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National Project Implementation Plan - NVBDCP

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elimination target in at least half of these districts at the sub district level.<br />

This will contribute to the achievement of the national goal since the project<br />

focus will be on the districts that contribute maximally to the cases of Kalaazar<br />

in India.<br />

6.1.1 Sub Component 2.a: Improving Kala-azar Case Management<br />

6.1.1 2.a. a) Early diagnosis, complete treatment and referral<br />

Early diagnosis and complete treatment strategy would help elimination of<br />

the parasite, reduce case fatality rates and increase the credibility of the<br />

health system, which in turn will help to increase the utilization of health<br />

services by people affected by Kala-azar<br />

The case definition of kala –azar will be uniformly applied. A case of kalaazar<br />

is a person from an endemic area who has fever of more than 2 weeks<br />

with splenomegaly and positive dipstick test. All Patients suspected to be<br />

suffering from kala-azar should be tested by dipstick test. Confirmation of<br />

Kala-azar cases can be done by examination of bone marrow aspiration in<br />

hospital settings since these are envisage. However, this would be required<br />

in a few patients only since dipstick test is quite reliable. Once diagnosed,<br />

Miltefosine a safe oral drug will be administered under direct observation. In<br />

order to retain its efficacy and delay the appearance of drug resistance,<br />

treatment cards and patient wise box would be made available at the<br />

treatment point. Drug can not be used during early pregnancy and married<br />

women in reproductive age who do not use contraception regularly and in<br />

infants. The programme will undertake pharmaco vigilance as a part of<br />

efforts to maintain the usefulness of this drug in the programme for a long<br />

time. Miltefosine will be introduced in 16 districts. In other districts, SSG<br />

will continue to be used provided that the resistance level to SSG is less<br />

than 10%. Monitoring of side effects and management of side effects will be<br />

intensified to minimize the complications from this drug. Efforts will be<br />

made to intensify completion of medicine and the use of rescue drugs if<br />

there is unresponsiveness and toxicity from SSG. In the districts where<br />

resistance levels are higher than 10%, amphotericin B will be used as<br />

recommended by the national programme.<br />

The activity schedule for the first year is presented in Table 1. A detailed<br />

log-frame for subsequent years will be developed later, based on lessons<br />

learnt in the six months of implementation.<br />

44

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