Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
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Autoimmune myocardits: <strong>IL</strong><strong>17</strong>-<br />
VLP vaccination<br />
<strong>IL</strong>-12 p35 KO <strong>and</strong> WT mice developed myocarditis<br />
p40 KO mice show low level <strong>of</strong> disease.<br />
Injection <strong>of</strong> anti-p19 antibody reduced the disease<br />
Sonderegger, I. et al., Neutralization <strong>of</strong> <strong>IL</strong>-<strong>17</strong> by active vaccination inhibits <strong>IL</strong>-<strong>23</strong>-mediated autoimmune myocarditis. Eur. J. Immunol.<br />
2006. 36: DOI: 10.1002/eji.200636484
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