APPLICANT - Imperial College London

the context of ischaemic heart disease. Our particular interest is in clinical and experimental
studies of adaptation to ischaemia through the growth of coronary collaterals and myocardial
conditioning. We investigate collaterals and conditioning using the whole range of basic and
clinical laboratory techniques as well as advanced imaging with MRI. The Research theme
lies in the Cardiovascular Division on the St Thomas' Hospital Campus and involves an
interdisciplinary group of clinicians and scientists based in the Rayne Institute. The other
relevant investigators working with Michael Marber in the Rayne Institute include Simon
Redwood, Metin Avkiran, Michael Shattock, Phil Eaton, Jon Kentish, Mike Curtis, Reza
Razavi, Eike Nagel and Rene Botnar. The associated F2 clinical attachments will be A&E
and General Internal Medicine (Cardiology).
Post 18 – Nephrology (Professor R Lechler/Professor S Sacks) – based at GSTT
CODE: KCL/018
F1
F2
See rotation
for site
Guy’s and
St
Thomas’s
NHS
Foundation
Trust
Renal Medicine
(St Thomas’
Hospital)
Nephrology
(Academic
Attachment)
3m
4m
General
Surgery
(St Thomas'
Hospital)
Accident &
Emergency
3m
4m
Acute
Medicine
(St Thomas’
Hospital)
General
Surgery
(Vascular)
3m
4m
Infectious
Diseases
(St
Thomas’s
Hospital)
3m
The KCL Department of Nephrology and Transplantation is part of the Division of
Immunobiology, Infection and Inflammatory Disease (DIIID). It has over 40 active research
staff. The department is at the centre of the recently awarded MRC centre in
Transplantation at KCL. The Department has programme level funding from the MRC and
project grant support from the Wellcome Trust, Clinical Research Training Fellowships from
the MRC and BHF and Wellcome, Studentships from the MRC and other charitable and
industry funding. There are close links with other research areas including Human Genetics,
Imaging Science, Stem Cell Technology and Medical Law and Ethics. These links are
developing within both the MRC centre in transplantation and the NIHR centre. A new
Clinical Research Centre is being built on the Guy’s site and will be matched with a similar
unit on the St Thomas’s site. This will be the basis for increased translational research
activity. The Department head and MRC centre director is Professor Steven Sacks. There
are four other clinically qualified principal investigators (Lord, Lechler, Wong, Robson) and
seven non-clinical PIs (Lombardi, Zhou, Vaughan, Jurcovic, Kemper, Martín-Fontecha,
Smith). The research interests include both transplantation (Complement and the innate
immune system in transplantation, dendritic cell function, T regulatory cells and the
development of tolerance, T cell transcription control and genetic factors influencing
transplant outcome) and nephrology (immune mechanisms of glomerular injury, local
complement synthesis in the kidney and immune functions in progressive fibrosis). The
trainee will undertake a research programme in one of those areas. The associated F2
clinical attachments will be A&E and General Surgery (Vascular).
Post 19 – Psychological Medicine and Psychiatry (Professor S Wessely) – based
at KCH/ GSTT/SLAM
CODE: KCL/019
F1
F2
See rotation
for site
Guy’s and
St Thomas’
NHS
Foundation
Trust
General
Medicine
(St Thomas’
Hospital)
Psychiatry
(Academic
Attachment)
3m Anaesthetics /
Perioperative(
St Thomas’
Hospital)
4m
Accident &
Emergency
3m
4m
General
Surgery
(Lower GI)
(St Thomas’
Hospital)
General
Medicine
3m
4m
Urology
(Guy’
Hospital)
3m
www.stfs.org.uk/student/academic-programmes
Email: tfsacademicrecruitment@stfs.org.uk
Page 53 of 70
Updated: 27 May 2010