Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17 Biological activity of IL 23 and IL 17
IL 17 in diseases: in tumorigenesis IL-17 inhibited the growth of hematopoietic tumors (mastocytoma P815 and lymphoma J558L in immunocompetent mice Benchetrit F, et al., Tartour E: Interleukin-17 inhibits tumor cell growth by means of a T-cell- dependent mechanism. Blood 2002, 99.
IL-17 in tumorigenesis: conclusion IL-17 is pleiotropic a cytokine with opposite activities in the regulation of tumor growth increased growth in nude mice Inhibition of immunogenic tumors in immunocompetent mice by T-cell-dependent mechanism Other cytokines have this feature These antagonistic activities of cytokines in the regulation of tumor growth, which often depends on the immunogenicity of the tumor model, must be taken into consideration when these molecules are used in trials of immunotherapy.
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- Page 3 and 4: IL-23
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- Page 7 and 8: IL 17
- Page 9 and 10: The IL-17 super family Pleiotropic
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- Page 15: IL 17 in diseases: in tumorigenesis
- Page 19 and 20: Autoimmune myocardits: IL17- VLP va
- Page 21 and 22: auto-immune encephalomyelitis IL- 1
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<strong>IL</strong> <strong>17</strong> in diseases: in tumorigenesis<br />
<strong>IL</strong>-<strong>17</strong> inhibited the growth <strong>of</strong> hematopoietic tumors (mastocytoma<br />
P815 <strong>and</strong> lymphoma J558L in immunocompetent mice<br />
Benchetrit F, et al., Tartour E: Interleukin-<strong>17</strong> inhibits tumor cell growth by means <strong>of</strong> a T-cell- dependent mechanism. Blood 2002, 99.
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