CST Guide:
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32<br />
Section IV: Additional Information<br />
Diagram & Table Keys<br />
and additional resources<br />
Applications Key<br />
While all of our antibodies are rigorously tested in a number of relevant applications, some products are more suitable<br />
for a specific application. This information is summarized in various lists and tables found throughout this guide.<br />
chapter 32: Diagram & Table Keys<br />
Pathway Diagram Key<br />
The pathway diagrams found in this guide and on our website have been assembled by <strong>CST</strong> scientists and outside<br />
experts to provide succinct and current overviews of selected signaling pathways.<br />
Direct Stimulatory Modification<br />
Direct Inhibitory Modification<br />
Deacetylase<br />
Ribosomal subunit<br />
WB Western Blotting<br />
IP Immunoprecipitation<br />
IHC Immunohistochemistry<br />
IF Immunofluorescence<br />
F Flow Cytometry<br />
ChIP Chromatin Immunoprecipitation<br />
-IC Immunocytochemistry<br />
-P Paraffin<br />
-F Frozen<br />
E-P Peptide ELISA<br />
Multistep Stimulatory Modification<br />
Multistep Inhibitory Modification<br />
Tentative Stimulatory Modification<br />
Tentative Inhibitory Modification<br />
Separation of Subunits<br />
or Cleavage Products<br />
Joining of Subunits<br />
Translocation<br />
Transcriptional Stimulatory Modification<br />
Transcriptional Inhibitory Modification<br />
Kinase<br />
Phosphatase<br />
Transcription Factor<br />
Caspase<br />
Receptor<br />
Enzyme<br />
pro-apoptotic<br />
pro-survival<br />
GAP/GEF<br />
GTPase<br />
G-protein<br />
Acetylase<br />
TIM-3<br />
Galectin-9<br />
B7-H3<br />
B7-H4<br />
CTLA-4<br />
CD80, 86<br />
PD-1<br />
PD-L1<br />
TCR<br />
MHC<br />
ICOS<br />
ICOSL<br />
OX40<br />
OX40L<br />
CD40<br />
CD40L<br />
CD27<br />
CD70<br />
CD137<br />
CD137L<br />
CD28<br />
Reactivity Key<br />
H human<br />
M mouse<br />
R rat<br />
Hm hamster<br />
Mk monkey<br />
C chicken<br />
Mi mink<br />
Dm D. melanogaster<br />
X Xenopus<br />
Z zebra fish<br />
Amino Acid Properties Table<br />
B bovine<br />
Dg dog<br />
Pg pig<br />
Sc S. cerevisiae<br />
Name<br />
Single<br />
Abbreviation letter code MW pKa Codons<br />
Side chain<br />
characteristics Modifications<br />
Glycine Gly G 57.05 na G-G-(UCAG) Nonpolar<br />
Alanine Ala A 71.09 na G-C-(UCAG) Nonpolar<br />
Valine Val V 99.14 na G-U-(UCAG) Nonpolar<br />
Leucine Leu L 113.16 na C-U-(UCAG), U-U-(AG) Nonpolar<br />
Isoleucine Ile I 113.16 na A-U-(UCA) Nonpolar<br />
Phenylalanine Phe F 147.18 U-U-(UC) Nonpolar<br />
Proline Pro P 97.12 na C-C-(UCAG) Nonpolar Racemization<br />
Serine Ser S 87.08 16 A-G-(UC), U-C-(UCAG) Hydroxyl group Phospho-, Glycosyl-,<br />
Eliminyl-<br />
Threonine Thr T 101.11 7.6 A-C-(UCAG) Hydroxyl group Phospho-, Glycosyl-,<br />
Eliminyl-<br />
Tyrosine Tyr Y 163.18 na U-A-(UC) Hydroxyl group Adenyl-, Phospho-,<br />
Sulfo-<br />
Cysteine Cys C 103.15 8.35 U-G-(UC) Contains sulfur Eliminyl-<br />
Methionine Met M 131.19 na A-U-G Contains sulfur<br />
Asparagine Asn N 114.11 na A-A-(UC) Contains nonbasic<br />
nitrogen<br />
Glutamine Gln Q 128.14 na C-A-(AG) Contains nonbasic<br />
nitrogen<br />
Tryptophan Trp W 186.21 na U-G-G Contains nonbasic<br />
nitrogen<br />
Aspartic Acid Asp D 115.09 3.9 G-A-(UC) Acidic<br />
Glutamic Acid Glu E 129.12 4.07 G-A-(AG) Acidic<br />
All all species<br />
expected<br />
( ) 100% sequence<br />
homology<br />
Glycosyl-, Deamidation<br />
Deamidation<br />
Lysine Lys K 128.17 10.79 A-A-(AG) Basic Acetyl-, Adenyl-,<br />
Carbamyl-, Methyl-<br />
Ubiquitin, SUMO, ISG,<br />
Neddy, UFM1<br />
Arginine Arg R 156.19 12.48 A-G-(AG), C-G-(UCAG) Basic Methyl-, Citrulline<br />
Histidine His H 137.14 8.04 C-A-(UC) Basic Adenyl-, Phospho-<br />
302 For Research Use Only. Not For Use in Diagnostic Procedures.<br />
303
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