African Traditional Herbal Research Clinic STD's ... - Blackherbals.com

Meds that extend Lives of HIV
Patients tied to Diabetes
Protease inhibitors affect how body controls blood sugar,
researchers find
November 23, 2010
ST. LOUIS — Researchers at the Washington University
School of Medicine say they have uncovered why so
many people with the HIV virus develop a dangerous
insulin resistance that leads to diabetes and heart disease.
The culprit lies in the powerful drugs that prevent the
development of AIDS and have extended the lives of
many HIV patients, the researchers say. They hope the
discovery will allow development of safer antiviral drugs.
The research, published this month in the Journal of
Biological Chemistry, shows HIV protease inhibitor
drugs directly interfere with the way blood sugar levels
are controlled in the body. This leads to insulin
resistance, a condition that occurs when the body
produces enough insulin but doesn't use it properly.
Paul Hruz, a professor of pediatrics and biology at the
School of Medicine, led a team that found firstgeneration
protease inhibitors, including the drug
ritonavir, a protein that transports glucose from the blood
into the cells where it is needed.
This raises blood sugar levels, a hallmark of diabetes.
"Our lab has established that one of the effects of these
drugs is blocking glucose transport, one of most
important steps in how insulin works," Hruz said in a
statement on Tuesday. "Now that we've identified the
main mechanism, we will look to develop new drugs that
treat HIV but don't cause diabetes."
Hruz said that about 25 percent of HIV patients develop
diabetes. The team is working with a drug developer to
create a new HIV drug that the virus does not develop
resistance to.
Human Immunodeficiency Virus (HIV) is a virus the
human immune system can't rid itself of on its own. It
attacks a key part of the immune system, leaving the
body open to infections and diseases including AIDS,
which is the final stage of the disease.
The government estimates there are more than 56,000
new cases of HIV a year and more than 25 million people
have died of AIDS since it was first recognized by the
U.S. Centers for Disease Control in 1981.
http://www.msnbc.msn.com/id/40345008/ns/health-aids/
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HIV Treatment: Why
Children’s Cholesterol
Levels Are High
August 04, 2011
HIV treatment has come a long way since AIDS was
discovered in 1982. More than 1,000 children a day are
diagnosed worldwide. High cholesterol is common in
adults and children with HIV. As reported yesterday,
recent research has found children with HIV typically
still have high cholesterol levels during treatment with
antiretroviral medications according to JAIDS: Journal
of Acquired Immune Deficiency Syndromes. What this
means is that children who are unfortunate enough to
be HIV-positive still run the risk of developing
cardiovascular problems as a result of their treatment.
According to a recent press release, “The new research
highlights the ‘urgent need’ for specific guidelines to
manage lipid levels and control long-term
cardiovascular risks in children with HIV, according to
an editorial by Dr. Allison C. Ross of Emory
University, Atlanta, and Dr. Grace A. McComsey of
Case Western Reserve University, Cleveland.”
With the new antiviral drugs available, children with
HIV are now expected to have much longer lives. The
problem is that if these drugs put these children at a
greater risk for cardiovascular problems, then these
children could face new and other problems. As
reported, the researchers “believe the best strategy is
likely to be a combined approach consisting of a ‘lipidfriendly’
drug regimen along with non-drug treatments
(such as diet and exercise). More research is needed to
evaluate these and other strategies — including the role
of cholesterol-lowering medications.”
http://fyiliving.com/health-news/hiv-treatment-why-childrencholesterol-levels-are-high/
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Drugs for HIV Infection and
AIDS Might Prematurely Age
Brains
By S. L. Baker
February 2, 2010
(NaturalNews) In a report just published online in The
Journal of Infectious Diseases, scientists at Washington
University School of Medicine in St. Louis and the
Continued on page 44
-43- Traditional African Clinic October 2011