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ALPI new opening in Prato - Alpi World

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26<br />

Withcare<br />

the Sandro Pitigliani association<br />

for the Fight aga<strong>in</strong>st Cancer.<br />

The Association “Sandro Pitigliani for the fight<br />

aga<strong>in</strong>st cancer” was founded (accord<strong>in</strong>g to the<br />

wishes of family and friends) after the death of<br />

Sandro from this illness. The Association began <strong>in</strong><br />

1979 with the aim of giv<strong>in</strong>g to the residents of <strong>Prato</strong><br />

affected by this illness the possibility of appropriate<br />

oncology care <strong>in</strong> the local hospital, and therefore<br />

close to their homes and those of their families. The<br />

aim of the centre has been to provide all therapy<br />

that <strong>in</strong> some way may help to overcome or improve<br />

this illness.<br />

The residents of <strong>Prato</strong> have shared and supported<br />

this <strong>in</strong>itiative with donations over the years that<br />

have allowed, with permission by the Hospital, the<br />

dedicated reconstruction of a build<strong>in</strong>g adjacent to<br />

the hospital, and construction of outpatient cl<strong>in</strong>ics, a<br />

day hospital designed for outpatient adm<strong>in</strong>istration<br />

of chemotherapy and f<strong>in</strong>ally an <strong>in</strong>patient ward,<br />

<strong>in</strong>clusive of sterile rooms.<br />

In recent years the Association, as well as f<strong>in</strong>anc<strong>in</strong>g<br />

build<strong>in</strong>g restructur<strong>in</strong>g and acquir<strong>in</strong>g equipment to<br />

improve the facilities and make more comfortable the<br />

stay of the patients, has undertaken, with Hospital<br />

Management, to create a Sandro Pitigliani Centre<br />

of Research. This last achievement has allowed the<br />

Department of Oncology to feature as one of the few<br />

oncology units <strong>in</strong> Italy to undertake research with<strong>in</strong><br />

the hospital environment.<br />

A turn<strong>in</strong>g po<strong>in</strong>t was the arrival to the Hospital of Dr<br />

Angelo Di Leo, Medical Oncologist and Researcher,<br />

with an extensive work curriculum and experience<br />

<strong>in</strong> cl<strong>in</strong>ical trials <strong>in</strong> Italy and abroad. In 2003,<br />

he was appo<strong>in</strong>ted as director of Department of<br />

Medical Oncology and the Department of Oncology<br />

Research. The acquisition and implementation of<br />

the CellSearch System <strong>in</strong> 2006, supported by the<br />

Hospital Adm<strong>in</strong>istration and <strong>in</strong> close collaboration<br />

with the Department of Anatomical Pathology,<br />

enabled the <strong>in</strong>itiation of Translational Research.<br />

The prelim<strong>in</strong>ary results obta<strong>in</strong>ed with this <strong>new</strong><br />

diagnostic tool, reported by the research team at<br />

various national and <strong>in</strong>ternational conferences, have<br />

provided important and valuable data. In 2008, this<br />

research earned a research grant of 250,000 USD<br />

from the Breast Cancer Research Foundation <strong>in</strong> New<br />

York. Our Department was the only unit <strong>in</strong> Italy to<br />

receive this prestigious grant.<br />

In 2008, <strong>in</strong> ongo<strong>in</strong>g collaboration with Hospital<br />

Management, the research unit became the “Centre<br />

of Oncology Research Sandro Pitigliani”. With<br />

Declaration N. 334 del 08/04/2009 from the Hospital<br />

of <strong>Prato</strong> Management USL4, the Translational<br />

Research Unit (TRU) was activated. The aim of<br />

the TRU is cl<strong>in</strong>ical research, aimed at rapidly<br />

transferr<strong>in</strong>g discoveries from the laboratory to the<br />

cl<strong>in</strong>ical sett<strong>in</strong>g (the “from the bench to the bedside”<br />

approach).<br />

The objectives of the research emerg<strong>in</strong>g from the<br />

TRU are (a) to <strong>in</strong>dividualise molecular profiles<br />

predictive of a response to medical treatment,<br />

and (b) to identify molecular markers associated<br />

with the presence of residual microscopic disease.<br />

Breast cancer is the pr<strong>in</strong>cipal focus of the research<br />

be<strong>in</strong>g undertaken <strong>in</strong> the TRU. The TRU operates<br />

with<strong>in</strong> the ‘Istituto Toscano Tumori’ and benefits<br />

from collaboration with other organisations of<br />

the ‘Istituto’, and with the Scientific Director and<br />

Operations Director of the ‘Istituto Toscano Tumori’

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