Lung function measurements in children - copsac
Lung function measurements in children - copsac
Lung function measurements in children - copsac
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Aims (study I)<br />
Study I<br />
A. To determ<strong>in</strong>e the center agreement by compar<strong>in</strong>g sRaw <strong>measurements</strong> <strong>in</strong><br />
healthy preschool <strong>children</strong> between 6 centers <strong>in</strong> Denmark currently us<strong>in</strong>g<br />
identical hardware equipment, but different software versions.<br />
B. Provide sRaw values for non-asthmatic preschool <strong>children</strong> at 5 of the centers<br />
to expand normative data.<br />
Material<br />
Study I<br />
We used 7 healthy preschool <strong>children</strong> as biological controls <strong>in</strong> the center agreement<br />
study. The <strong>children</strong> were between 4.9 to 6.6 years old. None of the <strong>children</strong> had a<br />
history of asthma or allergy. Three <strong>children</strong> previously had atopic dermatitis; three had<br />
parental atopy and none had smok<strong>in</strong>g parents.<br />
In the normative data we recruited healthy preschool <strong>children</strong> by random selection<br />
through the Central Person Registry from the local catchment area of 5 centers.<br />
Approximately 20% of the families responded positively to the posted <strong>in</strong>vitations.<br />
105 non-asthmatic preschool <strong>children</strong> (52 male) were measured locally at one of the 5<br />
centers; mean age was 5.1 years (<strong>in</strong>terquartile range 4.3-6.0). One child was of Lat<strong>in</strong>-<br />
America descent and two of Arabic descent.<br />
Children <strong>in</strong>cluded were born at term, with no history of asthma related symptoms, other<br />
chronic lung symptoms or use of asthma treatment. If the child had a lower respiratory<br />
tract <strong>in</strong>fection with<strong>in</strong> the week before the appo<strong>in</strong>tment, the measurement was<br />
rescheduled.<br />
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