Guidelines on Diagnosis and Treatment of Malignant Lymphomas
Guidelines on Diagnosis and Treatment of Malignant Lymphomas
Guidelines on Diagnosis and Treatment of Malignant Lymphomas
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Nodular/Follicular pattern<br />
a. Nodular/follicular pattern with small cell morphology<br />
Follicular Lymphoma<br />
Mantle Cell Lymphoma<br />
Marginal Z<strong>on</strong>e Lymphoma<br />
SLL/CLL<br />
BASIC IHC PANEL ON FFPET<br />
CD20<br />
CD3<br />
CD5<br />
CD10<br />
CD23<br />
Cyclin D1<br />
BCL 2<br />
Ki67<br />
FCM<br />
Cytogenetics<br />
b. Nodular/follicular pattern with larger cells or “atypical” morphology c<strong>on</strong>sider -<br />
NLPHL<br />
Lymphocyte Rich HL<br />
NSHL<br />
And h<strong>and</strong>le as per HL<br />
c. N<strong>on</strong>-nodular small cell morphology<br />
Investigate as per basic IHC panel<br />
C<strong>on</strong>sider Lymphoplasmacytic lymphoma<br />
Potential diagnostic pitfalls for small cell morphology<br />
■<br />
Lymphoplasmacytic lesi<strong>on</strong>s<br />
11