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Lung function measurements in children - copsac

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Title: Causal Direction between Respiratory Syncytial Virus Bronchiolitis and Asthma<br />

Studied <strong>in</strong> Monozygotic Tw<strong>in</strong>s<br />

Authors: Porntiva Poorisrisak, MD, a+b Liselotte Brydensholt Halkjaer, MD, PhD, a Simon<br />

Francis Thomsen, MD, PhD, c Lone Graff Stensballe, MD, PhD, d Kirsten Ohm Kyvik, MD,<br />

PhD, e Axel Skytthe MSci, PhD, f Peter Oluf Schioetz, MD, DMSci, g and Hans Bisgaard, MD,<br />

DMSci a<br />

Affiliations: a Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte,<br />

DK-2900, Denmark; b Department of Pediatrics, Naestved Hospital, DK-4700, Denmark;<br />

c Department of Respiratory Medic<strong>in</strong>e, Bispebjerg Hospital, Copenhagen, DK-2400, Denmark;<br />

d Bandim Health Project, Statens Serum Institut, Copenhagen, DK-2300, Denmark; e Institute<br />

of Regional Health Research and The Danish Tw<strong>in</strong> Registry, University of Southern<br />

Denmark, DK-5000 Odense C, Denmark; f Epidemiology, Institute of Public Health and The<br />

Danish Tw<strong>in</strong> Registry, University of Southern Denmark, DK-5000 Odense C, Denmark; and<br />

g Danish Pediatric Asthma Center, Aarhus University Hospital, Skejby, DK-8200, Denmark<br />

Correspondence: Hans Bisgaard, Danish Pediatric Asthma Center, Copenhagen University<br />

Hospital, Gentofte, L213, Ledreborg alle 34, DK-2820 Copenhagen, Denmark. Telephone:<br />

+45 3977 7360. Fax: +45 3977 7129. E-mail: Bisgaard@<strong>copsac</strong>.dk<br />

Key words: Children; Follow-up Study; Respiratory Function Test.<br />

Supported by MedImmune with an unrestricted <strong>in</strong>stitutional grant and The Danish Pediatric<br />

Asthma Center.<br />

Short runn<strong>in</strong>g title: Tw<strong>in</strong> study: Causal Direction between Respiratory Syncytial Virus<br />

Bronchiolitis and Asthma<br />

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