Microbial Diseases of the Digestive System
Microbial Diseases of the Digestive System Microbial Diseases of the Digestive System
Toxin • Shiga toxin - Kiyoshi Shiga • Unusually virulent • Bacteria invade intestinal mucosa – produce toxin • Severe diarrhea with blood in stool (dysentery) • Toxin inhibits Protein Synthesis • Cells lining G.I. tract are shed • Up to 20 bowels movements a day
20,000 – 30,000 cases per year in U.S. 5 – 15 deaths Shigella dysenteriae – more severe - Mortality Rate = 20 %
- Page 1 and 2: Microbial Diseases of the Digestive
- Page 3 and 4: Bacterial Diseases of Lower G.I.
- Page 5 and 6: Campylobacter Gastroenteritis • C
- Page 7: Shigellosis (Bacillary Dysentery)
- Page 11: Salmonellosis • Incubation time 1
- Page 14 and 15: Salmonellosis • Contamination •
- Page 16 and 17: Typhoid Mary • Mary Mallon - cook
- Page 18 and 19: Food Poisoning from Seafood • Vib
- Page 20 and 21: * 1 million bacteria per gram of fo
- Page 22 and 23: Peptic Ulcers • Helicobacter pylo
- Page 24 and 25: Hepatitis A (Infectious Hepatitis)
- Page 26: Hepatitis C (Non A, Non B Hepatitis
Toxin<br />
• Shiga toxin - Kiyoshi Shiga<br />
• Unusually virulent<br />
• Bacteria invade intestinal mucosa – produce toxin<br />
• Severe diarrhea with blood in stool (dysentery)<br />
• Toxin inhibits Protein Syn<strong>the</strong>sis<br />
• Cells lining G.I. tract are shed<br />
• Up to 20 bowels movements a day
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