VAP prevention â non-antimicrobial methods
VAP prevention â non-antimicrobial methods
VAP prevention â non-antimicrobial methods
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Oropharyngeal cleansing with 0.2% chlorhexidine for<br />
<strong>prevention</strong> of pneumonia in critically ill patients: a<br />
randomized trial.<br />
Panchabhai TS et al, Chest 2009; 135: 1150-6<br />
• CHX 0.2% vs. 0.1% potassium permanganate applied BD in<br />
471 patients<br />
0.2% CHX<br />
N=224<br />
Control<br />
N=247<br />
P Value<br />
<strong>VAP</strong> incidence 16 (7.1%) 19 (7.7%) NS<br />
Day of development of<br />
pneumonia (median)<br />
5 5 NS<br />
• No difference in any other outcome measured<br />
What about higher concentrations used more frequently…