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NEWS<br />

page 5 issue four<br />

Products<br />

ENCOURAGING SIGNALS ON<br />

CROSS-PROTECTION AGAINST S. JAVA<br />

Clean-up pattern in 8 trial houses from a 100% S. Java-positive farm<br />

Strain-specific vaccines against S. Java are not available in the<br />

market, but some cross-protection from vaccination against<br />

Salmonella Typhimurium is expected, for both serotypes are<br />

categorised under group B of Salmonellae (Kaufmann-White<br />

scheme). In Germany and the Netherlands, AviPro ® SALMONELLA<br />

VAC T, <strong>Lohmann</strong>’s live vaccine for drinking water against<br />

S. Typhimurium, has been used in several field trials to investigate<br />

its aid in the control of S. Java. Farms with good biosecurity,<br />

hygiene control and a monitoring programme for Salmonella spp.<br />

used our ST vaccine for several cycles of broilers.<br />

The results have generally shown that sequential rounds of<br />

vaccination may help cleanup the farm of S. Java.<br />

Salmonella paratyphi B, variation Java (better known as<br />

Salmonella Java) is an increasing problem in chicken farms, a fact<br />

which constitutes a potential threat to public health. The bacteria<br />

may persist on farms despite adequate quality control scores,<br />

appearing again in subsequent chicken flocks (broilers) even after<br />

adequate disinfection procedures. It is believed that the bacteria<br />

may be harboured by unknown reservoirs, which, under sequential<br />

rounds of vaccination, would also be cleaned up, together with the flocks.<br />

These are not only encouraging indicators of cross-protection<br />

of this remarkable vaccine against S. Java, but they also point<br />

out that vaccination only may not be sufficient for a complete<br />

Salmonella control programme. Other preventive measures, such<br />

as clean feeds and water, hygiene, biosecurity and monitoring,<br />

will complete the shield of protection around the birds.<br />

Note: AviPro ® SALMONELLA VAC T does not have a registered claim against S. Java.<br />

Products<br />

FOR CHICKEN ANAEMIA – NO BETTER<br />

PREVENTION THAN THYMOVAC<br />

A serology profile (CAV titres) for breeders and their progeny was<br />

studied by Dr Beatriz Cardoso and Dr Lindolfo Rocha, both based<br />

in the LAH office in Brazil. The study tried to verify a correlation<br />

between breeder titres and progeny titres; difference between<br />

immunisation programmes (drinking water vaccine AviPro ®<br />

THYMOVAC; injected competitor’s vaccine; and naturally infected<br />

breeders); and a correlation between day-of-age titres and<br />

actual CAV field problems. Several flocks from different companies<br />

were studied. Serum was collected at least during 3 different<br />

ages and day-old chicks were tested also from differently aged<br />

flocks. Data was compared to broiler performance.<br />

The results confirmed:<br />

Direct correlation between consistency and uniformity of<br />

breeder titres with progeny titres<br />

For broiler flocks CAV negative at slaughter, no difference in<br />

performance made the titre level at day-of-age<br />

Higher titres at day-of-age<br />

presented better performance<br />

results among broiler flocks<br />

which were CAV positive at<br />

slaughter<br />

Birds vaccinated with AviPro ®<br />

THYMOVAC had the most<br />

consistent, long-lasting titres<br />

in breeders and the higher<br />

averaged titres in the progeny<br />

at day-of-age, compared to<br />

the injected vaccine or to<br />

naturally infected flocks<br />

Protection with AviPro® THYMOVAC<br />

Vaccination stops the spread<br />

of wild virus among breeders<br />

and vertical transmission<br />

The study was presented by Dr Cardoso at the American<br />

Association of Avian Pathologists’ annual conference in<br />

Honolulu in 2006.

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