Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
Applications of IVIVC in Formulation Development - PQRI
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<strong>IVIVC</strong> Model – Acetate Buffer as Dissolution<br />
Medium<br />
Cumulative Percent Absorbed<br />
100<br />
80<br />
60<br />
40<br />
Slow Release<br />
<strong>Formulation</strong><br />
Medium Release<br />
<strong>Formulation</strong><br />
Fast Release<br />
<strong>Formulation</strong><br />
Slow and Fast <strong>IVIVC</strong><br />
R 2 = 0.989<br />
20<br />
0<br />
0 20 40 60 80 100<br />
Cumulative Percent Dissolved