong>of</strong> Xanthium strumarium L.