Lung function measurements in children - copsac

Aims (study I)
Study I
A. To determine the center agreement by comparing sRaw measurements in
healthy preschool children between 6 centers in Denmark currently using
identical hardware equipment, but different software versions.
B. Provide sRaw values for non-asthmatic preschool children at 5 of the centers
to expand normative data.
Material
Study I
We used 7 healthy preschool children as biological controls in the center agreement
study. The children were between 4.9 to 6.6 years old. None of the children had a
history of asthma or allergy. Three children previously had atopic dermatitis; three had
parental atopy and none had smoking parents.
In the normative data we recruited healthy preschool children by random selection
through the Central Person Registry from the local catchment area of 5 centers.
Approximately 20% of the families responded positively to the posted invitations.
105 non-asthmatic preschool children (52 male) were measured locally at one of the 5
centers; mean age was 5.1 years (interquartile range 4.3-6.0). One child was of Latin-
America descent and two of Arabic descent.
Children included were born at term, with no history of asthma related symptoms, other
chronic lung symptoms or use of asthma treatment. If the child had a lower respiratory
tract infection within the week before the appointment, the measurement was
rescheduled.
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