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APPLICANT - Imperial College London

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CODE: KCL/009<br />

F1<br />

F2<br />

See rotation<br />

for site<br />

Guy’s and<br />

St Thomas’<br />

NHS<br />

Foundation<br />

Trust<br />

General<br />

Medicine (St<br />

Thomas’<br />

Hospital)<br />

3m<br />

Elderly Care<br />

(St Thomas’<br />

Hospital)<br />

Haematology 4m General<br />

Medicine<br />

3m<br />

4m<br />

Orthopaedics<br />

(Guy’s<br />

Hospital)<br />

Pharmacology<br />

(Academic<br />

Attachment)<br />

3m<br />

4m<br />

General<br />

Surgery<br />

(Vasc) (St<br />

Thomas’<br />

Hospital)<br />

3m<br />

Guy’s Drug Research Unit (GDRU) now Quintiles Drug Research Unit at Guy’s Hospital<br />

evolved from the interaction of academics at Guy’s Hospital Medical School and the<br />

Pharmaceutical Industry working together in early drug development. The Unit has<br />

investigated over 300 new small molecules and biologics in man. Quintiles Drug Research<br />

Unit has a 75 bed unit adjacent to the Hodgkin Building at the Guy’s site of King’s <strong>College</strong>,<br />

<strong>London</strong> and a 35 bed unit on the 14 th floor of the Tower Wing also on the Guy’s site. In 1995<br />

GDRU was acquired by Quintiles, the leading international contract research organisation.<br />

Founded in 1982 by Dennis Gillings, a British biostatistician then based at the University of<br />

North Carolina, Quintiles now has approximately 20,000 employees and has offices in more<br />

than 50 countries. Quintiles has helped develop or commercialise every one of the world’s<br />

top 30 best selling drugs. Training and experience will be available in exploratory, early<br />

phase drug development, tailored to suit the trainee. Most of the training offered will be<br />

available on the Guy’s site: subjects may include management principles and skills, good<br />

clinical practise, communication skills, computer skills, assisting in writing informed consent<br />

documents and Ethics Committee applications, conducting and writing up a personal<br />

research project and the place of research and higher degrees in training for clinical<br />

careers. The senior medical staff are Professor Tim Mant, Dr Darren Wilbraham, Dr<br />

Marianne Kasti and Professor James Ritter. The associated F2 clinical attachments will be<br />

Haematology and General Medicine (Respiratory).<br />

Post 10 – Asthma, Allergy and Respiratory Medicine (Professor T Lee) – based at<br />

GSTT<br />

CODE: KCL/010<br />

F1<br />

F2<br />

St Thomas’<br />

Hospital<br />

Guy’s and<br />

St Thomas’<br />

NHS<br />

Foundation<br />

Trust<br />

Trauma &<br />

Orthopaedics<br />

Accident &<br />

Emergency<br />

3m<br />

4m<br />

General<br />

Surgery<br />

(Lower GI)<br />

Allergy/<br />

Respiratory<br />

Medicine<br />

3m Rheumatology 3m General<br />

Medicine<br />

4m GUM 4m<br />

3m<br />

The post will be based within the Division of AALB in KCL, which has very close links with<br />

the Allergy and Respiratory Medicine NHS Services at Guy's & St Thomas' NHS Foundation<br />

Trust. The Divisional research programmes are internationally competitive. In 2005 the MRC<br />

awarded funds to establish a MRC-Asthma UK Centre in Allergic Mechanisms of Asthma at<br />

KCL in partnership with Asthma UK, <strong>Imperial</strong> <strong>College</strong> and associated NHS Trusts. Divisional<br />

research programmes are supported by three current programme grants (one from MRC,<br />

one from Wellcome Trust and one from NIHR); grants from the Immune Tolerance Network;<br />

and Food Standards Agency. The total value of research awards in the Division is c. £31.4m.<br />

Broad research areas covered include IgE structure, function and regulation; airways<br />

inflammation and remodelling; prevention and therapy of allergy, asthma and chronic<br />

respiratory morbidity; tight junction biology; the EFGR network in normal airway epithelium<br />

and lung cancer; and Endobronchial Ultrasound in the diagnosis and management of<br />

Thoracic Diseases. The clinical/basic science interface is key to the Division’s success.<br />

Close interactions between non-clinical and clinical scientists provide improved opportunities<br />

for new ideas to arise and for discoveries from gene to bedside to be fully exploited for the<br />

www.stfs.org.uk/student/academic-programmes<br />

Email: tfsacademicrecruitment@stfs.org.uk<br />

Page 49 of 70<br />

Updated: 27 May 2010

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