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Lung function measurements in children - copsac

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Neonatal <strong>Lung</strong> Function and Bronchial Responsiveness Prior to Respiratory Syncytial Virus Bronchiolitis<br />

Authors: Porntiva Poorisrisak, MD, 1+2 and Hans Bisgaard, DMSci 1<br />

Affiliations:<br />

1 University of Copenhagen<br />

Copenhagen Prospective Study on Asthma <strong>in</strong> Childhood (COPSAC)<br />

A Lundbeck Foundation Centre for Translational Cl<strong>in</strong>ical Research<br />

Gentofte Hospital<br />

DK-2820 Copenhagen, Denmark<br />

2 Department of Pediatrics<br />

Naestved Hospital<br />

DK-4700 Naestved, Denmark<br />

Abbreviations: CI = Confidence Interval; COPSAC = COPenhagen Studies on Asthma <strong>in</strong> Childhood;<br />

ELISA = Enzyme-L<strong>in</strong>ked IimmunoSorbent Assay; FEV 0.5 = Forced Expiratory Volume at 0.5<br />

seconds; PD 15 = Provocative Dose of methachol<strong>in</strong>e produc<strong>in</strong>g a 15 percent fall <strong>in</strong> PtcO 2 ; OR = odds<br />

ratio; PtcO 2 = Transcutaneuous Oxygen Pressure; RSV = Respiratory Syncytial Virus; RVRTC =<br />

Raised Volume Rapid Thoraco-abdom<strong>in</strong>al Compression; SD = Standard Deviation<br />

Keywords: <strong>in</strong>fants; lung <strong>function</strong> <strong>measurements</strong>; respiratory syncytial virus; bronchiolitis<br />

None of the authors have conflicts of <strong>in</strong>terest to disclose.<br />

Correspond<strong>in</strong>g author: Hans Bisgaard, Copenhagen Prospective study on Asthma <strong>in</strong> Children,<br />

Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Ledreborg Alle 34,<br />

DK-2820 Gentofte, Denmark. Telephone: +45 39 77 73 60. Fax: +45 39 77 71 29. E-mail: Bisgaard@<strong>copsac</strong>.<br />

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