guidebook. - Fanconi Anemia Research Fund

366 Fanconi Anemia: Guidelines for Diagnosis and Management
Spina bifida: A birth defect in which the backbone
and spinal canal do not close before birth. Spina bifida
includes any birth defect involving insufficient closure
of the spine. 5
Sprengel: A condition in which the shoulder blade on
one or both sides is underdeveloped and abnormally
high. 1
SQ infusions: Acronym for subcutaneous infusions.
Stenosis: A narrowing or constriction of the diameter of
a bodily passage or orifice. 1
Stroma: The supporting tissue of the bone marrow.
This tissue provides the growth environment for blood
cells. 2
Surveillance, Epidemiology and End Results Program
(SEER): A premier source for cancer statistics
in the United States; sponsored by the National Cancer
Institute, NIH. SEER collects information on incidence,
survival, and prevalence from specific geographic areas
representing 26 percent of the country’s population and
compiles reports on all of these, plus cancer mortality
for the entire U.S. 8
Syndactyly: A union of two or more fingers or toes that
occurs in humans, often as a hereditary disorder marked
by the joining or webbing of two or more fingers or
toes. 1
T-cells: Lymphocytes responsible for “cell-mediated”
immune reactions; critical for immune resistance to
viruses, fungi, parasites and certain bacteria; important
cells in transplant (graft rejection and GvHD) reactions.
2