Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
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Dissolution and Absorption Pr<strong>of</strong>iles – Water as<br />
Dissolution Medium<br />
Drug Dissolution<br />
Drug Absorption<br />
100<br />
100<br />
Cumulative Percent Label Claim Dissolved<br />
80<br />
60<br />
40<br />
20<br />
Slow Release<br />
Medium Release<br />
Fast Release<br />
Cumulative Relative Percent Absorbed<br />
80<br />
60<br />
40<br />
20<br />
Slow Release<br />
Medium Release<br />
Fast Release<br />
0<br />
0<br />
0 2 4 6 8 10 12 14 16<br />
0 2 4 6 8 10 12 14 16<br />
Time (Hours)<br />
Time (Hours)