April Journal-2009.p65 - Association of Biotechnology and Pharmacy
April Journal-2009.p65 - Association of Biotechnology and Pharmacy
April Journal-2009.p65 - Association of Biotechnology and Pharmacy
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Current Trends in <strong>Biotechnology</strong> <strong>and</strong> <strong>Pharmacy</strong><br />
Vol. 3 (2) 138-148, <strong>April</strong> 2009. ISSN 0973-8916<br />
146<br />
Government <strong>of</strong> India, India, <strong>and</strong> Department <strong>of</strong><br />
Atomic Energy (BNRS), for financial support to<br />
perform this work. We thank Dr. H.N. Yejurvedi,<br />
In-charge, animal facility, Department <strong>of</strong> Zoology,<br />
University <strong>of</strong> Mysore for providing animals for<br />
the experiment.<br />
References<br />
1. Srinivasan, S., Ranga, R.S., Burikihanov, R.,<br />
Han, S.S. <strong>and</strong> Chendil, D. (2007). Par-4-<br />
Dependent Apoptosis by the Dietary<br />
Compound Withaferin A in Prostate Cancer<br />
Cells. Cancer Research, 67: 246-53.<br />
2. Malik, F., Kumar, A., Bhushan, S., Khan,<br />
S., Bhatia, A., Suri, K.A., Qazi, G.N. <strong>and</strong><br />
Singh, J. (2007). Reactive oxygen species<br />
generation <strong>and</strong> mitochondrial dysfunction in<br />
the apoptotic cell death <strong>of</strong> human myeloid<br />
leukemia HL-60 cells by a dietary compound<br />
withaferin A with concomitant protection by<br />
N-acetyl cysteine. Apoptosis, 12:2115-2133.<br />
3. Sen, N., Banerjee, B., Das, B.B., Ganguly,<br />
A., Sen, T., Pramanik, S., Mukhopadhyay,<br />
S. <strong>and</strong> Majumder, H.K. (2007). Apoptosis<br />
is induced in leishmanial cells by a novel<br />
protein kinase inhibitor withaferin A <strong>and</strong> is<br />
facilitated by apoptotic topoisomerase I-<br />
DNA complex. Cell Death <strong>and</strong><br />
Differentiation, 14: 358-367.<br />
4. Mohan, R., Hammers, H.J., Mohan, P.B.,<br />
Zhan, X.H., Herbstritt, C.J., Ruiz, A., Zhang,<br />
L., Hanson, A.D., Conner, B.P., Rougas, J.<br />
<strong>and</strong> Pribluda, V.S. (2004). Withaferin A is<br />
a potent inhibitor <strong>of</strong> angiogenesis.<br />
Angiogenesis, 7: 115-122.<br />
5. Liotta, L.A., Steeg, P.S. <strong>and</strong> Stetler-<br />
Stevenson, W.G. (1991). Cancer metastasis<br />
<strong>and</strong> angiogenesis: an imbalance <strong>of</strong> positive<br />
<strong>and</strong> negative regulation. Cell, 64: 327-336.<br />
6. Bhattacharya, S.K., Satyan, K.S. <strong>and</strong><br />
Ghosal, S. (1997). Antioxidant activity <strong>of</strong><br />
glycowithanolides from W somnifera in rat<br />
Sp1 transcription factor<br />
brain frontal cortex <strong>and</strong> striatum. Indian<br />
<strong>Journal</strong> <strong>of</strong> Experimental Biology, 35: 236-<br />
239.<br />
7. Bhattacharya, A., Ghosal, S. <strong>and</strong><br />
Bhattacharya, S.K. (2001). Anti-oxidant<br />
effect <strong>of</strong> Withania somnifera<br />
glycowithanolides in chronic footshock<br />
stress-induced perturbations <strong>of</strong> oxidative<br />
free radical scavenging enzymes <strong>and</strong> lipid<br />
peroxidation in rat frontal cortex <strong>and</strong><br />
striatum. <strong>Journal</strong> <strong>of</strong> Ethnopharmacology, 74:<br />
1-6.<br />
8. Mishra, L.C., Singh, B.B. <strong>and</strong> Dagenais, S.<br />
(2000). Scientific basis for the therapeutic<br />
use <strong>of</strong> Withania somnifera (Ashwag<strong>and</strong>ha):<br />
a review. Alternative Medicine Review, 5:<br />
334-346.<br />
9. Upton, R. (2000). American Herbal<br />
Pharmacopoeia <strong>and</strong> Therapeutic<br />
Compendium: Ashwag<strong>and</strong>ha Root<br />
(Withania somnifera) - St<strong>and</strong>ards <strong>of</strong><br />
Analysis, Quality Control, <strong>and</strong> Therapeutics.<br />
Santa Cruz, California.<br />
10. Forsythe, J.A., Jiang, B.H., Iyer, N.V.,<br />
Agani, F., Leung, S.W., Koos, R.D. <strong>and</strong><br />
Semenza, G.L. (1996). Activation <strong>of</strong> vascular<br />
endothelial growth factor gene transcription<br />
by hypoxia-inducible factor 1. Molecular<br />
<strong>and</strong> Cellular Biology, 16: 4604-4613.<br />
11. Feldser, D., Agani, F., Iyer, N.V., Pak, B.,<br />
Ferreira, G. <strong>and</strong> Semenza, G.L. (1999).<br />
Reciprocal positive regulation <strong>of</strong> hypoxiainducible<br />
factor 1alpha <strong>and</strong> insulin-like<br />
growth factor 2. Cancer Research, 59: 3915-<br />
3918.<br />
12. Tischer, E., Mitchell, R., Hartman, T., Silva,<br />
M., Gospodarowicz, D., Fiddes, J.C. <strong>and</strong><br />
Abraham, J.A. (1991). The human gene for<br />
vascular endothelial growth factor. Multiple<br />
protein forms are encoded through<br />
alternative exon splicing. <strong>Journal</strong> <strong>of</strong><br />
Biological Chemistry, 266: 11947-11954.