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Biological activity of IL 23 and IL 17

Biological activity of IL 23 and IL 17

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<strong>IL</strong> <strong>17</strong> in diseases:<br />

<strong>IL</strong>-<strong>17</strong> in other diseases<br />

Possible pathogenic role in viral infections<br />

(tropic Herpes virus saimiri)<br />

Elevated levels in bacterial infections<br />

Important role in immune response in the lung<br />

•Patera AC, et al. : Interleukin <strong>17</strong> modulates the immune response to vaccinia virus infection. Virology 2002, 299:56-63.<br />

• Linden A, Adachi M: Neutrophilic airway inflammation <strong>and</strong> <strong>IL</strong>- <strong>17</strong>. Allergy 2002, 57:769-775.<br />

•Sarah L Gaffen, Biology <strong>of</strong> recently discovered cytokines: Interleukin-<strong>17</strong> – a unique inflammatory cytokine with roles in bone biology<br />

<strong>and</strong> arthritis, Arthritis Res Ther 2004, 6:240-247

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