APPLICANT - Imperial College London

The project will involve an aspect of immune profiling (candidate gene quantitative PCR) in a
selected cohort of transplant patients. The associated F2 clinical attachments will be A&E
and Hepatology.
Post 4 – Cardiovascular (Professor A Shah) – based at KCH
CODE: KCL/004
F1
F2
King’s
College
Hospital
King’s
College
Hospital
General
Medicine
3m
General
Medicine
A&E 4m Cardiology
(Academic
Attachment)
3m Cardiology 3m General
Surgery
4m
Cardiology
(Clinical
Attachment)
4m
3m
The KCL Cardiovascular Division comprises 35 PIs and >50 PhD/MD students among a total
of ~ 160 staff, and has been designated as a British Heart Foundation Centre of Excellence,
one of only 4 such centres nationally. The overall goal of research activities is to pursue
laboratory-to-bedside research programmes that address fundamental molecular, cellular
and physiological mechanisms underlying normal and abnormal cardiovascular function, and
to link these to translational research that improves the prevention, diagnosis and treatment
of human cardiovascular disease. The Division undertakes high-quality non-clinical and
clinical research training, including a BHF 4-year PhD training programme. The research
attachment will be based within the James Black Centre, a state-of-the-art institute that
provides excellent research facilities and infrastructure. A wide range of cardiac and vascular
biomedical areas are studied including cardiac hypertrophy, heart failure, endothelial
dysfunction, vascular aging, atherosclerosis and stem cells. Senior investigators working
alongside Ajay Shah in the James Black Centre include Cathy Shanahan, Qingbo Xu,
Manuel Mayr, Alex Ivetic and Alison Brewer. It may be feasible to continue some work on the
research project during the clinical attachment. The associated F2 clinical attachments will
be A&E and Cardiology at KCH. For further details on the Cardiovascular Division and BHF
Centre, visit http://www.kcl.ac.uk/schools/medicine/research/cardio/.
Post 5 – Haematology (Professor S L Thein) – based at KCH
Code: KCL/005
F1
F2
King’s
College
Hospital
King’s
College
Hospital
General
Medicine
Haematology
(Clinical
Attachment)
3m Haematology 3m General
Surgery
4m A&E 4m Haematology
(Academic
Attachment)
3m
4m
General
Medicine
3m
The four-month clinical attachment will be based in the Department of Haematological
Medicine (Head of Department – Professor G Mufti). It will provide exposure to a broad
spectrum of the different sub-specialities; red cell and Paediatric haematology, including
sickle cell disease and other haemoglobinopathies, and genetic counselling of these
disorders (Professor S L Thein, Drs David Rees, Moji Awogbade, and Sue Height);
haemato-oncology and bone marrow failure (Professors G Mufti and Judith Marsh, Drs
Tony Pagliuca, Steve Schey, Steve Devereux, Al Ho and Dupe Elubute); thrombosis and
haemostasis (Drs Roopen Arya and Raj Patel), and blood transfusion (Dr Alek Mijovic). It is
envisaged that the trainee spends one month in each of the four sub-specialities, during
which s/he will attend the relevant consultant-led clinics, speciality ward rounds and clinical
meetings, in addition to the weekly departmental seminars, joint X-ray and joint
histopathology meetings. Each sub-speciality will have its own time-table of meetings and
clinics. There is no on-call or out-of-hours commitment in this post but it is expected that the
trainee will be able to be flexible about hours to encompass the demands of research taken.
The research/laboratory attachment will be with Professor Thein’s red cell haematology
group within the Division of Gene and Cell Based Therapy (Head, Professor S L Thein) or
any of the other haematology sub-groups. Haematology research laboratories are based in
the James Black Centre and the Rayne Institute which are equipped with state-of-the-art
www.stfs.org.uk/student/academic-programmes
Email: tfsacademicrecruitment@stfs.org.uk
Page 47 of 70
Updated: 27 May 2010