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RPVI Exam Vascular Physics Case Review.pdf - VascularWeb

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<strong>RPVI</strong> TM<br />

<strong>Exam</strong><br />

<strong>Vascular</strong> <strong>Physics</strong> <strong>Case</strong> <strong>Review</strong><br />

Frank R. Miele<br />

I have nothing to disclose!


<strong>Exam</strong> Overview: According to Outline<br />

I. Instrumentation and Ultrasound <strong>Physics</strong> (12-18%)<br />

A. Doppler equation<br />

B. Continuous-wave/Pulsed wave Doppler<br />

C. Spectral waveform analysis<br />

D. Color/Power Doppler<br />

E. B-mode imaging<br />

F. Artifacts<br />

VIII. Quality Assurance and Ultrasound Safety (2-8%)<br />

A. Test validation<br />

B. Bioeffects of ultrasound


General <strong>Exam</strong> Info:<br />

• There were 201questions<br />

• 196 questions counted<br />

• Passing was 122 Questions (62%)<br />

• There were many image and video<br />

(loop) based questions<br />

Topic # Q’s %<br />

Instr & <strong>Physics</strong> 58 28.9%<br />

Extracranial C 44 21.9%<br />

Intracranial 6 3.0%<br />

P Ven (Upper & Low) 32 15.9%<br />

P. Art (Upper & Low) 26 12.9%<br />

Visc Vasc 16 8.0%<br />

Special Testing 13 6.5%<br />

Q & A 6 3.0%<br />

Total 201<br />

• At least 3 Q’s: Color direction (with cineloop)<br />

• At least 4 Q’s involving Doppler equation<br />

• Lots of Q’s on Wavelength<br />

• Lots of Q’s on Transducers<br />

• Questions on aliasing in PW<br />

• Couple of power and time questions<br />

• 3 statistics (was not given table) Had to calculate on one.


Lecture Format<br />

I. Quiz Questions (subdivided by topic)<br />

II.<br />

Quiz answers and explanations (subdivided by topic)<br />

Quiz Scoring:<br />

• 3 points for each correct<br />

• 4 points for each correct foundational question<br />

• (max = 94 points)<br />

• Approximately 75% (score of 71) would be considered passing<br />

CME: www.<strong>Vascular</strong>Web.org


PREPARING FOR THE <strong>RPVI</strong> EXAM<br />

<strong>RPVI</strong> eCourses<br />

<strong>RPVI</strong> <strong>Exam</strong> Sims<br />

Go Online: SVU, SVS, or www.PegasusLectures.com


Doppler Equation<br />

QUESTIONS


Q1: Foundational Question<br />

Which of the following would not result in higher<br />

Doppler frequency shift<br />

A. Measuring flow velocity distal to a bend in the vessel<br />

B. Measuring the flow velocity slightly distal to a non flow reducing stenosis<br />

C. Using a Doppler angle of 50 degrees instead of 60 degrees<br />

D. Switching from a 6 MHz to a 4 MHz Doppler transmit frequency


Q2: Foundational Question<br />

Between what angles does the cosine change<br />

fastest<br />

A. 0 and 10 degrees<br />

B. 60 and 70 degrees<br />

C. 90 and 100 degrees<br />

D. 135 and 145 degrees<br />

E. All of the choices represent the same change


Q3: Question<br />

With respect to performing Doppler which statement<br />

is true regarding using a lower operating frequency<br />

A. the amount of scattering increases, making the blood easier to visualize<br />

directly.<br />

B. with the exception of shallow imaging, the sensitivity is significantly<br />

improved.<br />

C. aliasing becomes more likely.<br />

D. the peak velocity measurement accuracy degrades.


Q4: Doppler Angle<br />

Which of the following Doppler insonification angles would result in the<br />

greatest Doppler frequency shift<br />

A) 30<br />

B) 60<br />

C) 10<br />

<br />

<br />

<br />

D) 90<br />

<br />

E) 180


Doppler Equation<br />

ANSWERS


Doppler Equation<br />

Knowing the Doppler equation is critical:<br />

where:<br />

f Dop<br />

= Doppler shifted frequency (relative to transmit frequency)<br />

f 0<br />

v<br />

c<br />

= transmit frequency<br />

= velocity of target through medium<br />

= speed of interrogating beam through medium<br />

(c = 1540 m/sec for sound in tissue.)<br />

cos(θ) = mathematical correction for angle effect<br />

θ<br />

= insonification angle (or angle to flow)


Doppler Equation


Doppler Equation: Relative Relationships<br />

f<br />

Dop<br />

=<br />

2 fv o cos( θ )<br />

c<br />

f<br />

f<br />

f<br />

f<br />

Dop<br />

Dop<br />

Dop<br />

Dop<br />

∝<br />

∝<br />

∝<br />

∝<br />

v (blood velocity)<br />

f<br />

0<br />

cos<br />

(operating frequency)<br />

( θ )<br />

1 (propagation velocity)<br />

c<br />

*The starting point for answering almost all Doppler questions is the<br />

Doppler equation. You should know this equation cold!


Doppler Theory (Angle)<br />

The angular affect on the Doppler shift can be determined from the unit<br />

circle and the cosine function.<br />

y No change in λ<br />

1<br />

90°<br />

Longer λ<br />

180°<br />

-1 0<br />

0° = 360°<br />

x<br />

1<br />

x<br />

Shorter λ<br />

-1<br />

270°


Cosines


Doppler Theory (Angle)<br />

It is useful to know the cosine of the basic angles:<br />

y<br />

90°<br />

1<br />

Cosine (0°) = 1<br />

Cosine (30°) = 0.86<br />

Cosine (45°) = 0.707<br />

Cosine (60°) = 0.5<br />

Cosine (90°) = 0<br />

Cosine (180°) = -1<br />

180°<br />

-1 -.75 .-5 -.25 0 .25 .5 .75<br />

-1 -.75 .-5 -.25 0 .25 .5 .75<br />

270°<br />

60°<br />

45°<br />

30°<br />

1<br />

0° = 360°<br />

x


The Optimal Frequency for Doppler<br />

Recall the Scattering paradox:<br />

There is a tradeoff between increased reflectivity and increased<br />

absorption with a shorter wavelength from higher frequency operation.<br />

Notice that as the depth increases beyond 3 cm, the transmit frequency<br />

really should be set as low as possible for optimal sensitivity because of<br />

the dominance of absorption.


Q1: Foundational Answer<br />

Which of the following would not result in higher<br />

Doppler frequency shift<br />

A. Measuring flow velocity distal to a bend in the vessel<br />

B. Measuring the flow velocity slightly distal to a non flow reducing stenosis<br />

C. Using a Doppler angle of 50 degrees instead of 60 degrees<br />

D. Switching from a 6 MHz to a 4 MHz Doppler transmit frequency


Q2: Foundational Answer<br />

Between what angles does the cosine change fastest<br />

A. 0 and 10 degrees<br />

B. 60 and 70 degrees<br />

C. 90 and 100 degrees<br />

D. 135 and 145 degrees<br />

E. All of the choices represent the same change


Q3: Answer<br />

With respect to performing Doppler which statement<br />

is true regarding using a lower operating frequency<br />

A. the amount of scattering increases, making the blood easier to visualize<br />

directly.<br />

B. with the exception of shallow imaging, the sensitivity is significantly<br />

improved.<br />

C. aliasing becomes more likely.<br />

D. the peak velocity measurement accuracy degrades.


Q4: Answer<br />

Which of the following Doppler insonification angles would result in the<br />

greatest Doppler frequency shift<br />

A) 30<br />

B) 60<br />

C) 10<br />

<br />

<br />

<br />

D) 90<br />

<br />

E) 180


Continuous/PW<br />

QUESTIONS


Q5: Foundational Question<br />

What is the main motivation for using pulsed waves<br />

in ultrasound<br />

A. Better ability to detect peak velocities<br />

B. Higher speeds of sound, implying faster imaging (higher frame rates)<br />

C. Perfect depth discrimination<br />

D. Better contrast resolution<br />

E. Some depth discrimination


Q6: Question<br />

If the Doppler sample rate (the PRF) is 8 kHz, at<br />

what frequency will the peak Doppler shift become<br />

undetectable<br />

A. 8 kHz<br />

B. 4 kHz<br />

C. 2 kHz<br />

D. 16 kHz


Q7: Question<br />

Aliasing is occurring with the Doppler spectrum from a stenosed artery.<br />

Which change would decrease the likelihood of aliasing occurring<br />

A) Decrease the transmit power<br />

B) Increase the Doppler spectral sweep speed<br />

C) Increase the PRF<br />

D) Increase the sample volume (gate) size<br />

E) Decrease the transmit (operating) frequency


Q8: Question<br />

Given the following situation, will aliasing occur<br />

f = 6 MHz f = 9.3 kHz PRF = 12 kHz<br />

o<br />

Dop<br />

A) Yes, always<br />

B) Yes sometimes<br />

C) No<br />

D) Cannot be determined


Q9: Question<br />

f = 6 MHz f = 9.3 kHz PRF = 12 kHz<br />

o<br />

Dop<br />

If the operating frequency is changed to 2 MHz, will aliasing occur<br />

A) Yes, always<br />

B) Yes sometimes<br />

C) No<br />

D) Cannot be determined


Continuous/PW<br />

ANSWERS


CW, Range Ambiguity, and Aliasing


CW: No Range Resolution (Animation)


Range Specificity: PW (Animation)<br />

Notice that the echoes from each of the three mountains return at distinct<br />

times such that each mountain is resolved (range resolution).


SPL and Ambiguity (Animation)<br />

In this case, the pulse length is so long that the echoes from mountain 1<br />

and mountain 2 overlap, making it impossible to distinguish mountain 1<br />

from mountain 2. The echo from mountain 3 is still distinct since the<br />

separation between mountain 2 and mountain 3 is greater than the<br />

separation between mountain 2 and mountain 1.


Nyquist


Nyquist and Doppler<br />

f<br />

Dop<br />

Dop (max) PRF<br />

f =<br />

2<br />

=<br />

⇒<br />

⇒<br />

⇒<br />

2 fv∗<br />

cos<br />

o<br />

( θ )<br />

c<br />

Higher opertaing frequency<br />

Higher velocity<br />

Angles closer to<br />

<br />

0 or 180<br />

<br />

PRF<br />

1 1<br />

= =<br />

PRP ID( cm) ∗13μ<br />

sec<br />

⇒ Increasing Doppler Gate Depth


Q5: Foundational Answer<br />

What is the main motivation for using pulsed waves<br />

in ultrasound<br />

A. Better ability to detect peak velocities<br />

B. Higher speeds of sound, implying faster imaging (higher frame rates)<br />

C. Perfect depth discrimination<br />

D. Better contrast resolution<br />

E. Some depth discrimination


Q6: Answer<br />

If the Doppler sample rate (the PRF) is 8 kHz, at<br />

what frequency will the peak Doppler shift become<br />

undetectable<br />

A. 8 kHz<br />

B. 4 kHz<br />

C. 2 kHz<br />

D. 16 kHz


Q7: Answer<br />

Aliasing is occurring with the Doppler spectrum from a stenosed artery.<br />

Which change would decrease the likelihood of aliasing occurring<br />

A) Decrease the transmit power<br />

B) Increase the Doppler spectral sweep speed<br />

C) Increase the PRF<br />

D) Increase the sample volume (gate) size<br />

E) Decrease the transmit (operating) frequency<br />

Note – Bonus points for recognizing both correct answers


Q8: Answer<br />

Given the following situation, will aliasing occur<br />

f = 6 MHz f = 9.3 kHz PRF = 12 kHz<br />

o<br />

Dop<br />

Yes: aliasing begins at 6 kHz<br />

A) Yes, always<br />

B) Yes sometimes<br />

C) No<br />

D) Cannot be determined


Q9: Answer<br />

If the operating frequency is change to 2 MHz, will aliasing occur<br />

f = 6 MHz f = 9.3 kHz PRF = 12 kHz<br />

o<br />

Dop<br />

f = 2 MHz f = 3.1 kHz PRF = 12 kHz<br />

o<br />

Dop<br />

No: Doppler shift is now less than 6 kHz<br />

A) Yes, always<br />

B) Yes sometimes<br />

C) No<br />

D) Cannot be determined


Spectral Waveform Analysis<br />

QUESTIONS


Q10: Question<br />

What is the true peak velocity<br />

A. 67.5 cm/s<br />

B. 50 cm/s<br />

C. 100 cm/s<br />

D. 135 cm/s<br />

Specified Angle = 40 degrees<br />

Actual Angle = 55 degrees<br />

PSV = 67.5 cm/sec


Q11: Question<br />

What is the primary difference between these two spectra<br />

A) “A” represents a proximal obstruction<br />

B) “B” represents a proximal obstruction<br />

C) “A” represents a higher distal resistance<br />

D) “B” represents a higher distal resistance<br />

E) None of the above.<br />

A<br />

B


Q12: Foundational Question<br />

What happens if you use a wall filter setting that is too low<br />

What happens if you use a wall filter setting that is too high


Spectral Waveform Analysis<br />

ANSWERS


Clutter “Signals” and Dynamic Range<br />

DNR human eye<br />

Fig. 20: (Pg 545)<br />

Can you think of some structures in the body which create large “clutter” signals


Applying the Wall Filter<br />

Fig. 21: (Pg 546)


Wall Filter Saturation<br />

Saturation appears on the spectrum as a bright white signal relatively<br />

symmetric about the baseline. In the following spectrum, the circuit<br />

saturates as the specular reflection from the valve is evident for each<br />

cardiac cycle


Wall Filter (Animation)


Typical Wall Filter Settings<br />

The following are typical wall filter settings for various applications:<br />

< 25 – 50 Hz Venous<br />

50 – 100 Hz Arterial<br />

200 – 600 Hz Adult Echo<br />

600 – 800 Hz Pediatric Echo<br />

The correct wall filter frequency to use depends on the operating<br />

frequency of the transducer as well as the velocity of the desired signal<br />

and the undesired clutter.


Q10: Answer<br />

A. 67.5 cm/s<br />

B. 50 cm/s<br />

C. 100 cm/s<br />

D. 135 cm/s<br />

Angle = 40 degrees<br />

True Angle = 55 degrees<br />

PSV = 67.5 cm/sec<br />

(<br />

<br />

)<br />

(<br />

<br />

)<br />

v<br />

cos 40 0.766<br />

* 67.5 / 90.2 / sec<br />

cos 55<br />

cm s ⎛ ⎞<br />

= ∗ ⎜ =<br />

0.573<br />

⎟<br />

⎝ ⎠<br />

cm


Q11: Answer<br />

What is the primary difference between these two spectra<br />

A) “A” represents a proximal obstruction<br />

B) “B” represents a proximal obstruction<br />

C) “A” represents a higher distal resistance<br />

D) “B” represents a higher distal resistance<br />

E) None of the above.<br />

A<br />

B


Q12: Foundational Answers<br />

What happens if you use a wall filter setting that is too low<br />

Circuit saturation: Loud pops and bright white symmetric spikes in spectrum<br />

What happens if you use a wall filter setting that is too high<br />

Lower frequency shifts (velocity) signals can be eliminated


Color/Power Doppler<br />

QUESTIONS


Q13: Question<br />

Which of the following changes would most improve temporal<br />

resolution<br />

A. Decrease the color box width by 25%<br />

B. Decrease the 2D reference image by 50%<br />

C. Decrease the Color box depth by 25%<br />

D. Decrease the color packet size from 10 to 8 lines<br />

E. Decrease the color line density by 20%


Q14: Question<br />

In which Direction is the flow going<br />

A<br />

B<br />

C<br />

D<br />

• Fig. 54: (Pg 576)<br />

Cannot be determined<br />

E


Q15: Question<br />

In which direction is the flow<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Q16: Question<br />

Flow Direction<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Q17: Question<br />

A<br />

B<br />

C<br />

D<br />

• (Pg 580 E)<br />

Cannot be determined<br />

E


Q18: Question<br />

Regarding the following image, which of the following statements is not<br />

true<br />

A) Flow direction cannot be<br />

determined<br />

B) This technique is less sensitive to<br />

angle than standard color Doppler<br />

C) If color were used instead there<br />

would likely be a region of flow<br />

dropout<br />

D) This technique is generally pretty<br />

sensitive to low flow<br />

E) The different color hues represent<br />

different velocities


Color/Power Doppler<br />

ANSWERS


How Images are Produced & Transducers


*Note that not all systems have separate wall filter controls for color<br />

Doppler. Usually the wall filters are set as a percentage of the<br />

color scale setting.<br />

Interpreting The Color Bar<br />

The color bar can be compared with the format of the Doppler<br />

spectrum. The color bar presents both flow directionality and average<br />

flow velocities (or frequency shifts). As with spectral Doppler, the<br />

baseline represents no flow detected. Aliasing results in a “wrapping”<br />

of the colors around the baseline.<br />

Fig. 49: (Pg 573)


Identifying the Doppler (Insonification) Angle<br />

The Doppler insonification angle is always measured between the<br />

direction of the flow and the line of observation (Doppler steered<br />

line).


Doppler Insonification Angle = 0°<br />

The flow is directly toward the transducer, so the angle between<br />

the flow direction and the steered line is 0 degrees. The<br />

resulting Doppler shift is positive.


Doppler Insonification Angle = 180°<br />

The flow is directly away from the transducer, so the angle<br />

between the flow direction and the steered line is 180 degrees.<br />

The resulting Doppler shift is negative.


Doppler Insonification Angle = 30°<br />

The angle formed between the flow direction and the steered Doppler line<br />

is 30 degrees. Notice how the flow is traveling closer to the transducer,<br />

but not directly toward as when the angle was 0 degrees. As a result, less<br />

of the Doppler shift is detected at 30 degrees than at 0 degrees, but the<br />

shift is still positive.


Doppler Insonification Angle = 90°<br />

The angle formed between the flow direction and the steered Doppler<br />

line is 90 degrees. Notice how at the point where the beam intersects<br />

the flow, the flow is not traveling closer or farther away from the<br />

transducer, resulting in no frequency shift.


Determining Flow Direction<br />

Like spectral Doppler, the color direction is easily determined by<br />

analyzing the angle formed between the steered beam and the flow<br />

direction.<br />

+ V, + f Dop<br />

Angle less<br />

than 90º<br />

Flow Direction<br />

- V, - f Dop<br />

Steer<br />

Direction<br />

Direction chosen correctly<br />

Direction chosen<br />

incorrectly<br />

* The angle to flow is always measured between the steered beam<br />

direction and the head of the flow (where the flow is going to)


Q14: Answer<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Q15: Answer<br />

In which direction is the flow<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Q15: Continued<br />

In which direction is the flow<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Determining Flow Direction<br />

For the given color scale, when the angle between the head of the flow<br />

and the steered beam direction is less than 90 degrees, the flow is<br />

colored with hues of blue through aqua.


Q16: Answer<br />

Flow Direction<br />

A<br />

B<br />

C<br />

D<br />

Cannot be determined<br />

E


Q17: Answer<br />

A<br />

B<br />

C<br />

D<br />

• (Pg 580 E)<br />

Cannot be determined<br />

E


Q18: Answer<br />

Regarding the following image, which of the following statements is not<br />

true<br />

A) Flow direction cannot be<br />

determined<br />

B) This technique is less sensitive to<br />

angle than standard color Doppler<br />

C) If color were used instead there<br />

would likely be a region of flow<br />

dropout<br />

D) This technique is generally pretty<br />

sensitive to low flow<br />

E) The different color hues represent<br />

different velocities


B-Mode Imaging<br />

QUESTIONS


Q19: Foundational Question<br />

A typical wavelength in diagnostic ultrasound is:<br />

A) 300 micrometers<br />

B) 30 micrometers<br />

C) 300 millimeters<br />

D) 30 millimeters<br />

E) 30 nanometers


Q20: Question<br />

Higher frequency imaging results in better resolution because:<br />

A) there is better penetration.<br />

B) the wavelength is shorter.<br />

C) higher intensities can be used.<br />

D) the beams can be wider.<br />

E) more than one of the above is true.


Q21: Question<br />

Which of the listed mediums has the greatest<br />

absorption rate<br />

A. Bone<br />

B. Tendon<br />

C. Muscle<br />

D. Blood<br />

E. Fat


Q22: Question<br />

Which ultrasound modality has the worst temporal<br />

resolution<br />

A. CW Doppler<br />

B. PW Doppler<br />

C. B-Mode<br />

D. Color Doppler<br />

E. A-Mode


Q23: Question<br />

With the system controls set as show below, what<br />

will the image look like<br />

A. Appropriately gained<br />

B. Too bright in the near field<br />

C. Too bright in the far field<br />

D. Too dark in the near field<br />

E. Too dark in the far field<br />

Fig. 30: (Pg 328)


Q24: Foundational Question<br />

Compression is necessary:<br />

A. To reduce the dynamic range of the signal<br />

B. To decrease the range of frequencies in the signal<br />

C. To improve the signal to noise ratio<br />

D. To decrease the risk of bioeffects


Q25: Question<br />

Which statement about harmonic imaging is not<br />

true<br />

A. The second harmonic of 2 MHz is 4 MHz.<br />

B. Harmonic imaging generally results in less clutter artifacts in the image.<br />

C. Axial resolution usually gets better with harmonic imaging.<br />

D. Lateral resolution usually gets better with harmonic imaging.<br />

E. Harmonic imaging results in less penetration that fundamental imaging.


B-Mode Imaging<br />

ANSWERS


Wavelength Equation


Q19: Foundational Answer<br />

A typical wavelength in diagnostic ultrasound is:<br />

A) 300 micrometers<br />

B) 30 micrometers<br />

C) 300 millimeters<br />

D) 30 millimeters<br />

E) 30 nanometers<br />

From the wavelength equation, using 10 MHz as the upper frequency and 2.5<br />

MHz as the lower, it can be shown that typical wavelengths range from 154<br />

micrometers to 616 micrometers. Only choice A falls in that range.


Q20: Answer<br />

Higher frequency imaging results in better resolution because:<br />

A) there is better penetration.<br />

B) the wavelength is shorter.<br />

C) higher intensities can be used.<br />

D) the beams can be wider.<br />

E) more than one of the above is true.


Q21: Answer<br />

Which of the listed mediums has the greatest<br />

absorption rate<br />

A. Bone<br />

B. Tendon<br />

C. Muscle<br />

D. Blood<br />

E. Fat


Q22: Answer<br />

Which ultrasound modality has the worst temporal<br />

resolution<br />

A. CW Doppler<br />

B. PW Doppler<br />

C. B-Mode<br />

D. Color Doppler<br />

E. A-Mode


Q23: Answer<br />

A. Appropriately gained<br />

B. Too bright in the near field<br />

C. Too bright in the far field<br />

D. Too dark in the near field<br />

E. Too dark in the far field


Q24: Foundational Answer<br />

Compression is necessary:<br />

A. To reduce the dynamic range of the signal<br />

B. To decrease the range of frequencies in the signal<br />

C. To improve the signal to noise ratio<br />

D. To decrease the risk of bioeffects


Q25: Answer<br />

Which statement about harmonic imaging is not true<br />

A. The second harmonic of 2 MHz is 4 MHz.<br />

B. Harmonic imaging generally results in less clutter artifacts in the image.<br />

C. Axial resolution usually gets better with harmonic imaging.<br />

D. Lateral resolution usually gets better with harmonic imaging.<br />

E. Harmonic imaging results in less penetration that fundamental imaging.


Q&A: Test Validation<br />

QUESTIONS


Q26: Foundational Question<br />

With respect to statistical test validation and classification of test results<br />

as true positive, false positive, true negative, or false negative, the<br />

assumption is that<br />

A) the gold standard, although not perfect, is good enough.<br />

B) that the test is not as good as the gold standard.<br />

C) that the gold standard is perfect.<br />

D) that the gold standard is not as good as the test.<br />

E) There are more false results than true results.


Q27: Question<br />

Scary hospital vascular lab is validating their testing procedure predicting<br />

common carotid artery disease. The following results were obtained relative to<br />

the “gold standard”:<br />

‣ For the 71 times the test predicted disease, the test matched the gold<br />

standard 51 times.<br />

‣ For the 179 times the test predicted no disease, the test matched the gold<br />

standard 160 times<br />

Of the patients who were tested, how many have disease<br />

A) 160<br />

B) 71<br />

C) 70<br />

D) 51<br />

E) 20


Q28: Question<br />

Scary hospital vascular lab is validating their testing procedure predicting<br />

common carotid artery disease. The following results were obtained relative to<br />

the “gold standard”:<br />

‣ For the 71 times the test predicted disease, the test matched the gold<br />

standard 51 times.<br />

‣ For the 179 times the test predicted no disease, the test matched the gold<br />

standard 160 times<br />

For this test, statistically which is most likely<br />

A) to claim that a patient does not have disease when they do<br />

B) to be incorrect when positive for disease<br />

C) To incorrectly claim that a patient has disease when they do not<br />

D) To be incorrect when negative for disease


Q29: Question<br />

For a given test, the PPV is 81% the NPV is 88%, the sensitivity is 84%<br />

and the specificity is 90%, which statement is true regarding the overall<br />

accuracy.<br />

A) The accuracy must be > 90%<br />

B) The accuracy must be between 81% and 88%<br />

C) The accuracy must be between 84% and 90%<br />

D) The accuracy must be < 81%<br />

E) The accuracy must be between 84% and 88%


Q&A: Test Validation<br />

ANSWERS


Statistical Validation


Q26: Foundational Answer<br />

With respect to statistical test validation and classification of test results<br />

as true positive, false positive, true negative, or false negative, the<br />

assumption is that<br />

A) the gold standard, although not perfect, is good enough.<br />

B) that the test is not as good as the gold standard.<br />

C) that the gold standard is perfect.<br />

D) that the gold standard is not as good as the test.<br />

E) There are more false results than true results.


Q27: Answer<br />

Scary hospital vascular lab is validating their testing procedure predicting<br />

common carotid artery disease. The following results were obtained relative to<br />

the “gold standard”:<br />

‣ For the 71 times the test predicted disease, the test matched the gold<br />

standard 51 times.<br />

‣ For the 179 times the test predicted no disease, the test matched the gold<br />

standard 160 times<br />

Of the patients who were tested, how many have disease<br />

A) 160<br />

B) 71<br />

C) 70<br />

D) 51<br />

E) 20<br />

Comparison Test<br />

+<br />

_<br />

(TP)<br />

Gold Standard<br />

_<br />

+<br />

51<br />

(FN)<br />

19<br />

(FP)<br />

20<br />

(TN)<br />

160


Q28: Answer<br />

For this test, statistically which is most likely<br />

A) Claim that a patient does not have disease when they do -- (SENSITIVITY)<br />

B) To be incorrect when positive for disease -- (PPV)<br />

C) Claim that a patient has disease when they do not – (SPECIFICITY)<br />

D) To be incorrect when negative for disease -- (NPV)<br />

Gold Standard<br />

_<br />

+<br />

Comparison Test<br />

+<br />

_<br />

(TP)<br />

51<br />

(FN)<br />

19<br />

(FP)<br />

20<br />

(TN)<br />

160


Q29: Answer<br />

For a given test, the PPV is 81% the NPV is 88%, the sensitivity is 84%<br />

and the specificity is 90%, which statement is true regarding the overall<br />

accuracy.<br />

A) The accuracy must be > 90%<br />

B) The accuracy must be between 81% and 88%<br />

C) The accuracy must be between 84% and 90%<br />

D) The accuracy must be < 81%<br />

E) The accuracy must be between 84% and 88%


PREPARING FOR THE <strong>RPVI</strong> EXAM<br />

<strong>RPVI</strong> eCourses<br />

<strong>RPVI</strong> <strong>Exam</strong> Sims<br />

Go Online: SVU, SVS, or www.PegasusLectures.com


<strong>RPVI</strong> eCourse (Modules)


<strong>RPVI</strong> <strong>Exam</strong> Sims


END REVIEW<br />

Frank R. Miele<br />

President and Founder<br />

Pegasus Lectures, Inc.<br />

FMiele@PegasusLectures.com

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