guidebook. - Fanconi Anemia Research Fund

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Fanconi Anemia: Guidelines for Diagnosis and Management
or her system. This is followed by one or more additional
glucose and insulin tests performed at specific
intervals to track glucose and insulin levels over time.
The OGTT may be ordered to help diagnose diabetes
and as a follow-up test to an elevated blood glucose. 3
Oropharynx: The part of the pharynx that is below the
soft palate and above the epiglottis and is continuous
with the mouth. 1
Osteosarcoma: A malignant tumor derived from bone
or containing bone tissue; also called osteogenic sarcoma.
1
Osteotomy: A surgical operation in which a bone is
divided or a piece of bone is excised (as to correct a
deformity). 1
Otoacoustic emission test (OAE): A test that can show
whether parts of the ear respond properly to sound.
During this test, a sponge earphone is placed into the
ear canal. The ear is stimulated with sound, and the
echo is measured. The echo is found in everyone who
hears normally. If there is no echo, it could indicate a
hearing loss. 21
Ototoxic: Having an adverse effect on organs or nerves
involved in hearing or balance. 5
Oxidative stress: Physiological stress on the body that
is caused by the cumulative damage done by free radicals
inadequately neutralized by antioxidants and that is
held to be associated with aging and several congenital
conditions, such as Fanconi anemia. 1
Pancytopenia: Abnormally low number of red and
white cells and platelets. 2