Guidelines on Diagnosis and Treatment of Malignant Lymphomas
Guidelines on Diagnosis and Treatment of Malignant Lymphomas
Guidelines on Diagnosis and Treatment of Malignant Lymphomas
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
Splenic Marginal<br />
Z<strong>on</strong>e Lymphoma<br />
Definiti<strong>on</strong> <strong>and</strong> Incidence<br />
SMZL is an indolent B-cell lymphoma usually involving spleen,<br />
b<strong>on</strong>e marrow <strong>and</strong> blood. Patients usually present with<br />
splenomegaly <strong>and</strong>/or anaemia. Splenic hilar lymph nodes may be<br />
involved, although other lymphadenopathy is rare. B<strong>on</strong>e marrow<br />
<strong>and</strong> peripheral blood involvement is comm<strong>on</strong>. The disease is rare,<br />
comprising