Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
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Mean Plasma Concentration-Time Pr<strong>of</strong>iles Follow<strong>in</strong>g<br />
Adm<strong>in</strong>istration <strong>of</strong> Low Dose Reformulation Candidates<br />
1400<br />
[Drug] (pg/mL)<br />
1200<br />
1000<br />
800<br />
600<br />
8.0% Polymer<br />
4.5% Polymer<br />
5.25% Polymer<br />
6.25% Polymer<br />
6.5% Polymer<br />
7.0% Polymer<br />
0% Polymer<br />
Reference<br />
400<br />
200<br />
0<br />
0 2 4 6 8 10 12 14 16 18 20 22 24<br />
Time (Hours)
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