GASTRIC CANCER Risk Factors And Pathology

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Gastric Intestinal Metaplasia and Surveillance • Extensive Atrophic gastritis and intestinal metaplasia: – 10 year surveillance 8.4% developed gastric cancer – Recommend annual surveillance -Whiting et al. Gut 2003;50:378-81
Treating H. pylori gastritis before and after diagnosis of gastric cancer • H. pylori gastritis is treated with antibiotics • H. pylori eradication reduced the incidence of gastric cancer in patients without atrophy or IM, suggesting that eradication may contribute to preventing progression to gastric cancer – Wong et al. JAMA 291, 187-94, 2004 • Recent studies recommend prophylactic H. pylori eradication after resection of early gastric cancer to reduce the risk of carcinoma in the remnant stomach Fukase et al. Japan Gast Study Group Lancet 372: 392–97, 2008
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Page 3 and 4: Gastric Cancer LOCATION Cardia Fund
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GASTRIC CANCER Risk Factors And Pathology

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