guidebook. - Fanconi Anemia Research Fund

Chapter 1: Clinical Management Checklist
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include the nasopharynx, oropharynx,
hypopharynx, and larynx.
▫▫
Maintain good oral hygiene.
▫▫
Avoid all alcohol, including mouthwashes
that contain alcohol, and avoid
tobacco use, including second-hand
smoke.
▫▫
Consider an HPV vaccination, beginning
at age nine for both boys and girls, to
possibly prevent squamous cell carcinoma
associated with the HPV virus (see
Chapter 13).
• Treatment and surveillance:
▫▫
Suspicious lesions should be biopsied
immediately. If a premalignant lesion is
found, examinations should increase to
every two to three months, at the physician’s
discretion. Malignant lesions must
be treated immediately.
▫▫
Aggressive monitoring by the surgeon
is an absolute must for those already
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Dental Care
treated for head and neck cancer.
Those already treated for head and neck
cancer should obtain an annual chest
x-ray.
• Regular dental examinations: All FA patients
should have regular dental examinations by a
dental practitioner versed in FA cancer risks.
The examination should include a thorough
screening for possible oral cancer.
• Post-transplant: Because of the risk of bacteremia,
patients should not have dental cleaning,
extraction or other invasive procedures