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VAP prevention – non-antimicrobial methods

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Pneumonia in intubated patients: role of respiratory<br />

airway care.<br />

Rello J et al, Am J Respir Crit Care Med 1996; 154: 111-5<br />

• 83 consecutive intubated patients undergoing continuous<br />

aspiration of subglottic secretions (CASS)<br />

• Failure of CASS (RR = 7.5, 95% CI = 1.5-38) & persistent<br />

intracuff pressure below 20 cm H 2 O (RR = 4.2, CI = 1.1-16)<br />

were factors independently associated with <strong>VAP</strong><br />

• Colonized subglottic secretions around the cuff are the<br />

most important risk factor for <strong>VAP</strong> in the 1 st 8 days of<br />

intubation<br />

• Study confirmed the importance of maintaining adequate<br />

cuff pressure & effective subglottic aspiration to prevent<br />

pneumonia

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