Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
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<strong>IL</strong>-<strong>23</strong> promoting cellular immunity<br />
its production in hematopoietic cells is critical.<br />
its biological <strong>activity</strong> requires cell-specific expression<br />
Its important in indirectly control <strong>of</strong> infections<br />
<strong>IL</strong>-<strong>23</strong> modulates DC costimulatory function<br />
pathways <strong>of</strong> <strong>IL</strong>-12 <strong>and</strong> <strong>IL</strong>-<strong>23</strong> are very similar<br />
<strong>IL</strong>-<strong>23</strong>could act to down-regulate Stat4-dependent actions <strong>of</strong> <strong>IL</strong>-12<br />
unique role for <strong>IL</strong>-<strong>23</strong> in promoting cellular immune responses<br />
Watford, W. T., et al. 2004. Signaling by <strong>IL</strong>-12 <strong>and</strong> <strong>IL</strong>-<strong>23</strong> <strong>and</strong> the immunoregulatory roles <strong>of</strong> STAT4. Immunol. Rev. 202: 139–156.<br />
Lankford, C. S. R. <strong>and</strong> Frucht, D. M., A unique role for <strong>IL</strong>-<strong>23</strong> in promoting cellular immunity. J. Leukoc. Biol. 2003. 73: 49–56.
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