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Applications of IVIVC in Formulation Development - PQRI

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Plasma Concentrations Follow<strong>in</strong>g Oral<br />

Adm<strong>in</strong>istration<br />

5<br />

4<br />

<strong>Formulation</strong> B (Fast Release)<br />

<strong>Formulation</strong> A (Slow Release)<br />

<strong>Formulation</strong> C (Medium Release)<br />

Market Product Reference<br />

IR Reference<br />

[Drug] (ng/mL)<br />

3<br />

2<br />

1<br />

0<br />

0 6 12 18 24 30 36 42 48 54 60 66 72<br />

Time (Hours)

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