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SAN FRANCISCOMEDICINE - California Society of Addiction ...

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<strong>Addiction</strong> and Recovery<br />

Lessons in Urban Survival<br />

A Hustler Tells All<br />

Eisha Zaid<br />

“<br />

You can tell a lot by a person’s shoes.<br />

One look tells me if they are worth<br />

my efforts,” he said.<br />

My patient, a forty-something gentleman,<br />

was educating me about what he<br />

called “urban survival.”<br />

As a native <strong>of</strong> the Tenderloin, he relied<br />

on certain tactics to make ends meet. He<br />

was an expert-level street hustler. He was<br />

one <strong>of</strong> the successful ones and was capable<br />

<strong>of</strong> making a small fortune, probably<br />

enough to pay rent and live comfortably<br />

in a nice apartment somewhere outside<br />

the Tenderloin.<br />

Sadly, he burned through his earnings,<br />

spending massive amounts on one<br />

thing—crack cocaine.<br />

“Sometimes it feels like I am drowning<br />

just thinking about how much money<br />

I owe. But I want it [crack]. I need it. And I<br />

have to get it.”<br />

*****<br />

Cocaine is derived from the leaves <strong>of</strong><br />

Erythroxylon coca, a plant endemic to the<br />

Andes. In historical records, cocaine chewing<br />

was documented in South America<br />

as far back as 4,000 years ago, and for<br />

the last hundred years the plant has had<br />

medicinal uses because <strong>of</strong> its vasoconstricting<br />

effects. 1,2 Cocaine has multiple<br />

actions, including that <strong>of</strong> local anesthetic,<br />

CNS stimulant, appetite depressant, and<br />

vasoconstrictor. The effects are largely<br />

mediated through the inhibition <strong>of</strong> norepinephrine,<br />

dopamine, and serotonin<br />

uptake. 3<br />

Cocaine has become a popular street<br />

drug that can be sniffed, smoked, or injected<br />

intraveneously. As a recreational<br />

agent, cocaine has variable purity. The<br />

purest forms are white powder, while less<br />

pure forms are more yellow and have been<br />

cut with other drugs, such as lidocaine, caffeine,<br />

methamphetamine, ephedrine, and<br />

phencyclidine. 3 When cocaine is heated<br />

in an alkaline solution, it transforms into<br />

“crack,” which is sold in 100–150 mg<br />

“rocks” that can be smoked, while a “line”<br />

weighs 20–30 mg and is snorted. 3<br />

*****<br />

When I first met him, he was completely<br />

suicidal and was brought into the<br />

SFGH Psychiatric Emergency Services after<br />

being placed on a 5150 hold for being a<br />

danger to himself. After the initial evaluation,<br />

he was transferred to the inpatient<br />

psychiatric unit. At the time, he had no<br />

home and was completely out <strong>of</strong> money.<br />

He was a tall, thin, middle-aged man<br />

with a pinkish complexion. His hair was<br />

combed and slicked back. He wore a lime<br />

green collar shirt over blue hospital gown<br />

pants. His two front teeth protruded outward<br />

and had been eaten away and were<br />

stained brown.<br />

During our first meeting, it was as<br />

though everything was in slow motion.<br />

He moved aimlessly and spoke slowly<br />

when recounting the details <strong>of</strong> his suicide<br />

attempt. He had a flat affect, showing little<br />

facial expression. He appeared remorseful<br />

but remained deeply depressed. At<br />

times he would become teary-eyed when<br />

talking about being abused as a child and<br />

about his life in the Tenderloin. He was<br />

diagnosed with bipolar and polysubstance<br />

dependence.<br />

“When I get low, I get really low and go<br />

into these dark bouts <strong>of</strong> depression. There<br />

is no reason to live for me. No one gives a<br />

shit about me,” he said.<br />

His past addiction was alcohol; his<br />

current substance was cocaine. His heavy<br />

drug use required excessive amounts <strong>of</strong><br />

money, which he <strong>of</strong>ten did not have. Thus<br />

he borrowed from street lenders and still<br />

had to pay back his debt.<br />

The chronic use had left his life in<br />

shambles. He went from having it all—a<br />

condo, a girlfriend, and a stable job—to<br />

having nothing. He was living on the<br />

streets, had made many enemies, and<br />

relied on hustling to get his daily fix.<br />

He had been admitted to our inpatient<br />

unit numerous times before for suicide<br />

attempts and was in and out <strong>of</strong> residential<br />

treatment programs. He was followed by<br />

a case manager and was plugged into an<br />

extensive network <strong>of</strong> social support services,<br />

but he had difficulty committing to<br />

appointments and taking his medications.<br />

The hospital had become his security net,<br />

a revolving door for him.<br />

*****<br />

<strong>Addiction</strong> to drugs results from alterations<br />

in neurochemical processes, which<br />

ultimately lead to increased drug-seeking<br />

behavior. Cocaine, like many other drugs <strong>of</strong><br />

abuse, is highly addictive because it blocks<br />

dopamine uptake and results in increased<br />

dopamine levels in the nucleus accumbens.<br />

4 With respect to behavior, dopamine<br />

promotes reward-seeking behavior. 5<br />

Interestingly, with increased cocaine<br />

use, dopamine release results from exposure<br />

to certain stimuli, such as drug<br />

paraphernalia or environmental cues,<br />

findings that have been demonstrated in<br />

animal models. 6 This conditioned response<br />

explains the drug-seeking behavior observed<br />

in chronic users, who are driven<br />

to do whatever it takes to get their neurochemical<br />

fix.<br />

*****<br />

Over his two-week hospitalization, I<br />

Continued on the following page . . .<br />

www.sfms.org June 2010 San Francisco Medicine 33

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