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VAP prevention – non-antimicrobial methods

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The UK TracMan trial<br />

N=909 Early (Day1-4) Late (>10 days)<br />

30d mortality 30.8% 31.5%<br />

ICU LOS 13 13<br />

Hosp LOS 33 34<br />

Antibiotic use<br />

• Identical<br />

Sedation<br />

• Lower in early arm<br />

• Mean 6.9 vs. 9.3 days<br />

54% of ‘late’ arm (wait & see arm) never needed a<br />

tracheostomy!

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