guidebook. - Fanconi Anemia Research Fund

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Fanconi Anemia: Guidelines for Diagnosis and Management
Avascular necrosis (AVN): Avascular necrosis occurs
when part of the bone does not get blood and dies. If
this condition is not treated, bone damage gets worse.
Eventually, the healthy part of the bone may collapse. 5
Azospermia: Lack of sperm. 1
B cells: Type of lymphocytes responsible for antibody
production.
Baseline test: Test which measures an organ’s normal
level of functioning. Used to determine if any changes
in organ function occur following treatment. 2
Basophil: Type of white blood cell; a type of granulocyte,
involved in allergic reactions. 2
Bicornuate uterus: Commonly referred to as a heartshaped
uterus, is a type of a uterine malformation where
two horns form at the upper part of the uterus. 1 This
is one example of a congenital uterine malformation.
These malformations do not cause infertility. The extent
and location of the malformation can affect the likeliness
of a pregnancy reaching full-term. Sometimes
called hemi-uterus.
Bifid: Separated or cleft into two parts. In FA patients,
most commonly refers to a thumb abnormality.
Biliary: Of, relating to, or conveying bile. 1
Biliary ducts: Ducts by which bile passes from the
liver or gallbladder to the duodenum. 1
Bilirubin: A product that results from the breakdown
of hemoglobin. Total and direct bilirubin are usually
measured to screen for or to monitor liver or gallbladder
problems. 5