guidebook. - Fanconi Anemia Research Fund

Chapter 11: Late Effects in FA Patients Post-Transplant
233
Return Visit
Post-Transplant
1
year
2
year
3
year
4
year
5
year
Every
year
Every
5 years
Pulmonary
Pulmonary
function tests with
DLCO (carbon
monoxide
X R R R X C
diffusing
capacity)
Hepatic Function
ALT, AST,
bilirubin, Alkaline
Phosphatase,
X X X X X
Albumin
Hep B sAg, Hep
B sAb, Hep C Ab
X
C
Renal
BUN, Cr,
Urinalysis
X X X X X X
Immunology
T-cell subset X
Ig G, A, M, E X R R R R R
Immunizations
including HPV f X X
ENT X X X X X X
Dental every 6
months
X X X X X X
Gynecology
X X X X X X
(females ≥13 yr)
Dermatology C C C
Audiology C C C C
Ophthalmology C C C C
If BRCA2, head
MRI, renal
ultrasound
Quality of life
assessment
X X X X X X
X X X X
X = to be done.
C = consider; check with MD.
R = repeat if previously abnormal.
†Repeat annually until full pubertal development achieved.
a
If mixed chimerism, follow BM ± PB chimerism beyond two years.
b
See text for details; if high, consider phlebotomy or chelation.
c Assess at puberty if not already being performed.
d When >18 years of age.
e If considered high risk, e.g.,