Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
Biological activity of IL 23 and IL 17
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<strong>IL</strong> <strong>17</strong> in diseases:<br />
RA, CIA <strong>and</strong> EAE<br />
In RA <strong>IL</strong>-<strong>17</strong> is upregulated in early disease<br />
<strong>IL</strong>-<strong>17</strong> knockout mice are resistant to CIA<br />
Development <strong>of</strong> EAE is reduced in <strong>IL</strong>-<strong>17</strong> knockout mice<br />
Lubberts, E., et al. 2005. The role <strong>of</strong> T cell interleukin-<strong>17</strong> in conducting destructive arthritis: lessons from animal models. Arthritis<br />
Res. Ther. 7: 29–37.<br />
Komiyama, Y. Et al., <strong>IL</strong>-<strong>17</strong> plays an important role in the development <strong>of</strong> experimental autoimmune encephalomyelitis. J. Immunol.<br />
2006. <strong>17</strong>7: 566–573.
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