06.01.2015 Views

2011 ASH Program Book - American Society of Hypertension

2011 ASH Program Book - American Society of Hypertension

2011 ASH Program Book - American Society of Hypertension

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc.<br />

<strong>2011</strong> Annual Scientific Meeting<br />

and Exposition<br />

<strong>Program</strong> <strong>Book</strong><br />

Hilton New York<br />

Saturday, May 21, <strong>2011</strong> – Tuesday, May 24, <strong>2011</strong>


8More than<br />

References: 1. Pepine CJ, Handberg EM, Cooper-DeH<strong>of</strong>f RM, et al; INVEST Investigators. A calcium<br />

antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery<br />

disease. The International Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. JAMA.<br />

2003;290(21):2805-2816. 2. Dahlöf B, Sever PS, Poulter NR, et al; ASCOT Investigators. Prevention<br />

<strong>of</strong> cardiovascular events with an antihypertensive regimen <strong>of</strong> amlodipine adding perindopril as required<br />

versus atenolol adding bendr<strong>of</strong>lumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes<br />

Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet.<br />

2005;366(9489):895-906. 3. Black HR, Elliott WJ, Grandits G, et al; CONVINCE Research Group. Principal<br />

results <strong>of</strong> the Controlled Onset Verapamil Investigation <strong>of</strong> Cardiovascular End Points (CONVINCE) trial. JAMA.<br />

2003;289(16):2073-2082. 4. Dahlöf B, Devereux RB, Kjeldsen SE, et al; LIFE Study Group. Cardiovascular<br />

morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a<br />

randomised trial against atenolol. Lancet. 2002;359(9311):995-1003.<br />

Novartis Pharmaceuticals Corporation<br />

East Hanover, New Jersey 07936<br />

©<strong>2011</strong> Novartis


Visit booth<br />

#1100<br />

to find out more<br />

out <strong>of</strong><br />

10<br />

patients may need more than<br />

1 agent to get to BP goal 1-4<br />

Printed in USA 4/11 DIO-1052602


About the <strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>, Inc.<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc., (<strong>ASH</strong>) is the largest<br />

organization <strong>of</strong> hypertension researchers and health care providers<br />

in the United States committed to eliminating hypertension and its<br />

consequences. <strong>ASH</strong> has a domestic and international membership <strong>of</strong><br />

basic science and clinical investigators, physicians, physician assistants,<br />

nurse practitioners and pharmacists, as well as other individuals<br />

with a scientific interest in hypertension.<br />

The <strong>Society</strong> was founded in 1985 in order to provide a forum for the<br />

exchange <strong>of</strong> information among basic scientists, clinical investigators<br />

and others involved in the study or management <strong>of</strong> high blood pressure.<br />

The specific focus <strong>of</strong> the <strong>Society</strong> is to translate current research<br />

findings in hypertension into effective treatment strategies, in order<br />

to better address the needs <strong>of</strong> hypertensive patients. The primary mission<br />

<strong>of</strong> the <strong>Society</strong> is to improve the care <strong>of</strong> patients with hypertension<br />

and associated disorders by:<br />

• Enhancing the education and treatment <strong>of</strong> patients with hypertension<br />

• Educating health care pr<strong>of</strong>essionals regarding hypertension and<br />

current prevention and treatment strategies<br />

• Assisting health care pr<strong>of</strong>essionals in addressing the challenges <strong>of</strong><br />

the modern-day care <strong>of</strong> patients with hypertension<br />

• Advocating public policy that ensures patient access to high<br />

quality hypertension care and supports increased hypertension<br />

research<br />

• Facilitating communication and collaboration among providers,<br />

investigators, policymakers, and patients in areas relating to hypertension<br />

and vascular health<br />

• Promoting the career development <strong>of</strong> researchers in hypertension<br />

and associated disorders, including research in the pathobiology,<br />

prevention, diagnosis, treatment, and psychosocial aspects <strong>of</strong><br />

hypertension<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. is an accredited provider<br />

<strong>of</strong> Continuing Medical Education (CME) by the Accreditation Council<br />

for Continuing Medical Education (ACCME) to sponsor continuing<br />

medical education for physicians.<br />

For more information contact the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>,<br />

Inc. at:<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc.<br />

148 Madison Avenue<br />

Fifth Floor<br />

New York, NY 10016<br />

Telephone: 212-696-9099<br />

Fax: 212-696-0711<br />

E-mail: ash@ash-us.org<br />

Website: www.ash-us.org


Past Presidents <strong>of</strong> the <strong>American</strong><br />

<strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc.<br />

John H. Laragh, MD<br />

First President<br />

Edward G. Biglieri, MD President 1988 – 1990<br />

Jay N. Cohn, MD President 1990 – 1992<br />

Louis Tobian, MD President 1992 – 1994<br />

Barry M. Brenner, MD President 1994 – 1995<br />

Lawrence R. Krak<strong>of</strong>f, MD President 1995 – 1996<br />

Michael H. Alderman, MD President 1996 – 1998<br />

Michael A. Weber, MD President 1998 – 2000<br />

Theodore W. Kurtz, MD President 2000 – 2002<br />

Haralambos Gavras, MD President 2002 – 2004<br />

Thomas D. Giles, MD President 2004 – 2006<br />

Jean E. Sealey, DSC President May 19, 2006<br />

Suzanne Oparil, MD President 2006 – 2008<br />

Henry R. Black, MD President 2008 – 2010


Table <strong>of</strong> Contents<br />

General Information.................................................................... 9<br />

Continuing Education................................................................ 9<br />

Hilton New York Floor Layout................................................ 10<br />

Corporate Members.................................................................... 16<br />

Meeting Sponsors........................................................................ 17<br />

<strong>ASH</strong> Leadership.............................................................................. 18<br />

<strong>2011</strong> <strong>Program</strong> Committee....................................................... 19<br />

Robert Tigerstedt Award Lecture........................................ 20<br />

Young Scholar Award Lectures............................................ 22<br />

Marvin Moser Clinical <strong>Hypertension</strong><br />

Award Lecture................................................................................. 24<br />

<strong>2011</strong> Abstract Reviewers.......................................................... 26<br />

Poster Category Presentation by Day .............................. 30<br />

<strong>ASH</strong> Faculty....................................................................................... 32<br />

<strong>Program</strong> at a Glance.................................................................... 35<br />

<strong>Hypertension</strong> Highlights <strong>2011</strong>, May 21........................... 40<br />

<strong>ASH</strong> <strong>Program</strong>, May 21................................................................. 41<br />

Primary Care Clinician <strong>Program</strong>, May 22......................... 49<br />

<strong>ASH</strong> <strong>Program</strong>, May 22................................................................. 51<br />

<strong>ASH</strong> <strong>Program</strong>, May 23................................................................. 64<br />

<strong>ASH</strong> <strong>Program</strong>, May 24................................................................. 78<br />

<strong>ASH</strong> <strong>Program</strong> Posters, May 21............................................... 86<br />

<strong>ASH</strong> <strong>Program</strong> Posters, May 22............................................... 104<br />

<strong>ASH</strong> <strong>Program</strong> Posters, May 23............................................... 125<br />

<strong>ASH</strong> <strong>Program</strong> Late-Breaking Posters, May 23.............. 144<br />

Faculty Disclosure Listing......................................................... 145<br />

<strong>ASH</strong> Exhibitor Floor Plan........................................................... 154<br />

<strong>ASH</strong> Innovations Theater.......................................................... 157<br />

<strong>ASH</strong> Exhibitors ................................................................................ 158<br />

Author Index.................................................................................... 168<br />

Hilton New York Floor Plans................................................... 181<br />

5


<strong>Program</strong> Color Key<br />

The pages <strong>of</strong> this <strong>Program</strong> <strong>Book</strong> are color-coded to match the<br />

<strong>Program</strong> at a Glance (pages 35–36) and serve as a quick, identifiable<br />

reference <strong>of</strong> the type <strong>of</strong> educational activity or event taking place.<br />

Scientific Sessions*<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

<strong>Hypertension</strong> Highlights <strong>2011</strong><br />

Special Event<br />

Meet the Pr<strong>of</strong>essor Sessions<br />

<strong>Hypertension</strong> for the Primary Care Clinician<br />

Debates<br />

Poster Sessions<br />

Satellite Symposia<br />

<strong>Hypertension</strong> Resource Pavilion<br />

The <strong>ASH</strong> Twenth-Sixth Annual Scientific Meeting is<br />

organized around three (3) concurrent themes:<br />

• Pathobiology <strong>of</strong> <strong>Hypertension</strong><br />

• Translational Issues in <strong>Hypertension</strong><br />

• Therapy <strong>of</strong> <strong>Hypertension</strong><br />

Sessions in each <strong>of</strong> the three (3) themes (or tracks) are labeled<br />

throughout the <strong>Program</strong> <strong>Book</strong> to be easily identifiable.<br />

Future Meeting Dates<br />

Saturday, May 19, 2012 to Tuesday, May 22, 2012<br />

Hilton New York, New York, NY<br />

Wednesday, May 15, 2013 to Saturday, May 18, 2013<br />

San Francisco Marriott, San Francisco, CA


Letter from the President<br />

and <strong>Program</strong> Committee Chair<br />

Dear Colleague,<br />

On behalf <strong>of</strong> the Board <strong>of</strong> Directors <strong>of</strong> the<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc.<br />

(<strong>ASH</strong>), we are pleased to welcome you to<br />

the Twenty-Sixth Annual Scientific Meeting<br />

and Exposition <strong>of</strong> <strong>ASH</strong>. The theme <strong>of</strong><br />

this year’s Scientific Meeting is Adolescent<br />

Obesity and Cardiovascular Risk Reduction:<br />

The Expanding Epidemic.<br />

The <strong>2011</strong> Annual Scientific meeting topics<br />

are organized around three (3) concurrent<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

themes:<br />

— Pathobiology <strong>of</strong> <strong>Hypertension</strong><br />

— Translational Issues in <strong>Hypertension</strong><br />

— Therapy <strong>of</strong> <strong>Hypertension</strong><br />

The Scientific Sessions feature several innovative<br />

components designed to enhance the<br />

translation <strong>of</strong> basic and applied research<br />

into effective hypertension prevention and<br />

treatment strategies.<br />

• <strong>Hypertension</strong> Highlights <strong>2011</strong> –<br />

Saturday, May 21, <strong>2011</strong><br />

<strong>Hypertension</strong> Highlights is a full-day William B. White, MD, F<strong>ASH</strong><br />

program dedicated to educating clinicians<br />

and scientists about some <strong>of</strong> the most interesting, controversial<br />

and evolving topics in the field. It is an ideal update for<br />

<strong>Hypertension</strong> Specialists and those wishing to become specialists<br />

in the field.<br />

• Plenary Session I – Sunday, May 22, <strong>2011</strong><br />

The Keynote speaker for the opening session will be F. Xavier<br />

Pi-Sunyer, MD, MPH, Pr<strong>of</strong>essor <strong>of</strong> Medicine, Chief <strong>of</strong> Endocrinology,<br />

Diabetes, and Nutrition, Director <strong>of</strong> the New York Obesity<br />

Research Center, St. Luke’s/Roosevelt Hospital Center, New York,<br />

New York. Dr. Pi-Sunyer will speak on “Blood Pressure in Obesity.”<br />

Following Dr. Pi-Sunyer’s lecture will be Dr. Rae-Ellen Kavey<br />

presenting a lecture on “Cardiovascular Risk and Risk Reduction<br />

in Children and Adolescents,” Dr. Sadaf Farooqi, PhD, presenting a<br />

lecture on “Mechanisms from Studies <strong>of</strong> Human Obesity” and Dr.<br />

Joseph Flynn addressing the topic <strong>of</strong> “Evaluation and Treatment <strong>of</strong><br />

<strong>Hypertension</strong> in Childhood.”<br />

• Plenary Session II – Monday, May 23, <strong>2011</strong><br />

This session will include the Awards Session as well as state-<strong>of</strong>-theart<br />

topics. Dr. Oscar Carretero will present the Robert Tigerstedt<br />

Award Lecture on “Acetyl-Ser-Asp-Lys-Pro, an Endogenous Tetrapeptide:<br />

Role in Target Organ Damage in <strong>Hypertension</strong>, and Autoimmune<br />

Myocarditis.” Young Scholar Awards will be presented to<br />

Drs. Michael Ryan and Alessandro Cataliotti. Dr. Murray Epstein<br />

will receive the Marvin Moser Clinical <strong>Hypertension</strong> Award.<br />

7


Letter continued<br />

Following the Awards Session, Dr. Abraham Aviv will present a<br />

lecture on the “Leukocyte Telomere Length Genetics and Cardiovascular<br />

Disease” and Dr. Joseph Hill will discuss “Development <strong>of</strong><br />

Cardiac Hypertrophy.”<br />

• Young Investigator-in-Training Abstract Competition<br />

Saturday, May 21, <strong>2011</strong><br />

Trainees submitting the highest ranking abstracts to the meeting<br />

will present their work orally in a special session and compete for<br />

cash prizes. This highlighted session is consistent with <strong>ASH</strong>’s goal<br />

to foster and facilitate the training <strong>of</strong> young and new investigators<br />

in hypertension.<br />

• <strong>Hypertension</strong> for the Primary Care Clinician –<br />

Sunday, May 22, <strong>2011</strong><br />

This program will address commonplace questions that face clinicians<br />

in day-to-day care <strong>of</strong> hypertension including peri-operative<br />

hypertension management, clinical partners in ambulatory care<br />

management <strong>of</strong> hypertension and the resistant hypertensive<br />

patient.<br />

• Debates – Saturday, May 21 – Sunday, May 22, <strong>2011</strong><br />

This year there are five debates on controversial topics <strong>of</strong> relevance<br />

to <strong>Hypertension</strong> Specialists.<br />

• Joint <strong>Society</strong> Symposia<br />

Interactions with other societies, both national and international,<br />

focused on the topic <strong>of</strong> hypertension and cardiovascular and<br />

kidney disease risk as it relates to obesity will be covered. This year<br />

we have a record number <strong>of</strong> joint society sessions that include:<br />

AHA Council for High Blood Pressure Research (HBPR), the<br />

Association for Research into Arterial Structure and Physiology<br />

(ARTERY), the China Social Worker’s Association Vascular Protection<br />

Committee, the European <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> (ESH),<br />

<strong>Hypertension</strong> Canada, the International Pediatric <strong>Hypertension</strong><br />

Association (IPHA), the International <strong>Society</strong> on <strong>Hypertension</strong><br />

in Blacks (ISHIB), the Inter-<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong><br />

(I<strong>ASH</strong>), the National Lipid Association/<strong>American</strong> <strong>Society</strong><br />

for Preventive Cardiology (NLA/ASPC), the National Kidney<br />

Foundation (NKF) and the Preventive Cardiovascular Nurses<br />

Association (PCNA).<br />

The <strong>Society</strong> will also sponsor a small number <strong>of</strong> industry-supported<br />

Satellite Symposia which will introduce novel approaches to antihypertensive<br />

therapy. The Pavilion will host many informative scientific,<br />

technical, periodical and book exhibits designed to support you in<br />

your mission <strong>of</strong> providing the latest in care for your hypertensive<br />

patients.<br />

We look forward to seeing you in New York.<br />

Sincerely,<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

President, 2010 – 2012<br />

William B. White, MD, F<strong>ASH</strong><br />

Chair, <strong>2011</strong> Scientific <strong>Program</strong><br />

Committee<br />

8


General Information<br />

This program book has been underwritten by Novartis<br />

Pharmaceuticals Corporation.<br />

Education<br />

<strong>Program</strong> Objectives<br />

In keeping with the purpose <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>,<br />

Inc. (<strong>ASH</strong>), the Twenty-Sixth Annual Scientific Meeting is designed to<br />

encourage and promote the development, advancement, and exchange<br />

<strong>of</strong> fair and balanced and evidence-based information regarding the<br />

research, diagnosis and treatment <strong>of</strong> hypertension and related cardiovascular<br />

diseases, with the goal <strong>of</strong> improved patient care and health.<br />

The sessions will:<br />

• Present and examine new findings on the physiology, pathophysiology,<br />

epidemiology, diagnosis, and management <strong>of</strong> hypertension<br />

and related conditions.<br />

• Review current state-<strong>of</strong>-the-art advances in managing particular<br />

groups <strong>of</strong> patients.<br />

• Evaluate specific treatment modalities and pharmacological<br />

agents.<br />

Target Audience<br />

Physicians, scientists, pharmacists, physician assistants, nurses and<br />

other health care pr<strong>of</strong>essionals with an interest in the mechanisms or<br />

management <strong>of</strong> hypertension and related diseases will benefit from<br />

attending Scientific Sessions, Satellite Symposia, Embedded Symposia,<br />

Meet the Pr<strong>of</strong>essor Sessions, Case Discussions, Poster Sessions and<br />

the Scientific Exposition.<br />

Continuing Education Credit<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. is accredited by the<br />

Accreditation Council for Continuing Medical Education to provide<br />

continuing medical education for physicians. The <strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>, Inc. designates this educational activity for a maximum<br />

<strong>of</strong> 30 AMA PRA Category 1 Credits. Each physician should claim<br />

credit commensurate with the extent <strong>of</strong> their participation in the<br />

activity.<br />

Conflict <strong>of</strong> Interest Disclosure<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. strives to ensure balance,<br />

independence, objectivity, and scientific rigor in all <strong>of</strong> its educational<br />

programs. All faculty members participating in this program have<br />

been required to disclose any real or apparent conflict(s) <strong>of</strong> interest<br />

that may have a direct bearing on the subject matter <strong>of</strong> the session in<br />

which they are participating. This includes relationships in place at<br />

the time <strong>of</strong> the meeting or in the twelve (12) months preceding the<br />

meeting, with pharmaceutical companies, biomedical device manufacturers,<br />

or other corporations whose products or services are related<br />

to the subject matter <strong>of</strong> the presentation topic.<br />

The intent <strong>of</strong> the policy is to identify openly any conflict <strong>of</strong> interest so<br />

that the listeners may form their own judgments about the presentations<br />

with the full disclosure <strong>of</strong> the facts. All Conflict <strong>of</strong> Interest Disclosure<br />

Statements are available to meeting attendees in the program<br />

book on pages 145–153 and at the <strong>ASH</strong> Information/Membership<br />

Booth located at the entrance <strong>of</strong> the <strong>Hypertension</strong> Resource Pavilion<br />

on the third Floor.<br />

9


General Information continued<br />

Disclosures not available at the time the program book was printed<br />

are included as a separate listing in the registrant bags.<br />

Dagger (†) denotes that the abstract presenting author has related<br />

disclosure information. Please reference the full Disclosure Index at<br />

the <strong>ASH</strong> Information /Membership Booth, located at the entrance<br />

<strong>of</strong> the <strong>Hypertension</strong> Resource Pavilion on the third Floor and in the<br />

Author Index <strong>of</strong> The Journal <strong>of</strong> Clinical <strong>Hypertension</strong> <strong>2011</strong> Abstract<br />

Supplement.<br />

Hilton New York Floor Layout<br />

For detailed floor plans <strong>of</strong> Exhibition and Poster Areas, see pages 154 & 155.<br />

For detailed floor plans <strong>of</strong> Hilton New York, see pages 181 – 183.<br />

10


General Information continued<br />

Meeting Venue/Headquarters Hotel<br />

Hilton NY<br />

1335 Avenue <strong>of</strong> the Americas<br />

New York, NY 10019<br />

Phone: 1-212-586-7000<br />

Fax: 1-212-315-1374<br />

Meeting Registration<br />

Registration for the Meeting will be held on the<br />

Third Floor Promenade.<br />

Registration Desk Hours<br />

Groups<br />

Friday, May 20<br />

Individuals<br />

Friday, May 20<br />

Saturday, May 21<br />

Sunday, May 22<br />

Monday, May 23<br />

Tuesday, May 24<br />

4:00 PM to 6:00 PM<br />

6:00 PM to 9:00 PM<br />

7:00 AM to 7:00 PM<br />

7:00 AM to 6:00 PM<br />

5:30 AM to 5:00 PM<br />

7:00 AM to 9:30 AM<br />

<strong>ASH</strong> Information/Membership Booth<br />

The <strong>ASH</strong> Information/Membership booth will be located at the<br />

entrance <strong>of</strong> the <strong>Hypertension</strong> Resource Pavilion on the Third Floor.<br />

Information/Membership Booth Hours<br />

Friday, May 20<br />

Saturday, May 21<br />

Sunday, May 22<br />

Monday, May 23<br />

Tuesday, May 24<br />

4:00 PM to 9:00 PM<br />

8:30 AM to 5:00 PM<br />

8:30 AM to 5:00 PM<br />

8:30 AM to 5:00 PM<br />

8:30 AM to 12:00 PM<br />

<strong>Program</strong> Information<br />

<strong>Hypertension</strong> Highlights <strong>2011</strong><br />

<strong>Hypertension</strong> Highlights is a full-day program dedicated to educating<br />

clinicians and scientists about some <strong>of</strong> the most interesting,<br />

controversial and evolving topics in the field. It is an ideal update for<br />

<strong>Hypertension</strong> Specialists and those wishing to become specialists in<br />

the field.<br />

Saturday, May 21, <strong>2011</strong><br />

8:30 AM to 3:00 PM<br />

<strong>ASH</strong> Plenary Sessions<br />

Plenary Sessions feature engaging lectures by keynote speakers. The<br />

topics are <strong>of</strong> broad general interest.<br />

Sunday, May 22, <strong>2011</strong><br />

1:15 PM to 3:00 PM<br />

Monday, May 23, <strong>2011</strong><br />

1:30 PM to 4:00 PM<br />

11


General Information continued<br />

<strong>ASH</strong> Scientific Sessions<br />

The Scientific Sessions will address basic and clinical science issues<br />

over a wide range <strong>of</strong> topics.<br />

Saturday, May 21, <strong>2011</strong><br />

4:30 PM to 6:00 PM<br />

Sunday, May 22, <strong>2011</strong><br />

3:30 PM to 5:15 PM<br />

Monday, May 23, <strong>2011</strong><br />

8:00 AM to 10:00 AM<br />

10:30 AM to 12:00 PM<br />

Tuesday, May 24, <strong>2011</strong><br />

8:15 AM to 9:30 AM<br />

10:00 AM to 11:30 AM<br />

<strong>Hypertension</strong> for the Primary Care Clinician<br />

The <strong>Hypertension</strong> for the Primary Care Clinician program will address<br />

commonplace questions that face clinicians in day-to-day care<br />

<strong>of</strong> hypertension.<br />

Sunday, May 22, <strong>2011</strong><br />

8:00 AM to 12:30 PM<br />

Joint Sessions<br />

Special Sessions jointly sponsored by <strong>Society</strong>-related organizations<br />

will enrich the knowledge base and foster new interactions between<br />

attendees.<br />

Saturday, May 21, <strong>2011</strong><br />

4:30 PM to 6:00 PM<br />

Sunday, May 22, <strong>2011</strong><br />

9:00 AM to 10:30 AM<br />

3:30 PM to 5:15 PM<br />

Monday, May 23, <strong>2011</strong><br />

8:30 AM to 10:00 AM<br />

10:30 AM to 12:00 PM<br />

Meet the Pr<strong>of</strong>essor Sessions<br />

Distinguished faculty will provide valuable instructions on (1) writing<br />

a grant; (2) developing an abstract and lecture and (3) understanding<br />

statistics in clinical research.<br />

Attendees will be admitted on a first-come, first-served basis.<br />

Sunday, May 22, <strong>2011</strong><br />

11:00 AM to 12:00 PM<br />

Clinical Debates<br />

Clinical Debates will provide for lively discussion on controversial<br />

topics.<br />

Sunday, May 22, <strong>2011</strong><br />

Monday, May 23, <strong>2011</strong><br />

11:00 AM to 12:00 PM<br />

11:45 AM to 12:15 PM<br />

4:30 PM to 5:00 PM<br />

Abstract Presentations<br />

Authors will showcase their research in oral or poster format.<br />

Saturday, May 21, <strong>2011</strong><br />

6:00 PM to 7:00 PM<br />

Sunday, May 22, <strong>2011</strong><br />

5:30 PM to 6:30 PM<br />

Monday, May 23, <strong>2011</strong><br />

4:30 PM to 5:30 PM<br />

12


General Information continued<br />

Satellite Symposia<br />

The latest information regarding new concepts, treatments, devices<br />

and techniques will be addressed in Satellite Symposia supported by<br />

educational grants.<br />

Monday, May 23, <strong>2011</strong><br />

6:00 AM to 7:30 AM<br />

<strong>ASH</strong> <strong>Hypertension</strong> Resource Pavilion - Technical Exhibits<br />

Technical Exhibits will be located in the <strong>Hypertension</strong> Resource<br />

Pavilion at the Hilton NY. <strong>ASH</strong> will host a welcome reception,<br />

lunches, and high teas in the exhibit hall.<br />

Saturday, May 21, <strong>2011</strong><br />

4:30 PM to 7:30 PM<br />

Opening Reception<br />

6:00 PM to 7:30 PM<br />

Sunday, May 22, <strong>2011</strong><br />

High Tea<br />

10:00 AM to 1:00 PM<br />

and 3:30 PM to 6:30 PM<br />

5:30 PM to 6:30 PM<br />

Monday, May 23, <strong>2011</strong><br />

High Tea<br />

10:00 AM to 1:30 PM<br />

and 4:00 PM to 5:30 PM<br />

4:30 PM to 5:30 PM<br />

Innovations Theater – Rhinelander Gallery<br />

Saturday, May 21, <strong>2011</strong><br />

6:30 PM to 7:30 PM<br />

Sunday, May 22, <strong>2011</strong><br />

12:00 PM to 1:00 PM<br />

5:30 PM to 6:30 PM<br />

<strong>2011</strong> <strong>ASH</strong> <strong>Hypertension</strong> Community Outreach<br />

<strong>ASH</strong> is proud to present its 4th Annual <strong>Hypertension</strong> Community<br />

Outreach Initiative in conjunction with the Twenty-Sixth Annual<br />

Scientific Meeting & Exposition. In 2008, <strong>ASH</strong> began the<br />

<strong>Hypertension</strong> Community Outreach Initiative in New Orleans with<br />

great success. We continued the Outreach Initiative in San Francisco<br />

in 2009 and in New York once again, in 2010.<br />

In <strong>2011</strong>, the Outreach Initiative will provide hypertension screening<br />

and education targeting local New York underinsured and uninsured<br />

population segments. <strong>ASH</strong> will educate the residents <strong>of</strong> the New York<br />

City, Long Island and New Jersey about hypertension and provide<br />

them with products and tools to take home.<br />

Visit the <strong>ASH</strong> <strong>Hypertension</strong> Community Outreach Booth #1600 in<br />

the Pavilion, learn more about the Outreach program and check your<br />

blood pressure.<br />

Multimedia CD-ROM <strong>of</strong> Scientific Meeting<br />

Audio recordings on CD-ROM including select speaker presentations<br />

in PDF format <strong>of</strong> the Scientific Sessions and Satellite Symposium will<br />

be for sale through AVMG in the Second Flood Promenade. You may<br />

also download the individual sessions in MP3 format to your computer<br />

post-conference. Visit our e-commerce store at www.ash-us.org.<br />

13


General Information continued<br />

<strong>ASH</strong> Policy Regarding Videotaping, Photography and<br />

Audio Taping<br />

No individual is permitted to film, videotape, photograph and/or<br />

audiotape meeting symposia, scientific sessions, posters or exhibits<br />

without prior written approval from the <strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>, Inc.<br />

<strong>ASH</strong> Information/Membership Booth<br />

The On-Site <strong>ASH</strong> Information/Membership Booth will be located<br />

at the entrance <strong>of</strong> the <strong>Hypertension</strong> Resource Pavilion on the Third<br />

Floor.<br />

<strong>ASH</strong> Staff Members<br />

Executive Office<br />

Torry Mark Sansone, Executive Director<br />

Mary Trifault, Executive Associate<br />

Scientific Meetings & Pr<strong>of</strong>essional Affairs<br />

Melissa Levine, Associate Executive Director<br />

Ashley Buron, <strong>Program</strong> Coordinator<br />

Meeting and Exhibit Services, <strong>Hypertension</strong> Community Outreach Services<br />

Gilda C. Caputo Hansen, Director<br />

Education Services<br />

Kathleen Sheridan, Director <strong>of</strong> Education<br />

Nicole Rabin, Associate Manager, Continuing Education (CE)<br />

Services<br />

Olivia Carr, <strong>Program</strong> Manager, Educational Services<br />

Membership & Marketing Services<br />

Angel Loayza, Manager<br />

Barbara E. Escobar, Associate Manager<br />

Financial Services<br />

Kevin Lee, Manager<br />

Kereyne A. Bishop, Associate Accounting Manager<br />

Journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> (J<strong>ASH</strong>)<br />

Ashley Buron, Managing Editor<br />

14


<strong>ASH</strong> EDUCATION AND RESEARCH<br />

FOUNDATION announces its<br />

<strong>ASH</strong> EDUCATION AND RESEARCH<br />

FOUNDATION announces its<br />

[New Logo]<br />

[New Logo]<br />

Inaugural <strong>ASH</strong> Foundation<br />

5K & 10K Run/Walk<br />

Inaugural <strong>ASH</strong> Foundation<br />

5K & 10K Run/Walk<br />

Registration:<br />

Registration:<br />

Monday, May 23 rd , <strong>2011</strong><br />

NYC Central Park<br />

7:00 AM<br />

Monday, May 23 rd , <strong>2011</strong><br />

NYC Central Park<br />

7:00 AM<br />

Daiichi Sankyo, Inc.<br />

Booth # 1200<br />

<strong>Hypertension</strong> Resource<br />

Pavilion<br />

Daiichi Sankyo, Inc.<br />

Booth # 1200<br />

<strong>Hypertension</strong> Resource<br />

Pavilion<br />

Running Shirt, Water bottle, and Course Maps<br />

will be provided upon registration.<br />

Please consider supporting the Foundation with a<br />

registration donation.<br />

Running Shirt, Water bottle, and Course Maps<br />

will be provided upon registration.<br />

Please consider supporting the Foundation with a<br />

registration donation.<br />

The Foundation thanks Daiichi Sankyo, Inc. for<br />

their generous supporting donation.


<strong>2011</strong> <strong>ASH</strong> Corporate Members<br />

Boehringer Ingelheim Pharmaceuticals, Inc.<br />

Daiichi Sankyo, Inc.<br />

Forest Laboratories, Inc.<br />

Merck & Co., Inc.<br />

Novartis Pharmaceuticals Corporation<br />

Pfizer Inc<br />

Takeda Pharmaceuticals North America, Inc.<br />

16


<strong>ASH</strong> Sponsors<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. wishes<br />

to acknowledge the following Corporate Sponsors<br />

for their generous support <strong>of</strong> the <strong>ASH</strong> Twenty-Sixth<br />

Annual Scientific Meeting.<br />

<strong>2011</strong> Annual Scientific Meeting<br />

Sponsors<br />

Daiichi Sankyo, Inc.<br />

Novartis Pharmaceuticals Corporation<br />

SERVIER<br />

Takeda Pharmaceuticals North America, Inc.<br />

<strong>2011</strong> <strong>Hypertension</strong> Community<br />

Outreach<br />

The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. wishes<br />

to acknowledge and thank our Community Partners<br />

for their generous support <strong>of</strong> this program.<br />

<strong>American</strong> Kidney Fund<br />

Association <strong>of</strong> Black Cardiologists, Spirit <strong>of</strong> the Heart<br />

AVMG, Inc.<br />

Boomer Esiason Foundation<br />

Forest Pharmacueticals, Inc.<br />

Foundation <strong>of</strong> National Lipid Association<br />

Hilton NY<br />

HoMedics, Inc.<br />

Institute for Health Equity at Nassau University Medical Center<br />

Metropolitan Exposition, Inc.<br />

MR CHAMMPS at St. Joseph’s Regional Medical Center<br />

Novartis Pharmaceuticals Corporation<br />

Omron Healthcare, Inc.<br />

PepsiCo, Inc.<br />

<strong>Society</strong> for Cardiovascular Angiography and Interventions (SCAI)<br />

17


<strong>ASH</strong> Leadership<br />

2010-<strong>2011</strong> Board <strong>of</strong> Directors<br />

Officers<br />

President: George L. Bakris, MD, F<strong>ASH</strong><br />

President-Elect: William B. White, MD, F<strong>ASH</strong><br />

Vice President: Sandra J. Taler, MD, F<strong>ASH</strong><br />

Secretary: John D. Bisognano, MD, PhD, F<strong>ASH</strong><br />

Treasurer: Franz H. Messerli, MD, F<strong>ASH</strong><br />

Immediate Past President: Henry R. Black, MD, F<strong>ASH</strong><br />

Directors-At-Large<br />

Keith C. Ferdinand, MD, F<strong>ASH</strong><br />

Alan H. Gradman, MD, F<strong>ASH</strong><br />

Daniel T. Lackland, DrPH, F<strong>ASH</strong><br />

Robert A. Phillips, MD, PhD, F<strong>ASH</strong><br />

Addison A. Taylor, MD, PhD, F<strong>ASH</strong><br />

Mattew R. Weir, MD, F<strong>ASH</strong><br />

Ex Officio Non-Voting Members<br />

Thomas D. Giles, MD, F<strong>ASH</strong>, Chair, <strong>ASH</strong> Specialists <strong>Program</strong> Inc.<br />

Michael A. Weber, MD, F<strong>ASH</strong>, Editor-In-Chief,<br />

The Journal <strong>of</strong> Clinical <strong>Hypertension</strong> (JCH)<br />

Myron H. Weinberger, MD, Editor-In-Chief,<br />

Journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> (J<strong>ASH</strong>)<br />

Torry Mark Sansone, Executive Director<br />

18


<strong>2011</strong> Scientific <strong>Program</strong><br />

Committee<br />

George L. Bakris, MD, F<strong>ASH</strong>, President<br />

William B. White, MD, F<strong>ASH</strong>, Chair<br />

Pathobiology <strong>of</strong> <strong>Hypertension</strong><br />

David G. Harrison, MD, Co-Chair<br />

Nancy J. Brown, MD<br />

Michael W. Brands, PhD<br />

Joey P. Granger, PhD<br />

Allyn L. Mark, MD<br />

Susanne B. Nicholas, MD, PhD, MPH<br />

J. Howard Pratt, MD<br />

Translational Issues in <strong>Hypertension</strong><br />

Brent M. Egan, MD, F<strong>ASH</strong>, Co-Chair<br />

Donald L. Batisky, MD<br />

John D. Bisognano, MD, PhD, F<strong>ASH</strong><br />

Stephen R. Daniels, MD, PhD, F<strong>ASH</strong><br />

Daniel Duprez, MD, PhD, F<strong>ASH</strong><br />

Keith C. Ferdinand, MD, F<strong>ASH</strong><br />

Joel Handler, MD<br />

Nancy Houston Miller, RN, BSN<br />

Therapy <strong>of</strong> <strong>Hypertension</strong><br />

Robert A. Phillips, MD, PhD, F<strong>ASH</strong>, Co-Chair<br />

Jan N. Basile, MD, F<strong>ASH</strong>*<br />

Michael J. Bloch, MD, F<strong>ASH</strong>*<br />

Lynne T. Braun, PhD, CNP<br />

Barry L. Carter, PharmD<br />

Joseph A. Diamond, MD, F<strong>ASH</strong><br />

F. Wilford Germino, MD, F<strong>ASH</strong>*<br />

David S. Kountz, MD<br />

Louis Kuritzky, MD*<br />

Gbenga Ogedegbe, MD, MPH, MS, F<strong>ASH</strong>*<br />

Aldo J. Peixoto, MD, F<strong>ASH</strong><br />

C. Venkata S. Ram, MD, F<strong>ASH</strong><br />

Scott D. Solomon, MD<br />

*Indicates Primary Care<br />

19


Special Lecture<br />

Monday, May 23, <strong>2011</strong>, 1:30 PM – 4:00 PM • East Ballroom • Third Floor<br />

Robert Tigerstedt Award Lecture<br />

Oscar A. Carretero, MD, F<strong>ASH</strong><br />

Oscar A. Carretero, MD was born in<br />

Mendoza, Argentina and received his<br />

degree from the School <strong>of</strong> Medicine at the<br />

University <strong>of</strong> Cuyo, Mendoza, Argentina.<br />

Dr. Carretero has contributed greatly to<br />

our understanding <strong>of</strong> the role <strong>of</strong> vasoactive<br />

hormones in the regulation <strong>of</strong> blood<br />

pressure and renal function, as well as the<br />

pathogenesis <strong>of</strong> hypertension and target<br />

organ damage (TOD). His research has<br />

resulted in over 360 publications. His<br />

fundamental contributions began with<br />

his initial hypothesis in 1972 that renal<br />

kinins may be involved in the regulation<br />

<strong>of</strong> sodium and water excretion, acting as natriuretic and diuretic hormones.<br />

His work has contributed uniquely to the understanding <strong>of</strong> the<br />

role <strong>of</strong> the renal kallikrein-kinin system, ranging from the development<br />

<strong>of</strong> methods to measure the components <strong>of</strong> the system and its localization<br />

to demonstrating that the renal kallikrein-kinin system is natriuretic and<br />

diuretic not only in high mineralocorticoid situations but also in the basal<br />

state. This work culminated with the demonstration that animals lacking<br />

the main kinin receptor (B2) develop hypertension when they are fed a<br />

high sodium diet. As a pioneer in the field <strong>of</strong> kinin research, where his<br />

contributions have been fundamental, numerous, and <strong>of</strong> high quality,<br />

we now understand that kinins act as paracrine hormones, regulating<br />

organ blood flow and renal function, and also participate on the chronic<br />

cardiovascular protective effect <strong>of</strong> angiotensin-converting enzyme (ACE)<br />

and angiotensin resector blockers. He and his colleagues demonstrated<br />

that kallikrein in the kidney is produced mainly in the connecting tubule<br />

(CNT) and in collaboration with Luciano Barajas they demonstrated that<br />

the CNT returns to the glomerulus and makes contact with the afferent<br />

arteriole. Recently he demonstrated that there is a crosstalk between the<br />

CNT and the afferent arteriole, showing that when sodium is increased<br />

in the perfusate <strong>of</strong> the CNT, the afferent arteriole dilates. They call this<br />

cross talk between the CNT and the afferent arteriole connecting tubuloglomerular<br />

feedback. This seminal contribution explains why during<br />

a sodium load, renal blood flow increases.<br />

Recently he has made another seminal contribution by demonstrating<br />

that the endogenous tetrapeptide N-Acetyl-Ser-Asp-Lys-Pro (Ac-SDKP);<br />

that is destroyed mainly by ACE; has anti-inflammatory and anti-fibrotic<br />

effects, and also contributes to the cardiovascular and renal protective effect<br />

<strong>of</strong> ACE inhibitors. Furthermore, he discovered that the enzyme prolyl<br />

oligopeptidase is involved in the release <strong>of</strong> Ac-SDKP from the protein<br />

thymosin β-4. He has shown that inhibition <strong>of</strong> this enzyme promotes<br />

vascular and renal fibrosis. He and his group have demonstrated that<br />

this peptide inhibits fibrosis by a) decreasing inflammation, b) fibroblast<br />

proliferation and collagen synthesis, c) TGF expression and d) its TGF<br />

signaling (Smad phosphorylation).<br />

20<br />

continued…


Special Lecture continued<br />

In addition, Dr. Carretero has trained numerous investigators in the<br />

field <strong>of</strong> hypertension. Among his distinguished and well-known students<br />

are Alberto Nasjletti, Pr<strong>of</strong>essor <strong>of</strong> Pharmacology at the Medical College<br />

<strong>of</strong> New York; A Guillermo Scicli, Pr<strong>of</strong>essor <strong>of</strong> Medicine Henry Ford<br />

Health Sciences, Wayne State University; and Sadayoshi Ito, Chairman<br />

and Pr<strong>of</strong>essor <strong>of</strong> Medicine, Tohoku University; Luis Juncos, Division<br />

Director, Nephrology, University <strong>of</strong> Mississippi. These are among many<br />

who have become important investigators in the field <strong>of</strong> cardiovascular<br />

or renal physiology and medicine.<br />

Dr. Carretero is an active invited international lecturer, and has received<br />

many awards including a Lifetime Achievement Award from the Inter-<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> and the Novartis award from the<br />

Council <strong>of</strong> High Blood Pressure Research, <strong>American</strong> Heart Association.<br />

He also received a Dr. Honoris Causa from University <strong>of</strong> Cordoba and a<br />

Pr<strong>of</strong>essor Honoris Causa from the University <strong>of</strong> Mendoza. He has been<br />

Chairman, Council for High Blood Pressure Research <strong>of</strong> the AHA, and<br />

President <strong>of</strong> the Inter-<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>. He also serves<br />

in various NIH study sections and committees and serves on the editorial<br />

boards <strong>of</strong> several scientific journals.<br />

21


Young Scholar Award*<br />

Monday, May 23, <strong>2011</strong>, 1:30 PM – 4:00 PM • East Ballroom • Third Floor<br />

Alessandro Cataliotti, MD, PhD<br />

Alessandro Cataliotti, MD, PhD, is an<br />

associate consultant in the Division <strong>of</strong><br />

Cardiovascular Diseases and Internal<br />

Medicine at Mayo Clinic Rochester. He<br />

holds the academic rank <strong>of</strong> associate<br />

pr<strong>of</strong>essor <strong>of</strong> medicine.<br />

Dr. Cataliotti obtained his medical degree<br />

with the highest score cum laude from<br />

the University <strong>of</strong> Catania, Italy where he<br />

also pursued residency and fellowship<br />

in internal medicine, as well as a PhD<br />

program in cardiovascular science. Dr.<br />

Cataliotti began a research fellowship at<br />

Mayo Clinic under the supervision <strong>of</strong> Dr. Burnett in 1998. Throughout<br />

his research career, Dr. Cataliotti has been the recipient <strong>of</strong> numerous<br />

awards, including competitive travel awards from the <strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong> in 2000 and 2003; Heart Failure <strong>Society</strong> <strong>of</strong> America in<br />

1999, 2000, 2001 and 2003; European <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> in 2001;<br />

and International <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> in 2002; and many more in<br />

the following years. Of note, Dr. Cataliotti received a two-year grant<br />

from Bristol-Myers Squibb in 1999 in support for his research here at<br />

Mayo Clinic. Dr. Cataliotti was also a recipient <strong>of</strong> a Beginning Grant in<br />

Aid from the <strong>American</strong> Heart Association in 2003-2004. From 2005 to<br />

2009, he was awarded a Ministry <strong>of</strong> Education, University and Research <strong>of</strong><br />

Italy (MIUR), Rientro dei Cervelli Project. Underscoring Dr. Cataliotti’s<br />

outstanding research achievements and again recognition by his scientific<br />

peers was the awarding <strong>of</strong> one <strong>of</strong> twelve 2006 Doris Duke Clinical Scientist<br />

Development Grants. He has been funded by the National Institutes <strong>of</strong><br />

Health and currently is the principal investigator <strong>of</strong> two RO1s.<br />

Dr. Cataliotti’s research has focused on humoral integration <strong>of</strong> the heart<br />

and kidney in heart failure and hypertension with a special emphasis<br />

upon the natriuretic peptide system. He has published over 70 publications<br />

in leading peer-reviewed journals, including the Circulation,<br />

Lancet, Proceedings <strong>of</strong> The National Academy <strong>of</strong> Science, <strong>American</strong><br />

Journal <strong>of</strong> Physiology, Kidney International, Journal <strong>of</strong> <strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> Nephrology, <strong>American</strong> Journal <strong>of</strong> Kidney Disease, Peptide, Journal <strong>of</strong><br />

<strong>Hypertension</strong>, Regulatory Peptides, European Journal <strong>of</strong> Heart Failure,<br />

<strong>Hypertension</strong>, Circulation Research, <strong>American</strong> Journal <strong>of</strong> <strong>Hypertension</strong><br />

and the Mayo Clinic Proceedings.<br />

Dr. Cataliotti has been active in the discovery <strong>of</strong> novel drug delivery<br />

strategies for cardiac peptides in cardiovascular disease and in hypertension.<br />

He was the first to report feasibility <strong>of</strong> oral delivery <strong>of</strong> human<br />

B-type natriuretic peptide in experimental hypertension, and has<br />

pioneered the cardiac gene delivery strategy for natriuretic peptides in<br />

hypertensive heart disease.<br />

*Supported by an educational grant from SERVIER.<br />

22


Young Scholar Award*<br />

Monday, May 23, <strong>2011</strong>, 1:30 PM – 4:00 PM • East Ballroom • Third Floor<br />

Michael J. Ryan, PhD<br />

Dr. Ryan is an Associate Pr<strong>of</strong>essor <strong>of</strong><br />

Physiology & Biophysics at the University<br />

<strong>of</strong> Mississippi Medical Center in Jackson,<br />

MS. He earned his doctorate from the<br />

State University <strong>of</strong> New York at Buffalo<br />

in 1999 and received his post-doctoral<br />

training at the University <strong>of</strong> Iowa from<br />

1999-2004. In 2004, he was recruited as<br />

an Assistant Pr<strong>of</strong>essor <strong>of</strong> Physiology &<br />

Biophysics at the University <strong>of</strong> Mississippi<br />

Medical Center where he rose to his current<br />

rank <strong>of</strong> Associate Pr<strong>of</strong>essor in 2009.<br />

Dr. Ryan’s research focuses on the<br />

mechanistic role that chronic inflammation has in the development <strong>of</strong><br />

hypertension. In order to examine this link, he studies an animal model<br />

that develops the chronic autoimmune inflammatory disorder systemic<br />

lupus erythematosus (SLE). <strong>Hypertension</strong> is prevalent and cardiovascular<br />

disease is a leading cause <strong>of</strong> death in individuals with SLE. Dr. Ryan is<br />

specifically interested in the effect <strong>of</strong> immune and inflammatory mediators<br />

on renal function, renal injury and vascular physiology as it pertains to<br />

the development <strong>of</strong> hypertension. His work has been continuously funded<br />

by the <strong>American</strong> Heart Association and National Institutes <strong>of</strong> Health.<br />

Dr. Ryan currently sits on the editorial board <strong>of</strong> <strong>Hypertension</strong>, the <strong>American</strong><br />

Journal <strong>of</strong> Physiology: Regulatory, Integrative and Comparative Physiology,<br />

the Journal <strong>of</strong> <strong>Hypertension</strong> and Frontiers in Vascular Physiology.<br />

He is an active member <strong>of</strong> the <strong>American</strong> Heart Association peer review<br />

system serving as a co-chair <strong>of</strong> the Vascular Biology & Blood Pressure<br />

II peer review committee. Dr. Ryan is a Fellow <strong>of</strong> the <strong>American</strong> Heart<br />

Association and serves on the Leadership Committee <strong>of</strong> the Council<br />

for High Blood Pressure as well as on the Greater Southeast Affiliate<br />

Research Committee. Ryan is also an active member <strong>of</strong> the <strong>American</strong><br />

Physiological <strong>Society</strong>. He has served on the Porter Physiology Development<br />

Committee and currently serves on the Education Committee <strong>of</strong><br />

the <strong>American</strong> Physiological <strong>Society</strong> where he actively contributes to the<br />

educational missions <strong>of</strong> the society.<br />

*Supported by an educational grant from SERVIER.<br />

23


Special Lecture<br />

Monday, May 23, <strong>2011</strong>, 1:30 PM – 4:00 PM • East Ballroom • Third Floor<br />

Marvin Moser Clinical <strong>Hypertension</strong> Award Lecture<br />

Murray Epstein, MD<br />

Dr. Murray Epstein is Pr<strong>of</strong>essor <strong>of</strong> Medicine<br />

at the University <strong>of</strong> Miami, School<br />

<strong>of</strong> Medicine. He was a recipient <strong>of</strong> the<br />

1990 Distinguished Scientist Award <strong>of</strong> the<br />

National Kidney Foundation. He served<br />

as a member <strong>of</strong> the National High Blood<br />

Pressure Education <strong>Program</strong> Coordinating<br />

Committee and is a contributor to the 6th<br />

Report <strong>of</strong> the Joint National Committee.<br />

Dr. Epstein is listed in Who’s Who in<br />

America (59th, 60th and 61st edition) and<br />

Who’s Who in Medicine.<br />

Dr. Epstein has authored over 400 journal<br />

articles and book chapters. Many <strong>of</strong> these have related to 1) the pathogenesis<br />

and management <strong>of</strong> hypertension, 2) renal function in diseases<br />

characterized by abnormal volume regulation, and 3) the role <strong>of</strong> the<br />

renin angiotensin aldosterone system. He has also written extensively<br />

on head out water immersion, a unique clinical investigational model<br />

that he has defined and applied to the study <strong>of</strong> a wide range <strong>of</strong> disease<br />

states. The unique attributes <strong>of</strong> this clinical investigative model include<br />

a prompt redistribution <strong>of</strong> circulating blood volume with a consequent<br />

relative central hypervolemia, in the absence <strong>of</strong> concomitant changes in<br />

plasma composition. Dr. Epstein has successfully applied the immersion<br />

model as a clinical investigative tool to characterize the determinants<br />

<strong>of</strong> deranged volume homeostasis and renin-aldosterone, eicosanoid,<br />

kallikrein, vasopressin and ANF responsiveness in diverse edematous<br />

disorders including advanced liver diseases, chronic renal failure and<br />

hypertension. He has also utilized the immersion model to define the<br />

relative roles <strong>of</strong> volume and the renin-angiotensin axis as determinants<br />

<strong>of</strong> aldosterone responsiveness in anephric humans.<br />

Dr. Epstein has also defined the effects <strong>of</strong> calcium antagonists on renal<br />

hemodynamics and renal function At the preclinical level Dr. Epstein,<br />

in collaboration with his co-investigator Dr. Rodger Loutzenhiser, developed<br />

and used the isolated perfused hydronephrotic kidney model to<br />

visualize the renal microvasculature and define the effect <strong>of</strong> interventions<br />

with calcium antagonists and a wide array <strong>of</strong> vasoconstrictors including<br />

angiotensin II and endothelin on the afferent and efferent arterioles. He<br />

extended these studies to the clinical arena in order to define the effect <strong>of</strong><br />

calcium antagonists on renal hemodynamics and as prophylactic agents<br />

to obviate acute renal failure in diverse clinical settings. Most recently<br />

Dr. Epstein has focused his clinical and investigative attention on the<br />

role <strong>of</strong> aldosterone as a pivotal determinant <strong>of</strong> cardiovascular and renal<br />

injury, and the use <strong>of</strong> aldosterone blockade to reverse these adverse<br />

effects. Currently his major investigative focus is on mineralocorticoid<br />

receptor blockade as an intervention to abrogate progressive kidney disease,<br />

and as an intervention to confer cardiovascular and renal benefits<br />

in patients with chronic kidney disease, and in ESRD patients who are<br />

being treated by hemodialysis.<br />

24<br />

continued…


Special Lecture continued<br />

A member <strong>of</strong> several editorial boards, Dr. Epstein also serves as a<br />

reviewer for numerous prominent journals and for study sections for<br />

granting agencies.<br />

Dr. Epstein has served as the editor <strong>of</strong> 4 editions <strong>of</strong> THE KIDNEY IN<br />

LIVER DISEASE (Hanley & Belfus, Philadelphia, 1996), the premier<br />

book in the field, which surveys the wide spectrum <strong>of</strong> renal functional<br />

abnormalities in liver disease. Dr. Epstein has also co authored HYPER-<br />

TENSION: PRACTICAL MANAGEMENT (1988), which has subsequently<br />

been published in Spanish and Portuguese editions. He has also edited<br />

CALCIUM ANTAGONISTS AND THE KIDNEY (Hanley & Belfus, 1990),<br />

the first comprehensive book to survey the diverse effects <strong>of</strong> calcium<br />

antagonists on renal function, and the clinical applicability <strong>of</strong> these findings,<br />

including renal protection. Most recently, Dr. Epstein has edited<br />

3 editions <strong>of</strong> CALCIUM ANTAGONISTS IN CLINICAL MEDICINE<br />

(Hanley and Belfus, 1992, 1997, and 2002), the first comprehensive book<br />

to survey the effects <strong>of</strong> calcium antagonists on both cardiovascular and<br />

renal function. In addition, this book considers the effects <strong>of</strong> calcium<br />

antagonists on other organ systems including the management <strong>of</strong> gastrointestinal<br />

disorders, and disorders <strong>of</strong> the cerebral circulation.<br />

Dr. Epstein has also co-edited ANGIOTENSIN II RECEPTOR ANTAGO-<br />

NISTS (Hanley & Belfus 2001), the first comprehensive book to survey<br />

the effects <strong>of</strong> AT1 receptor antagonists on both cardiovascular and renal<br />

function. In addition, this book considers the effects <strong>of</strong> these novel agents<br />

in elucidating the pr<strong>of</strong>ound physiological effects <strong>of</strong> angiotensin II.<br />

Dr. Epstein, who is a 1963 graduate <strong>of</strong> Columbia University College <strong>of</strong><br />

Physicians and Surgeons, did his postgraduate medical training at University<br />

Hospital in Madison, Wisconsin and at the Cleveland MetroHealth<br />

Medical Center <strong>of</strong> Western Reserve University from 1966 to 1968, he<br />

was a Research Fellow in Nephrology in the Kidney Laboratory <strong>of</strong> Peter<br />

Bent Brigham Hospital in Boston, under Pr<strong>of</strong>essor John P. Merrill. Dr.<br />

Epstein was also an Established Investigator <strong>of</strong> the Howard Hughes<br />

Medical Institute. He is ABIM-certified in internal medicine and nephrology,<br />

and is a Fellow <strong>of</strong> both the <strong>American</strong> College <strong>of</strong> Physicians and the<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> Nephrology. Dr Epstein has also been designated<br />

a <strong>Hypertension</strong> Specialist by the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>.<br />

25


<strong>2011</strong> Abstract Reviewers<br />

Lawrence J. Appel, MD, MPH,<br />

F<strong>ASH</strong><br />

Baltimore, MD<br />

Steven A. Atlas, MD, F<strong>ASH</strong><br />

Bronx, NY<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

Chicago, IL<br />

Jan N. Basile, MD, F<strong>ASH</strong><br />

Charleston, SC<br />

Donald L. Batisky, MD<br />

Atlanta, GA<br />

Dan R. Berlowitz, MD, MPH<br />

Bedford, MA<br />

John D. Bisognano, MD, PhD,<br />

F<strong>ASH</strong><br />

Rochester, NY<br />

Henry R. Black, MD, F<strong>ASH</strong><br />

New York, NY<br />

Michael J. Bloch, MD, F<strong>ASH</strong><br />

Reno, NV<br />

Michael W. Brands, PhD<br />

Augusta, GA<br />

Lynne T. Braun, PhD, CNP<br />

Chicago, IL<br />

Robert D. Brook, MD, F<strong>ASH</strong><br />

Ann Arbor, MI<br />

Angela L. Brown, MD<br />

St. Louis, MO<br />

David A. Calhoun, MD<br />

Birmingham, AL<br />

Oscar A. Carretero, MD, F<strong>ASH</strong><br />

Detroit, MI<br />

Barry L. Carter, PharmD<br />

Iowa City, IA<br />

John R. Cockcr<strong>of</strong>t, MD<br />

Cardiff, United Kingdom<br />

Stephen R. Daniels, MD, PhD,<br />

F<strong>ASH</strong><br />

Aurora, CO<br />

Prakash C. Deedwania, MD,<br />

F<strong>ASH</strong><br />

Fresno, CA<br />

Joseph A. Diamond, MD, F<strong>ASH</strong><br />

New Hyde Park, NY<br />

Daniel Duprez, MD, PhD,<br />

F<strong>ASH</strong><br />

Minneapolis, MN<br />

Brent M. Egan, MD, F<strong>ASH</strong><br />

Charleston, SC<br />

Gilbert M. Eisner, MD, F<strong>ASH</strong><br />

Washington, DC<br />

William J. Elliott, MD, PhD,<br />

F<strong>ASH</strong><br />

Yakima, WA<br />

Michael Ernst, PharmD<br />

Iowa City, IA<br />

Bonita Falkner, MD, F<strong>ASH</strong><br />

Philadelphia, PA<br />

Pamela J. Fall, MD, F<strong>ASH</strong><br />

Augusta, GA<br />

Daniel I. Feig, MD, PhD<br />

Houston, TX<br />

John M. Flack, MD, MPH<br />

Detroit, MI<br />

Joseph T. Flynn, MD, F<strong>ASH</strong><br />

Seattle, WA<br />

Philip B. Gorelick, MD, MPH<br />

Lincoln, IL<br />

Alan H. Gradman, MD, F<strong>ASH</strong><br />

Pittsburgh, PA<br />

Joey P. Granger, PhD<br />

Jackson, MS<br />

Richard H. Grimm, Jr., MD, PhD<br />

Minneapolis, MN<br />

John E. Hall, PhD<br />

Jackson, MS<br />

Joel Handler, MD<br />

Anaheim, CA<br />

Willa A. Hsueh, MD<br />

Houston, TX<br />

David J. Hyman, MD, MPH<br />

Houston, TX<br />

Kenneth A. Jamerson, MD, F<strong>ASH</strong><br />

Ann Arbor, MI<br />

Richard J. Johnson, MD<br />

Denver, CO<br />

John B. Kostis, MD, F<strong>ASH</strong><br />

New Brunswick, NJ<br />

David S. Kountz, MD<br />

Neptune, NJ<br />

Louis Kuritzky, MD<br />

Gainesville, FL<br />

Theodore W. Kurtz, MD<br />

San Francisco, CA<br />

Daniel T. Lackland, DrPH, F<strong>ASH</strong><br />

Charleston, SC<br />

Lewis Landsberg, MD<br />

Chicago, IL<br />

26


<strong>2011</strong> Abstract Reviewers continued<br />

Friedrich C. Luft, MD<br />

Berlin, Germany<br />

Giuseppe Mancia, MD<br />

Milan, Italy<br />

Samuel J. Mann, MD<br />

New York, NY<br />

Allyn L. Mark, MD<br />

Iowa City, IA<br />

Nancy Houston Miller, RN,<br />

BSN<br />

Palo Alto, CA<br />

Gary Mitchell, MD<br />

Norwood, MA<br />

Michael A. Moore, MD, F<strong>ASH</strong><br />

Winston Salem, NC<br />

L. Gabriel Navar, PhD<br />

New Orleans, LA<br />

Shawna D. Nesbitt, MD, MS,<br />

F<strong>ASH</strong><br />

Dallas, TX<br />

Susanne B. Nicholas, MD, PhD,<br />

MPH<br />

Los Angeles, CA<br />

Daniel T. O’Connor, MD<br />

San Diego, CA<br />

Gbenga Ogedegbe, MD, MPH,<br />

MS, F<strong>ASH</strong><br />

New York, NY<br />

Suzanne Oparil, MD, F<strong>ASH</strong><br />

Birmingham, AL<br />

Vasilios Papademetriou, MD,<br />

F<strong>ASH</strong><br />

Washington, DC<br />

Aldo J. Peixoto, MD, F<strong>ASH</strong><br />

West Haven, CT<br />

Robert A. Phillips, MD, PhD,<br />

F<strong>ASH</strong><br />

Worcester, MA<br />

Bertram Pitt, MD<br />

Ann Arbor, MI<br />

J. Howard Pratt, MD<br />

Indianapolis, IN<br />

L. Michael Prisant, MD, F<strong>ASH</strong><br />

Augusta, GA<br />

Clive Rosendorff, MD, PhD,<br />

F<strong>ASH</strong><br />

Bronx, NY<br />

Gary E. Sander, MD, PhD,<br />

F<strong>ASH</strong><br />

Metairie, LA<br />

Ernesto L. Schiffrin, MD, PhD<br />

Montreal, Canada<br />

Alan B. Schwartz, MD, F<strong>ASH</strong><br />

Philadelphia, PA<br />

Scott D. Solomon, MD<br />

Boston, MA<br />

James R. Sowers, MD, F<strong>ASH</strong><br />

Columbia, MO<br />

Jan A. Staessen, MD, PhD<br />

Leuven, Belgium<br />

Sandra J. Taler, MD, F<strong>ASH</strong><br />

Rochester, MN<br />

Addison A. Taylor, MD, PhD,<br />

F<strong>ASH</strong><br />

Houston, TX<br />

Sheldon W. Tobe, MD, F<strong>ASH</strong><br />

Toronto, Canada<br />

Peter P. Toth, MD, PhD<br />

Sterling, IL<br />

Rhian M. Touyz, MD, PhD<br />

Ottawa, Canada<br />

Raymond R. Townsend, MD<br />

Philadelphia, PA<br />

Jason G. Umans, MD, PhD<br />

Bethesda, MD<br />

Alan B. Weder, MD<br />

Ann Arbor, MI<br />

Myron H. Weinberger, MD<br />

Indianapolis, IN<br />

Howard Weintraub, MD<br />

New York, NY<br />

Matthew R. Weir, MD, F<strong>ASH</strong><br />

Baltimore, MD<br />

William B. White, MD, F<strong>ASH</strong><br />

Farmington, CT<br />

Peter W. F. Wilson, MD<br />

Atlanta, GA<br />

Nathan D. Wong, PhD, MPH<br />

Irvine, CA<br />

Jackson T. Wright, Jr., MD,<br />

PhD, F<strong>ASH</strong><br />

Cleveland, OH<br />

Steven A. Yarows, MD, F<strong>ASH</strong><br />

Chelsea, MI<br />

27


More than half <strong>of</strong><br />

hypertensive patients need<br />

3 or more<br />

agents<br />

to help them get to BP GOAL 1-4<br />

References: 1. Pepine CJ, Handberg EM, Cooper-DeH<strong>of</strong>f RM, et al; INVEST Investigators. A calcium antagonist vs<br />

a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International<br />

Verapamil-Trandolapril Study (INVEST): a randomized controlled trial. JAMA. 2003;290(21):2805-2816. 2. Wright<br />

JT Jr, Bakris G, Greene T, et al; African <strong>American</strong> Study <strong>of</strong> Kidney Disease and <strong>Hypertension</strong> Study Group. Effect <strong>of</strong><br />

blood pressure lowering and antihypertensive drug class on progression <strong>of</strong> hypertensive kidney disease: results from<br />

the AASK trial. JAMA. 2002;288(19):2421-2431. 3. Cushman WC, Ford CE, Cutler JA, et al; ALLHAT Collaborative<br />

Research Group. Success and predictors <strong>of</strong> blood pressure control in diverse North <strong>American</strong> settings: the<br />

Antihypertensive and Lipid-lowering Treatment to Prevent Heart Attack trial (ALLHAT). J Clin Hypertens. 2002;4(6):393-<br />

404. 4. Jamerson K, Weber MA, Bakris GL, et al; ACCOMPLISH Trial Investigators. Benazepril plus amlodipine or<br />

hydrochlorothiazide for hypertension in high-risk patients. N Engl J Med. 2008;359(23):2417-2428. 5. Flack JM,<br />

Calhoun DA, Satlin L, Barbier M, Hilkat R, Brunel P. Efficacy and safety <strong>of</strong> initial combination therapy with amlodipine/<br />

valsartan compared with amlodipine monotherapy in black patients with stage 2 hypertension: the EX-STAND study.<br />

J Hum Hypertens. 2009;23(7):479-489. 6. Flack JM, Sica DA, Bakris G, et al. Management <strong>of</strong> high blood pressure<br />

in blacks: an update <strong>of</strong> the International <strong>Society</strong> on <strong>Hypertension</strong> in Blacks consensus statement. <strong>Hypertension</strong>.<br />

2010;56(5):780-800.<br />

Novartis Pharmaceuticals Corporation<br />

East Hanover, New Jersey 07936<br />

©<strong>2011</strong> Novartis


Looking for<br />

antihypertensive<br />

EFFICACY<br />

in African <strong>American</strong><br />

patients 5,6, *<br />

Visit booth<br />

#1100<br />

to find out more<br />

* Patients with stage 2/severe hypertension, including African <strong>American</strong> patients with moderate-to-severe<br />

hypertension. Stage 2 hypertension is defined as ≥160/100 mm Hg.<br />

Printed in USA 4/11 EXR-1052006


Poster Category Presentation<br />

Posters will be displayed in the Second Floor Promenade.<br />

Saturday, May 21, <strong>2011</strong><br />

Posters on Display: 4:30 PM – 7:30 PM • Poster Viewing: 6:00 PM – 7:00 PM<br />

Adolescent <strong>Hypertension</strong> and Obesity.............................. (PO-1 – PO-5)<br />

Antiatherosclerotic Drugs................................................... (PO-6 – PO-7)<br />

Cardiac Structure and Function/Imaging....................... (PO-8 – PO-10)<br />

Comprehensive Multi-Level Interventions for<br />

<strong>Hypertension</strong> Management in High-Risk Groups......(PO-11 – PO-30)<br />

Endothelial Function.......................................................(PO-31 – PO-45)<br />

Epidemiology/Special Populations................................(PO-46 – PO-78)<br />

Immune Mechanisms in <strong>Hypertension</strong>........................(PO-79 – PO-82)<br />

Metabolic Syndrome (Diabetes/Glycemic Control;<br />

Dysglycemic Drugs; Insulin Resistance).....................(PO-83 – PO-102)<br />

New Insights into the Role <strong>of</strong> Uric Acid<br />

in <strong>Hypertension</strong>............................................................(PO-103 – PO-104)<br />

Pediatric <strong>Hypertension</strong>...............................................(PO-105 – PO-111)<br />

Risk Factors (Lipids)....................................................(PO-112 – PO-115)<br />

Stroke.............................................................................(PO-117 – PO-119)<br />

Vascular Injury/Inflammation and Remodeling......(PO-120 – PO-123)<br />

Sunday, May 22, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 6:30 PM • Poster Viewing: 5:30 PM – 6:30 PM<br />

Featured Posters<br />

Blood Pressure Measurement/Monitoring......................(FP-1 – FP-4)<br />

Adolescent <strong>Hypertension</strong>..................................................(FP-5 – FP-8)<br />

Aldosterone and Anti-Aldosterone Agents..............(PO-124 – PO-130)<br />

Antihypertensive Drugs and Pharmacology............(PO-131 – PO-157)<br />

Clinical Trials................................................................(PO-158 – PO-184)<br />

Coronary Artery Disease............................................(PO-185 – PO-191)<br />

Genetics/Gene Therapy/Proteomics..........................(PO-192 – PO-198)<br />

Heart Failure/Hypertrophy<br />

(Diastolic Dysfunction)...............................................(PO-199 – PO-216)<br />

<strong>Hypertension</strong> in Patients with Chronic<br />

Kidney Disease.............................................................(PO-217 – PO-226)<br />

Kidney and <strong>Hypertension</strong>...........................................(PO-227 – PO-242)<br />

Off-Target Cardiovascular Effects <strong>of</strong><br />

Non-Cardiovascular Drugs........................................(PO-243 – PO-244)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

30


Poster Category Presentation<br />

Monday, May 23, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 5:30 PM • Poster Viewing: 4:30 PM – 5:30 PM<br />

Featured Posters<br />

Cardiac Structure and Function.................................... (FP-9 – FP-13)<br />

Arterial Structure and Compliance...........................(PO-245 – PO-259)<br />

Blood Pressure Measurement/Monitoring............(PO-260 – PO-305A)<br />

Cellular Mechanisms (Cell Biology;<br />

Cell Membrane Transport/Ion Channels;<br />

Coagulation/Thrombosis; Growth Factors).............(PO-306 – PO-308)<br />

Lipid Metabolism...........................................................................(PO-309)<br />

Neural Hormonal Mechanisms (Renin; Neural Control; Vasoactive<br />

Autacoids).....................................................................(PO-310 – PO-312)<br />

Non – Pharmacological Therapy (Alternative<br />

Medicine; Diet; Physical Activity).............................(PO-313 – PO-322)<br />

Nutrition and Cardiovascular Prevention................(PO-323 – PO-330)<br />

Obesity...........................................................................(PO-331 – PO-339)<br />

Patient – Provider-Healthcare System Issues...........(PO-340 – PO-355)<br />

Preclinical Models/Experimental <strong>Hypertension</strong>.....(PO-357 – PO-358)<br />

Pregnancy......................................................................(PO-359 – PO-361)<br />

Salt-Sensitive Mechanisms <strong>of</strong> <strong>Hypertension</strong>............(PO-362 – PO-364)<br />

Secondary <strong>Hypertension</strong>.............................................(PO-365 – PO-367)<br />

Late-Breaking Posters.........................................(LB-PO-01 – LB-PO-03)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

31


<strong>2011</strong> <strong>ASH</strong> Faculty<br />

Rajiv Agarwal, MD<br />

Indianapolis, IN<br />

Lawrence J. Appel, MD, MPH,<br />

F<strong>ASH</strong><br />

Baltimore, MD<br />

Nancy Artinian, PhD, RN<br />

Detroit, MI<br />

Phyllis August, MD, MPH<br />

New York, NY<br />

Abraham Aviv, MD<br />

Newark, NJ<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

Chicago, IL<br />

Jan N. Basile, MD, F<strong>ASH</strong><br />

Charleston, SC<br />

Donald L. Batisky, MD<br />

Atlanta, GA<br />

John D. Bisognano, MD, PhD,<br />

F<strong>ASH</strong><br />

Rochester, NY<br />

Henry R. Black, MD, F<strong>ASH</strong><br />

New York, NY<br />

Michael J. Bloch, MD, F<strong>ASH</strong><br />

Reno, NV<br />

William E. Boden, MD<br />

Buffalo, NY<br />

Michael W. Brands, PhD<br />

Augusta, GA<br />

Lynne T. Braun, PhD, CNP<br />

Chicago, IL<br />

Emmanuel Bravo, MD<br />

Cleveland, OH<br />

Angela L. Brown, MD<br />

St. Louis, MO<br />

Nancy J. Brown, MD<br />

Nashville, TN<br />

David A. Bushinsky, MD<br />

Rochester, NY<br />

Norman R. C. Campbell, MD<br />

Calgary, Canada<br />

Oscar A. Carretero, MD<br />

Detroit, MI<br />

Barry L. Carter, PharmD<br />

Iowa City, IA<br />

Alessandro Cataliotti, MD, PhD<br />

Rochester, MN<br />

John R. Cockcr<strong>of</strong>t, MD<br />

Cardiff, United Kingdom<br />

Jay N. Cohn, MD<br />

Minneapolis, MN<br />

Steven D. Crowley, PhD<br />

Durham, NC<br />

William C. Cushman, MD,<br />

F<strong>ASH</strong><br />

Memphis, TN<br />

Stephen R. Daniels, MD, PhD,<br />

F<strong>ASH</strong><br />

Aurora, CO<br />

Michael H. Davidson, MD<br />

Chicago, IL<br />

Daniel Duprez, MD, PhD,<br />

F<strong>ASH</strong><br />

Minneapolis, MN<br />

Lance D. Dworkin, MD<br />

Providence, RI<br />

Brent M. Egan, MD, F<strong>ASH</strong><br />

Charleston, SC<br />

Paula T. Einhorn, MD, MS<br />

Bethesda, MD<br />

William J. Elliott, MD, PhD,<br />

F<strong>ASH</strong><br />

Yakima, WA<br />

Murray Epstein, MD<br />

Miami, FL<br />

Murray D. Esler, MBBS, PhD<br />

Melbourne, Australia<br />

Bonita Falkner, MD, F<strong>ASH</strong><br />

Philadelphia, PA<br />

Sadaf Farooqi, PhD<br />

Cambridge, United Kingdom<br />

Daniel I. Feig, MD, PhD<br />

Houston, TX<br />

Ross Feldman, MD<br />

London, Canada<br />

Keith C. Ferdinand, MD, F<strong>ASH</strong><br />

Atlanta, GA<br />

John M. Flack, MD, MPH<br />

Detroit, MI<br />

Joseph T. Flynn, MD, F<strong>ASH</strong><br />

Seattle, WA<br />

Stanley S. Franklin, MD, F<strong>ASH</strong><br />

Los Angeles, CA<br />

William H. Frishman, MD<br />

Valhalla, NY<br />

James B. Froehlich, MD, MPH<br />

Ann Arbor, MI<br />

Leonard M. Fromer, MD<br />

Los Angeles, CA<br />

Jeffrey L. Garvin, PhD<br />

Detroit, MI<br />

32


<strong>2011</strong> <strong>ASH</strong> Faculty continued<br />

Haralambos Gavras, MD<br />

Boston, MA<br />

F. Wilford Germino, MD, F<strong>ASH</strong><br />

Orland Park, IL<br />

Ali G. Gharavi, MD<br />

New York, NY<br />

Thomas D. Giles, MD, F<strong>ASH</strong><br />

New Orleans, LA<br />

Alan S. Go, MD<br />

Oakland, CA<br />

Alan H. Gradman, MD, F<strong>ASH</strong><br />

Pittsburgh, PA<br />

Joey P. Granger, PhD<br />

Jackson, MS<br />

Richard H. Grimm, Jr., MD,<br />

PhD<br />

Minneapolis, MN<br />

Yuan Guo, MD, MS<br />

Beijing, China<br />

John E. Hall, PhD<br />

Jackson, MS<br />

Joel Handler, MD<br />

Anaheim, CA<br />

David Harder, MD, PhD<br />

Milwaukee, WI<br />

Raymond C. Harris, MD<br />

Nashville, TN<br />

David G. Harrison, MD<br />

Atlanta, GA<br />

Joseph A. Hill, MD, PhD<br />

Dallas, TX<br />

Norman K. Hollenberg, MD,<br />

PhD<br />

Boston, MA<br />

Suzanne Hughes, RN, MSN<br />

Akron, OH<br />

Joseph L. Izzo, Jr., MD, F<strong>ASH</strong><br />

Buffalo, NY<br />

Edgar A. Jaimes, MD<br />

Birmingham, AL<br />

Kenneth A. Jamerson, MD,<br />

F<strong>ASH</strong><br />

Ann Arbor, MI<br />

Julie A. Johnson, PharmD<br />

Gainesville, FL<br />

Richard J. Johnson, MD<br />

Denver, CO<br />

Pedro A. Jose, MD<br />

Washington, DC<br />

Luis Juncos, MD<br />

Córdoba, Argentina<br />

Rae-Ellen W. Kavey, MD, MPH<br />

Rochester, NY<br />

Donald E. Kohan, MD, PhD<br />

Salt Lake City, UT<br />

David S. Kountz, MD<br />

Neptune, NJ<br />

Lawrence R. Krak<strong>of</strong>f, MD<br />

New York, NY<br />

Henry Krum, MBBS, PhD<br />

Melbourne, Australia<br />

Louis Kuritzky, MD<br />

Gainesville, FL<br />

Theodore W. Kurtz, MD<br />

San Francisco, CA<br />

Robert F. Kushner, MD<br />

Chicago, IL<br />

Daniel T. Lackland, DrPH,<br />

F<strong>ASH</strong><br />

Charleston, SC<br />

Edward G. Lakatta, MD<br />

Baltimore, MD<br />

Babbette LaMarca, PhD<br />

Jackson, MS<br />

Marc B. Lande, MD, MPH<br />

Rochester, NY<br />

Daniel Levy, MD<br />

Framingham, MA<br />

Nita A. Limdi, PharmD, PhD,<br />

MSPH<br />

Birmingham, AL<br />

Tianhu Liu, MD<br />

Chengdu, China<br />

Charles J. Lowenstein, MD<br />

Rochester, NY<br />

Jianfang Luo, MD<br />

Guangzhou, China<br />

James M. Luther, MD<br />

Nashville, TN<br />

Guiseppe Mancia, MD<br />

Milan, Italy<br />

Samuel J. Mann, MD<br />

New York, NY<br />

Athanasios J. Manolis, MD,<br />

PhD<br />

Athens, Greece<br />

Allyn L. Mark, MD<br />

Iowa City, IA<br />

Barry J. Materson, MD, MBA,<br />

F<strong>ASH</strong><br />

Miami, FL<br />

33


<strong>2011</strong> <strong>ASH</strong> Faculty continued<br />

David L. Mattson, PhD<br />

Milwaukee, WI<br />

Richard J. McManus, MD<br />

Birmingham, United Kingdom<br />

John Merenich, MD<br />

Denver, CO<br />

Franz H. Messerli, MD, F<strong>ASH</strong><br />

New York, NY<br />

Nancy Houston Miller, RN,<br />

BSN<br />

Palo Alto, CA<br />

Mark E. Molitch, MD<br />

Chicago, IL<br />

Krzyszt<strong>of</strong> Narkiewicz, MD,<br />

PhD<br />

Gdánsk, Poland<br />

L. Gabriel Navar, PhD<br />

New Orleans, LA<br />

Shawna D. Nesbitt, MD, MS,<br />

F<strong>ASH</strong><br />

Dallas, TX<br />

Joel M. Neutel, MD, F<strong>ASH</strong><br />

Tustin, CA<br />

Susanne B. Nicholas, MD, PhD,<br />

MPH<br />

Los Angeles, CA<br />

Eoin O’Brien, MD<br />

Dublin, Ireland<br />

Gbenga Ogedegbe, MD, MPH,<br />

MS, F<strong>ASH</strong><br />

New York, NY<br />

Suzanne Oparil, MD, F<strong>ASH</strong><br />

Birmingham, AL<br />

Julio A. Panza, MD<br />

Washington, DC<br />

Vasilios Papademetriou, MD,<br />

F<strong>ASH</strong><br />

Washington, DC<br />

Gianfranco Parati, MD<br />

Milan, Italy<br />

Aldo J. Peixoto, MD, F<strong>ASH</strong><br />

West Haven, CT<br />

Robert A. Phillips, MD, PhD,<br />

F<strong>ASH</strong><br />

Worcester, MA<br />

Thomas A. Pearson, MD, PhD,<br />

MPH<br />

Rochester, NY<br />

F. Xavier Pi-Sunyer, MD, MPH<br />

New York, NY<br />

Bertram Pitt, MD<br />

Ann Arbor, MI<br />

Velvie A. Pogue, MD<br />

New York, NY<br />

David M. Pollock, PhD<br />

Augusta, GA<br />

J. Howard Pratt, MD<br />

Indianapolis, IN<br />

Henry A. Punzi, MD<br />

Carrollton, TX<br />

Leopoldo Raij, MD, F<strong>ASH</strong><br />

Miami, FL<br />

C. Venkata S. Ram, MD, F<strong>ASH</strong><br />

Dallas, TX<br />

James Rippe, MD<br />

Shrewsbury, MA<br />

Talma Rosenthal, MD<br />

Tel Aviv, Israel<br />

Peter M. Rothwell, MD<br />

Oxford, United Kingdom<br />

Luis M. Ruilope, MD<br />

Madrid, Spain<br />

Michael J. Ryan, PhD<br />

Jackson, MS<br />

Elijah Saunders, MD, F<strong>ASH</strong><br />

Baltimore, MD<br />

Ernesto L. Schiffrin, MD, PhD<br />

Montreal, Canada<br />

Roland E. Schmieder, MD<br />

Erlangen, Germany<br />

Antoinette Schoenthaler, EdD<br />

New York, NY<br />

Domenic A. Sica, MD<br />

Richmond, VA<br />

Sidney Smith, Jr., MD<br />

Chapel Hill, NC<br />

Matthew Sorrentino, MD<br />

Chicago, IL<br />

Thomas A. Sos, MD<br />

New York, NY<br />

James R. Sowers, MD, F<strong>ASH</strong><br />

Columbia, MO<br />

Lesley A. Stevens, MD, MS<br />

Boston, MA<br />

Allan D. Struthers, MD<br />

Dundee, United Kingdom<br />

Laura P. Svetkey, MD<br />

Durham, NC<br />

Sandra J. Taler, MD, F<strong>ASH</strong><br />

Rochester, MN<br />

Ting Tao, MD<br />

Shanghai, China<br />

34


<strong>2011</strong> <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> Annual Meeting & Expostion – <strong>Program</strong> at a Glance<br />

Day – Date – Time Pathobiology Translational Therapy Special Sessions Joint Sessions Debates/Meet the Pr<strong>of</strong>essor Innovations Theater Satellite Symposia<br />

Saturday, May 21, <strong>2011</strong><br />

8:30 AM to 3:00 PM<br />

Saturday, May 21, <strong>2011</strong> Pavilion Hours – Open 4:30 PM to 7:30 PM Posters on Display – 4:30 PM to 7:30 PM; Poster Viewing – 6:00 PM to 7:00 PM<br />

Americas Hall, 3rd Floor<br />

<strong>Hypertension</strong><br />

Highlights <strong>2011</strong><br />

East Ballroom, 3rd Floor<br />

Saturday, May 21, <strong>2011</strong><br />

3:15 PM to 4:15 PM<br />

Membership Meeting<br />

<strong>ASH</strong> Members Only<br />

Saturday, May 21, <strong>2011</strong><br />

4:30 PM to 6:00 PM<br />

Trianon Rendezvous, 3rd Floor<br />

Young Investigator<br />

Competition Award<br />

Joint Session – <strong>American</strong><br />

Heart Association’s Council for<br />

High Blood Pressure Research<br />

Saturday, May 21, <strong>2011</strong><br />

6:30 PM to 7:30 PM<br />

Sunday, May 22, <strong>2011</strong><br />

8:00 AM to 12:30 PM<br />

Trianon Rendezvous, 3rd Floor<br />

Genomics and <strong>Hypertension</strong><br />

Beekman Parlor, 2nd Floor<br />

Joint Session – Preventive<br />

Cardiovascular Nurses<br />

Association<br />

Sutton South, 2nd Floor<br />

Joint Session – Association for<br />

Research into Atterial Structure<br />

and Physiology and North<br />

<strong>American</strong> Artery<br />

Regent Parlor, 2nd Floor<br />

Joint Session – National Lipid<br />

Association/<strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> Preventive Cardiology<br />

Sutton Center, 2nd Floor<br />

Saturday, May 21, <strong>2011</strong> 6:00 PM to 7:30 PM Opening Reception – <strong>Hypertension</strong> Resource Pavilion<br />

Americas Hall, 3rd Floor<br />

Sunday, May 22, <strong>2011</strong> 10:00 AM to 1:00 PM <strong>Hypertension</strong> Resource Pavilion Opens – 11:30 AM to 1:00 PM Brunch<br />

Americas Hall, 3rd Floor<br />

<strong>Hypertension</strong> for the<br />

Primary Care Clinician <strong>2011</strong><br />

Sutton North, 2nd Floor<br />

Innovations Theater<br />

Rhinelander Gallery, 2nd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

9:30 AM to 11:00 AM<br />

Joint Session – International<br />

Pediatric <strong>Hypertension</strong><br />

Association<br />

Sutton North, 2nd Floor<br />

Joint Session – China Social<br />

Worker’s Association Vascular<br />

Protection Committee<br />

Sutton Center, 2nd Floor<br />

Joint Session –<br />

<strong>Hypertension</strong> Canada<br />

Sutton South, 2nd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

11:00 AM to 12:00 PM<br />

Joint Session –<br />

Inter-<strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong><br />

Regent Parlor, 2nd Floor<br />

Meet the Pr<strong>of</strong>essor –<br />

How to Write a 12 Page Grant<br />

Beekman Parlor, 2nd Floor<br />

Meet the Pr<strong>of</strong>essor –<br />

Understanding Statistics in<br />

Clinical Research<br />

Sutton North, 2nd Floor<br />

Meet the Pr<strong>of</strong>essor –<br />

How to Develop an Abstract/<br />

Lecture<br />

Sutton Center, 2nd Floor<br />

Debate –<br />

Is it Blood Pressure Variablility<br />

or Average Daily Blood<br />

Pressure that Best Predicts<br />

Stroke<br />

Sutton South, 2nd Floor<br />

Debate –<br />

Surgical Intervention for Renal<br />

Artery Stenosis is Indicated<br />

Regent Parlor, 2nd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

12:00 PM to 1:00 PM<br />

West Ballroom, 3rd Floor<br />

Innovations Theater<br />

Rhinelander Gallery, 2nd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

1:15 PM to 3:00 PM<br />

Plenary Session I<br />

East Ballroom, 3rd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

3:30 PM to 5:15 PM<br />

Aldosterone<br />

Mercury Ballroom, 3rd Floor<br />

<strong>Hypertension</strong> in Patients<br />

With Chronic Kidney<br />

Disease<br />

East Ballroom, 3rd Floor<br />

Comprehensive Multi-<br />

Level Interventions for<br />

<strong>Hypertension</strong> Management<br />

in High-Risk Groups<br />

West Ballroom, 3rd Floor<br />

Control <strong>of</strong> <strong>Hypertension</strong> is<br />

Leaving the Office: The Role<br />

<strong>of</strong> Home Blood Pressure and<br />

Telemedicine<br />

Trianon Ballroom, 3rd Floor<br />

Joint Session –<br />

International <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong> in Blacks<br />

Trianon Rendezvous, 3rd Floor<br />

Sunday, May 22, <strong>2011</strong> 5:30 PM to 6:30 PM High Tea and Poster Viewing<br />

Americas Hall, 3rd Floor<br />

Sunday, May 22, <strong>2011</strong><br />

5:30 PM to 6:30 PM<br />

Innovations Theater<br />

Rhinelander Gallery, 2nd Floor<br />

Monday, May 23, <strong>2011</strong> 10:00 AM to 1:30 PM <strong>Hypertension</strong> Resource Pavilion Opens – Lunch in Pavilion 12:00 PM to 1:15 PM<br />

Americas Hall, 3rd Floor<br />

Monday, May 23, <strong>2011</strong><br />

6:00 AM to 7:30 AM<br />

Symposia<br />

Trianon Ballroom, 3rd Floor<br />

Monday, May 23, <strong>2011</strong><br />

8:00 AM to 10:00 AM<br />

Off-Target Cardiovascular<br />

Effects <strong>of</strong> Non-<br />

Cardiovascular Drugs<br />

New Insights into the Role<br />

<strong>of</strong> Uric Acid in <strong>Hypertension</strong><br />

Devices and Surgical<br />

Ablation for Refractory<br />

<strong>Hypertension</strong><br />

Joint Session –<br />

National Kidney Foundation<br />

Mercury Ballroom, 3rd Floor<br />

East Ballroom, 3rd Floor<br />

West Ballroom, 3rd Floor<br />

Trianon Rendezvous, 3rd Floor<br />

Monday, May 23, <strong>2011</strong><br />

10:30 AM to 12:00 PM<br />

Immune Mechanisms in<br />

<strong>Hypertension</strong><br />

Management <strong>of</strong> Elevated<br />

Blood Pressure in the<br />

Hospital Setting<br />

Management <strong>of</strong><br />

<strong>Hypertension</strong> in Diabetics<br />

and Chronic Kidney Disease<br />

Hyperkalemia Management<br />

in High Risk Patients: New<br />

Evidence-Based Approaches<br />

Joint Session –<br />

European <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong><br />

Mercury Ballroom, 3rd Floor<br />

East Ballroom, 3rd Floor<br />

West Ballroom, 3rd Floor<br />

Trianon Ballroom, 3rd Floor<br />

Trianon Rendezvous, 3rd Floor<br />

Monday, May 23, <strong>2011</strong><br />

11:45 AM to 12:15 PM<br />

Debate<br />

Are Elevated Potassium Levels<br />

Really a Concern<br />

Trianon Ballroom, 3rd Floor<br />

Monday, May 23, <strong>2011</strong><br />

1:30 PM to 4:00 PM<br />

Monday, May 23, <strong>2011</strong><br />

4:30 PM to 5:00 PM<br />

Tuesday, May 24, <strong>2011</strong><br />

8:15 AM to 9:30 AM<br />

Tuesday, May 24, <strong>2011</strong><br />

10:00 AM to 11:30 AM<br />

Salt-Sensitive Mechanisms<br />

<strong>of</strong> <strong>Hypertension</strong><br />

Plenary Session II<br />

Monday, May 23, <strong>2011</strong> 4:00 PM to 5:30 PM <strong>Hypertension</strong> Resource Pavilion Opens – High Tea and Poster Viewing 4:30 PM to 5:30 PM<br />

Americas Hall, 3rd Floor<br />

Integrated Cardiovascular<br />

Disease Guidelines and<br />

Implementation<br />

Nutrition and<br />

Cardiovascular Prevention<br />

East Ballroom, 3rd Floor<br />

Late-Breaking Clinical Trials<br />

West Ballroom, 3rd Floor<br />

Debate<br />

The Dominant Contributor<br />

to Systemic <strong>Hypertension</strong> is:<br />

Sympathetic Nervous System<br />

not the RAAS; or Activation<br />

<strong>of</strong> the Intrarenal RAAS not<br />

the SNS<br />

Beekman Parlor, 2nd Floor<br />

Debate<br />

<strong>Hypertension</strong> is a Disorder <strong>of</strong><br />

the Kidney<br />

Sutton North, 2nd Floor<br />

Sutton North, 2nd Floor<br />

Sutton Center, 2nd Floor<br />

Beekman Parlor, 2nd Floor


<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc.<br />

<strong>2011</strong> Annual Scientific Meeting and Exposition<br />

<strong>2011</strong> <strong>Program</strong><br />

at a Glance<br />

Hilton New York<br />

Saturday, May 21, <strong>2011</strong> – Tuesday, May 24, <strong>2011</strong>


<strong>2011</strong> <strong>ASH</strong> Faculty continued<br />

Addison A. Taylor, MD, PhD,<br />

F<strong>ASH</strong><br />

Houston, TX<br />

Jens Titze, MD<br />

Erlangen, Germany<br />

Sheldon W. Tobe, MD, F<strong>ASH</strong><br />

Toronto, Canada<br />

Robert D. Toto, MD<br />

Dallas, TX<br />

Rhian M. Touyz, MD, PhD<br />

Ottawa, Canada<br />

Raymond R. Townsend, MD<br />

Philadelphia, PA<br />

Joseph A. Vassalotti, MD<br />

New York, NY<br />

Ronald G. Victor, MD<br />

Los Angeles, CA<br />

Hongyu Wang, MD, PhD<br />

Beijing, China<br />

R. Clinton Webb, PhD<br />

Augusta, GA<br />

David J. Webb, MD<br />

Edinburgh, United Kingdom<br />

Michael A. Weber, MD, F<strong>ASH</strong><br />

New York, NY<br />

Alan B. Weder, MD<br />

Ann Arbor, MI<br />

Myron H. Weinberger, MD<br />

Indianapolis, IN<br />

Matthew R. Weir, MD, F<strong>ASH</strong><br />

Baltimore, MD<br />

Adam Whaley-Connell, DO,<br />

F<strong>ASH</strong><br />

Columbia, MO<br />

Andrew Whelton, MD<br />

Baltimore, MD<br />

William B. White, MD, F<strong>ASH</strong><br />

Farmington, CT<br />

Ian B. Wilkinson, MD<br />

Cambridge, United Kingdom<br />

Bryan Williams, MD<br />

Leicester, United Kingdom<br />

Gordon H. Williams, MD<br />

Boston, MA<br />

Peter W. F. Wilson, MD<br />

Atlanta, GA<br />

Nathan D. Wong, PhD, MPH<br />

Irvine, CA<br />

Martin S. Zand, MD<br />

Rochester, NY<br />

37


<strong>Program</strong> Color Key<br />

The pages <strong>of</strong> this <strong>Program</strong> <strong>Book</strong> are color-coded to match the<br />

<strong>Program</strong> at a Glance (pages 35–36) and serve as a quick, identifiable<br />

reference <strong>of</strong> the type <strong>of</strong> educational activity or event taking place.<br />

Scientific Sessions*<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

<strong>Hypertension</strong> Highlights <strong>2011</strong><br />

Special Event<br />

Meet the Pr<strong>of</strong>essor Sessions<br />

<strong>Hypertension</strong> for the Primary Care Clinician<br />

Debates<br />

Poster Sessions<br />

Satellite Symposia<br />

<strong>Hypertension</strong> Resource Pavilion<br />

The <strong>ASH</strong> Twenth-Sixth Annual Scientific Meeting is<br />

organized around three (3) concurrent themes:<br />

• Pathobiology <strong>of</strong> <strong>Hypertension</strong><br />

• Translational Issues in <strong>Hypertension</strong><br />

• Therapy <strong>of</strong> <strong>Hypertension</strong><br />

Sessions in each <strong>of</strong> the three (3) themes (or tracks) are labeled<br />

throughout the <strong>Program</strong> <strong>Book</strong> to be easily identifiable.


<strong>2011</strong><br />

<strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong><br />

<strong>Program</strong>


MAY 21<br />

Saturday Morning<br />

<strong>Hypertension</strong> Highlights <strong>2011</strong><br />

8:00 AM – 3:00 PM • East Ballroom • Third Floor<br />

Part I:<br />

Co-Chairs: Henry R. Black, MD, F<strong>ASH</strong>, New York, NY and<br />

Michael A. Weber, MD, F<strong>ASH</strong>, New York, NY<br />

8:00 AM Breakfast<br />

8:30 AM Cardiovascular Effects <strong>of</strong> Anti-Diabetic Drugs<br />

Nancy J. Brown, MD, Nashville, TN<br />

9:00 AM Role <strong>of</strong> the Kidney in Angiotensin II <strong>Hypertension</strong><br />

Steven D. Crowley, PhD, Durham, NC<br />

9:30 AM Neurohormonal Assessment in the Diagnosis and<br />

Management <strong>of</strong> <strong>Hypertension</strong><br />

Ronald G. Victor, MD, Los Angeles, CA<br />

10:00 AM Break<br />

Part II:<br />

10:30 AM Panel Discussion: <strong>Hypertension</strong> and Obesity in<br />

Adolescence: Epidemiology, Nutritional Aspects,<br />

Evaluation and Management<br />

Moderator: Bonita Falkner, MD, F<strong>ASH</strong>, Philadelphia,<br />

PA<br />

Panel Discussion Participants:<br />

Donald L. Batisky, MD, Atlanta, GA<br />

Joseph T. Flynn, MD, F<strong>ASH</strong>, Seattle, WA and<br />

Robert F. Kushner, MD, Chicago, IL<br />

11:15 AM Partnership with the Patient to Improve Blood<br />

Pressure Control and the Role <strong>of</strong> the <strong>Hypertension</strong><br />

Specialist in the “Medical Home”<br />

Moderator: Elijah Saunders, MD, F<strong>ASH</strong>, Baltimore,<br />

MD<br />

Joel Handler, MD, Anaheim, CA and<br />

Nancy Houston Miller, RN, BSN, Palo Alto, CA<br />

12:15 PM Lunch<br />

Part III:<br />

1:00 PM Panel Discussion: Resistant <strong>Hypertension</strong>:<br />

Pathophysiology, Evaluation, and New/Old<br />

Treatment Considerations<br />

Moderator: C. Venkata S. Ram, MD, F<strong>ASH</strong>, Dallas, TX<br />

Panel Discussion Participants:<br />

Michael W. Brands, PhD, Augusta, GA<br />

John D. Bisognano, MD, PhD, F<strong>ASH</strong>, Rochester, NY<br />

Domenic A. Sica, MD, Richmond, VA and<br />

Gordon H. Williams, MD, Boston, MA<br />

2:15 PM Complementary and Alternative Therapies in<br />

<strong>Hypertension</strong><br />

Moderator: Robert A. Phillips, MD, PhD, F<strong>ASH</strong>,<br />

Worcester, MA<br />

Panel Discussion Participants:<br />

Brent M. Egan, MD, F<strong>ASH</strong>, Charleston, SC and<br />

Matthew Sorrentino, MD, Chicago, IL<br />

40


Saturday Afternoon MAY 21<br />

<strong>ASH</strong> Membership Meeting<br />

3:15 PM – 4:15 PM • Trianon Rendezvous • Third Floor<br />

<strong>ASH</strong> Annual Membership Meeting<br />

41


MAY 21<br />

Sessions<br />

Saturday Afternoon<br />

4:30 PM – 6:00 PM • Beekman Parlor • Second Floor<br />

Genomics and <strong>Hypertension</strong><br />

Co-Chairs: Theodore W. Kurtz, MD, San Francisco, CA and<br />

Alan B. Weder, MD, Ann Arbor, MI<br />

4:30 PM Pharmacogenetics and Cardiovascular Disease<br />

Nita A. Limdi, PharmD, PhD, MSPH, Birmingham, AL<br />

5:00 PM Genomics <strong>of</strong> Experimental <strong>Hypertension</strong>:<br />

Translation to Humans<br />

Theodore W. Kurtz, MD<br />

5:30 PM Antihypertensive Drug Pharmacogenomics<br />

Julie A. Johnson, PharmD, Gainesville, FL<br />

42


Saturday Afternoon MAY 21<br />

Sessions<br />

4:30 PM – 6:00 PM • Sutton North • Second Floor<br />

Advancements in the Pathophysiology <strong>of</strong><br />

<strong>Hypertension</strong>: Some Novel Concepts<br />

Held in Partnership with the <strong>American</strong> Heart Association’s Council<br />

for High Blood Pressure Research (HBPR)<br />

Co-Chairs: Phyllis August, MD, MPH, New York, NY and<br />

Rhian M. Touyz, MD, PhD, Ottawa, Canada<br />

4:30 PM Overview<br />

Rhian M. Touyz, MD, PhD<br />

4:40 PM Pathophysiology <strong>of</strong> <strong>Hypertension</strong> in Preeclampsia:<br />

Novel Concepts<br />

Joey P. Granger, PhD, Jackson, MS<br />

5:06 PM Vascular Function, <strong>Hypertension</strong> and Erectile<br />

Dysfunction: Novel Mechanisms<br />

R. Clinton Webb, PhD, Augusta, GA<br />

5:32 PM Obesity-Related <strong>Hypertension</strong>: Basic Concepts and<br />

Clinical Implications<br />

John E. Hall, PhD, Jackson, MS<br />

43


MAY 21<br />

Sessions<br />

Saturday Afternoon<br />

4:30 PM – 6:00 PM • Sutton Center • Second Floor<br />

Cardiovascular Risk Prevention<br />

Held in Partnership with the <strong>American</strong> <strong>Society</strong> <strong>of</strong> Preventive<br />

Cardiology (ASPC) and the National Lipid Association (NLA)<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

Peter W. F. Wilson, MD, Atlanta, GA<br />

4:30 PM Welcoming Remarks<br />

Peter W. F. Wilson, MD<br />

4:40 PM Prevention Strategy and National Healthcare<br />

Thomas A. Pearson, MD, PhD, MPH, Rochester, NY<br />

5:00 PM National Health Forum Initiatives: Dollars and<br />

Cents<br />

Keith C. Ferdinand, MD, F<strong>ASH</strong>, Atlanta, GA<br />

5:20 PM Aggressive Medical Management versus<br />

Intervention: An Uphill Road to Policy Change<br />

William E. Boden, MD, Buffalo, NY<br />

5:40 PM Leadership Panel Discussion<br />

George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL, Michael H.<br />

Davidson, MD, Chicago, IL and Nathan D. Wong, PhD,<br />

MPH, Irvine, CA<br />

Questions and Answers<br />

44


Saturday Afternoon MAY 21<br />

Sessions<br />

4:30 PM – 6:00 PM • Sutton South • Second Floor<br />

Advocating for Adherence to Better Control<br />

<strong>Hypertension</strong><br />

Held in Partnership with the Preventive Cardiovascular Nurses<br />

Association (PCNA)<br />

Co-Chairs: Nancy Artinian, PhD, RN, Detroit, MI and<br />

Barry L. Carter, PharmD, Iowa City, IA<br />

4:30 PM Enhancing Adherence in Ethically-Diverse<br />

Populations<br />

Gbenga Ogedegbe, MD, MPH, MS, F<strong>ASH</strong>, New York,<br />

NY and Antoinette Schoenthaler, EdD, New York, NY<br />

4:52 PM From Adherence to Advocacy: The Need to Reduce<br />

Sodium<br />

Suzanne Hughes, RN, MSN, Akron, OH<br />

5:14 PM Adherence and Persistence with Medications:<br />

The <strong>ASH</strong> Position<br />

Nancy Houston Miller, RN, BSN, Palo Alto, CA<br />

5:36 PM Practical Tips to Assess and Promote Adherence in<br />

Clinical Practice<br />

Lynne T. Braun, PhD, CNP, Chicago, IL<br />

45


MAY 21<br />

Sessions<br />

Saturday Afternoon<br />

4:30 PM – 6:00 PM • Regent Parlor • Second Floor<br />

Arterial Stiffness: A Paradigm Shift in<br />

Understanding the Increased Cardiovascular Risk<br />

Associated with Aging and Chronic Disease<br />

Held in Partnership with the Association for Research into Arterial<br />

Structure and Physiology (ARTERY) and North <strong>American</strong> Artery<br />

(NAA)<br />

Co-Chairs: John R. Cockcr<strong>of</strong>t, MD, Cardiff, United Kingdom and<br />

Stanley S. Franklin, MD, F<strong>ASH</strong>, Los Angeles, CA<br />

4:30 PM Chronic Obstructive Pulmonary Disease Arterial<br />

Stiffness and Cardiovascular Disease<br />

John R. Cockcr<strong>of</strong>t, MD<br />

4:52 PM Vasculitides Arterial Stiffness and Cardiovascular<br />

Disease<br />

Ian B. Wilkinson, MD, Cambridge, United Kingdom<br />

5:14 PM Is Vascular Aging Inevitable<br />

Edward G. Lakatta, MD, Baltimore, MD<br />

5:36 PM Pulse Wave Analysis in Subjects with Chronic<br />

Kidney Disease<br />

Raymond R. Townsend, MD, Philadelphia, PA<br />

46


Saturday Afternoon MAY 21<br />

Sessions<br />

4:30 PM – 6:00 PM • Trianon Rendezvous • Third Floor<br />

Young Investigator-in-Training Abstract<br />

Competition<br />

Moderator:<br />

Judges:<br />

Addison A. Taylor, MD, PhD, F<strong>ASH</strong>, Houston, TX<br />

Stephen R. Daniels, MD, PhD, F<strong>ASH</strong>, Aurora, CO,<br />

Thomas D. Giles, MD, F<strong>ASH</strong>, New Orleans, LA,<br />

Lawrence R. Krak<strong>of</strong>f, MD, New York, NY,<br />

Susanne B. Nicholas, MD, PhD, MPH, Los Angeles, CA,<br />

and Myron H. Weinberger, MD, Indianapolis, IN<br />

4:30 PM OR-1: Waist Hip Ratio vs Body Mass Index as<br />

Predictors <strong>of</strong> Endothelial Dysfunction<br />

Arantxa Rodriguez, Rosa Fabregate, Martin Fabregate,<br />

Susana Tello, Angelica Fernandez, Asuncion Guerri,<br />

Nuria De la Torre, Jose Saban‐Ruiz. Ramon y Cajal<br />

Hospital, Madrid, ES.<br />

4:42 PM OR-2: M-Atrial Natriuretic Peptide, a Novel Anti-<br />

Hypertensive Therapeutic Peptide, Is Markedly<br />

Resistant to In Vitro Degradation<br />

Paul M. McKie, Alessandro Cataliotti, Tomoko Ichiki,<br />

S. Jeson Sangaralingham, Valentina Cannone, John C.<br />

Burnett, Jr. Mayo Clinic, Rochester, MN, US.<br />

4:54 PM OR-3: Outcomes with Atenolol or Other β-Blockers:<br />

Network and Bayesian Meta-Analyses <strong>of</strong> Clinical<br />

Trials in <strong>Hypertension</strong><br />

W. Kurtis Childers†, 1 William J. Elliott, 1 Sanjib Basu, 2<br />

Peter M. Meyer. 2 1 Pacific Northwest University <strong>of</strong><br />

Health Sciences, Yakima, WA, US; 2 RUSH Medical<br />

College, Chicago, IL, US.<br />

5:06 PM OR-4: Role <strong>of</strong> Renal DJ-1 in the Regulation <strong>of</strong><br />

Oxidative Stress<br />

Santiago Cuevas Gonzalez, Yanrong Zhang, Yu Yang,<br />

Laureano D. Asico, Pedro A. Jose, Ines Armando.<br />

Children’s National Medical Center, George<br />

Washington University, Washington, DC, US.<br />

5:18 PM OR-5: Adiposity, Metabolic and Dietary Risk Factors<br />

Associated with Prehypertension in Black and White<br />

Adolescent Males: A Cross-Sectional Study<br />

Samip J. Parikh, Haidong Zhu, Norman K. Pollock,<br />

Inger Stallmann-Jorgensen, Gutin Bernard, Yanbin<br />

Dong. Medical College <strong>of</strong> Georgia, Augusta, GA, US.<br />

47


MAY 21<br />

Posters<br />

Saturday Evening<br />

Posters will be displayed in the Second Floor Promenade.<br />

Saturday, May 21, <strong>2011</strong><br />

Posters on Display: 4:30 PM – 7:30 PM • Poster Viewing: 6:00 PM – 7:00 PM<br />

Adolescent <strong>Hypertension</strong> and Obesity.............................. (PO-1 – PO-5)<br />

Antiatherosclerotic Drugs................................................... (PO-6 – PO-7)<br />

Cardiac Structure and Function/Imaging....................... (PO-8 – PO-10)<br />

Comprehensive Multi-Level Interventions for<br />

<strong>Hypertension</strong> Management in High-Risk Groups......(PO-11 – PO-30)<br />

Endothelial Function.......................................................(PO-31 – PO-45)<br />

Epidemiology/Special Populations................................(PO-46 – PO-78)<br />

Immune Mechanisms in <strong>Hypertension</strong>........................(PO-79 – PO-82)<br />

Metabolic Syndrome (Diabetes/Glycemic Control;<br />

Dysglycemic Drugs; Insulin Resistance).....................(PO-83 – PO-102)<br />

New Insights into the Role <strong>of</strong> Uric Acid<br />

in <strong>Hypertension</strong>............................................................(PO-103 – PO-104)<br />

Pediatric <strong>Hypertension</strong>...............................................(PO-105 – PO-111)<br />

Risk Factors (Lipids)....................................................(PO-112 – PO-115)<br />

Stroke.............................................................................(PO-117 – PO-119)<br />

Vascular Injury/Inflammation and Remodeling......(PO-120 – PO-123)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

48


Sunday Morning MAY 22<br />

Sessions<br />

8:00 AM – 12:30 PM • West Ballroom • Third Floor<br />

<strong>Hypertension</strong> for the Primary Care Clinician <strong>2011</strong><br />

7:30 AM Breakfast<br />

8:00 AM to 9:00 AM<br />

The Management <strong>of</strong> the Hypertensive Patient<br />

Before and After Surgery<br />

Co-Chairs: Jan N. Basile, MD, F<strong>ASH</strong>, Charleston, SC and<br />

F. Wilford Germino, MD, F<strong>ASH</strong>, Orland Park, IL<br />

8:00 AM Case Presentation<br />

F. Wilford Germino, MD, F<strong>ASH</strong><br />

8:10 AM Pre-operative Evaluation <strong>of</strong> the Patient with<br />

<strong>Hypertension</strong><br />

James B. Froehlich, MD, MPH, Ann Arbor, MI<br />

8:35 AM Peri-operative Management <strong>of</strong> the Hospitalized<br />

Patient with <strong>Hypertension</strong><br />

John D. Bisognano, MD, PhD, F<strong>ASH</strong>, Rochester, NY<br />

9:00 AM to 10:00 AM<br />

A Systems Approach to Optimize Blood Pressure<br />

Control<br />

Co-Chairs: Paula T. Einhorn, MD, MS, Bethesda, MD and Gbenga<br />

Ogedegbe, MD, MPH, MS, F<strong>ASH</strong>, New York, NY<br />

9:00 AM Exporting Lifestyle Modification into Your Practice<br />

Laura P. Svetkey, MD, Durham, NC<br />

9:20 AM Electronic Medical Records and the <strong>Hypertension</strong><br />

Initiative in the Carolinas<br />

Brent M. Egan, MD, F<strong>ASH</strong>, Charleston, SC<br />

9:40 AM A Team Based Approach to Blood Pressure Control<br />

Barry L. Carter, PharmD, Iowa City, IA<br />

10:00 AM Break<br />

10:15 AM to 11:15 AM<br />

Evaluation <strong>of</strong> Resistant <strong>Hypertension</strong><br />

Co-Chairs: Louis Kuritzky, MD, Gainesville, FL and<br />

Samuel J. Mann, MD, New York, NY<br />

10:15 AM Out <strong>of</strong> Office Monitoring to Rule Out Resistant<br />

<strong>Hypertension</strong><br />

Angela L. Brown, MD, St. Louis, MO<br />

continued…<br />

49


MAY 22<br />

Sunday morning<br />

Sessions continued<br />

10:30 AM Outpatient Evaluation for Secondary Causes <strong>of</strong><br />

Resistant <strong>Hypertension</strong><br />

Emmanuel Bravo, MD, Cleveland, OH<br />

10:55 AM Treatment <strong>of</strong> Resistant <strong>Hypertension</strong>:<br />

Tricks <strong>of</strong> the Trade<br />

William J. Elliott, MD, PhD, F<strong>ASH</strong>, Yakima, WA<br />

11:15 AM Panel Discussion:<br />

How Has the Management <strong>of</strong> <strong>Hypertension</strong> in<br />

Primary Care Changed Since JNC 7<br />

Chair: Michael J. Bloch, MD, F<strong>ASH</strong>, Reno, NV<br />

Panel Discussion Participants:<br />

George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL,<br />

Jan N. Basile, MD, F<strong>ASH</strong>, Charleston, SC,<br />

Angela L. Brown, MD, St. Louis, MO and<br />

Leonard M. Fromer, MD, Los Angeles, CA<br />

This Live activity, <strong>Hypertension</strong> for the Primary Care Clinician <strong>2011</strong>,<br />

has been reviewed and is acceptable for up to 4.25 Prescriptive credits by<br />

the <strong>American</strong> Academy <strong>of</strong> Family Physicians. Physicians should claim<br />

only the credit commensurate with the extent <strong>of</strong> their participation in<br />

the activity.<br />

50


Sunday Morning MAY 22<br />

Sessions<br />

9:00 AM – 10:30 AM • Sutton North • Second Floor<br />

The Role <strong>of</strong> Neurohumoral and Vasoactive<br />

Substances in <strong>Hypertension</strong><br />

Held in Partnership with the International Pediatric <strong>Hypertension</strong><br />

Association (IPHA)<br />

Co-Chairs: Donald L. Batisky, MD, Atlanta, GA and<br />

Jay N. Cohn, MD, Minneapolis, MN<br />

9:00 AM Effects <strong>of</strong> Endothelin Blockade on Blood Pressure:<br />

Pro and Con<br />

David M. Pollock, PhD, Augusta, GA<br />

9:30 AM The Interplay <strong>of</strong> Race/Ethnicity, Inflammation<br />

and Elevated Blood Pressure in Children and<br />

Adolescents<br />

Marc B. Lande, MD, MPH, Rochester, NY<br />

10:00 AM Dopamine, the Kidney and <strong>Hypertension</strong><br />

Pedro A. Jose, MD, Washington, DC<br />

51


MAY 22<br />

Sessions<br />

Sunday Morning<br />

9:00 AM – 10:30 AM • Regent Parlor • Second Floor<br />

Renin-Angiotensin System in <strong>Hypertension</strong>:<br />

Regulation and Consequences<br />

Held in Partnership with the Inter-<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong><br />

(I<strong>ASH</strong>)<br />

Co-Chairs: Haralambos Gavras, MD, Boston, MA and<br />

L. Gabriel Navar, PhD, New Orleans, LA<br />

9:00 AM Introduction: The Intratubular RAS in <strong>Hypertension</strong><br />

L. Gabriel Navar, PhD<br />

9:22 AM Role <strong>of</strong> the Transcription Factor ETS-1 as Mediator<br />

<strong>of</strong> Angiotensin II Induced End-Organ Injury<br />

Edgar A. Jaimes, MD, Birmingham, AL<br />

9:44 AM <strong>Hypertension</strong>, Insulin Resistance and Oxidative<br />

Stress<br />

Leopoldo Raij, MD, F<strong>ASH</strong>, Miami, FL<br />

10:06 AM Therapeutic Efficacy <strong>of</strong> New Renin Inhibitors<br />

Luis Juncos, MD, Córdoba, Argentina<br />

52


Sunday Morning MAY 22<br />

Sessions<br />

9:00 AM – 10:40 AM • Sutton Center • Second Floor<br />

The 3rd <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>/China<br />

Social Worker’s Association Vascular Protection<br />

Committee Session on Early Vascular Disease<br />

Detection and Management: Experience from China<br />

Co-Chairs: Suzanne Oparil, MD, F<strong>ASH</strong>, Birmingham, AL and<br />

Hongyu Wang, MD, PhD, Beijing, China<br />

9:00 AM Chinese Guidelines for Early Vascular Disease<br />

Detection <strong>2011</strong>: Experience from China<br />

Hongyu Wang, MD, PhD<br />

9:20 AM Role <strong>of</strong> Cardiometabolic Syndrome and Related<br />

Vascular Disease in Chinese Elderly<br />

Ting Tao, MD, Shanghai, China<br />

9:40 AM Epidemiology <strong>of</strong> <strong>Hypertension</strong> and Peripheral<br />

Vascular Disease in China<br />

Jianfang Luo, MD, Guangzhou, China<br />

10:00 AM Carotid IMT Examination for Atherosclerosis<br />

Screening in Diabetes<br />

Yuan Guo, MD, MS, Beijing, China<br />

10:20 AM Arterial Stiffness Parameters Integrated for Vascular<br />

Health Evaluation in Hypertensive Patients<br />

Tianhu Liu, MD, Chengdu, China<br />

53


MAY 22<br />

Sessions<br />

Sunday Morning<br />

9:00 AM – 10:30 AM • Sutton South • Second Floor<br />

Overcoming Clinical Inertia: Changing Practice<br />

Paradigms on Both Sides <strong>of</strong> the 49th Parallel<br />

Held in Partnership with <strong>Hypertension</strong> Canada<br />

Co-Chairs: Ross Feldman, MD, London, Canada and<br />

Alan H. Gradman, MD, F<strong>ASH</strong>, Pittsburgh, PA<br />

9:00 AM Introduction: Definitions and Scope <strong>of</strong> the Issue<br />

Joel M. Neutel, MD, F<strong>ASH</strong>, Tustin, CA<br />

9:10 AM Clinic Focused Educational Interventions to<br />

Improve Blood Pressure Control: Using the Heart<br />

and Stroke <strong>Hypertension</strong> Clinic Model as the<br />

Paradigm<br />

Sheldon W. Tobe, MD, F<strong>ASH</strong>, Toronto, Canada<br />

9:35 AM Simplifying Treatment Algorithms as a Means <strong>of</strong><br />

Reducing Clinical Inertia<br />

Ross Feldman, MD<br />

10:00 AM US Approaches for Guidelines Implementation<br />

William C. Cushman, MD, F<strong>ASH</strong>, Memphis, TN<br />

10:10 AM Implementation and Impact <strong>of</strong> the Canadian<br />

<strong>Hypertension</strong> Education <strong>Program</strong><br />

Norman R.C. Campbell, MD, Calgary, Canada<br />

10:20 AM Questions and Answers<br />

54


Sunday Morning MAY 22<br />

Posters<br />

Posters will be displayed in the Second Floor Promenade.<br />

Sunday, May 22, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 6:30 PM • Poster Viewing: 5:30 PM – 6:30 PM<br />

Featured Posters<br />

Blood Pressure Measurement/Monitoring......................(FP-1 – FP-4)<br />

Adolescent <strong>Hypertension</strong>..................................................(FP-5 – FP-8)<br />

Aldosterone and Anti-Aldosterone Agents..............(PO-124 – PO-130)<br />

Antihypertensive Drugs and Pharmacology............(PO-131 – PO-157)<br />

Clinical Trials................................................................(PO-158 – PO-184)<br />

Coronary Artery Disease............................................(PO-185 – PO-191)<br />

Genetics/Gene Therapy/Proteomics..........................(PO-192 – PO-198)<br />

Heart Failure/Hypertrophy<br />

(Diastolic Dysfunction)...............................................(PO-199 – PO-216)<br />

<strong>Hypertension</strong> in Patients with Chronic<br />

Kidney Disease.............................................................(PO-217 – PO-226)<br />

Kidney and <strong>Hypertension</strong>...........................................(PO-227 – PO-242)<br />

Off-Target Cardiovascular Effects <strong>of</strong><br />

Non-Cardiovascular Drugs........................................(PO-243 – PO-244)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

55


MAY 22<br />

Debates<br />

Sunday Morning<br />

11:00 AM – 12:00 PM<br />

Sutton South • Second Floor<br />

Debate: Is it Blood Pressure Variability or Average<br />

Daily Blood Pressure that Best Predicts Stroke<br />

Moderator: William B. White, MD, F<strong>ASH</strong>, Farmington, CT<br />

11:00 AM Blood Pressure Variability<br />

Peter M. Rothwell, MD, Oxford, United Kingdom<br />

11:20 AM Average Daily Blood Pressure<br />

Eoin O’Brien, MD, Dublin, Ireland<br />

11:40 AM Rebuttal<br />

11:55 AM Questions and Answers<br />

Regent Parlor • Second Floor<br />

Debate: Surgical Intervention for Renal Artery<br />

Stenosis is Indicated<br />

Moderator: Bryan Williams, MD, Leicester, United Kingdom<br />

11:00 AM Yes: Thomas A. Sos, MD, New York, NY<br />

11:20 AM No: Lance D. Dworkin, MD, Providence, RI<br />

11:40 AM Rebuttal<br />

11:55 AM Questions and Answers<br />

56


Sunday Morning MAY 22<br />

Special Sessions<br />

11:00 AM – 12:00 PM<br />

Meet the Pr<strong>of</strong>essor Sessions<br />

Beekman Parlor • Second Floor<br />

How to Write a 12 Page Grant<br />

David Harder, MD, PhD, Milwaukee, WI<br />

Sutton North • Second Floor<br />

Understanding Statistics in Clinical Research<br />

Richard H. Grimm, Jr., MD, PhD, Minneapolis, MN<br />

Sutton Center • Second Floor<br />

How to Develop an Abstract/Lecture<br />

David G. Harrison, MD, Atlanta, GA<br />

57


MAY 22<br />

Plenary Session I<br />

Sunday Afternoon<br />

1:15 PM – 3:00 PM • East Ballroom • Third Floor<br />

Plenary Session I<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

William B. White, MD, F<strong>ASH</strong>, Farmington, CT<br />

1:15 PM President’s Opening Address<br />

1:30 PM Keynote Lecture: Blood Pressure in Obesity<br />

F. Xavier Pi‐Sunyer, MD, MPH, New York, NY<br />

2:00 PM Cardiovascular Risk and Risk Reduction in Children<br />

and Adolescents<br />

Rae‐Ellen W. Kavey, MD, MPH, Rochester, NY<br />

2:20 PM Mechanisms from Studies <strong>of</strong> Human Obesity<br />

Sadaf Farooqi, PhD, Cambridge, United Kingdom<br />

2:40 PM Evaluation and Treatment <strong>of</strong> <strong>Hypertension</strong> in<br />

Childhood<br />

Joseph T. Flynn, MD, F<strong>ASH</strong>, Seattle, WA<br />

58


Sunday Afternoon MAY 22<br />

Sessions<br />

3:30 PM – 5:15 PM • Mercury Ballroom • Third Floor<br />

1 Aldosterone<br />

Co-Chairs: J. Howard Pratt, MD, Indianapolis, IN and<br />

Gordon H. Williams, MD, Boston, MA<br />

3:30 PM Non-Renal Effects <strong>of</strong> Aldosterone<br />

James M. Luther, MD, Nashville, TN<br />

3:50 PM Interactions Between Aldosterone and<br />

Nitric Oxide<br />

Charles J. Lowenstein, MD, Rochester, NY<br />

4:10 PM Role <strong>of</strong> Aldosterone and Mineralocorticoid Receptor<br />

Activation in Obesity Related <strong>Hypertension</strong><br />

John E. Hall, PhD, Jackson, MS<br />

Original Communications<br />

4:30 PM OR-6: Spironolactone Reverses Chlorthalidone-<br />

Induced Sympathetic Activation in Hypertensive<br />

Patients<br />

Prafull Raheja, Debbie Arbique, Zhijun Wang, Wanpen<br />

Vongpatanasin. UT Southwestern Medical Center,<br />

Dallas, TX, US.<br />

4:45 PM OR-7: Plasma Aldosterone Levels Affect Calcium<br />

Metabolism in Patients with Essential <strong>Hypertension</strong><br />

Gian Luca Colussi, Cristiana Catena, GianLuca Colussi,<br />

Leonardo A. Sechi. University <strong>of</strong> Udine, Udine, IT.<br />

5:00 PM OR-8: Inappropriately Intense Salt Restriction,<br />

Which Causes Elevation <strong>of</strong> Plasma Aldosterone<br />

Level, Might Augment Myocardial Fibrosis in<br />

Animal Model <strong>of</strong> Renal Tubular Injury<br />

Tatsuhiko Mori, 1 Kenichi Hasegawa, 2 Hirohisa<br />

Matsuda, 1 Yasuo Matsumura, 2 Nobukazu Ishizaka. 1<br />

1 Osaka Medical College, Takatsuki, JP; 2 Osaka<br />

University <strong>of</strong> Pharmaceutical Sciences, Takatsuki, JP.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

59


MAY 22<br />

Special Sessions<br />

Sunday Afternoon<br />

3:30 PM – 5:15 PM • East Ballroom • Third Floor<br />

2 <strong>Hypertension</strong> in Patients with Chronic Kidney<br />

Disease<br />

Co-Chairs: Rajiv Agarwal, MD, Indianapolis, IN and<br />

Aldo J. Peixoto, MD, F<strong>ASH</strong>, West Haven, CT<br />

3:30 PM Clinical Epidemiology <strong>of</strong> <strong>Hypertension</strong> and Chronic<br />

Kidney Disease<br />

Rajiv Agarwal, MD<br />

3:50 PM <strong>Hypertension</strong> in Advanced Kidney Disease<br />

Luis M. Ruilope, MD, Madrid, Spain<br />

4:10 PM <strong>Hypertension</strong> in Renal Transplant Patients<br />

Martin S. Zand, MD, Rochester, NY<br />

Original Communications<br />

4:30 PM OR-9: Administration-Time-Dependent Effects <strong>of</strong><br />

Angiotensin Receptor Blockers in Hypertensive<br />

Patients with Chronic Kidney Disease<br />

Ramon C. Hermida, Diana E. Ayala, Artemio Mojon,<br />

Maria J. Fontao, Luisa Chayan, Jose R. Fernandez.<br />

University <strong>of</strong> Vigo, Vigo, ES.<br />

4:45 PM OR-10: Carvedilol for the Treatment <strong>of</strong> Intradialytic<br />

<strong>Hypertension</strong>: The Mechanisms and Treatment <strong>of</strong><br />

Intradialytic <strong>Hypertension</strong> (MATCH) Study<br />

Jula K. Inrig, Peter Van Buren, Catherine Kim, Robert<br />

Toto. UT Southwestern, Dallas, TX, US.<br />

5:00 PM OR-11: Cardiovascular Risk Assessment – Addition<br />

<strong>of</strong> CKD and Race to the Framingham Equation<br />

Paul E. Drawz, 1,2 Sarah Baraniuk, 3 Barry R. Davis, 3<br />

Mahboob Rahman. 2,4 1 MetroHealth Medical Center,<br />

Cleveland, OH, US; 2 Case Western Reserve University,<br />

Cleveland, OH, US; 3 University <strong>of</strong> Texas School <strong>of</strong><br />

Public Health, Houston, TX, US; 4 University Hospitals<br />

Case Medical Center, Cleveland, OH, US.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

60


Sunday Afternoon MAY 22<br />

Sessions<br />

3:30 PM – 5:15 PM • West Ballroom • Third Floor<br />

3 Comprehensive Multi-Level Interventions for<br />

<strong>Hypertension</strong> Management in High-Risk Groups<br />

Co-Chairs: Daniel Levy, MD, Framingham, MA and<br />

Robert A. Phillips, MD, PhD, F<strong>ASH</strong>, Worcester, MA<br />

3:30 PM <strong>Hypertension</strong> in Minorities: A New York State<br />

Clinical Guidance Statement<br />

Joseph L. Izzo, Jr., MD, F<strong>ASH</strong>, Buffalo, NY<br />

3:50 PM Clinical Trial Interventions: Where Have We Gone<br />

Right or Wrong<br />

Bryan Williams, MD, Leicester, United Kingdom<br />

4:10 PM Integrated and Alternate Approaches to Treatment<br />

William J. Elliott, MD, PhD, F<strong>ASH</strong>, Yakima, WA<br />

Original Communications<br />

4:30 PM OR-12: Influence <strong>of</strong> Inflammatory and<br />

Prothrombotic Factors in Left Ventricular Structure<br />

and Function in Essential Hypertensive Patients<br />

Gregory Vyssoulis, 1 Eva Karpanou, 2 Stella Maria<br />

Kyvelou, 1 I. Barbetseas, 1 C. Stefanadis. 1 1 1st Cardiology<br />

Clinic Athens University Hippokration Hospital, GR;<br />

2 1st Cardiology Clinic Onassis Cardiosurgery Center,<br />

GR.<br />

4:45 PM OR-13: The Kaiser Permanente Northern California<br />

<strong>Hypertension</strong> Project 2001-2009: How an Integrated<br />

Care Delivery System Increased Blood Pressure<br />

Control Rates from 44% to 80% in 8 Years<br />

Marc G. Jaffe, Joseph D. Young. The Permanente<br />

Medical Group, Oakland, CA, US.<br />

5:00 PM OR-14: Intensive Blood Pressure Control Does Not<br />

Increase Falls and Fractures in Patients with Type 2<br />

Diabetes:The ACCORD Trial<br />

Karen Margolis, 1 Lisa Palermo, 2 Eric Vittingh<strong>of</strong>f, 2 Hal<br />

Atkinson, 3 Gregory Evans, 3 Bruce Hamilton, 4 Robert<br />

Josse, 5 Patrick O’Connor, 1 Debra Simmons, 6 Margaret<br />

Tiktin, 7 Ann Schwartz. 2 1 HealthPartners Research<br />

Foundation, US; 2 U <strong>of</strong> CA-SF, US; 3 Wake Forest SOM,<br />

US; 4 Baltimore VAMC, US; 5 University <strong>of</strong> Toronto,<br />

CA; 6 Central Arkansas Veterans Healthcare System,<br />

US; 7 Case Western Research University, US.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

61


MAY 22<br />

Sessions<br />

Sunday Afternoon<br />

3:30 PM – 5:15 PM • Trianon Rendezvous • Third Floor<br />

New Perspectives in ISHIB Consensus Statement:<br />

Is Clinical Judgment Medically Appropriate<br />

Held in Partnership with the International <strong>Society</strong> on <strong>Hypertension</strong><br />

in Blacks (ISHIB)<br />

Co-Chairs: Kenneth A. Jamerson, MD, F<strong>ASH</strong>, Ann Arbor, MI and<br />

Daniel T. Lackland, DrPH, F<strong>ASH</strong>, Charleston, SC<br />

3:30 PM Is There a Role for Opinion in Guidelines or<br />

Consensus Reports A Perspective<br />

Keith C. Ferdinand, MD, F<strong>ASH</strong>, Atlanta, GA<br />

3:45 PM Highlights <strong>of</strong> the New Consensus Statement<br />

Shawna D. Nesbitt, MD, MS, F<strong>ASH</strong>, Dallas, TX<br />

Debate<br />

4:00 PM Supporting Perspective<br />

John M. Flack MD, MPH, Detroit, MI<br />

4:20 PM Opposing Perspective<br />

William C. Cushman, MD, F<strong>ASH</strong>, Memphis, TN<br />

4:40 PM Rebuttal<br />

62


Sunday Afternoon MAY 22<br />

Sessions<br />

3:30 PM – 5:00 PM • Trianon Ballroom • Third Floor<br />

Control <strong>of</strong> <strong>Hypertension</strong> is Leaving the Office:<br />

The Role <strong>of</strong> Home Blood Pressure and Telemedicine<br />

Co-Chairs: Lawrence R. Krak<strong>of</strong>f, MD, New York, NY and<br />

William B. White, MD, F<strong>ASH</strong>, Farmington, CT<br />

3:30 PM Home Blood Pressure and Cardiovascular Risk<br />

Gianfranco Parati, MD, Milan, Italy<br />

3:52 PM Using Home Blood Pressure in Clinical Practice<br />

Gbenga Ogedegbe, MD, MPH, MS, F<strong>ASH</strong>, New York,<br />

NY<br />

4:14 PM Home Blood Pressure and Telemetry to Improve<br />

<strong>Hypertension</strong> Control<br />

Richard J. McManus, MD, Birmingham, United<br />

Kingdom<br />

4:36 PM The Future <strong>of</strong> Telemedicine in the Management <strong>of</strong><br />

<strong>Hypertension</strong><br />

Lawrence R. Krak<strong>of</strong>f, MD<br />

Supported by an educational grant from Omron Healthcare, Inc.<br />

63


MAY 23<br />

Satellite Symposium<br />

6:00 AM – 7:30 AM • Trianon Ballroom • Third Floor<br />

Monday morning<br />

The Role <strong>of</strong> Beta-Blockers in <strong>Hypertension</strong>:<br />

A Healthy Debate<br />

Chairman: Jan N. Basile, MD, F<strong>ASH</strong>, Charleston, SC<br />

Learning Objectives:<br />

• Describe the differences and similarities<br />

among agents within the beta-blocker class <strong>of</strong><br />

antihypertensive agents<br />

• Summarize the results <strong>of</strong> key clinical trials<br />

investigating beta blockade in African <strong>American</strong>,<br />

Hispanic, and Asian patient populations<br />

• List reasons why beta-blockers should or should<br />

not be used as first line or second step therapy for<br />

hypertension<br />

<strong>Program</strong> Agenda:<br />

6:00 AM Welcome<br />

Overview <strong>of</strong> <strong>Program</strong> Learning Objectives<br />

Audience Response System (ARS)<br />

Jan N. Basile, MD, F<strong>ASH</strong>, Chairman<br />

6:05 AM The Class Effect With Beta-Blockers: Does One Size<br />

Fit All<br />

Addison A. Taylor, MD, PhD, F<strong>ASH</strong>,<br />

Houston, TX<br />

6:25 AM Beta-Blockers and Ethnicity: What Do We Really<br />

Know<br />

Henry A. Punzi, MD, Dallas, TX<br />

6:45 AM Debate: Beta-Blockers Are Appropriate for First<br />

Line or Second Step Therapy in Patients With<br />

<strong>Hypertension</strong><br />

AGREE: William H. Frishman, MD,<br />

Valhalla, NY<br />

DISAGREE: Franz H. Messerli, MD, F<strong>ASH</strong>,<br />

New York, NY<br />

7:15 AM Faculty Panel Discussion With Questions From the<br />

Audience<br />

Jan N. Basile, MD, F<strong>ASH</strong>, Moderator<br />

7:30 AM Review <strong>of</strong> <strong>Program</strong> Learning Objectives and Closing<br />

Remarks<br />

Jan N. Basile, MD, F<strong>ASH</strong>, Moderator<br />

A Breakfast will be held at 5:30 AM in the<br />

Trianon Ballroom.<br />

Supported by an educational grant from Forest Laboratories, Inc.<br />

64


Monday Morning MAY 23<br />

Sessions<br />

8:00 AM – 10:05 AM • Mercury Ballroom • Third Floor<br />

1 Off-Target Cardiovascular Effects <strong>of</strong> Non-<br />

Cardiovascular Drugs<br />

Co-Chairs: Franz H. Messerli, MD, F<strong>ASH</strong>, New York, NY and<br />

Suzanne Oparil, MD, F<strong>ASH</strong>, Birmingham, AL<br />

8:00 AM Anti-VEGF and Other Chemotherapeutic Agents<br />

Rhian M. Touyz, MD, PhD, Ottawa, Canada<br />

8:20 AM Non-Steroidal Anti-Inflammatory Drugs<br />

Raymond C. Harris, MD, Nashville, TN<br />

8:40 AM PDE5 Inhibitors and Organic Nitrates<br />

David J. Webb, MD, Edinburgh, United Kingdom<br />

9:00 AM PPAR Agents<br />

Julio A. Panza, MD, Washington, DC<br />

Original Communications<br />

9:20 AM OR-15: Effects on Ambulatory Blood Pressure <strong>of</strong><br />

Adding Low-Dose Aspirin at Bedtime in Subjects<br />

with Treated <strong>Hypertension</strong><br />

Ramon C. Hermida, University <strong>of</strong> Vigo, Vigo, ES.<br />

9:35 AM OR-16: Cardio-Metabolic Effects <strong>of</strong> Acute and<br />

Sub-Acute Exposures to Ambient Levels <strong>of</strong> Fine<br />

Particulate Matter Air Pollution<br />

Robert D. Brook, 1 Robert L. Bard, 1 J. Timothy<br />

Dvonch, 1 Masako Morishita, 1 Niko Kaciroti, 1 Sanjay<br />

Rajagopalan. 2 1 University <strong>of</strong> Michigan, US; 2 Ohio State<br />

University, US.<br />

9:50 AM OR-17: Impact <strong>of</strong> Nonsteroidal Anti-Inflammatory<br />

Drugs on Nocturnal Blood Pressure<br />

W. B. White†, 1 L. Lavange, 2 A. Marquis. 2 1 University <strong>of</strong><br />

Connecticut School <strong>of</strong> Medicine, Farmington, CT, US;<br />

2 University <strong>of</strong> North Carolina at Chapel Hill, Chapel<br />

Hill, NC, US.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

65


MAY 23<br />

Sessions<br />

Monday morning<br />

8:00 AM – 10:00 AM • East Ballroom • Third Floor<br />

2 New Insights into the Role <strong>of</strong> Uric Acid in<br />

<strong>Hypertension</strong><br />

Co-Chairs: Richard J. Johnson, MD, Denver, CO and<br />

Andrew Whelton, MD, Baltimore, MD<br />

8:00 AM Fructose-Obesity-Uric Acid Link<br />

Richard J. Johnson, MD<br />

8:25 AM Oxidative Stress and Impact <strong>of</strong> Uric Acid<br />

Allan D. Struthers, MD, Dundee, United Kingdom<br />

8:40 AM Urate-Lowering and Blood Pressure Response<br />

Daniel I. Feig, MD, PhD, Houston, TX<br />

Original Communications<br />

9:00 AM OR-18: Associations <strong>of</strong> Uric Acid with Asymmetric<br />

Dimethylarginine, L-arginine and Arterial Stiffening<br />

in <strong>Hypertension</strong><br />

K. Dimitriadis, C. Tsioufis, A. Aggelis, S. Kyvelou,<br />

E. Stefanadi, L. Lioni, D. Flessas, C. Stefanadis.<br />

Hippokration Hospital, Athens, GR.<br />

9:15 AM OR-19: Epoxyeicosatrienoic Acid Agonist Attenuates<br />

Adipogenesis Derived from Mesenchymal Stem Cells<br />

Via Heme Oxygenase-PPARg Pathways<br />

DongHyun Kim, 1 Luca Vanella, 1 Nitin Puri, 1 Michal L.<br />

Schwartzman, 2 John R. Falck, 3 Komal Sodhi, 1 Nader G.<br />

Abraham. 1 1 University <strong>of</strong> Toledo College <strong>of</strong> Medicine,<br />

Toledo, OH, US; 2 New York Medical College, Valhalla,<br />

NY, US; 3 University <strong>of</strong> Texas Southwestern Medical<br />

Center, Dallas, TX, US.<br />

9:30 AM OR-20: Effect <strong>of</strong> Allopurinol on Blood Pressure:<br />

A Systematic Review<br />

Vikram Agarwal, 1 Nidhi Hans, 2 Franz Messerli. 1 1 St.<br />

Luke’s-Roosevelt Hospital Center, NY, US; 2 Harvard<br />

School <strong>of</strong> Public Health, MA, US.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

66


Monday Morning MAY 23<br />

Sessions<br />

8:00 AM – 10:00 AM • West Ballroom • Third Floor<br />

3 Devices and Surgical Ablation for Refractory<br />

<strong>Hypertension</strong><br />

Co-Chairs: Domenic A. Sica, MD, Richmond, VA and<br />

Ronald G. Victor, MD, Los Angeles, CA<br />

8:00 AM How to Evaluate and Choose the Appropriate<br />

Patient<br />

Henry Krum, MBBS, PhD, Melbourne, Australia<br />

8:20 AM Renal Nerve Ablation<br />

Roland E. Schmieder, MD, Erlangen, Germany<br />

8:40 AM Carotid Baroreceptor Manipulation<br />

John D. Bisognano, MD, PhD, F<strong>ASH</strong>, Rochester, NY<br />

Original Communications<br />

9:00 AM OR-21: True Resistant <strong>Hypertension</strong>: Optimal Cut-<br />

Off Ambulatory Blood Pressure Level for Diagnosis<br />

and Effect <strong>of</strong> Spironolactone<br />

Jose A. Garcia‐Donaire, Julian Segura, Cesar Cerezo,<br />

Luis M. Ruilope. Hospital 12 de Octubre, Madrid, ES.<br />

9:15 AM OR-22: Individualized <strong>Program</strong>ming Demonstrates<br />

Feasibility <strong>of</strong> Unilateral Approach to Delivery <strong>of</strong><br />

Baroreflex Activation Therapy®<br />

Domenic Sica†, 1 John Bisognano, 2 Mitra Nadim, 3 Luis<br />

Sanchez, 4 George Bakris. 5 1 Virginia Commonwealth<br />

University, Richmond, VA, US; 2 University <strong>of</strong><br />

Rochester, Rochester, NY, US; 3 University <strong>of</strong> Southern<br />

California, Los Angeles, CA, US; 4 Washington<br />

University, St. Louis, MO, US; 5 University <strong>of</strong> Chicago,<br />

Chicago, IL, US.<br />

9:30 AM OR-23: The Efficacy <strong>of</strong> Adding the Direct Renin<br />

Inhibitor Aliskiren on the Patients with Resistant<br />

<strong>Hypertension</strong> (55% Had Chronic Kidney Disease)<br />

– Subgroup Analysis on Different Levels <strong>of</strong> Plasma<br />

Renin Activity<br />

Fumitoshi Satoh, Ryo Morimoto, Masataka Kudo,<br />

Yoshitugu Iwakura, Yoshikiyo Ono, Sadayoshi Ito.<br />

Tohoku University Hospital, Sendai, JP<br />

9:45 AM OR-24: Exploring the Prevalence <strong>of</strong> Resistant<br />

<strong>Hypertension</strong> in a Large Ethnically Diverse<br />

Hypertensive Population<br />

Simran Bhandari, In Lu Liu, Jiaxiao Shi, Federico<br />

Calara, Scott Rasgon, John Sim. Kaiser Permanente<br />

Los Angeles Medical Center, Los Angeles, CA, US.<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

67


MAY 23<br />

Sessions<br />

Monday morning<br />

8:30 AM – 10:00 AM • Trianon Rendezvous • Third Floor<br />

The Kidney Early Evaluation <strong>Program</strong> (KEEP):<br />

A New Longitudinal Dimension for a New Decade<br />

Held in Partnership with the National Kidney Foundation (NKF)<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

Joseph A. Vassalotti, MD, New York, NY<br />

8:30 AM KEEP: CKD Screening <strong>Program</strong> Overview<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

8:52 AM KEEP: Longitudinal Preliminary Results<br />

Joseph A. Vassalotti, MD<br />

9:14 AM KEEP: Experience with the CKD-EPI Equation<br />

Lesley A. Stevens, MD, MS Boston, MA<br />

9:36 AM Where Do We Stand on Blood Pressure Control<br />

in KEEP<br />

Adam Whaley‐Connell, DO, F<strong>ASH</strong>, Columbia, MO<br />

68


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

Posters will be displayed in the Second Floor Promenade.<br />

Monday, May 23, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 5:30 PM • Poster Viewing: 4:30 PM – 5:30 PM<br />

Featured Posters<br />

Cardiac Structure and Function.................................... (FP-9 – FP-13)<br />

Arterial Structure and Compliance...........................(PO-245 – PO-259)<br />

Blood Pressure Measurement/Monitoring............(PO-260 – PO-305A)<br />

Cellular Mechanisms (Cell Biology;<br />

Cell Membrane Transport/Ion Channels;<br />

Coagulation/Thrombosis; Growth Factors).............(PO-306 – PO-308)<br />

Lipid Metabolism...........................................................................(PO-309)<br />

Neural Hormonal Mechanisms (Renin; Neural Control; Vasoactive<br />

Autacoids).....................................................................(PO-310 – PO-312)<br />

Non – Pharmacological Therapy (Alternative<br />

Medicine; Diet; Physical Activity).............................(PO-313 – PO-322)<br />

Nutrition and Cardiovascular Prevention................(PO-323 – PO-330)<br />

Obesity...........................................................................(PO-331 – PO-339)<br />

Patient – Provider-Healthcare System Issues...........(PO-340 – PO-355)<br />

Preclinical Models/Experimental <strong>Hypertension</strong>.....(PO-357 – PO-358)<br />

Pregnancy......................................................................(PO-359 – PO-361)<br />

Salt-Sensitive Mechanisms <strong>of</strong> <strong>Hypertension</strong>............(PO-362 – PO-364)<br />

Secondary <strong>Hypertension</strong>.............................................(PO-365 – PO-367)<br />

Late-Breaking Posters.........................................(LB-PO-01 – LB-PO-03)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

69


MAY 23<br />

Sessions<br />

Monday morning<br />

10:05 AM – 11:35 AM • Trianon Ballroom • Third Floor<br />

Hyperkalemia Management in High Risk Patients:<br />

New Evidence-Based Approaches<br />

Co-Chairs: Murray Epstein, MD, Miami, FL and<br />

Luis M. Ruilope, MD, Madrid, Spain<br />

10:05 AM The Spectrum <strong>of</strong> Cardiovascular Risk Associated<br />

with Potassium Abnormalities<br />

Domenic A. Sica, MD, Richmond, VA<br />

10:35 AM Use <strong>of</strong> RAAS Inhibitors for Cardio-Renal Risk<br />

Reduction and Potassium Management<br />

Luis M. Ruilope, MD<br />

11:05 AM Conventional versus Novel Approaches to the<br />

Management <strong>of</strong> Hyperkalemia<br />

David A. Bushinsky, MD, Rochester, NY<br />

Supported by an educational grant from Relypsa, Inc.<br />

70


Monday Morning MAY 23<br />

Debate<br />

11:45 AM – 12:15 PM • Trianon Ballroom • Third Floor<br />

Debate: Are Elevated Potassium Levels Really a<br />

Concern<br />

Moderator: Barry J. Materson, MD, MBA, F<strong>ASH</strong>, Miami, FL<br />

11:35 AM Yes: Vasilios Papademetriou, MD, F<strong>ASH</strong>,<br />

Washington, DC<br />

11:45 AM No: Bertram Pitt, MD, Ann Arbor, MI<br />

11:55 AM Rebuttal<br />

71


MAY 23<br />

Sessions<br />

Monday morning<br />

10:30 AM – 12:00 PM • Mercury Ballroom • Third Floor<br />

1 Immune Mechanisms in <strong>Hypertension</strong><br />

Co-Chairs: Michael W. Brands, PhD, Augusta, GA and<br />

David G. Harrison, MD, Atlanta, GA<br />

10:30 AM The Role <strong>of</strong> Inflammatory Cytokines in Pregnancy-<br />

Induced <strong>Hypertension</strong><br />

Babbette LaMarca, PhD, Jackson, MS<br />

10:52 AM T-Regulatory Cells in <strong>Hypertension</strong><br />

Ernesto L. Schiffrin, MD, PhD, Montreal, Canada<br />

11:14 AM Novel Mechanisms <strong>of</strong> Renal Injury in <strong>Hypertension</strong><br />

David L. Mattson, PhD, Milwaukee, WI<br />

11:36 AM Adaptive Immune Response in <strong>Hypertension</strong><br />

David G. Harrison, MD<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

72


Monday Morning MAY 23<br />

Sessions<br />

10:30 AM – 12:00 PM • East Ballroom • Third Floor<br />

2 Management <strong>of</strong> Elevated Blood Pressure in the<br />

Hospital Setting<br />

Co-Chairs: William J. Elliott, MD, PhD, F<strong>ASH</strong>, Yakima, WA and<br />

Sandra J. Taler, MD, F<strong>ASH</strong>, Rochester, MN<br />

10:30 AM <strong>Hypertension</strong> in the Emergency Department<br />

C. Venkata S. Ram, MD, F<strong>ASH</strong>, Dallas, TX<br />

10:52 AM <strong>Hypertension</strong> in the Inpatient Unit<br />

Alan B. Weder, MD, Ann Arbor, MI<br />

11:14 AM <strong>Hypertension</strong> in the Peri-operative Period<br />

Daniel Duprez, MD, PhD, F<strong>ASH</strong>, Minneapolis, MN<br />

11:36 AM <strong>Hypertension</strong> in the Dialysis Unit<br />

Aldo J. Peixoto, MD, F<strong>ASH</strong>, West Haven, CT<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

73


MAY 23<br />

Sessions<br />

Monday morning<br />

10:30 AM – 12:00 PM • West Ballroom • Third Floor<br />

3 Management <strong>of</strong> <strong>Hypertension</strong> in Diabetics and<br />

Chronic Kidney Disease<br />

Co-Chairs: James R. Sowers, MD, F<strong>ASH</strong>, Columbia, MO and<br />

Bryan Williams, MD, Leicester, United Kingdom<br />

10:30 AM Is There an Optimal Blood Pressure Goal in the<br />

Patient with Type-2 Diabetes<br />

Matthew R. Weir, MD, F<strong>ASH</strong>, Baltimore, MD<br />

10:52 AM Prevention <strong>of</strong> Renal Disease in the Hypertensive,<br />

Type-2 Diabetic<br />

Robert D. Toto, MD, Dallas, TX<br />

11:14 AM Prevention <strong>of</strong> Renal Disease in the African-<br />

<strong>American</strong> Patient with <strong>Hypertension</strong><br />

Velvie A. Pogue, MD, New York, NY<br />

11:36 AM Management <strong>of</strong> Metabolic Co-Morbidities in the<br />

Hypertensive Patient<br />

Mark E. Molitch, MD, Chicago, IL<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

74


Monday Morning MAY 23<br />

Sessions<br />

10:30 AM – 12:00 PM • Trianon Rendezvous • Third Floor<br />

Blood Pressure Variability and Treatment Goals<br />

Held in Partnership with the European <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong><br />

(ESH)<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

Krzyszt<strong>of</strong> Narkiewicz, MD, PhD, Gdánsk, Poland<br />

10:30 AM Short and Long-Term Blood Pressure Variability<br />

Giuseppe Mancia, MD, Milan, Italy<br />

10:52 AM J-Curve Revisited<br />

Athanasios J. Manolis, MD, PhD, Athens, Greece<br />

11:14 AM Target Blood Pressure in Nephropatic Patients<br />

George L. Bakris, MD, F<strong>ASH</strong><br />

11:36 AM Ambulatory and Home Blood Pressure Targets<br />

William B. White, MD, F<strong>ASH</strong>, Farmington, CT<br />

75


MAY 23<br />

Plenary Session II<br />

Monday Afternoon<br />

1:30 PM – 4:00 PM • East Ballroom • Third Floor<br />

Award Presentations<br />

Co-Chairs:<br />

George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

Norman K. Hollenberg, MD, PhD, Boston, MA<br />

1:30 PM Robert Tigerstedt Award Lecture<br />

Acetyl-Ser-Asp-Lys-Pro, an Endogenous<br />

Tetrapeptide: Role in Target Organ Damage in<br />

<strong>Hypertension</strong>, and Autoimmune Myocarditis<br />

Oscar A. Carretero, MD, F<strong>ASH</strong>, Detroit, MI<br />

2:00 PM Young Scholar Award Lecture*<br />

Novel Mechanisms Linking Chronic Inflammation<br />

and <strong>Hypertension</strong> in Systemic Lupus Erythematosus<br />

Michael J. Ryan, PhD, Jackson, MS<br />

2:20 PM Young Scholar Award Lecture*<br />

State Rescued with Innovative BNP Based<br />

Technologies<br />

Alessandro Cataliotti, MD, PhD, Rochester, MN<br />

2:40 PM Marvin Moser Clinical Award Lecture<br />

Water Immersion: A Model <strong>of</strong> Volume Expansion<br />

for Assessing Renin-Aldosterone Responsiveness<br />

and Renal Sodium Handling in Humans<br />

Murray Epstein, MD, Miami, FL<br />

State-<strong>of</strong>-the-Art Lectures<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

David G. Harrison, MD, Atlanta, GA<br />

3:00 PM Leukocyte Telomere Length Genetics and<br />

Cardiovascular Disease<br />

Abraham Aviv, MD, Newark, NJ<br />

3:30 PM Development <strong>of</strong> Cardiac Hypertrophy<br />

Joseph A. Hill, MD, PhD, Dallas, TX<br />

*Supported by an educational grant from SERVIER.<br />

76


Monday Afternoon MAY 23<br />

Debates<br />

4:30 PM – 5:00 PM<br />

Beekman Parlor • Second Floor<br />

Debate: The Dominant Contributor to Systemic<br />

<strong>Hypertension</strong> is<br />

Moderator: Murray Epstein, MD, Miami, FL<br />

4:30 PM Sympathetic Nervous System not the RAAS<br />

Murray D. Esler, MBBS, PhD, Melbourne, Australia<br />

4:40 PM Activation <strong>of</strong> the Intrarenal RAAS not the SNS<br />

L. Gabriel Navar, PhD, New Orleans, LA<br />

4:50 PM Rebuttal<br />

Sutton North • Second Floor<br />

Debate: <strong>Hypertension</strong> is a Disorder <strong>of</strong> the Kidney<br />

Moderator: Jens Titze, MD, Erlangen, Germany<br />

4:30 PM Yes: Joey P. Granger, PhD, Jackson, MS<br />

4:40 PM No: Allyn L. Mark, MD, Iowa City, IA<br />

4:50 PM Rebuttal<br />

77


MAY 24<br />

Sessions<br />

Tuesday Morning<br />

8:15 AM – 9:30 AM • West Ballroom • Third Floor<br />

Late-Breaking Clinical Trials<br />

Co-Chairs: George L. Bakris, MD, F<strong>ASH</strong>, Chicago, IL and<br />

William B. White, MD, F<strong>ASH</strong>, Farmington, CT<br />

8:15 AM LB-OR-01: Evaluation <strong>of</strong> Cardiovascular Effects in<br />

Three Double-Blind, Placebo-Controlled Clinical<br />

Trials with Controlled-Release Phentermine/<br />

Topiramate<br />

Suzanne Oparil†, 1 Wesley Day, 2 Charles Bowden. 2<br />

1 University <strong>of</strong> Alabama, Birmingham, AL, US; 2 Vivus,<br />

Mountain View, CA, US.<br />

8:30 AM LB-OR-02: Longterm (3 – 5 Months) Spaceflight<br />

Promotes a Sustained Decrease in Blood Pressure<br />

and Systemic Vascular Resistance in Astronauts<br />

Peter Norsk, 1 Ali Asmar, 1 Niels Juel Christensen. 2<br />

1 University <strong>of</strong> Copenhagen, Copenhagen, DK; 2 Herlev<br />

University Hospital, Herlev, DK.<br />

8:45 AM LB-OR-03: Azilsartan Medoxomil Plus<br />

Chlorthalidone Reduces BP More Effectively<br />

Than Olmesartan Plus HCTZ in Stage 2 Systolic<br />

<strong>Hypertension</strong><br />

William C. Cushman†, 1 George Bakris, 2 William B.<br />

White, 3 Michael Weber, 4 Domenic Sica, 5 Andrew<br />

Roberts, 6 Eric Lloyd, 6 Stuart Kupfer. 6 1 University <strong>of</strong><br />

TN College <strong>of</strong> Medicine, US; 2 U <strong>of</strong> Chicago Pritzker<br />

School <strong>of</strong> Medicine, US; 3 U <strong>of</strong> CT School <strong>of</strong> Medicine,<br />

US; 4 New York, NY, US; 5 VA Commonwealth U Health<br />

System, US; 6 Takeda Global Research & Development,<br />

US.<br />

9:00 AM LB-OR-04: Common Blood Pressure Genetic<br />

Variants and Their Relations to <strong>Hypertension</strong>,<br />

Target-Organ Damage, and Cardiovascular Disease<br />

Risk: The International Collaboration for Blood<br />

Pressure Genome-Wide Association Studies (ICBP)<br />

Georg Ehret, 1 Patricia Munroe, 4 Christopher Newton-<br />

Cheh, 5 Kenneth Rice, 3 Cornelia van Duin, 6 Aravinda<br />

Chakravarti, 1 Daniel Levy, 2 Mark Caulfield, 4 Toby<br />

Johnson. 4 1 Johns Hopkins, Baltimore, MD, US;<br />

2 NHLBI, Framingham, MA, US; 3 University <strong>of</strong><br />

Washington, Seattle, WA, US; 4 London School <strong>of</strong><br />

Medicine, London, GB; 5 Broad Institute, Cambridge,<br />

MA, US; 6 The Rotterdam Study, Rotterdam, NL.<br />

continued…<br />

78


Tuesday Morning MAY 24<br />

Sessions continued<br />

9:15 AM LB-OR-05: Sixteen Novel Loci Influence Blood<br />

Pressure in Diverse Populations<br />

Georg B. Ehret, 1 Patricia B. Munroe, 2 Kenneth M.<br />

Rice, 3 Murielle Bochud, 4 Andrew D. Johnson, 5<br />

Daniel I. Chasman, 6 Albert V. Smith, 7 Bruce M.<br />

Pstay, 3 Goncalo R. Abecasis, 8 Aravinda Chakravarti, 1<br />

Paul Elliott, 9 Cornelia M. van Duijn, 10 Christopher<br />

Newton Cheh, 11 Daniel Levy, 5 Mark J. Caulfield, 2<br />

Toby Johnson. 2 1 Johns Hopkins University School <strong>of</strong><br />

Medicine, US; 2 Queen Mary University <strong>of</strong> London,<br />

GB; 3 University <strong>of</strong> Washington, Seattle, US; 4 University<br />

<strong>of</strong> Lausanne, CH; 5 National Heart Lung, and Blood<br />

Institute, Bethesda, US; 6 Brigham and Women’s<br />

Hospital, Boston, US; 7 University <strong>of</strong> Iceland, Reykajvik,<br />

IS; 8 University <strong>of</strong> Michigan School <strong>of</strong> Public Health,<br />

Ann Arbor, US; 9 Imperial College, GB; 10 Erasmus<br />

Medical Center, NL; 11 Massachusetts General Hospital,<br />

US.<br />

79


MAY 24<br />

Sessions<br />

Tuesday Morning<br />

10:00 AM – 11:30 AM • Sutton North • Second Floor<br />

1 Salt-Sensitive Mechanisms <strong>of</strong> <strong>Hypertension</strong><br />

Co-Chairs: Allyn L. Mark, MD, Iowa City, IA and<br />

Jens Titze, MD, Erlangen, Germany<br />

10:00 AM Renal Sodium Handling, Endothelin, and<br />

Genetic Models<br />

Donald E. Kohan, MD, PhD, Salt Lake City, UT<br />

10:30 AM Significance <strong>of</strong> Non-Osmotic Sodium<br />

Jens Titze, MD<br />

11:00 AM Nitric Oxide, Superoxide and Renal Sodium<br />

Handling<br />

Jeffrey L. Garvin, PhD, Detroit, MI<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

80


Tuesday Morning MAY 24<br />

Sessions<br />

10:00 AM – 11:30 AM • Sutton Center • Second Floor<br />

2 Integrated Cardiovascular Disease Guidelines<br />

and Implementation<br />

Co-Chairs: Henry R. Black, MD, F<strong>ASH</strong>, New York, NY and<br />

Sidney Smith, Jr., MD, Chapel Hill, NC<br />

10:00 AM Rationale for the NHLBI Integrated Cardiovascular<br />

Risk Reduction Guidelines<br />

Sidney Smith, Jr., MD<br />

10:30 AM Implementation <strong>of</strong> the Integrated Cardiovascular<br />

Risk Reduction Guidelines<br />

John Merenich, MD, Denver, CO<br />

11:00 AM Results <strong>of</strong> the Integrated Cardiovascular Risk<br />

Reduction Guidelines Implementation in Northern<br />

California<br />

Alan S. Go, MD, Oakland, CA<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

81


MAY 24<br />

Sessions<br />

Tuesday Morning<br />

10:00 AM – 11:30 AM • Beekman Parlor • Second Floor<br />

3 Nutrition and Cardiovascular Prevention<br />

Co-Chairs: Lawrence J. Appel, MD, MPH, F<strong>ASH</strong>, Baltimore, MD<br />

and David S. Kountz, MD, Neptune, NJ<br />

10:00 AM High Fructose Corn Syrup, Sucrose and Fructose:<br />

What Do We Really Know<br />

James Rippe, MD, Shrewsbury, MA<br />

10:30 AM Cations and Blood Pressure Control<br />

Lawrence J. Appel, MD, MPH, F<strong>ASH</strong><br />

11:00 AM Low Protein and Renal Protection<br />

Robert D. Toto, MD, Dallas, TX<br />

1 Pathobiology Track 2 Translational Track 3 Therapy Track<br />

82


<strong>Hypertension</strong> Awareness Campaign for Your Patients<br />

ARE YOU 1 IN 3<br />

GET THE FACTS. KNOW YOUR RISKS.<br />

Help spread the word by visiting 1in3people.com.<br />

As per the <strong>American</strong> Heart Association, 1 in 3 US adults has high blood pressure. 1<br />

1. Roger VL, Go AS, Lloyd-Jones DM, et al; for the <strong>American</strong> Heart Association Statistics Committee and Stroke<br />

Statistics Subcommittee. Heart disease and stroke statistics—<strong>2011</strong> update: a report from the <strong>American</strong><br />

Heart Association. Circulation. <strong>2011</strong>;123;e18-e209.<br />

Novartis Pharmaceuticals Corporation<br />

East Hanover, New Jersey 07936<br />

© <strong>2011</strong> Novartis Printed in USA 4/11 CVF-1058015 Printed on Recycled Paper


<strong>2011</strong><br />

<strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong><br />

<strong>Program</strong><br />

Posters


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

Posters will be displayed in the Second Floor Promenade.<br />

Saturday, May 21, <strong>2011</strong><br />

Posters on Display: 4:30 PM – 7:30 PM • Poster Viewing: 6:00 PM – 7:00 PM<br />

Adolescent <strong>Hypertension</strong> and Obesity.............................. (PO-1 – PO-5)<br />

Antiatherosclerotic Drugs................................................... (PO-6 – PO-7)<br />

Cardiac Structure and Function/Imaging....................... (PO-8 – PO-10)<br />

Comprehensive Multi-Level Interventions for<br />

<strong>Hypertension</strong> Management in High-Risk Groups......(PO-11 – PO-30)<br />

Endothelial Function.......................................................(PO-31 – PO-45)<br />

Epidemiology/Special Populations................................(PO-46 – PO-78)<br />

Immune Mechanisms in <strong>Hypertension</strong>........................(PO-79 – PO-82)<br />

Metabolic Syndrome (Diabetes/Glycemic Control;<br />

Dysglycemic Drugs; Insulin Resistance).....................(PO-83 – PO-102)<br />

New Insights into the Role <strong>of</strong> Uric Acid<br />

in <strong>Hypertension</strong>............................................................(PO-103 – PO-104)<br />

Pediatric <strong>Hypertension</strong>...............................................(PO-105 – PO-111)<br />

Risk Factors (Lipids)....................................................(PO-112 – PO-115)<br />

Stroke.............................................................................(PO-117 – PO-119)<br />

Vascular Injury/Inflammation and Remodeling......(PO-120 – PO-123)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

86


Saturday Afternoon MAY 21<br />

Posters<br />

4:30 PM – 7:30 PM • Second Floor Promenade<br />

Adolescent hypertension and obesity<br />

PO-1:<br />

PO-2:<br />

PO-3:<br />

PO-5:<br />

Common Carotid Artery Intima-Media Thickness<br />

in Patients with Abdominal Obesity and Essential<br />

<strong>Hypertension</strong><br />

Evgeny V. Shlyakhto, 1 Olga D. Belyaeva, 2 Olga O.<br />

Bolshakova, 1 Aelita V. Berezina, 2 Olga O. Berkovich, 2<br />

Elena I. Baranova. 2 1 Almazov Federal Heart, Blood<br />

and Endocrinology Centre, Saint-Petersburg, RU;<br />

2 Saint-Petersburg State Medical University, Saint-<br />

Petersburg, RU.<br />

Prevalence <strong>of</strong> <strong>Hypertension</strong> in Pediatric Oncology<br />

Survivors<br />

Kathy K. Y. Lee‐Son, 1 Sheila L. Pritchard, 2 Douglas<br />

G. Matsell, 1 Josephine X. Chow, 1 Janis M. Dionne. 1<br />

1 BC Children’s Hospital, Vancouver, BC, CA; 2 BC<br />

Children’s Hospital, Vancouver, BC, CA.<br />

Blood Pressure Variability in White Coat<br />

Hypertensive Adolescents<br />

Egle R. Silva, Jose J. Villasmil, Greily A. Bermudez,<br />

Mayela J. Bracho, Carlos E. Esis, Gustavo E. Calmon,<br />

Alicex C. Gonzalez. Instituto de Enfermedades<br />

Cardiovasculares, Universidad del Zulia, Maracaibo,<br />

VE.<br />

Pharmacologic Management <strong>of</strong> Primary<br />

<strong>Hypertension</strong> in Adolescents<br />

Esther Yoon, Lisa Cohn, Albert Rocchini, David<br />

Kershaw, Gary Freed, Frank Ascione, Sarah Clark.<br />

University <strong>of</strong> Michigan, US.<br />

Antiatherosclerotic Drugs<br />

PO-6:<br />

PO-7:<br />

Effects <strong>of</strong> 3-Hydroxy-3-Methylglutaryl Coenzyme A<br />

Reductase Inhibitors on Blood Pressure<br />

Vikram V. Agarwal, Alexandros Briasoulis, Franz H.<br />

Messerli. St. Luke’s-Roosevelt Hospital, Columbia<br />

University College <strong>of</strong> Physicians and Surgeons, New<br />

York, NY, US.<br />

Statin Effect on the Blood Pressure in Young and<br />

Elderly Adults: Meta-Analysis<br />

Camila Hartmann, Manuela S. Baldo, Talita R.<br />

Strano, Tariane F. Foiato, Emilton Lima, Jr.. Pontifícia<br />

Universidade Católica do Paraná, Curitiba, PR, BR.<br />

Cardiac Structure and Function/Imaging<br />

PO-8:<br />

Effect <strong>of</strong> Telmisartan on Paroxymal Atrial<br />

Fibrillation in Hypertensive Patients with Different<br />

Left Atrial Size<br />

Roberto Fogari, Amedeo Mugellini, Annalisa Zoppi,<br />

Gianluigi Marasi, Pierangelo Lazzari. University <strong>of</strong><br />

Pavia, Pavia, IT.<br />

87


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-9:<br />

PO-10:<br />

Effect <strong>of</strong> Aliskiren on QT Dispersion in Diabetic and<br />

Non Diabetic Hypertensive Patients<br />

Roberto Fogari, Amedeo Mugellini, Annalisa Zoppi,<br />

Gianluigi Marasi, Pierangelo Lazzari. University <strong>of</strong><br />

Pavia, IT.<br />

Impact <strong>of</strong> Antihypertensive Therapy on<br />

Dyssynchrony in Patients with Never-Treated<br />

<strong>Hypertension</strong><br />

Beom‐June Kwon, Sung‐Won Jang, Kyu‐Young Choi,<br />

Dong‐Bin Kim, Eun‐Joo Cho, Ho‐Joong Youn, Tae‐Ho<br />

Rho, Jae‐Hyung Kim. The Catholic University <strong>of</strong><br />

Korea, Seoul, KR.<br />

Comprehensive multi-level interventions<br />

for hypertension management in highrisk<br />

groups<br />

PO-11:<br />

PO-12:<br />

PO-13:<br />

PO-14:<br />

PO-15:<br />

Refractory <strong>Hypertension</strong> Characterized by<br />

Heightened Sympathetic Tone<br />

Maria Czarina Acelajado, 1 Roberto Pisoni, 2 Tanja<br />

Dudenbostel, 3 Suzanne Oparil, 3 David A. Calhoun. 3<br />

1 Philippine General Hospital, Manila, PH; 2 Medical<br />

University <strong>of</strong> South Carolina, Charleston, SC, US;<br />

3 University <strong>of</strong> Alabama at Birmingham, Birmingham,<br />

AL, US.<br />

Prehypertension has Increased Peripheral Resistance<br />

in Patients with Obesity<br />

Ricardo M. Cabrera Sole, 1 Caridad Turpin Lucas, 1 Erik<br />

Luepke, 2 Santiago Garcia Ruiz, 1 Santos J. Martinez. 1<br />

1 University General Hospital <strong>of</strong> Albacete, Albacete, ES;<br />

2 University General Hospital “La Paz”, Madrid, ES.<br />

Some Fixed Combinations are Better Reducing<br />

Central Blood Pressure and Hypertensive Time than<br />

Others<br />

Ricardo M. Cabrera Sole, 1 Caridad Turpin Lucas, 1<br />

Santiago Garcia Ruiz, 1 Ana Galdamez Nuñez, 2 Erik<br />

Luepke, 3 Manuel Aguilera Saldaña. 1 1 University<br />

General Hospital <strong>of</strong> Albacete, Albacete, ES; 2 Health<br />

Center <strong>of</strong> Villacerrada, Albacete, ES; 3 University<br />

General Hospital “La Paz”, Madrid, ES.<br />

Prevalence <strong>of</strong> Orthostatic Hypotension among Very<br />

Elderly Persons with <strong>Hypertension</strong><br />

Elaine Ku, 1 Yee Lu, 1 Edward Schneider, 1 Rick Smith, 2<br />

Vito M. Campese. 1 1 USC/Keck School <strong>of</strong> Medicine, Los<br />

Angeles, CA, US; 2 Los Angeles Jewish Home for the<br />

Aging, Reseda, CA, US.<br />

Effects <strong>of</strong> Renal Stenting on Renal and Cardiac<br />

Outcomes in Patients with Resistant <strong>Hypertension</strong><br />

Cristiana Catena, GianLuca Colussi, Frine Capobianco,<br />

Stefania Fedrizzi, Leonardo A. Sechi. University <strong>of</strong><br />

Udine, Udine, IT.<br />

88


Saturday Afternoon MAY 21<br />

Posters<br />

PO-16:<br />

PO-17:<br />

PO-18:<br />

PO-19:<br />

PO-20:<br />

PO-21:<br />

PO-22:<br />

Evaluation <strong>of</strong> a Treatment Algorithm Using<br />

Combination Therapy for the Management<br />

<strong>of</strong> Patients with <strong>Hypertension</strong> and<br />

Hypercholesterolemia (STITCH2)<br />

G. K. Dresser†, S. A. E. Nelson, J. L. Mahon, G. Y. Zou,<br />

M. K. Vandervoort, C. J. Wong, B. G. Feagan, R. D.<br />

Feldman. Robarts Research Institute, London, CA.<br />

Sex Differences Impact the Hemodynamics <strong>of</strong><br />

Untreated Essential Hypertensive Subjects<br />

Carlos M. Ferrario, 1,2 Ronald D. Smith. 1 1 Consortium<br />

Southeastern <strong>Hypertension</strong> Control, Winston Salem,<br />

NC, US; 2 Wake Forest University School <strong>of</strong> Medicine,<br />

Winston Salem, NC, US.<br />

Improving Global Vascular Risk Management Using<br />

the COSEHC Cardiovascular Risk Assessment Tool<br />

Carlos M. Ferrario†, 1,2 Michael A. Moore, 1 Debra<br />

Simmons, 1,2 Chris Colby, 3 Alex Exuzides, 3 Sumeet<br />

Panjabi. 4 1 Consortium for Southeastern <strong>Hypertension</strong><br />

Control, Winston Salem, NC, US; 2 Wake Forest<br />

University School <strong>of</strong> Medicine, Winston Salem, NC,<br />

US; 3 ICON Clinical Research, San Francisco, CA, US;<br />

4 Daiichi Sankyo, Inc., Parsippany, NJ, US.<br />

A COSEHC Sponsored Quality Improvement<br />

Initiative Enriches Chronic Disease Practice and<br />

Performance <strong>of</strong> North Carolina Diabetic Patients<br />

Mazen Hamad, 1 Brian Forrest, 2 Michael Moore, 2<br />

Debra Simmons, 2 JaNae Joyner. 2 1 Cary Healthcare<br />

Associates, Cary, NC, US; 2 The Consortium for<br />

Southeastern <strong>Hypertension</strong> Control (COSEHC),<br />

Winston Salem, NC, US.<br />

Cardiovascular Care Disparities in a South Carolina<br />

Primary Care Site Participating in the COSEHC<br />

Customized Model <strong>of</strong> Intervention and Care<br />

(COSMIC) Project<br />

JaNae Joyner, 1 Brian Forrest, 1 Kristina Yu‐Isenberg, 2<br />

Debra Simmons, 1 Daniel Lackland. 1 1 The Consortium<br />

for Southeastern <strong>Hypertension</strong> Control (COSEHC),<br />

Winston Salem, NC, US; 2 Novartis Pharmaceuticals<br />

Corporation, US.<br />

Adherence to Comprehensive Interventions for<br />

Management <strong>of</strong> Uncontrolled <strong>Hypertension</strong><br />

Tessa J. Kerby, Stephen E. Asche, Michael V. Maciosek,<br />

JoAnn M. SperlHillen, Simrandeep K. Tiawana,<br />

Patrick J. O’Connor, Karen L. Margolis. HealthPartners<br />

Research Foundation, Minneapolis, MN, US.<br />

Blood Pressure Control in Spanish Speaking<br />

Patients with Type II Diabetes Mellitus Using a<br />

Group Visit Model<br />

Mateo Levine Ledezma, Marie F. Martinez, Scott A.<br />

Rasgon. Kaiser Permanente, Los Angeles, CA, US.<br />

89


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-23:<br />

PO-25:<br />

PO-26:<br />

PO-27:<br />

PO-28:<br />

PO-29:<br />

PO-30:<br />

A Multi-Level Intervention to Control <strong>Hypertension</strong><br />

in African <strong>American</strong>s<br />

Gbenga Ogedegbe, 1 Jonathan Tobin, 2 Joseph Schwartz, 3<br />

Thomas Pickering. 3 1 NYU School <strong>of</strong> Medicine, NY,<br />

NY, US; 2 Clinical Directors Network, NY, NY, US;<br />

3 Columbia University, NY, NY, US.<br />

Physical Characteristics <strong>of</strong> Salt in the Treatment and<br />

Prevention <strong>of</strong> <strong>Hypertension</strong><br />

Maithri Reddy, 1 Podduturu S. Reddy, 2 Sushma Reddy. 1<br />

1 Endocrinology & Diabetes Center, Fort Gratiot, MI,<br />

US; 2 St.Clair Pulmonary & Critical Care, Port Huron,<br />

MI, US.<br />

Relation between Cardiovascular Risk Score,<br />

Asymptomatic Peripheral Disease and Left<br />

Ventricular Hypertrophy<br />

Juan José Tamarit‐García, 1 Belén Roig‐Espert, 2 Vicente<br />

Navarro‐Ibáñez. 2 1 Dr. Peset Universitary Hospital,<br />

Valencia, ES; 2 Manises Hospital, Manises, Valencia, ES.<br />

A Computer-Mediated Intervention and D<strong>ASH</strong> Diet,<br />

WHEELS-I <strong>Program</strong>, Sustains Improved Blood<br />

Pressure over 8 Weeks in Women from Diverse<br />

Ethnic Backgrounds<br />

Margaret Scisney‐Matlock, 1 Susan Steigerwalt, 2<br />

Kenneth Jamerson, 1 Stephanie Lucas, 3 Susan Pressler, 1<br />

Amanda Sen, 1 Elizabeth Brough. 1 1 University <strong>of</strong><br />

Michigan, Ann Arbor, MI, US; 2 St. John Health<br />

System, Detroit, MI, US; 3 Center Preventative<br />

Medicine, St Clair Shores, MI, US.<br />

Relationships between Aggressive Systolic BP Goals,<br />

Nocturnal BP Dipping, and Carotid Atherosclerosis<br />

in Type 2 Diabetes: The SANDS Study<br />

Angela Silverman, 3 Mihriye Mete, 3 Jerome L. Fleg, 2<br />

Marie Russell, 1 Robert E. Ratner, 3 Mary J. Roman, 4<br />

Mario Stylianou, 2 Jason G. Umans, 3 Matthew R.<br />

Weir, 5 Barbara V. Howard. 3 1 Phoenix Indian Medical<br />

Center, US; 2 National Heart, Lung, and Blood Institute,<br />

US; 3 MedStar Health Research Institute, US; 4 Weill<br />

Medical College <strong>of</strong> Cornell University, US; 5 University<br />

<strong>of</strong> Maryland School <strong>of</strong> Medicine, US.<br />

Improved <strong>Hypertension</strong> Control Rates through a<br />

Multidisciplinary Regional Approach<br />

Ann M. Wells, Stephanie C. Schneider, Jennifer Bajaj,<br />

Susan Schreiner, Beverly Kroner. Kaiser Permanente<br />

Colorado, Denver, CO, US.<br />

Clinical Pharmacist-Physician Team Approach in<br />

Treating Resistant <strong>Hypertension</strong> Cases<br />

Sandra A. Yoo, Joel Handler, Alec V. Does. Kaiser<br />

Permanente, Anaheim, CA, US.<br />

90


Saturday Afternoon MAY 21<br />

Posters<br />

Endothelial Function<br />

PO-31:<br />

PO-32:<br />

PO-33:<br />

PO-34:<br />

PO-35:<br />

PO-37:<br />

PO-38:<br />

PO-39:<br />

A Novel ANP-Like Peptide, ANP1-28RR, Revealed<br />

by a Single Nucleotide Polymorphism <strong>of</strong> the ANP<br />

Gene, rs5065 Codes for a Peptide with Increased<br />

Permeability Properties In Vitro<br />

Valentina Cannone, Brenda K. Huntley, Guido<br />

Boerrigter, Alessandro Cataliotti, Denise M. Heublein,<br />

John C. Burnett. Mayo Clinic, Rochester, MN, US.<br />

Exaggerated Exercise Blood Pressure Response<br />

is Associated with Arterial Stiffness, Asymmetric<br />

Dimethylarginine and Osteoprotegerin in Essential<br />

<strong>Hypertension</strong><br />

K. Dimitriadis, C. Tsioufis, A. Aggelis, A. Michaelides,<br />

S. Aslam, C. Wilcox, V. Papademetriou, C. Stefanadis.<br />

Hippokration Hospital, Athens, GR.<br />

Endothelial Impact <strong>of</strong> Blood Pressure above the<br />

Goals in Hypertensive Patients<br />

Jose Saban‐Ruiz, Martin Fabregate, Rosa Fabregate,<br />

Olivia Sanchez, Susana Tello, Angelica Fernandez,<br />

Nuria De la Torre, Arantxa Rodriguez. Ramon y Cajal<br />

Hospital, Madrid, ES.<br />

Plasma Sodium but Not Sodium to Potassium Ratio<br />

Could be a Simple and Low-Cost Technique to<br />

Predict Vascular Inflammation. Correlation with<br />

Resistin Levels<br />

Martin Fabregate, Rosa Fabregate, Nuria De la Torre,<br />

Cristina Martinez, Arantxa Rodriguez, Ana Alonso,<br />

Carlos Moreno, Jose Saban‐Ruiz. Ramon y Cajal<br />

Hospital, Madrid, ES.<br />

Time for Action. Correlation between Plasma Renin<br />

Activity and Biomarkers. A Mandatory Study as<br />

Result <strong>of</strong> a Recent Heart Outcomes Prevention<br />

Evaluation Analysis<br />

Jose Saban‐Ruiz, Martin Fabregate, Rosa Fabregate,<br />

Elena Tutor, Elena Castresana, Nuria De la Torre,<br />

Juanjo Villafruela, Susana Tello, Arantxa Rodriguez.<br />

Ramon y Cajal Hospital, Madrid, ES.<br />

Variability <strong>of</strong> Flow Mediated Dilation Technique: A<br />

Multicentre Italian Study<br />

Francesco Faita, Lorenzo Ghiadoni, Vincenzo<br />

Gemignani, Elisabetta Bianchini, Almerina Biggi,<br />

Giuseppe Ambrosio, Gaetano A. Lanza, Maria Lorenza<br />

Muiesan, Francesco Cosentino, Stefano Taddei.<br />

Working Group on Endothelium <strong>of</strong> the Italian <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong>, IT.<br />

Endothelial Dysfunction in Hypertensive Patients<br />

with Metabolic Syndrome<br />

Olga Gonzalez‐Albarran, Sara Calvo, Marta Carrasco,<br />

Marta Cano, Berniza Calderon, Ana Maria Matei.<br />

Hospital Ramón y Cajal, Madrid, ES.<br />

Normative Brachial Artery Diameter Dilatation<br />

Following Reactive Hyperemia<br />

Martha A. Kaeser, Daniel W. Haun, Norman W.<br />

Kettner. Logan College <strong>of</strong> Chiropractic, Chesterfield,<br />

MO, US.<br />

91


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-40:<br />

PO-41:<br />

PO-42:<br />

PO-43:<br />

PO-44:<br />

PO-45:<br />

Severity <strong>of</strong> Obstructive Sleep Apnea and<br />

Atherosclerosis: Multiple Associations in the Setting<br />

<strong>of</strong> <strong>Hypertension</strong><br />

A. Kasiakogias, C. Tsioufis, C. Thomopoulos, I.<br />

Andrikou, M. Almiroudi, I. Mpafakis, K. Kintis, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Modulation <strong>of</strong> Vascular Function and Oxidative<br />

Stress in Type II Diabetes Mellitus: Effects <strong>of</strong> Alpha-<br />

Lipoic Acid<br />

Bobby V. Khan†, 1 Tahir Haque, 1 Desikan Rajagopal, 1<br />

Nadya Merchant, 1 Barry Connell, 2 Tarek M. Saleh. 2<br />

1 Atlanta Vascular Research Foundation, Atlanta,<br />

GA, US; 2 University <strong>of</strong> Prince Edward Island,<br />

Charlottetown, PE, CA.<br />

Atherogenic Index <strong>of</strong> the Plasma as Marker <strong>of</strong><br />

Oxidative Stress and Endothelial Dysfunction<br />

Rosa Fabregate, Arantxa Rodriguez, Martin Fabregate,<br />

Elena Marin, Andres Reyes, Cristina Martinez, Susana<br />

Tello, Nuria De la Torre, Jose Saban‐Ruiz. Ramon y<br />

Cajal Hospital, Madrid, ES.<br />

The Effect <strong>of</strong> Angiotensin Converting Enzyme<br />

Inhibitors and Angiotensin-II Receptor Antagonists<br />

on the Endothelial Dysfunction in Patients<br />

with Chronic Pulmonary Heart with Arterial<br />

<strong>Hypertension</strong><br />

Nestor M. Seredyuk, Igor P. Vakalyuk, Vitaliy N.<br />

Seredyuk, Sergiy V. Fedorov. Ivano-Frankivsk National<br />

Medical University, Ivano-Frankivsk, UA.<br />

Associations <strong>of</strong> Renal Flow Reserve with Endothelial<br />

Dysfunction in Essential Hypertensives<br />

C. Tsioufis, D. Tsiachris, I. Tatsis, K. Dimitriadis, D.<br />

Syrseloudis, I. Kallikazaros, V. Papademetriou, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Increased Endothelin-1 Vasoconstrictor Tone with<br />

Prehypertension<br />

Brian R. Weil, 1 Michael L. Mestek, 1 Jared J. Greiner, 1<br />

Brian L. Stauffer, 2 Christopher A. DeSouza. 1<br />

1 University <strong>of</strong> Colorado at Boulder, Boulder, CO,<br />

US; 2 University <strong>of</strong> Colorado Denver and the Health<br />

Sciences Center, Aurora, CO, US.<br />

Epidemiology/Special Populations<br />

PO-46:<br />

Management <strong>of</strong> Hypertensive Patients in France<br />

as a Function <strong>of</strong> Gender and Cardiovascular Risk:<br />

PARITE Study<br />

Simon Tabassome, 1 Claire Mounier‐Vehier, 2<br />

Dominique Guedj, 3 Assya Achouba, 4 Emmanuel<br />

Ghannad, 5 Stéphane Quéré, 4 Maxime Guenoun. 6<br />

1 CHU Saint-Antoine, Paris, FR; 2 Cardiologic Hospital,<br />

Lille, FR; 3 Cardiologist, Paris, FR; 4 Novartis Pharma<br />

SAS, Paris, FR; 5 Cardiologist, Gif sur Yvette, FR;<br />

6 Cardiologist, Marseille, FR.<br />

92


Saturday Afternoon MAY 21<br />

Posters<br />

PO-47:<br />

PO-48:<br />

PO-49:<br />

PO-50:<br />

PO-51:<br />

PO-52:<br />

PO-53:<br />

PO-54:<br />

The Relationship <strong>of</strong> Resistant <strong>Hypertension</strong> and<br />

Treatment Outcomes with Total Compliance and<br />

Brain Natriuretic Peptide in an African <strong>American</strong><br />

Hypertensive Cohort<br />

Omid Bakhtar, Brian A. Ference, Phillip D. Levy,<br />

Samar A. Nasser, Lowell Hedquist, John M. Flack.<br />

Division <strong>of</strong> Translational Research and Clinical<br />

Epidemiology, Wayne State University, Detroit Medical<br />

Center, Detroit, MI, US.<br />

Which Ambulatory Blood Pressure Monitoring<br />

Parameters Predict Mortality in Elderly Subjects<br />

Iddo Z. Ben‐Dov, 1 Michael Bursztyn. 2 1 The Rockefeller<br />

University, New York, NY, US; 2 Hadassah – Hebrew<br />

University Medical Center, Jerusalem, IL.<br />

Birth Weight, Stimulus Response and Hemodynamic<br />

Variability Implicates Ethnic Contrasts <strong>of</strong><br />

Autonomic Control <strong>of</strong> Heart Rate and Blood<br />

Pressure and an Effect on CV Disease<br />

Wei Chen, Pronabesh DasMahapatra, Camilo<br />

Fernandez, Gerald S. Berenson. Tulane University<br />

Health Sciences Center, New Orleans, LA, US.<br />

Changes in Levels <strong>of</strong> Serum Cholesterol and<br />

Development <strong>of</strong> <strong>Hypertension</strong> in the Brisighella<br />

Heart Study<br />

Claudio Borghi, Ada Dormi, Sergio d’Addato, Arrigo<br />

Cicero, Luca Laghi, Eugenio Roberto Cosentino,<br />

Maddalena Veronesi. St. Orsola-Malpighi Hospital,<br />

Bologna, IT.<br />

Alcohol Consumption and the Risk <strong>of</strong> <strong>Hypertension</strong>:<br />

A Systematic Review and Meta-Analysis<br />

Alex Briasoulis, Vikram Agarwal, Manpreet S.<br />

Sabharwal, George Syros, Girish N. Nadkarni, Franz<br />

H. Messerli. St. Luke’s-Roosevelt Hospital Center,<br />

Columbia University College <strong>of</strong> Physicians and<br />

Surgeons, New York, NY, US.<br />

Trends in Albuminuria under RAS Suppression and<br />

Relationship with Cardiovascular Disease<br />

Cesar Cerezo, 1 Julian Segura, 1 Jose R. Banegas, 2 Juan<br />

J. de la Cruz, 2 Ton J. Rabelink, 3 Luis M. Ruilope. 1<br />

1 Hospital 12 de Octubre, Madrid, ES; 2 Universidad<br />

Autónoma, Madrid, ES; 3 Leiden University Medical<br />

Center, Leiden, NL.<br />

Large Change in the Opinon on Antihypertensive<br />

Drug Treatment among General Practioners in<br />

Sweden between 2002 and 2009<br />

John K. F. Dahlström, Mats Persson, Bo Carlberg,<br />

Lars‐Hjalmar Lindholm. Family Medicine, Umeå, SE.<br />

Novel Method for Assessing the Prevalence <strong>of</strong><br />

<strong>Hypertension</strong> and Cardiovascular Disease Risk in<br />

a Community Screening <strong>Program</strong> in a South East<br />

Region <strong>of</strong> US<br />

Mahfouz El Shahawy, 1 Miglena Entcheva, 1 Susan<br />

Gaida, 1 Joshua Grant. 2 1 Sarasota Memorial Hospital,<br />

Sarasota, FL, US; 2 Lake Erie College <strong>of</strong> Osteopathic<br />

Medicine, US.<br />

93


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-55:<br />

PO-56:<br />

PO-57:<br />

PO-58:<br />

PO-59:<br />

PO-60:<br />

PO-61:<br />

Pre-<strong>Hypertension</strong>: Is it a Disease<br />

Mahfouz El Shahawy, 1 Miglena Entcheva, 1 Susan<br />

Gaida, 1 Joshua Grant. 2 1 Sarasota Memorial Hospital,<br />

Sarasota, FL, US; 2 Lake Erie College <strong>of</strong> Osteopathic<br />

Medicine, US.<br />

Exercise Capacity Predicts Progression from Pre-<br />

<strong>Hypertension</strong> to <strong>Hypertension</strong> in African <strong>American</strong><br />

Men<br />

Charles Faselis, 1,2 Raya Kheirbek, 1 Michael Doumas, 1,2<br />

Ross Fletcher, 1 Vasilios Papademetriou, 1,3 Peter<br />

Kokkinos. 1,2,3 1 Veterans Affairs Medical Center,<br />

Washington, DC, US; 2 George Washington University,<br />

Washington, DC, US; 3 Georgetown University,<br />

Washington, DC, US.<br />

Biracial (Black-White) Divergence and Correlates<br />

<strong>of</strong> Augmentation Index among Younger Adults: The<br />

Bogalusa Heart Study<br />

Camilo Fernandez, Pronabesh DasMahapatra, Wei<br />

Chen, Sathanur R. Srinivasan, Gerald S. Berenson.<br />

Tulane University Health Sciences Center, New<br />

Orleans, LA, US.<br />

Use <strong>of</strong> Electronic Health Records to Evaluate<br />

<strong>Hypertension</strong> Pharmacoepidemiology in a Primary<br />

Care Practice Network<br />

Christopher Hebert†, Rustam Kudyakov, Yahya Daoud,<br />

Dunlei Cheng, Andrew Masica. Baylor Health Care<br />

System, Dallas, TX, US.<br />

Cardiovascular Risk Factors Prevalence in Greek<br />

Hypertensives Stratified by Gender and Age<br />

Gregory Vyssoulis, 1 Eva Karpanou, 2 Stella Maria<br />

Kyvelou, 1 M. Liakos, 1 C. Stefanadis. 1 1 1st Cardiology<br />

Clinic Athens University Hippokration Hospital, GR;<br />

2 1st Cardiology Clinic Onassis Cardiosurgery Center,<br />

GR.<br />

ABO and Rhesus Blood Groups and Cardiovascular<br />

Risk in Essential Hypertensive Patients<br />

Stella Maria Kyvelou, 1 Gregory Vyssoulis, 1 Eva<br />

Karpanou, 2 T. Gialernios, 1 C. Stefanadis. 1 1 1st<br />

Cardology Clinic Athens University Hippokration<br />

Hospital, GR; 2 1st Cardiology Clinic Onassis<br />

Cardiosurgery Center, GR.<br />

Efficacy, Safety and Tolerability <strong>of</strong> Valsartan/<br />

Hydrochlorothiazide Single Pill Combination in<br />

Asian Patients with Essential <strong>Hypertension</strong>: An<br />

Observational Study<br />

Wen‐Ter Lai†, 1 Jeong‐Euy Park, 2 Neelesh Dongre, 3<br />

Jackson Wang. 3 1 Kaohsiung Medical University<br />

Hospital, Kaohsiung, TW; 2 Samsung Medical Center,<br />

Irwon-dong, Gangnam-gu, Seoul, KR; 3 Novartis<br />

Pharma AG, Basel, CH.<br />

94


Saturday Afternoon MAY 21<br />

Posters<br />

PO-62:<br />

PO-63:<br />

PO-64:<br />

PO-65:<br />

PO-66:<br />

PO-67:<br />

PO-68:<br />

PO-69:<br />

PO-70:<br />

Trends in Serum Lipids, <strong>Hypertension</strong>, Physician<br />

Advice and Compliance among Reproductive-<br />

Aged Women: United States National Health and<br />

Nutrition Examination Survey 1999-2008<br />

Tabassum H. Laz, Mahbubur Rahman, Abbey B.<br />

Berenson. University <strong>of</strong> Texas Medical Branch,<br />

Galveston, TX, US.<br />

Excessive Blood Pressure Elevation during Exercise<br />

Correlates with Low Fitness among Normotensive<br />

Firefighters<br />

Adi Leiba, 1,2 Dorothee M. Baur, 1,3 Stefanos N. Kales. 1,3<br />

1 Harvard School <strong>of</strong> Public Health, Boston, MA, US;<br />

2 Sheba Medical Center, Tel Hashomer, IL; 3 Cambridge<br />

Health Alliance, Cambridge, MA, US.<br />

Smoking and <strong>Hypertension</strong>: Do They Follow the<br />

Same Trend<br />

Aurelio Leone. City Hospital, Massa, Ms, IT.<br />

Arterial <strong>Hypertension</strong> and Liver Cirrhosis: The<br />

Experience <strong>of</strong> a Single Liver Unit<br />

Simona Leoni, Serena Flori, Barbara Stagni, Ilaria<br />

Serio, Luigi Bolondi. Malpighi Hospital, Division <strong>of</strong><br />

Internal Medicine Pr<strong>of</strong>. Bolondi, Bologna, IT.<br />

Blood Pressure Control and Age: The Experience <strong>of</strong><br />

a Single Centre<br />

Serena Flori, Simona Leoni, Barbara Stagni, Ilaria<br />

Serio, Luigi Bolondi. Malpighi Hospital, Division <strong>of</strong><br />

Internal Medicine, Bologna, IT.<br />

The Effect <strong>of</strong> C<strong>of</strong>fee on Blood Pressure and<br />

Cardiovascular Disease among Hypertensive<br />

Individuals: Meta-Analysis<br />

Arthur E. Mesas, Luz Leon‐Muñoz, Fernando<br />

Rodriguez‐Artalejo, Esther Lopez‐Garcia. Autonoma<br />

University <strong>of</strong> Madrid, Madrid, ES.<br />

Mechanisms Underlying Increased Aortic BP in<br />

Black Versus White Young Adults: The ENIGMA<br />

Study<br />

Carmel M. McEniery, 1 Andrew T. Garrett, 2 Nigel<br />

Baber, 2 John R. Cockcr<strong>of</strong>t, 3 Ian B. Wilkinson. 1<br />

1 University <strong>of</strong> Cambridge, Cambridge, GB; 2 University<br />

<strong>of</strong> Hertfordshire, GB; 3 Cardiff University, GB.<br />

Diabetes Type 2 and Other Cardiovascular Risk<br />

Factors in an Adult Mediterranean Population<br />

Javier Nieto, 1 Patricio Giralt, 2 Maria Jose Ballesteros, 1<br />

G. Gutierrez, 3 Carmen Mora, 1 Agustin Carreño. 1<br />

1 Hospital General, Ciudad Real, ES; 2 Fundacion<br />

Sociosanitaria, Ciudad Real, Castilla La Mancha, ES;<br />

3 Consejería de Salud, Toledo, ES.<br />

Serum Uric Acid is an Independent Risk Factor for<br />

Cardiovascular Diseases Mortality in Hypertensive<br />

Patients<br />

Mitsuru Ohishi, Yasushi Takeya, Miyuki Onishi, Yuji<br />

Tatara, Kei Kamide, Hiromi Rakugi. Osaka University,<br />

Suita, Osaka, JP.<br />

95


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-71:<br />

PO-72:<br />

PO-73:<br />

PO-74:<br />

PO-75:<br />

PO-76:<br />

PO-77:<br />

Blood Pressure Control and All Cause Mortality in<br />

Old and Very Old Patients with <strong>Hypertension</strong><br />

Vasilios Papademetriou, Richard Amdur, Charles<br />

Faselis, Michael Doumas, Costas Tsioufis, Peter<br />

Kokkinos, Ross D. Fletcher. Veterans Administration<br />

and Georgetown University Medical Centers<br />

Washington DC, Washington, DC, US.<br />

Ambulatory Blood Pressure Monitoring Pr<strong>of</strong>ile in<br />

Untreated African Blacks and Causasians Untreated<br />

Hypertensive Patients Matched for Age and Gender<br />

Albertino Damasceno, 1 C. Mavimbe, 1 Loide Barbosa, 2<br />

Jose A. Silva, 2 Domingos Diogo, 1 T. Madede, 1 Jorge<br />

Polonia. 2 1 Universidade Eduardo Mondlane, Maputo,<br />

MZ; 2 Hospital Pedro Hispano, Matosinhos, PT.<br />

Regional Differences in Hypertensive<br />

Cardiovascular Remodeling between Fishing and<br />

Farming Communities in Japan<br />

Koji Sakata, 1 Yuichiro Yano, 2 Takuro Imamura, 1 Kazuo<br />

Kitamura, 1 Kazuomi Kario. 2 1 University <strong>of</strong> Miyazaki,<br />

JP; 2 Jichi Medical University School <strong>of</strong> Medicine, JP.<br />

Relevance <strong>of</strong> Atrial Fibrillation in a Large Cohort <strong>of</strong><br />

Hypertensive Patients<br />

Julian Segura, 1 Vanesa Moñivas, 1,2 Jose A. Garcia-<br />

Donaire, 1 Cesar Cerezo, 1 Luis M. Ruilope. 1 1 Hospital<br />

12 de Octubre, Madrid, ES; 2 Hospital Puerta de Hierro,<br />

Madrid, ES.<br />

Periodontal Disease Severity and Albumin Excretion<br />

in Hypertensive Patients: A Positive Association<br />

Beyond Systemic Inflammation<br />

C. Tsioufis, A. Kasiakogias, C. Thomopoulos, N.<br />

Soldatos, A. Kordalis, M. Almiroudi, K. Kintis, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Efficacy <strong>of</strong> Amlodipine/Olmesartan Medoxomil with<br />

or without Hydrochlorothiazide in Elderly Patients<br />

Uncontrolled by Monotherapy<br />

Matthew R. Weir†, 1 Henry A. Punzi, 2 Ali Shojaee, 3<br />

William F. Waverczak, 3 Jen‐Fue Maa. 3 1 University<br />

<strong>of</strong> Maryland School <strong>of</strong> Medicine, US; 2 Trinity<br />

<strong>Hypertension</strong> & Metabolic Research Institute, US;<br />

3 Daiichi Sankyo, Inc., US.<br />

Blood Pressure Therapy and Risk <strong>of</strong> CVD:<br />

Framingham Heart Study Experience<br />

Peter W. F. Wilson†, 1 Michael Pencina, 2 Ralph B.<br />

D’Agostino, 2 Asya Lyass, 2 R. S. Vasan, 2 Philip A. Wolf, 2<br />

Daniel Levy. 3 1 Emory University, Atlanta, GA, US;<br />

2 Boston University, Boston, MA, US; 3 Framingham<br />

Heart Study, Framingham, MA, US.<br />

96


Saturday Afternoon MAY 21<br />

Posters<br />

Immune mechanisms in hypertension<br />

PO-79:<br />

PO-80:<br />

PO-81:<br />

PO-82:<br />

Renal Specific Silencing <strong>of</strong> Dopamine D 2 Receptors<br />

in Mice Increases Blood Pressure and Pro-<br />

Inflammatory Factors<br />

Ines Armando, Santiago Cuevas, Yanrong Zhang,<br />

Laureano Asico, Crisanto Escano, Pedro A. Jose.<br />

Children’s National Medical Center, Washington, DC,<br />

US.<br />

Macrophages Regulate Pressor Responses to<br />

Endothelin-1<br />

E. L. Owen, N. Dhaun, M. Bailey, D. J. Webb, D. C.<br />

Kluth. University <strong>of</strong> Edinburgh, GB.<br />

BMI Influences the Association <strong>of</strong> an IL-6<br />

Polymorphism on Increased Insulin Resistance in a<br />

Hypertensive Population<br />

P. Underwood, 1 B. Chamarthi, 1 J. Williams, 1 B. Sun, 1<br />

P. Hopkins, 2 G. Adler, 1 G. Williams. 1 1 Brigham and<br />

Women’s Hospital, US; 2 University <strong>of</strong> Utah, US.<br />

Correlation between Endothelial Dysfunction and<br />

Inflammatory Markers at the Chronic Heart Failure<br />

with Arterial <strong>Hypertension</strong><br />

Roman I. Yatsyshyn, Natalya G. Yatsyshyn. Medical<br />

University, Ivano-Frankivsk, UA.<br />

Metabolic Syndrome (Diabetes/Glycemic<br />

Control; Dysglycemic Drugs; Insulin<br />

Resistance)<br />

PO-83:<br />

PO-84:<br />

PO-85:<br />

Screening for Diabetes in a Developing Country<br />

Olutayo Christopher Alebiosu, 1 Olawale Ogunsemi, 2<br />

Olatunde Odusan, 2 Oluranti Familoni. 2 1 College <strong>of</strong><br />

Health Sciences, Osun State University, Osogbo, Osun,<br />

NG; 2 Olabisi Onabanjo University, Sagamu Campus,<br />

Ogun State, NG.<br />

Metabolic Pr<strong>of</strong>ile and Framingham Heart Scores<br />

among Hypertensives in Turkey from 2003 to 2007<br />

Mustafa Arici, 1 Ulver Derici, 2 Cetin Turgan, 1 Yunus<br />

Erdem, 1 Sukru Sindel, 2 Bulent Altun, 1 Bulent Erbay, 3<br />

Oktay Karatan, 3 Enver Hasanoglu, 2 Sali Caglar. 4<br />

1 Hacettepe University Faculty <strong>of</strong> Medicine, Ankara,<br />

TR; 2 Gazi University Faculty <strong>of</strong> Medicine, Ankara, TR;<br />

3 Ankara University Faculty <strong>of</strong> Medicine, Ankara, TR;<br />

4 Turkish <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> and Renal Diseases,<br />

Ankara, TR.<br />

Gender-Independent Elevation <strong>of</strong> Fasting Glucose<br />

with the Progressive Decrease in Sleep-Time<br />

Relative Blood Pressure Decline: The Hygia Project<br />

Diana E. Ayala, 1 Juan J. Crespo, 2 Ana Moya, 3 Pedro A.<br />

Callejas, 2 Peregrina Eiroa, 2 Alfonso Otero, 4 Artemio<br />

Mojon, 1 Jose R. Fernandez, 1 Ramon C. Hermida, 1<br />

Investigadores Proyecto Hygia. 1 1 University <strong>of</strong> Vigo,<br />

Vigo, ES; 2 Gerencia de Atención Primaria, Vigo, ES;<br />

3 Gerencia de Atención Primaria, Pontevedra, ES;<br />

4 Complejo Hospitalario Universitario, Orense, ES.<br />

97


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-86:<br />

PO-87:<br />

PO-88:<br />

PO-89:<br />

PO-90:<br />

PO-91:<br />

PO-92:<br />

First-Line Aliskiren/HCTZ Lowers BP in Older<br />

Patients with Stage 2 <strong>Hypertension</strong> and Metabolic<br />

Syndrome or Diabetes<br />

Jan Basile†, 1 Simon Babazadeh, 2 Michael Lillestol, 3<br />

Thomas Severin, 4 Cheraz Cherif Papst, 4 Richard<br />

Weitzman. 5 1 Ralph H Johnson VA Medical Center,<br />

Medical University <strong>of</strong> South Carolina, Charleston,<br />

SC, US; 2 Crest Clinical Trials Inc, Santa Ana, CA, US;<br />

3 Lillestol Research LLC, Fargo, ND, US; 4 Novartis<br />

Pharma AG, Basel, CH; 5 Novartis Pharmaceuticals<br />

Corporation, East Hanover, NJ, US.<br />

Effects <strong>of</strong> Time <strong>of</strong> Day <strong>of</strong> <strong>Hypertension</strong> Treatment<br />

on the Ambulatory Blood Pressure Pattern <strong>of</strong><br />

Patients with Diabetes: The Hygia Project<br />

Juan J. Crespo, 1 Manuel Dominguez‐Sardiña, 1<br />

Maria T. Rios, 1 Ana Moya, 2 Sonia M. Gomara, 2 Luis<br />

Meijide, 2 Artemio Mojon, 3 Diana E. Ayala, 3 Ramon C.<br />

Hermida, 3 Investigadores Proyecto Hygia. 3 1 Gerencia<br />

de Atención Primaria, Vigo, ES; 2 Gerencia de Atención<br />

Primaria, Pontevedra, ES; 3 University <strong>of</strong> Vigo, Vigo,<br />

ES.<br />

Overweight and High Blood Pressure as the<br />

Cardiometabolic Risk Factors Most Frequently<br />

Related to Nonalcoholic Fatty Liver Disease<br />

Susana Tello, Angelica Fernandez, Asuncion Guerri,<br />

Rosa Fabregate, Martin Fabregate, Jose Campoy, Arturo<br />

Ugalde, Jose Saban‐Ruiz. Ramon y Cajal Hospital,<br />

Madrid, ES.<br />

Myeloperoxidase, Leptin and Retinol Binding<br />

Protein 4, as Biomarkers <strong>of</strong> Osteopenia and<br />

Atherosclerosis, Two Sister-Diseases<br />

Rosa Fabregate, Olivia Sanchez, Elena Marin, Andres<br />

Reyes, Cristina Martinez, Susana Tello, Martin<br />

Fabregate, Arantxa Rodriguez, Jose Saban‐Ruiz.<br />

Ramon y Cajal Hospital, Madrid, ES.<br />

Unlike Sex, HDL-Cholesterol, Body Mass Index,<br />

Homocysteine and Smoking, Blood Pressure is Not a<br />

Determinant Factor <strong>of</strong> Plasma Leptin Levels<br />

Martin Fabregate, Olivia Sanchez, Rosa Fabregate, Olga<br />

Fernandez, Jose Manuel Del Rey, Susana Tello, Nuria<br />

De la Torre, Elena Tutor, Ana Alonso, Jose Saban‐Ruiz.<br />

Ramon y Cajal Hospital, Madrid, ES.<br />

Salt Sensitive Type 2 Diabetics Have Greater<br />

Metabolic Improvements on a Paleolithic-Type Diet<br />

Compared to an ADA Diet<br />

Lynda A. Frassetto, Olga Schmidlin, Anthony<br />

Sebastian, Umesh Masharani. UCSF, San Francisco,<br />

CA, US.<br />

Impact <strong>of</strong> Gender in Cardiovascular Control in<br />

Hypertensive Patients with Metabolic Syndrome.<br />

OPENMET Survey<br />

Olga Gonzalez, 1 Alberto Galgo, 2 Carlos Alvarez. 3<br />

1 Hospital Ramón y Cajal, Madrid, ES; 2 Primary Care<br />

Center, Madrid, ES; 3 Pfizer Laboratory, Madrid, ES.<br />

98


Saturday Afternoon MAY 21<br />

Posters<br />

PO-93:<br />

PO-94:<br />

PO-95:<br />

PO-96:<br />

PO-97:<br />

PO-98:<br />

PO-99:<br />

Microalbuminuria in Women with Prior Gestational<br />

Diabetes<br />

Olga Gonzalez Albarran, Marta Carrasco, Marta Cano,<br />

Berniza Calderón, Ana Maria Matei. Hospital Ramón y<br />

Cajal, Madrid, ES.<br />

Elevation <strong>of</strong> Blood Suger Changes Glomerular and<br />

Tubular Function in Normotesive Subjects<br />

Shigeo Kakinoki, 1 Tetsuya Fujimoto, 2 Maiko Machida, 2<br />

Shigeru Takechi, 3 Kouichi Kanda, 4 Takeshi Kobayashi, 5<br />

Akikazu Nomura. 2 1 Otaru kyoukai Hospital, Otaru,<br />

Hokkaido, JP; 2 Hokkaido College <strong>of</strong> Pharmacy,<br />

Otaru, Hokkaido, JP; 3 Date Red Cross Hospital, Date,<br />

Hokkaido, JP; 4 Sapporo Kosei General Hospital,<br />

Sapporo, Hokkaido, JP; 5 Hokkaido Social Insurance<br />

Health Care and Research Center, Sapporo, Hokkaido,<br />

JP.<br />

Effects <strong>of</strong> Simvastatin and Rosiglitazone<br />

Combination in Patients with the Metabolic<br />

Syndrome (The SIROCO Study)<br />

Ivana Lazich†, Pantelis A. Sarafidis, Raymond Oliva,<br />

Basil Burney, George Bakris. University <strong>of</strong> Chicago<br />

Pritzker School <strong>of</strong> Medicine, Chicago, IL, US.<br />

Pulse Wave Analysis in Type 2 Diabetic Hypertensive<br />

Patients<br />

Ari L. Lieber, 1 Michel E. Safar, 1 Julie Peroz, 1 Gerard<br />

Slama, 1 Bernard I. Levy, 2 Jacques Blacher. 1 1 Hotel-Dieu<br />

Hospital, Paris, FR; 2 Hopital Lariboisiere, Paris, FR.<br />

Circadian Blood Pressure Pattern and Prevalence<br />

<strong>of</strong> Nocturnal <strong>Hypertension</strong> in Subjects with and<br />

without Type 2 Diabetes: The Hygia Project<br />

Maria C. Castiñeira, 1 Ana Moya, 2 Jesus Perez de Lis, 3<br />

Lorenzo Pousa, 3 Jose L. Salgado, 3 Susana Hernaiz, 3<br />

Artemio Mojon, 4 Jose R. Fernandez, 4 Ramon C.<br />

Hermida, 4 Investigadores Proyecto Hygia. 4 1 Gerencia<br />

de Atención Primaria, Lugo, ES; 2 Gerencia de Atención<br />

Primaria, Pontevedra, ES; 3 Gerencia de Atención<br />

Primaria, Vigo, ES; 4 University <strong>of</strong> Vigo, Vigo, ES.<br />

Influence <strong>of</strong> Sleep-Time Blood Pressure for the<br />

Proper Identification <strong>of</strong> Isolated Office and Masked<br />

<strong>Hypertension</strong> among Patients with Type 2 Diabetes:<br />

The Hygia Project<br />

Ana Moya, 1 Elvira Sineiro, 1 Maria C. Castiñeira, 2<br />

Sonia M. Gomara, 1 Artemio Mojon, 3 Maria J. Fontao, 3<br />

Sonia Lorenzo, 3 Diana E. Ayala, 3 Ramon C. Hermida, 3<br />

Investigadores Proyecto Hygia. 3 1 Gerencia de Atención<br />

Primaria, Pontevedra, ES; 2 Gerencia de Atención<br />

Primaria, Lugo, ES; 3 University <strong>of</strong> Vigo, Vigo, ES.<br />

Suboptimal Control <strong>of</strong> Arterial <strong>Hypertension</strong> in<br />

Patients with Type 2 Diabetes Mellitus<br />

Maria Sarigianni, Eleni Mpekiari, Apostolos Tsapas,<br />

Konstantinos Paletas. Medical School, Aristotle<br />

University <strong>of</strong> Thessaloniki, Thessaloniki, GR.<br />

99


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-100:<br />

PO-101:<br />

PO-102:<br />

Prevalence <strong>of</strong> Metabolic Syndrome According to<br />

Different Definitions in a Mediterranean Cohort <strong>of</strong><br />

Hypertensives<br />

John A. Papadakis, 1 Eirini Lioudaki, 1,2 George E.<br />

Vrentzos, 1 Helen Mavrogeni, 1 Maria‐Helen Zeniodi, 1<br />

Emmanuel S. Ganotakis, 1 Dimitri P. Mikhailidis. 2<br />

1 University Hospital <strong>of</strong> Heraklion, Heraklion, GR;<br />

2 Royal Free Hospital campus, University College<br />

London (UCL) Medical School, London, GB.<br />

Telmisartan Prophylactic Treatment Induces Tissue-<br />

Specific Gene Modulation Favoring Normal Glucose<br />

Homeostasis in CRDH Rats<br />

Firas Younis, 1 Yoram Oron, 1 Rona Limor, 2 Naftali<br />

Stern, 2 Talma Rosenthal. 1 1 Tel Aviv Univeristy, Tel Aviv,<br />

Ramat Aviv, IL; 2 Tel Aviv-Sourasky Medical Center, Tel<br />

Aviv, IL.<br />

Hyperuricemia and the Pathogenesis <strong>of</strong><br />

<strong>Hypertension</strong> and Insulin Resistance in Murine<br />

Model <strong>of</strong> the Metabolic Syndrome<br />

William Baldwin, 1 Steven McRae, 1 George Marek, 1<br />

David Wymer, 1 Varinderpal Pannu, 1 Chris Baylis, 2<br />

Richard J. Johnson, 1,2 Yuri Y. Sautin. 1 1 University <strong>of</strong><br />

Florida, Gainesville, FL, US; 2 University <strong>of</strong> Florida,<br />

Gainesville, FL, US; 3 University <strong>of</strong> Colorado, Denver,<br />

CO, US.<br />

New insights into the role <strong>of</strong> uric acid in<br />

hypertension<br />

PO-103:<br />

PO-104:<br />

Relation <strong>of</strong> Uric Acid with Blood Pressure and<br />

Health Related Quality <strong>of</strong> Life One Year Post<br />

Myocardial Infarction<br />

Antonios Ioannidis, Dimitrios Tsounis. Hellenic Open<br />

University, GR.<br />

<strong>Hypertension</strong> in Hyperuricemic Gout Subjects<br />

Receiving Febuxostat or Allopurinol<br />

Andrew Whelton†, 1,2 Patricia MacDonald, 3 Barbara<br />

Hunt, 3 Lhanoo Gunawardhana. 3 1 Universal Clinical<br />

Research Center, Inc, Hunt Valley, MD, US; 2 Johns<br />

Hopkins University School <strong>of</strong> Medicine, Baltimore,<br />

MD, US; 3 Takeda Global Research & Development<br />

Center, Inc, Deerfield, IL, US.<br />

Pediatric <strong>Hypertension</strong><br />

PO-105:<br />

Systolic and Diastolic Blood Pressures among Sickle<br />

Cell Patients<br />

Guillermo A. De Angulo, 1 Robert J. Adams, 1 Yim<br />

Eunsil, 1 Janet L. Kwiatkowski, 2 Ana C. Xavier, 1 Ellen<br />

Debenham, 1 Jessica A. Peterson, 1 Daniel T. Lackland. 1<br />

1 Medical University <strong>of</strong> South Carolina, Charleston,<br />

SC, US; 2 The Children’s Hospital <strong>of</strong> Philadelphia,<br />

Philadelphia, PA, US.<br />

100


Saturday Afternoon MAY 21<br />

Posters<br />

PO-106:<br />

PO-107:<br />

PO-108:<br />

PO-109:<br />

PO-110:<br />

PO-111:<br />

Antihypertensive Drug Use in Children: Are the<br />

Drugs Labeled and Indicated<br />

Joseph Flynn†, 1 W. Pete Welch, 2 Wenya Yang, 2 Drew<br />

Braucht, 2 Perdita Taylor‐Zapata, 3 Anne Zajicek. 3<br />

1 Seattle Children’s Hospital, Seattle, WA, US; 2 The<br />

Lewin Group, Inc., Falls Church, VA, US; 3 Eunice<br />

Kennedy Shriver National Institute <strong>of</strong> Child Health<br />

and Human Development, Bethesda, MD, US.<br />

Clinical and Demographic Characteristics <strong>of</strong><br />

Children with <strong>Hypertension</strong>: New Multicenter Data<br />

Joseph Flynn†, 1 Ying Zhang, 2 Susan Solar‐Yohay, 2<br />

Victor Shi. 2 1 Seattle Children’s Hospital, Seattle, WA,<br />

US; 2 Novartis Pharma AG, East Hanover, NJ, US.<br />

Cardiovascular Risk Factors in Obese Children and<br />

Adolescents<br />

Isabel Torro, 1,2 Julio Alvarez, 1,2 Francisco Aguilar, 1,2<br />

Jose Alcon, 1,2 Empar Lurbe. 1,2 1 Hospital General<br />

Universitario, University <strong>of</strong> Valencia, Valencia, ES;<br />

2 Health Institute Carlos III, Madrid, ES.<br />

Left Ventricular Geometry in Children with Primary<br />

<strong>Hypertension</strong>: Prevalence and Predictors<br />

Cozumel S. Pruette, 1 Barbara A. Fivush, 1 Joseph T.<br />

Flynn, 2 Tammy M. Brady. 1 1 Johns Hopkins University,<br />

Baltimore, MD, US; 2 Seattle Children’s Hospital,<br />

Seattle, WA, US.<br />

Serum Uric Acid in U.S. Adolescents: Distribution<br />

and Relationship to Demographic Characteristics<br />

and Cardiovascular Risk Factors<br />

Ibrahim F. Shatat, 1 Rany T. Abdallah, 2 David J. Sas, 1<br />

Susan M. Hailpern. 3 1 Medical University <strong>of</strong> South<br />

Carolina Children’s Hospital, Charleston, SC, US;<br />

2 Medical University <strong>of</strong> South Carolina, Charleston, SC,<br />

US; 3 Independent Consultant, Katonah, NY, US.<br />

Clinic and Ambulatory Blood Pressure<br />

Measurements and Patterns in Asymptomatic<br />

Children with Sickle Cell Disease<br />

Ibrahim F. Shatat, 1 Ram V. Kalpatthi, 2 Amanda E.<br />

Blue, 1 Katelyn Graeme, 1 Mary A. Johnson, 1 John K.<br />

Orak, 1 Sharron M. Jackson. 1 1 Medical University <strong>of</strong><br />

South Carolina Children’s Hospital, Charleston, SC,<br />

US; 2 Children’s Mercy Hospital, Kansas City, MO, US.<br />

Risk Factors (Lipids)<br />

PO-112:<br />

Evaluating the Effects <strong>of</strong> Hypercholesterolemia<br />

on Vascular Risk Pr<strong>of</strong>ile <strong>of</strong> Treated Hypertensive<br />

Patients. Results <strong>of</strong> a Cross-Sectional National Study<br />

Pedro Aranda, Manuel Gorostidi, Julian Segura,<br />

Alex de la Sierra, Jose Juan de la Cruz, Jose<br />

Carlos Fernandez, Luis Maria Ruilope. Cardiorisk<br />

Investigators Group, Madrid, ES.<br />

101


MAY 21<br />

Posters<br />

Saturday Afternoon<br />

PO-113:<br />

PO-114:<br />

PO-115:<br />

Negative Influence <strong>of</strong> Hypercholesterolemia on<br />

Blood Pressure Control. Results <strong>of</strong> a Spanish<br />

National Survey with ABPM<br />

Pedro Aranda, Jose Carlos Fernandez, Manuel<br />

Gorostidi, Julian Segura, Alejandro de la Sierra, Jose<br />

Juan de la Cruz, Luis Maria Ruilope. Cardiorisk<br />

Investigators Group, Madrid, ES.<br />

Association <strong>of</strong> Weight Misperception with Abnormal<br />

Lipid Levels and <strong>Hypertension</strong> among Overweight<br />

and Obese Reproductive-Age Women<br />

Mahbubur Rahman, Tabassum H. Laz, Abbey B.<br />

Berenson. University <strong>of</strong> Texas Medical Branch,<br />

Galveston, TX, US.<br />

Influence <strong>of</strong> Metabolic Syndrome Components in<br />

Atherosclerotic Disease and Intima Media Thickness<br />

<strong>of</strong> Carotid Artery Assessed by Gray Scale Method<br />

Priscilla Lopes Sarmento, Frida Liane Plavnik, Sérgio<br />

Aron Ajzen. Federal University <strong>of</strong> Sao Paulo, Sao<br />

Paulo, SP, BR.<br />

Stroke<br />

PO-117: <strong>Hypertension</strong> and Other Co-Morbid Conditions are<br />

Not Determinants <strong>of</strong> Treatment in Acute Ischemic<br />

Stroke<br />

Jordan A. Magarik, Robert J. Adams, Christine A.<br />

Holmstedt, Edward C. Jauch, Andrea D. Boan, Aquilla<br />

S. Turk, Daniel T. Lackland. Medical University <strong>of</strong><br />

South Carolina, Charleston, SC, US.<br />

PO-118: Pr<strong>of</strong>ile <strong>of</strong> Incidental Thyroid Nodules in 2996<br />

Patients Undergoing Carotid Ultrasound<br />

Saxena Naveen, 1 Srivastava Vinita, 1 William Bridges, 2<br />

Ricardo Abaunza, 1 Chanda Craft, 1 Nomita Joshi, 1<br />

Govind Rughani. 1 1 Internal Medicine and Cardiology<br />

Center, Greenville, SC, US; 2 Clemson University,<br />

Clemson, SC, US.<br />

PO-119: Additional Impact <strong>of</strong> Morning Haemostatic Factors<br />

and Blood Pressure Surgeon Stroke in Older<br />

Japanese Hypertensives<br />

Yuichiro Yano, Satoshi Hoshide, Kazuyuki Shimada,<br />

Kazuomi Kario. Jichi Medical University School <strong>of</strong><br />

Medicine, Tochigi, JP.<br />

Vascular Injury/Inflammation and<br />

Remodeling<br />

PO-120:<br />

Non-Dipping Status is Accompanied by<br />

Hypoadiponectinemia and Increased Aortic<br />

Stiffness in Essential <strong>Hypertension</strong><br />

I. Andrikou, C. Tsioufis, D. Syrseloudis, A. Kordalis,<br />

M. Almiroudi, I. Mpafakis, K. Kintis, T. Papaioannou,<br />

D. Aragiannis, C. Stefanadis. Hippokration Hospital,<br />

Athens, GR.<br />

102


Saturday Afternoon MAY 21<br />

Posters<br />

PO-121:<br />

PO-122:<br />

PO-123:<br />

Association <strong>of</strong> Retinal Microvascular Caliber with<br />

Blood Pressure Levels<br />

Raz Gibstein, 1 Yosi Rosman, 2 Ehud Rechtman, 1 Nira<br />

Koren‐Morag, 2 Yehonatan Sharabi, 2 Shlomo Segev, 2<br />

Ehud Assia, 1 Ehud Grossman. 2 1 Meir Hospital, IL; 2 The<br />

Chaim Sheba Medical Center, Tel Hashomer, Affiliated<br />

to Sackler School <strong>of</strong> Medicine, IL.<br />

Inhibiting the Renin-Angiotensin System with<br />

Aliskiren and/or Valsartan Protects Against<br />

C-Reactive Protein Mediated Vascular Injury<br />

Response<br />

Fadi G. Hage†, Caleb Pierce, Wei Zhang, Dongqi<br />

Xing, Yiu‐Fai Chen, Mark A. McCrory, Suzanne<br />

Oparil, Alexander J. Szalai. University <strong>of</strong> Alabama at<br />

Birmingham, Birmingham, AL, US.<br />

High Osteopontin N-Terminal/C-Terminal<br />

Fragment Ratio is Associated with Carotid Plaque<br />

Inflammation<br />

Talya Wolak, 1 Netta Sion‐Vrdy, 1 George Grennberg, 1<br />

Gabriel Szendro, 1 Assaf Rudich, 2 Ori Nov, 2 Victor<br />

Novack, 1 Esther Paran. 1 1 Soroka University Medical<br />

Center, Bear Sheva, IL; 2 Faculty <strong>of</strong> Health Sciences,<br />

Ben-Gurion University <strong>of</strong> the Negev Israel, Bear Sheva,<br />

IL.<br />

103


MAY 22<br />

Posters<br />

Sunday Morning<br />

Posters will be displayed in the Second Floor Promenade.<br />

Sunday, May 22, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 6:30 PM • Poster Viewing: 5:30 PM – 6:30 PM<br />

Featured Posters<br />

Blood Pressure Measurement/Monitoring......................(FP-1 – FP-4)<br />

Adolescent <strong>Hypertension</strong>..................................................(FP-5 – FP-8)<br />

Aldosterone and Anti-Aldosterone Agents..............(PO-124 – PO-130)<br />

Antihypertensive Drugs and Pharmacology............(PO-131 – PO-157)<br />

Clinical Trials................................................................(PO-158 – PO-184)<br />

Coronary Artery Disease............................................(PO-185 – PO-191)<br />

Genetics/Gene Therapy/Proteomics..........................(PO-192 – PO-198)<br />

Heart Failure/Hypertrophy<br />

(Diastolic Dysfunction)...............................................(PO-199 – PO-216)<br />

<strong>Hypertension</strong> in Patients with Chronic<br />

Kidney Disease.............................................................(PO-217 – PO-226)<br />

Kidney and <strong>Hypertension</strong>...........................................(PO-227 – PO-242)<br />

Off-Target Cardiovascular Effects <strong>of</strong><br />

Non-Cardiovascular Drugs........................................(PO-243 – PO-244)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

104


Sunday Morning MAY 22<br />

Posters<br />

10:00 AM – 6:30 PM • Second Floor Promenade<br />

Featured Posters – Blood Pressure<br />

Measurement/Monitoring<br />

Moderators:<br />

FP-1:<br />

FP-2:<br />

FP-3:<br />

FP-4:<br />

Suzanne Oparil, MD, Birmingham, AL and<br />

Talma Rosenthal, MD, Tel Aviv, Israel<br />

Ambulatory Blood Pressure Monitoring and<br />

Cardiovascular Events in High-Risk Patients<br />

Alejandro de la Sierra†, 1 Julian Segura, 2 Jose R.<br />

Banegas, 2 Manuel Gorostidi, 2 Felipe Madruga, 2 Xavier<br />

Clar, 2 Teresa Gijon, 2 Luis M. Ruilope. 2 1 Hospital<br />

Mutua Terrassa, Terrassa, ES; 2 Spanish <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>, Madrid, ES.<br />

A Perfect Replacement for the Mercury<br />

Sphygmomanometer: The Case <strong>of</strong> the Hybrid Blood<br />

Pressure Monitor<br />

George S. Stergiou, Nikos Karpettas, Anastasios Kollias,<br />

Antonis Destounis, Dimitris Tzamouranis. University<br />

<strong>of</strong> Athens, Athens, GR.<br />

Improvement in Blood Pressure Control among<br />

Hypertensive Patients Treated in the Department <strong>of</strong><br />

Veterans Affairs<br />

Ross D. Fletcher, Vasilios Papademetriou, Richard<br />

Amdur, Chris McManus, Ronald Jones, Charles<br />

Faselis. Veterans Affairs and Georgetown University,<br />

Washington, DC, US.<br />

Clinical Characteristics <strong>of</strong> Patients with<br />

Uncontrolled and Apparent Treatment Resistant<br />

<strong>Hypertension</strong>: NHANES 1988-2008<br />

Brent Egan, 1 Yumin Zhao, 1 R. Neal Axon, 1 R. Neal<br />

Axon, 2 Keith Ferdinand. 3 1 Medical University <strong>of</strong><br />

S.C., Charleston, SC, US; 2 Ralph H. Johnson, VAMC,<br />

Charleston, SC, US; 3 Emory University, Atlanta, GA,<br />

US.<br />

105


MAY 22<br />

Posters<br />

Sunday Morning<br />

10:00 AM – 6:30 PM • Second Floor Promenade<br />

Featured Posters – Adolescent<br />

<strong>Hypertension</strong><br />

Moderators:<br />

FP-5:<br />

FP-6:<br />

FP-7:<br />

FP-8:<br />

Daniel I. Feig, MD, PhD, Houston, TX and<br />

Joseph T. Flynn, MD, Seattle, WA<br />

Which BP Measurement Method Best Predicts<br />

Target Organ Damage in Youth<br />

Elaine M. Urbina, 1,2 Philip R. Khoury, 1 Connie E.<br />

McCoy, 1 Stephen R. Daniels, 3 Lawrence M. Dolan, 1,2<br />

Thomas R. Kimball. 1,2 1 Cincinnati Children’s Hospital<br />

Medical Center, Cincinnati, OH, US; 2 University<br />

<strong>of</strong> Cincinnati, Cincinnati, OH, US; 3 University <strong>of</strong><br />

Colorado, Aurora, CO, US.<br />

Effects <strong>of</strong> the D<strong>ASH</strong> Diet on Flow Mediated<br />

Dilation in Adolescents with Pre-<strong>Hypertension</strong> and<br />

<strong>Hypertension</strong><br />

Sarah C. Couch, 1 Linda Levin, 2 Amanda Thopy, 1 Brian<br />

E. Saelens, 3 Mark Mitsnefes, 4 Stephen R. Daniels, 5<br />

Elaine M. Urbina. 4 1 University <strong>of</strong> Cincinnati Medical<br />

Center, Cincinnati, OH, US; 2 University <strong>of</strong> Cincinnati,<br />

Cincinnati, OH, US; 3 Children’s Hospital and<br />

Regional Medical Center, Seattle, WA, US; 4 Cincinnati<br />

Children’s Hospital Medical Center, Cincinnati, OH,<br />

US; 5 University <strong>of</strong> Colorado School <strong>of</strong> Medicine,<br />

Denver, CO, US.<br />

Determinants <strong>of</strong> Arterial Stiffness in Children and<br />

Adolescents<br />

George S. Stergiou, Anastasios Kollias, Periklis Giovas,<br />

Leonidas Roussias. University <strong>of</strong> Athens, Athens, GR.<br />

Prevalence <strong>of</strong> Overweight and Elevated Blood<br />

Pressure in a Large Cohort <strong>of</strong> Children and<br />

Adolescents (Age 3-17 Years) at an Initial Clinic<br />

Examination<br />

Kenneth F. Adams, 1 Karen L. Margolis, 1 David<br />

J. Magid, 2 Joan C. Lo, 3 Alan R. Sinaiko, 4 Elyse<br />

O. Kharbanda, 1 Nancy E. Sherwood, 1 Matt F.<br />

Daley, 2 Emily D. Parker, 1 Patrick J. O’Connor. 1<br />

1 HealthPartners Research Foundation, Minneapolis,<br />

MN, US; 2 Kaiser Permanente Colorado, Denver, CO,<br />

US; 3 Kaiser Permanente Northern California, Oakland,<br />

CA, US; 4 University <strong>of</strong> MN, Minneapolis, MN, US.<br />

106


Sunday Morning MAY 22<br />

Posters<br />

10:00 AM – 6:30 PM • Second Floor Promenade<br />

Aldosterone and anti-aldosterone<br />

agents<br />

PO-124:<br />

PO-125:<br />

PO-126:<br />

PO-127:<br />

PO-128:<br />

PO-129:<br />

Aldosterone Metrics and Their Ability to<br />

Discriminate between Incident Resistant<br />

<strong>Hypertension</strong> during Follow-Up in a Hypertensive<br />

Cohort<br />

Jennifer D. Dochee, Berhane Seyoum, Phillip Levy,<br />

Brain Ference, Shiling Zhang, Lowell Hedquist, John<br />

Flack. Wayne State University, Detroit, MI, US.<br />

Aldosterone-Induced Rise in Blood Pressure in<br />

Normotensive Rats is Due to a Decrease in PGE 2<br />

Levels<br />

Danita Eatman, Aisha Rollins-Hairston, Deborah Lyn,<br />

Mohamed A. Bayorh. Morehouse School <strong>of</strong> Medicine,<br />

Atlanta, GA, US.<br />

Delayed Diagnosis <strong>of</strong> Primary Aldosteronism-<br />

Help from the Web: A Yahoo Support Group for<br />

Patients Struggling with Diagnosis and Long-Term<br />

Management<br />

Clarence E. Grim. High Blood Pressure Consulting,<br />

Milwaukee, US.<br />

Dose Titration <strong>of</strong> the Oral Potassium Binder-<br />

RLY5016 to Maintain Normal Serum Potassium in<br />

Heart Failure and Chronic Kidney Disease Patients<br />

on Aldosterone Antagonists<br />

Bertram Pitt†, 1 David Bushinsky, 2 Sherin Halfon, 3<br />

Dalane Kitzman, 4 Mitja Lainscak, 5 Vandana Mathur, 3<br />

Yuri Stasiv, 3 I.‐Zu Huang. 3 1 U. <strong>of</strong> Michigan, US; 2 U. <strong>of</strong><br />

Rochester, US; 3 Relypsa, US; 4 Wake Forest U., US; 5 U.<br />

Clinic Golnik, SI.<br />

Hyperkalemia with Aldosterone Antagonist<br />

Monotherapy in Essential <strong>Hypertension</strong>. A Meta-<br />

Analysis<br />

Jorge Romero, 1 Harikrishna Makani, 1 Jonathan<br />

Kahan, 1 Omar Wever‐Pinzon, 2 Clinton Colaco, 1 Franz<br />

H. Messerli. 1 1 St Luke’s Roosevelt Medical Center/<br />

Columbia University College <strong>of</strong> Physicians and<br />

Surgeons, New York, NY, US; 2 The University <strong>of</strong> Utah-<br />

Health Sciences Center, US.<br />

Body Mass Index Correlates with Plasma<br />

Aldosterone in Overweight/Obese Hypertensive<br />

Patients Despite Drug Therapy<br />

Riccardo Sarzani, Federico Guerra, Lucia Mancinelli,<br />

Alessia Buglioni, Eliana Franchi, Paolo Dessì‐Fulgheri.<br />

University Politecnica delle Marche, Ancona, IT.<br />

107


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-130:<br />

Aldosterone to Renin Ratio as a Predictor <strong>of</strong><br />

Mortality and Cardiovascular Outcomes<br />

John J. Sim†, 1 Simran K. Bhandari, 1 Jiaxiao M. Shi, 2<br />

Federico B. Calara, 4 Scott A. Rasgon, 1 Kamyar<br />

Kalantar‐Zadeh. 3 1 Kaiser Permanente Los Angeles<br />

Medical Center, Los Angeles, CA, US; 2 Kaiser<br />

Permanente Southern California, US; 3 Harbor UCLA<br />

Medical Center, US; 4 Novartis Corporation, US.<br />

Antihypertensive Drugs and<br />

Pharmacology<br />

PO-131:<br />

PO-132:<br />

PO-133:<br />

PO-134:<br />

PO-135:<br />

PO-136:<br />

Both Morning and Evening Dosing <strong>of</strong> Nebivolol<br />

Reduces Trough to Morning Blood Pressure Surge in<br />

Hypertensive Patients<br />

Maria Czarina Acelajado, 1 Roberto Pisoni, 3 Tanja<br />

Dudenbostel, 2 David A. Calhoun, 2 Stephen P. Glasser. 2<br />

1 Philippine General Hospital, Manila, PH; 2 University<br />

<strong>of</strong> Alabama at Birmingham, Birmingham, AL, US;<br />

3 Medical University <strong>of</strong> South Carolina, Charleston, SC,<br />

US.<br />

Administration-Time-Dependent Effects on<br />

Ambulatory Blood Pressure <strong>of</strong> Hydrochlorothiazide<br />

as Added Therapy in Hypertensive Subjects<br />

Uncontrolled with Valsartan<br />

Diana E. Ayala, Ramon C. Hermida, Artemio Mojon,<br />

Jose R. Fernandez. University <strong>of</strong> Vigo, Vigo, ES.<br />

Irbesartan/Amlodipine Fixed Combination<br />

in Patients Uncontrolled on Amlodipine 5 mg<br />

(I-COMBINE Study)<br />

Guillaume Bobrie. European George Pompidou<br />

Hospital, Paris, FR.<br />

Irbesartan/Amlodipine Fixed Combination in<br />

Patients Uncontrolled on Irbesartan 150 mg (I-ADD<br />

Study)<br />

Guillaume Bobrie. European George Pompidou<br />

Hospital, Paris, FR.<br />

Poly(3-Hydroxybutyrate) Nanoparticles Loaded with<br />

Paclitaxel Cause Prolonged Antiproliferative Action<br />

Anton P. Bonartsev, 1 Sergey A. Yakovlev, 2 Elena<br />

A. Filatova, 2 Galina M. Soboleva, 1 Tatiana K.<br />

Mahina, 2 Vera L. Myshkina, 2 Garina A. Bonartseva. 2<br />

1 M.V.Lomonosov Moscow State University, Moscow,<br />

RU; 2 Russian Academy <strong>of</strong> Sciences, Moscow, RU.<br />

The Efficacy and Safety <strong>of</strong> Angiotensin Receptor<br />

Blocker and Calcium Channel Blocker Combination<br />

in <strong>Hypertension</strong><br />

Bulent Boyaci, 1 Mehmet Berktas, 2 Pinar Kizilirmak. 2<br />

1 Gazi University Faculty <strong>of</strong> Medicine, Ankara, TR;<br />

2 Novartis Pharma, Istanbul, TR.<br />

108


Sunday Morning MAY 22<br />

Posters<br />

PO-137:<br />

PO-138:<br />

PO-139:<br />

PO-140:<br />

PO-141:<br />

Better Control <strong>of</strong> Central Pressures and Total<br />

Hypertensive Time in Patients with <strong>Hypertension</strong><br />

Receiving Telmisartan as Monotheraphy. Prospective<br />

Study<br />

Ricardo M. Cabrera Sole, 1 Caridad Turpin Lucas, 1<br />

Santiago Garcia Ruiz, 1 Rafael Fernandez, 2 Erik<br />

Luepke. 3 1 University General Hospital <strong>of</strong> Albacete,<br />

Albacete, ES; 2 Health Center <strong>of</strong> Villarrobledo,<br />

Albacete, ES; 3 University General Hospital “La Paz”,<br />

Madrid, ES.<br />

Intravenous Hydralazine for Blood Pressure<br />

Management in the Hospitalized Patient<br />

Patrick T. Campbell, William L. Baker, Bendel D.<br />

Steven, William B. White. University <strong>of</strong> Connecticut<br />

School <strong>of</strong> Medicine, Farmington, CT, US.<br />

Long-Term Efficacy and Safety <strong>of</strong> Combination<br />

Olmesartan Medoxomil/Amlodipine<br />

Besylate+Hydrochlorothiazide in Study Participants<br />

with <strong>Hypertension</strong> Based on Age: The TRINITY<br />

Study<br />

Steven G. Chrysant†, 1 Dean J. Kereiakes, 2 Suzanne<br />

Oparil, 3 Joseph Izzo, 4 Thomas Littlejohn, 5 Michael<br />

Melino, 6 James Lee, 6 Victor Fernandez, 6 Reinilde<br />

Heyrman. 6 1 Oklahoma Cardiovascular and<br />

<strong>Hypertension</strong> Center and University <strong>of</strong> Oklahoma<br />

College <strong>of</strong> Medicine, US; 2 The Christ Hospital Heart<br />

and Vascular Center and The Carl and Edyth Lindner<br />

Center for Research and Education at the Christ<br />

Hospital, US; 3 University <strong>of</strong> Alabama at Birmingham,<br />

US; 4 State University <strong>of</strong> New York at Buffalo, US;<br />

5 Piedmont Medical Research Associates, US; 6 Daiichi<br />

Sankyo, Inc, US.<br />

Long-Term Efficacy and Safety <strong>of</strong> Combination<br />

Olmesartan Medoxomil/Amlodipine<br />

Besylate+Hydrochlorothiazide—The TRINITY<br />

Study: A Subgroup Analysis by Study Participant<br />

Race<br />

Steven G. Chrysant†, 1 Dean J. Kereiakes, 2 Joseph Izzo, 3<br />

Thomas Littlejohn, 4 Suzanne Oparil, 5 Michael Melino, 6<br />

James Lee, 6 Victor Fernandez, 6 Reinilde Heyrman. 6<br />

1 Oklahoma Cardiovascular and <strong>Hypertension</strong> Center<br />

and University <strong>of</strong> Oklahoma College <strong>of</strong> Medicine, US;<br />

2 The Christ Hospital Heart and Vascular Center and<br />

The Carl and Edyth Lindner Center for Research and<br />

Education at the Christ Hospital, US; 3 State University<br />

<strong>of</strong> New York at Buffalo, US; 4 Piedmont Medical<br />

Research Associates, US; 5 University <strong>of</strong> Alabama at<br />

Birmingham, US; 6 Daiichi Sankyo, Inc, US.<br />

Comparison <strong>of</strong> Valsartan/Amlodipine Added to<br />

Diuretic with Losartan Added to Diuretic on BP<br />

Load in <strong>Hypertension</strong><br />

Daniel Duprez†, 1 Keith Ferdinand, 2 Das Purkayastha, 3<br />

Rita Samuel, 3 Richard F. Wright. 4 1 University <strong>of</strong><br />

Minnesota, Minneapolis, MN, US; 2 Emory University,<br />

Atlanta, GA, US; 3 Novartis Pharmaceuticals<br />

Corporation, East Hanover, NJ, US; 4 Pacific Heart<br />

Insitute, Santa Monica, CA, US.<br />

109


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-142:<br />

PO-143:<br />

PO-144:<br />

PO-145:<br />

PO-146:<br />

PO-147:<br />

PO-148:<br />

The Impact <strong>of</strong> Initial Treatment <strong>of</strong> <strong>Hypertension</strong><br />

on Control in the First Year: Comparison <strong>of</strong> Initial<br />

Monotherapy, Free-Dose Combination and Fixed-<br />

Dose Combinations<br />

Brent Egan†, 1 Stephanie Shaftman, 1 Dipankar<br />

Bandyopadhyay, 1 C. Wagner, 1 Daniel Lackland, 1<br />

Kristina Yu‐Isenberg. 2 1 Medical University <strong>of</strong> South<br />

Carolina, SC, US; 2 Novartis Pharmaceuticals, NJ, US.<br />

A Bedtime Dose <strong>of</strong> ARB Reduces Urinary Albumin<br />

Excretion Via the Improvement <strong>of</strong> Baroreflex<br />

Sensitivity – The J-TOP Study<br />

Kazuo Eguchi, Motohiro Shimizu, Satoshi Hoshide,<br />

Kazuyuki Shimada, Shizukiyo Ishikawa, Kazuomi<br />

Kario. Jichi Medical University School <strong>of</strong> Medicine,<br />

Shimotsuke, Tochigi-ken, JP.<br />

Response to Aliskiren in Patients with Non-<br />

Controlled Blood Pressure Seems to be Irrespective<br />

<strong>of</strong> Previous Therapy and Plasma Renin Activity<br />

Angelica Fernandez, Susana Tello, Asuncion Guerri,<br />

Olivia Sanchez, Rosa Fabregate, Martin Fabregate,<br />

Arantxa Rodriguez, Jose Saban‐Ruiz. Ramon y Cajal<br />

Hospital, Madrid, ES.<br />

Impact <strong>of</strong> Initial Combination Therapy vs.<br />

Monotherapy on Major Cardiovascular Events: A<br />

Matched Cohort Study<br />

Alan H. Gradman†, 1 Hélène Parisé, 2 Marie‐Hélène<br />

Lafeuille, 2 Heather Falvey, 3 Patrick Lefebvre, 2 Mei<br />

Sheng Duh. 2 1 Temple University School <strong>of</strong> Medicine<br />

(Clinical Campus), Pittsburgh, PA, US; 2 Analysis<br />

Group, Inc., Boston, MA, US; 3 Novartis Pharma AG,<br />

Basel, CH.<br />

Relationship between Sleep-Time Blood Pressure<br />

Control and Reduction <strong>of</strong> Urinary Albumin<br />

Excretion after Timed-Treatment with Olmesartan<br />

in Essential <strong>Hypertension</strong><br />

Ramon C. Hermida, Diana E. Ayala, Maria J. Fontao,<br />

Artemio Mojon, Jose R. Fernandez. University <strong>of</strong> Vigo,<br />

Vigo, ES.<br />

Nebivolol and Hydrochlorothiazide in African-<br />

<strong>American</strong>s with <strong>Hypertension</strong>: Effects on Diastolic<br />

and Endothelial Function<br />

Bobby V. Khan†, Nadya Merchant, Tahir Haque, Syed<br />

T. Rahman, Sujan Bhaheetharan, Keith C. Ferdinand.<br />

Emory University School <strong>of</strong> Medicine, Atlanta, GA,<br />

US.<br />

Peripheral Edema Associated with Calcium<br />

Antagonists<br />

Harikrishna Makani, Jorge Romero, Nay Htyte,<br />

Ronaldo Sevilla Berrios, Arpit Shah, Waddy Gonzalez,<br />

Franz H. Messerli. St. Luke’s Roosevelt Hospital<br />

and Columbia University College <strong>of</strong> Physicians and<br />

Surgeons, New York, NY, US.<br />

110


Sunday Morning MAY 22<br />

Posters<br />

PO-149:<br />

PO-150:<br />

PO-152:<br />

PO-153:<br />

PO-154:<br />

PO-155:<br />

Efficacy <strong>of</strong> a Simplified Mechanistic Algorithm<br />

for Management <strong>of</strong> Resistant <strong>Hypertension</strong>: A<br />

Retrospective Study<br />

Neal S. Parikh, Samuel J. Mann†. NY Presbyterian<br />

Hospital – Weill Cornell Med Ctr, New York, NY, US.<br />

Long-Term Efficacy and Safety <strong>of</strong> Combination<br />

Olmesartan Medoxomil/Amlodipine<br />

Besylate+Hydrochlorothiazide—The TRINITY<br />

Study: Subgroup Analyses Based on Study<br />

Participant Diabetes Status and BMI<br />

Suzanne Oparil†, 1 Joseph Izzo, 2 Steven G. Chrysant, 3<br />

Dean J. Kereiakes, 4 Thomas Littlejohn, 5 Michael<br />

Melino, 6 James Lee, 6 Victor Fernandez, 6 Reinilde<br />

Heyrman. 6 1 University <strong>of</strong> Alabama at Birmingham,<br />

US; 2 State University <strong>of</strong> New York at Buffalo, US;<br />

3 Oklahoma Cardiovascular and <strong>Hypertension</strong> Center<br />

& University <strong>of</strong> Oklahoma College <strong>of</strong> Medicine, US;<br />

4 The Christ Hospital Heart and Vascular Center &<br />

The Carl and Edyth Lindner Center for Research<br />

and Education, US; 5 Piedmont Medical Research<br />

Associates, US; 6 Daiichi Sankyo, Inc, US.<br />

Differential Cardioprotective Effects <strong>of</strong> Carvedilol<br />

and Valsartan under Different Cardiac Loading<br />

Conditions<br />

Minesh Rajpal†, Shaila Karan, Sirisha Srikakarlapudi,<br />

Peter J. Osmond, Joseph L. Izzo. SUNY at Buffalo, NY,<br />

US.<br />

Effects <strong>of</strong> Time <strong>of</strong> <strong>Hypertension</strong> Treatment on the<br />

Circadian Blood Pressure Pattern <strong>of</strong> Subjects with<br />

Resistant <strong>Hypertension</strong>: The Hygia Project<br />

Maria T. Rios, 1 Manuel Dominguez‐Sardiña, 1 Lorenzo<br />

Pousa, 1 Jesus Perez de Lis, 1 Alfonso Otero, 2 Maria<br />

J. Fontao, 3 Jose R. Fernandez, 3 Diana E. Ayala, 3<br />

Ramon C. Hermida, 3 Investigadores Proyecto Hygia. 3<br />

1 Gerencia de Atención Primaria, Vigo, ES; 2 Complejo<br />

Hospitalario Universitario, Orense, ES; 3 University <strong>of</strong><br />

Vigo, Vigo, ES.<br />

Plasma Renin-Guided Treatment in Young<br />

Untreated <strong>Hypertension</strong>: A Randomized<br />

Comparative Pilot Study<br />

Il‐Suk Sohn, 1 Chang‐Bum Park, 1 Eun‐Sun Jin, 1<br />

Chong‐Jin Kim, 1 Jin‐Man Cho. 2 1 Kyung Hee<br />

University Gangdong Hospital, Seoul, KR; 2 Aab<br />

Cardiovascular Research Institute, Rochester, NY, US.<br />

Angiotensin Converting Enzyme Inhibitors or<br />

Angiotensin Receptor Blockers as First-Line<br />

Treatment in Patients with Uncomplicated<br />

<strong>Hypertension</strong><br />

Konstantinos Tziomalos, Maria Baltatzi, Athinodoros<br />

Pavlidis, Konstantinos Koulousios, Vasiliki Dourliou,<br />

Anastasios Hatzopoulos, Vaia Bougatsa, Lambrini<br />

Kirkineska, Christos Savopoulos, Apostolos I.<br />

Hatzitolios. Medical School, Aristotle University <strong>of</strong><br />

Thessaloniki, AHEPA Hospital, Thessaloniki, GR.<br />

111


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-156:<br />

PO-157:<br />

Amlodipine/Valsartan Single Pill Combination<br />

Treatment <strong>of</strong> Arterial <strong>Hypertension</strong> in a Real Life<br />

Practice in Russia<br />

Irina E. Chazova, 1 Yuri A. Karpov, 1 Alexey V.<br />

Vigdorchik†, 2 Antonina Y. Zazulina. 2 1 Russian<br />

Cardiology Scientific-Industrial Complex, Moscow,<br />

RU; 2 Novartis Pharma LLC, Moscow, RU.<br />

Real Life Safety and Effectiveness <strong>of</strong> Amlodipine/<br />

Valsartan Single Pill Combination in the Treatment<br />

<strong>of</strong> <strong>Hypertension</strong><br />

Irina E. Chazova, 1 Neelesh Dongre, 2 Alexey V.<br />

Vigdorchik†. 3 1 Russian Cardiology Scientific-Industrial<br />

Complex, Moscow, RU; 2 Novartis Pharma AG, Basel,<br />

CH; 3 Novartis Pharma LLC, Moscow, RU.<br />

Clinical Trials<br />

PO-158:<br />

PO-159:<br />

PO-160:<br />

PO-161:<br />

PO-162:<br />

The Influence <strong>of</strong> Antihypertensive Therapy on Blood<br />

Pressure Variability: The X-CELLENT Study<br />

Yi Zhang, 1,2 Davide Agnoletti, 1 Michel E. Safar, 1<br />

Jacques Blacher. 1 1 Paris Descartes University, Paris,<br />

FR; 2 Jiaotong University School <strong>of</strong> Medicine, Shanghai,<br />

CN.<br />

A Double-Dummy Comparison <strong>of</strong> De Novo<br />

Combination vs Sequential Add-On Therapy:<br />

‘ACCELERATE’<br />

Morris Brown, 1,2 Gordon McInnes, 1,3 Cheraz Cherif<br />

Papst, 4 Jack Zhang, 4 Thomas MacDonald. 1,5 1 British<br />

<strong>Hypertension</strong> <strong>Society</strong>, GB; 2 University <strong>of</strong> Cambridge,<br />

GB; 3 University <strong>of</strong> Glasgow, GB; 4 Novartis Pharma<br />

AG, CH; 5 University <strong>of</strong> Dundee, GB.<br />

Amlodipine Plus Telmisartan or Amiloride for<br />

Hypertensive Patients: Focus on Effects on Metabolic<br />

Pr<strong>of</strong>iles<br />

Hong Yuan, Jingjing Cai, Zhijun Huang. The Center <strong>of</strong><br />

Clinical Pharmacology <strong>of</strong> the Third Xiangya Hospital,<br />

Central South University, Changsha, CN.<br />

Amlodipine Plus Telmisartan or Amiloride for<br />

<strong>Hypertension</strong> in Moderate and High-Risk Patients:<br />

A 24-Week Observation<br />

Jingjing Cai, Zhijun Huang, Rong Cui, Hong Yuan. The<br />

Center <strong>of</strong> Clinical Pharmacology <strong>of</strong> the Third Xiangya<br />

Hospital, Central South University, Changsha, CN.<br />

Efficacy and Safety <strong>of</strong> Azilsartan Medoxomil/<br />

Chlorthalidone vs Olmesartan/HCTZ Combinations<br />

in Stage 2 Systolic HTN<br />

William C. Cushman†, 1 Domenic Sica, 2 George L.<br />

Bakris, 3 Michael A. Weber, 4 William B. White, 5<br />

Charlie Cao, 6 Andrew Roberts, 6 Stuart Kupfer. 6 1 U<br />

<strong>of</strong> TN College <strong>of</strong> Medicine, Memphis, TN, US; 2 VA<br />

Commonwealth U Health System, Richmond, VA,<br />

US; 3 U <strong>of</strong> Chicago Pritzker School <strong>of</strong> Medicine,<br />

Chicago, IL, US; 4 New York, NY, US; 5 U <strong>of</strong> CT School<br />

<strong>of</strong> Medicine, Farmington, CT, US; 6 Takeda Global<br />

Research & Development, Deerfield, IL, US.<br />

112


Sunday Morning MAY 22<br />

Posters<br />

PO-163: Effect <strong>of</strong> Aliskiren and Antihypertensive Drugs on<br />

Diastolic Function in Hypertensives with Diastolic<br />

Dysfunction: A Randomised Study<br />

Maria Leonarda De Rosa. University <strong>of</strong> Naples<br />

Federico II, Naples, IT.<br />

PO-164: Effects <strong>of</strong> Add-On Nebivolol on Blood Pressure and<br />

Glucose Parameters in Hypertensive Patients with<br />

Prediabetes<br />

P. Deedwania†, 1 D. G. Cheung, 2 J. Shea, 3 W. Chen, 3 J. J.<br />

Whalen. 3 1 UCSF, US; 2 Long Beach Center for Clinical<br />

Research, US; 3 Forest Research Institute, US.<br />

PO-165: Incident Diabetes with Antihypertensive Drugs:<br />

Updated Network and Bayesian Meta-Analyses <strong>of</strong><br />

Clinical Trial Data<br />

William J. Elliott†, 1 Sanjib Basu, 2 Peter M. Meyer. 2<br />

1 Pacific Northwest University <strong>of</strong> Health Sciences,<br />

Yakima, WA, US; 2 RUSH Medical College, Chicago,<br />

IL, US.<br />

PO-166: Efficacy and Safety <strong>of</strong> Combination DRI/CCB (±<br />

Diuretic) in US Minority Patients with Stage 2<br />

<strong>Hypertension</strong> and Obesity<br />

Keith C. Ferdinand†, 1 Richard Weitzman, 2 Das<br />

Purkayastha, 2 Kanaka Sridharan, 2 Edgar A. Jaimes. 3<br />

1 Emory University, Atlanta, GA, US; 2 Novartis<br />

Pharmaceuticals Corporation, East Hanover, NJ,<br />

US; 3 The University <strong>of</strong> Alabama at Birmingham,<br />

Birmingham, AL, US.<br />

PO-167: Efficacy <strong>of</strong> Combination Aliskiren/Amlodipine with<br />

and without Diuretic on Ambulatory Blood Pressure<br />

in Minorities with <strong>Hypertension</strong><br />

Keith C. Ferdinand†, 1 Richard Weitzman, 2 Das<br />

Purkayastha, 2 Kanaka Sridharan, 2 Edgar A. Jaimes. 3<br />

1 Emory University, Atlanta, GA, US; 2 Novartis<br />

Pharmaceuticals Corp, East Hanover, NJ, US; 3 The<br />

University <strong>of</strong> Alabama at Birmingham, Birmingham,<br />

AL, US.<br />

PO-168: Role <strong>of</strong> Plasma Renin Activity on BP Response to<br />

Aliskiren-Based Therapy in Stage 2 Hypertensive<br />

African <strong>American</strong>s<br />

Keith C. Ferdinand†, 1 Richard Weitzman, 2 Das<br />

Purkayastha, 2 Kanaka Sridharan, 2 Edgar A. Jaimes. 3<br />

1 Emory University, Atlanta, GA, US; 2 Novartis<br />

Pharmaceuticals Corporation, East Hanover, NJ,<br />

US; 3 The University <strong>of</strong> Alabama at Birmingham,<br />

Birmingham, AL, US.<br />

PO-169: Efficacy and Safety <strong>of</strong> Combination DRI/CCB<br />

(±Diuretic) Therapy in African <strong>American</strong>s with<br />

Stage 2 <strong>Hypertension</strong><br />

Keith C. Ferdinand†, 1 Richard Weitzman, 2 Das<br />

Purkayastha, 2 Kanaka Sridharan, 2 Edgar A. Jaimes. 3<br />

1 Emory University, Atlanta, GA, US; 2 Novartis<br />

Pharmaceuticals Corporation, East Hanover, NJ,<br />

US; 3 The University <strong>of</strong> Alabama at Birmingham,<br />

Birmingham, AL, US.<br />

113


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-170:<br />

PO-171:<br />

PO-172:<br />

PO-173:<br />

PO-174:<br />

PO-175:<br />

PO-176:<br />

PO-177:<br />

PO-178:<br />

Combination Aliskiren/Amlodipine with and<br />

without Diuretic in Minorities with <strong>Hypertension</strong><br />

and Metabolic Syndrome or Diabetes<br />

Keith C. Ferdinand†, 1 Richard Weitzman, 2 Das<br />

Purkayastha, 2 Kanaka Sridharan, 2 Edgar A. Jaimes. 3<br />

1 Emory University, Atlanta, GA, US; 2 Novartis<br />

Pharmaceuticals Corp, East Hanover, NJ, US; 3 Univ <strong>of</strong><br />

Alabama at Birmingham, Birmingham, AL, US.<br />

Efficacy and Safety <strong>of</strong> Olmesartan Medoxomil<br />

Versus Losartan Potassium in Subjects with Stage 1<br />

or 2 <strong>Hypertension</strong><br />

John M. Flack†, 1 Alan Graff, 2 Wei Li, 3 Kathleen J.<br />

Chavanu, 3 Robert Dubiel. 3 1 Wayne State University<br />

School <strong>of</strong> Medicine, US; 2 Private Practice, US; 3 Daiichi<br />

Sankyo, Inc., US.<br />

Decreasing Sleep-Time Blood Pressure Determined<br />

by Ambulatory Monitoring Reduces Cardiovascular<br />

Risk in Resistant <strong>Hypertension</strong><br />

Ramon C. Hermida, 1 Diana E. Ayala, 1 Artemio<br />

Mojon, 1 Luisa Chayan, 2 Maria J. Dominguez, 3 Maria<br />

J. Fontao, 1 Ignacio Alonso, 1 Jose R. Fernandez. 1<br />

1 University <strong>of</strong> Vigo, Vigo, ES; 2 Urgencias Sanitarias<br />

061 Galicia, Santiago, ES; 3 Policlinica La Rosaleda,<br />

Santiago, ES.<br />

Influence <strong>of</strong> Circadian Time <strong>of</strong> Blood Pressure-<br />

Lowering Treatment on Cardiovascular Risk in<br />

Resistant <strong>Hypertension</strong><br />

Ramon C. Hermida, Diana E. Ayala, Artemio Mojon,<br />

Jose R. Fernandez. University <strong>of</strong> Vigo, Vigo, ES.<br />

Administration-Time Differential Benefit on<br />

Cardiovascular Risk Reduction <strong>of</strong> the Various<br />

Classes <strong>of</strong> <strong>Hypertension</strong> Medications<br />

Ramon C. Hermida, Diana E. Ayala, Artemio Mojon,<br />

Jose R. Fernandez. University <strong>of</strong> Vigo, Vigo, ES.<br />

Influence <strong>of</strong> Number <strong>of</strong> <strong>Hypertension</strong> Medications<br />

and Circadian Time <strong>of</strong> Treatment on Cardiovascular<br />

Morbidity and Mortality<br />

Ramon C. Hermida, Diana E. Ayala, Artemio Mojon,<br />

Jose R. Fernandez. University <strong>of</strong> Vigo, Vigo, ES.<br />

Doppler Measurement <strong>of</strong> Ankle Brachial Index is<br />

Still the Standard in Screening <strong>of</strong> Peripheral Arterial<br />

Disease<br />

Laura Rantamaula, Juha Varis, Ilkka M. Kantola. Turku<br />

University Hospital, Turku, FI.<br />

Comparative Effects <strong>of</strong> Carvedilol and Valsartan on<br />

Cardiac Workload<br />

Shaila Karan†, Sirisha Srikakarlapudi, Minesh Rajpal,<br />

Peter J. Osmond, Joseph L. Izzo, Jr. SUNY at Buffalo,<br />

Buffalo, NY, US.<br />

Olmesartan + CCB vs Olmesartan + Diuretic as<br />

Combination Therapy for Elderly Hypertensive<br />

Patients<br />

Johji Kato, Naoto Yokota, Toshihiro Kita, Tanenao Eto,<br />

Kazuo Kitamura. University <strong>of</strong> Miyazaki, Miyazaki<br />

City, Miyazaki, JP.<br />

114


Sunday Morning MAY 22<br />

Posters<br />

PO-179:<br />

PO-180:<br />

PO-181:<br />

PO-182:<br />

PO-183:<br />

PO-184:<br />

Efficacy and Safety <strong>of</strong> Olmesartan Medoxomil<br />

Versus Losartan Potassium in Antihypertensive<br />

Naïve/Non-Naïve Subjects<br />

Henry A. Punzi†, 1 Andrew Lewin, 2 Wei Li, 3 Kathleen J.<br />

Chavanu, 3 Robert Dubiel. 3 1 Trinity <strong>Hypertension</strong> and<br />

Metabolic Research Institute, US; 2 National Research<br />

Institute, US; 3 Daiichi Sankyo, Inc., US.<br />

Computer-Mediated System, WHEELS-I, Provides<br />

Evidence <strong>of</strong> Feasibility for Momentary Assessment<br />

<strong>of</strong> D<strong>ASH</strong> Diet Adherence over 8 Weeks<br />

Margaret Scisney‐Matlock, 1 Susan Steigerwalt, 2<br />

Kenneth Jamerson, 1 Amanda Sen, 1 Susan Pressler, 1<br />

Elizabeth Brough. 1 1 University <strong>of</strong> Michigan, Ann<br />

Arbor, MI, US; 2 St. John Health System, Detroit, US.<br />

Carvedilol Reduces Aortic Wave Reflection and<br />

Improves Left Ventricular/Vascular Coupling<br />

Compared to Atenolol: The CENTRAL Study<br />

Niren K. Shah†, 1 Benjamin J. Epstein, 1,2 Wilmer W.<br />

Nichols, 2 Steven M. Smith, 2 Julie A. Johnson. 2 1 East<br />

Coast Institute for Research, Jacksonville, FL, US;<br />

2 University <strong>of</strong> Florida, Gainesville, FL, US.<br />

Fixed-Dose Combination <strong>of</strong> Azilsartan Medoxomil/<br />

CLD Provides Superior BP Reduction to<br />

Monotherapies in Stage 2 HTN<br />

D. Sica†, 1 G. L. Bakris, 2 W. B. White, 3 M. A. Weber, 4<br />

W. C. Cushman, 5 A. Roberts, 6 C. Cao, 6 S. Kupfer. 6 1 VA<br />

Commonwealth U Health System, Richmond, VA, US;<br />

2 U <strong>of</strong> Chicago Pritzker School <strong>of</strong> Medicine, Chicago,<br />

IL, US; 3 U <strong>of</strong> CT School <strong>of</strong> Medicine, Farmington,<br />

CT, US; 4 New York, NY, US; 5 U <strong>of</strong> TN College <strong>of</strong><br />

Medicine, Memphis, TN, US; 6 Takeda Global Research<br />

& Development, Deerfield, IL, US.<br />

Efficacy <strong>of</strong> an Amlodipine/Olmesartan Medoxomil<br />

Algorithm in Patients Uncontrolled on Prior ACE<br />

Inhibitor Monotherapy<br />

Matthew R. Weir†, 1 Alan Graff, 2 Ali Shojaee, 3 William<br />

F. Waverczak, 3 Jen‐Fue Maa. 3 1 University <strong>of</strong> Maryland<br />

School <strong>of</strong> Medicine, US; 2 Private Practice, US; 3 Daiichi<br />

Sankyo, Inc., US.<br />

Pilot Randomized Controlled Trial <strong>of</strong> Intensive<br />

Blood Pressure Control in Hemodialysis Dialysis<br />

Patients: The BID Trial<br />

Philip Zager, 1 Dana Miskulin, 2 Jennifer Gassman. 3<br />

1 University <strong>of</strong> New Mexico Health Sciences Center,<br />

Albuquerque, NM, US; 2 Tufts Medical Center, Boston,<br />

MA, US; 3 Cleveland Clinic Research Foundation,<br />

Cleveland, OH, US.<br />

Coronary Artery Disease<br />

PO-185:<br />

Blood Pressure and Heart Related Quality <strong>of</strong> Life<br />

One Year Post Myocardial Infarction<br />

Antonios Ioannidis, Dimitrios Tsounis. Hellenic Open<br />

University, GR.<br />

115


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-186:<br />

PO-187:<br />

PO-188:<br />

PO-189:<br />

PO-190:<br />

PO-191:<br />

False-Positive Stress Testing Results in<br />

Hypertensives with No Coronary Artery Disease<br />

Fei Lu, 1 Gabriele Fragasso, 2 Chunzeng Lu, 1 Vitantonio<br />

Di Bello, 1 Roberto Pedrinelli, 1 Mario Marzilli, 1 Alberto<br />

Balbarini. 1 1 University <strong>of</strong> Pisa, IT; 2 Scientific Institute<br />

<strong>of</strong> H San Raffaele, IT.<br />

Inadequate Blood Pressure Control in Hypertensives<br />

Referred for Cardiac Stress Testing<br />

Tarek M. Mousa, Harmony Leighton, Seema Patel,<br />

Todd Kerwin. New York Hospital Medical Center <strong>of</strong><br />

Queens/Cornell University Weill Medical College,<br />

Flushing, NY, US.<br />

Relationship between Exercise Intolerance and<br />

Plasma Natriuretic Peptide Level in Hypertensives<br />

with Postinfarction Cardiosclerosis<br />

Mariya A. Orynchak, Iryna I. Vakalyuk, Igor P.<br />

Vakalyuk. Ivano-Frankivsk National Medical<br />

University, Ivano-Frankivsk, UA.<br />

Influence <strong>of</strong> a History <strong>of</strong> <strong>Hypertension</strong> with Clinical<br />

Presentation and Prognosis after Admission<br />

with Non ST Segment Elevation Acute Coronary<br />

Syndrome<br />

Joaquin Rueda Soriano, Miguel Angel Arnau Vives,<br />

Ana Osa Saez, Esther Zorio Grima, Luis Martínez<br />

Dolz, Luis Almenar, Miguel Palencia Pérez, Antonio<br />

Salvador Sanz. Hospital La Fe, Valencia, ES.<br />

Characteristics <strong>of</strong> Hypertensive Response during<br />

Exercise Echocardiography in Hypertensive Patients<br />

with No History <strong>of</strong> Coronary Artery Disease<br />

Il‐Suk Sohn, Chang‐Bum Park, Eun‐Sun Jin, Jin‐Man<br />

Cho, Chong‐Jin Kim, Jong‐Hoa Bae. Kyung Hee<br />

University School <strong>of</strong> Medicine, Seoul, KR.<br />

The Ankle-Brachial Index as a Predictor <strong>of</strong> Coronary<br />

Artery Disease<br />

Svetlana Kostic, Dragan Mijalkovic, Ivan Tasic.<br />

Institute for Therapy and Rehabilitation “Niska Banja”,<br />

Niska Banja, RS.<br />

Genetics/Gene Therapy/Proteomics<br />

PO-192:<br />

PO-193:<br />

Cardiac BNP Gene Delivery Prevents Hypertensive<br />

Heart Disease in Spontaneous Hypertensive Rats<br />

Alessandro Cataliotti, 1 Fernando L. Martin, 1 Jason M.<br />

Tonne, 2 Diego Bellavia, 1 John C. Burnett, 1 Yasuhiro<br />

Ikeda. 2 1 Mayo Clinic, Rochester, MN, US; 2 Mayo<br />

Clinic, Rochester, MN, US.<br />

DNA Variants in NOS3 are Associated with<br />

Improved Small Artery Elasticity and Decreased<br />

Systolic Blood Pressure<br />

Daniel Duprez, 1 Natalia Florea, 1 Sara Saul, 1 Ryan<br />

Palaciao, 1 Steven Rich, 2 Jay N. Cohn, 1 Jennifer Hall. 1<br />

1 University <strong>of</strong> Minnesota, Minneapolis, MN, US;<br />

2 University <strong>of</strong> Virginia, Charlottesville, VA, US.<br />

116


Sunday Morning MAY 22<br />

Posters<br />

PO-194:<br />

PO-195:<br />

PO-196:<br />

PO-198:<br />

SNP-SNP Interactions among <strong>Hypertension</strong> Related<br />

Genes<br />

Masahiko Eto, 1 Takanori Aonuma, 1 Masanobu<br />

Okayama, 2 Maki Kumada, 2 Ritei Uehara, 2 Yoshikazu<br />

Nakamura, 2 Eiji Kajii. 2 1 Wakuya Medical and Welfare<br />

Center, Wakuya, Miyagi, JP; 2 Jichi Medical University,<br />

Shimotsuke, Tochigi, JP.<br />

Blood Pressure, Endothelial Dysfunction, Lipid<br />

Pr<strong>of</strong>ile and CYP3A5 Gene Polymorphism in Uzbek<br />

Hypertensive Patients<br />

Amayak Kevorkov, Marietta Eliseyeva. Republican<br />

Specialized Center <strong>of</strong> Cardiology, Tashkent, UZ.<br />

Mitochondrial Polymorphisms are Associated<br />

with Blood Pressure and Metabolic Traits in the<br />

Framingham Heart Study<br />

Chunyu Liu, 1,2 Qiong Yang, 3 Shih‐Jen Hwang, 1,2<br />

Fengzhu Sun, 4 Caroline S. Fox, 1 Ramachandran S.<br />

Vasan, 1,5 Faina Schwartz, 5 Daniel Levy. 1,2 1 National<br />

Heart, Lung, and Blood Institute’s Framingham Heart<br />

Study, Framingham, MA, US; 2 NHLBI, Bethesda,<br />

MD, US; 3 Boston University School <strong>of</strong> Public Health,<br />

Boston, MA, US; 4 University <strong>of</strong> Southern California,<br />

Los Angeles, CA, US; 5 Boston University School <strong>of</strong><br />

Medicine, Boston, MA, US.<br />

Targeted Disruption <strong>of</strong> Npr1 Gene Upregulates<br />

Renin-Angiotensin System and Cardiac<br />

Hypertrophy in Null Mutant Mice<br />

Kailash N. Pandey. Tulane University Health Sciences<br />

School <strong>of</strong> Medicine, New Orleans, LA, US.<br />

Heart Failure/Hypertrophy (Diastolic<br />

Dysfunction)<br />

PO-199:<br />

PO-200:<br />

PO-201:<br />

A Meta-Analysis <strong>of</strong> the Effect <strong>of</strong> Anti-Hypertensive<br />

Treatment on Echocardiogram Parameters in Heart<br />

Failure Patients with Preserved Ejection Fraction<br />

Alex Briasoulis, 1 Vikram Agarwal, 1 Manpreet S.<br />

Sabharwal, 1 Girish N. Nadkarni, 1 Franz H. Messerli. 2<br />

1 St. Luke’s-Roosevelt Hospital Center, Columbia<br />

University College <strong>of</strong> Physicians and Surgeons, New<br />

York, NY, US; 2 St. Luke’s-Roosevelt Hospital Center,<br />

Columbia University College <strong>of</strong> Physicians and<br />

Surgeons, New York, NY, US.<br />

Effects <strong>of</strong> Renin-Angiotensin System Blockade on<br />

Mortality and Rehospitalization in Heart Failure<br />

with Preserved Ejection Fraction<br />

Vikram V. Agarwal, 1 Alexandros Briasoulis, 1 Girish<br />

Nadkarni, 1 Manpreet S. Sabharwal, 1 Nidhi Hans, 2<br />

Franz H. Messerli. 1 1 St. Luke’s-Roosevelt Hospital<br />

Center, New York, NY, US; 2 Harvard School <strong>of</strong> Public<br />

Health, Boston, MA, US.<br />

Socioeconomic Status and Costs in Heart Failure<br />

Billy G. Chacko, Tej K. Atluri, Syed U. Naqvi, Hamza<br />

Rana, Pavel J. Levy, Kimberley J. Hansen. Wake Forest<br />

University Baptist Medical Center, Winston Salem,<br />

NC, US.<br />

117


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-202: Can High Dose <strong>of</strong> Valsartan Improve Ventricular-<br />

Vascular Coupling in Heart Failure<br />

Wook‐Jin Chung†, 1 Hye‐Sun Seo, 2 Sung‐Hee Shin, 3<br />

Young‐Sup Byun, 4 Sung‐Kee Ryu, 5 Wook‐Bum Pyun, 6<br />

Se‐Joong Rim. 7 1 Gachon University Gil Hospital,<br />

Gachon University School <strong>of</strong> Medicine, Incheon,<br />

KR; 2 Inha University Hospital, KR; 3 Soonchunhyang<br />

University School <strong>of</strong> Medicine, KR; 4 Sanggye Paik<br />

Hospital, Inje University College <strong>of</strong> Medicine, KR;<br />

5 Eulji General Hospital, Eulji University School <strong>of</strong><br />

Medicine, KR; 6 Ewha Womans University, School <strong>of</strong><br />

Medicine, KR; 7 Gangnam Severance Hospital, Yonsei<br />

University College <strong>of</strong> Medicine, KR.<br />

PO-203: Can N-Terminal pro-B Type Natriuretic Peptide<br />

Predict LV Diastolic Dysfunction in Hypertensive<br />

Heart Disease<br />

Wook‐Jin Chung, 1 Sung‐Hee Shin, 2 Hye‐Sun Seo, 3<br />

Young‐Sup Byun, 4 Sung‐Kee Ryu, 5 Wook‐Bum<br />

Pyun, 6 Se‐Joong Rim. 7 1 Gachon University Gil<br />

Hospital, Gachon University School <strong>of</strong> Medicine,<br />

Incheon, KR; 2 Inha University Hospital, Incheon,<br />

KR; 3 Soonchunhyang University School <strong>of</strong> Medicine,<br />

Bucheon, KR; 4 Sanggye Paik Hospital, Inje University<br />

College <strong>of</strong> Medicine, KR; 5 Eulji General Hospital, Eulji<br />

University School <strong>of</strong> Medicine, KR; 6 Ewha Womans<br />

University, School <strong>of</strong> Medicine, KR; 7 Gangnam<br />

Severance Hospital, Yonsei University College <strong>of</strong><br />

Medicine, KR.<br />

PO-204: PPARg Agonist Inhibits, and PPARg Antagonist<br />

Exacerbates, Pressure Overload-Induced Cardiac<br />

Fibrosis and Dysfunction<br />

Kaizheng Gong, Yiu‐Fai Chen, Peng Li, Wei Zhang,<br />

Fadi Hage, Namasivayam Ambalavanan, Suzanne<br />

Oparil, Dongqi Xing. University <strong>of</strong> Alabama at<br />

Birmingham, Birmingham, AL, US.<br />

PO-205: Left Ventricular Mass Index is Associated with<br />

Cognitive Impairment Independently <strong>of</strong> Blood<br />

Pressure in the Elderly<br />

Manabu Hayakawa, 1,2 Yuichiro Yano, 2,3 Kazuo<br />

Kuroki, 1 Kazuyuki Shimada, 3 Kazuomi Kario. 3<br />

1 Kushima Shimin Hospital, Miyazaki, JP; 2 University<br />

<strong>of</strong> Miyazaki, Miyazaki, JP; 3 Jichi Medical University<br />

School <strong>of</strong> Medicine, Tochigi, JP.<br />

PO-206: Heart Failure Hospitalization in Tennessee (2006-<br />

2008): Race, Age, and Gender Analyses<br />

Baqar Husaini†, 1 Van Cain, 1 Pamela Hull, 1 Zahid<br />

Samad, 1 H. Okafor, 2 Robert Levine, 2 U. Sampson. 3<br />

1 Tennessee State University, US; 2 Meharry Medical<br />

College, Nashville, TN, US; 3 Vanderbilt University,<br />

Nashville, TN, US.<br />

118


Sunday Morning MAY 22<br />

Posters<br />

PO-207:<br />

PO-208:<br />

PO-209:<br />

PO-210:<br />

PO-211:<br />

PO-212:<br />

Reverse Association <strong>of</strong> Early Relaxation Tissue<br />

Doppler Waves with Left Ventricle Mass in<br />

Hypertensive Non Diabetic Patients<br />

Athanasios N. Kartalis, Nikolaos E. Smyrnioudis,<br />

Stefanos H. Garoufalis, Georgios N. Benetos,<br />

Panagiotis M. Moschouris, Panagiotis D. Sgourakis,<br />

Nikolaos V. Papagiannis, Ioannis V. Georgiadis,<br />

Georgios E. Georgiopoulos. General Hopsital <strong>of</strong> Chios<br />

Island, Chios, GR.<br />

Association <strong>of</strong> Geometric Patterns <strong>of</strong> the Left<br />

Ventricle with Microalbuminuria in Hypertensive<br />

Non-Diabetic Patients<br />

Athanasios N. Kartalis, Nikolaos E. Smyrnioudis,<br />

Stefanos H. Garoufalis, Georgios N. Benetos,<br />

Panagiotis M. Moschouris, Panagiotis D. Sgourakis,<br />

Nikolaos V. Papagiannis, Georgios E. Georgiopoulos.<br />

General Hopsital <strong>of</strong> Chios Island, Chios, GR.<br />

Relation <strong>of</strong> Ventricular Geometry to Brain<br />

Natriuretic Peptide Levels, EF and NYHA Class in<br />

Heart Failure<br />

Sanjay Kumar, 1 Amit Nautiyal, 2 Jason Lazar. 1 1 SUNY<br />

Downstate Medical Center, Brooklyn, NY, US;<br />

2 University <strong>of</strong> Wisconsin, Madison, WI, US.<br />

The Influence <strong>of</strong> Telmisartan on Plasma Potassium<br />

Levels in Hypertensives with Insulin Resistance and<br />

Heart Failure<br />

Mariya A. Orynchak, Oleg M. Sheremeta, Nestor<br />

M. Seredyuk, Nadiya V. Skrypnyk. Ivano-Frankivsk<br />

National Medical University, Ivano-Frankivsk, UA.<br />

The Types <strong>of</strong> Left Ventricular Diastolic Dysfunction<br />

and Plasma NT-pro BNP Levels in Patients with<br />

Metabolic Syndrome<br />

Mariya A. Orynchak, Iryna I. Vakalyuk, Iryna O.<br />

Gaman. Ivano-Frankivsk National Medical University,<br />

Ivano-Frankivsk, UA.<br />

Postoperatiave B-Type Natriuretic Peptide Level<br />

Associates with Prolonged Hospitalization after<br />

Non-Cardiac Surgery in Patients with <strong>Hypertension</strong><br />

Wook Bum Pyun, 1 Jae Hong Park, 2 Sang‐Hak Lee, 3<br />

Wook‐Jin Chung, 4 Young‐Sup Byun, 5 Sung‐Kee Ryu, 6<br />

Se‐Joong Rim, 7 Gil Ja Shin. 1 1 Mokdong Hospital,<br />

School <strong>of</strong> Medicine, Ewha Womans University, Seoul,<br />

KR; 2 Kangnam General Hospital, Yongin, KR; 3 Yonsei<br />

Cardiovascular Center, Yonsei University College<br />

<strong>of</strong> Medicine, Seoul, KR; 4 Heart Center, Gachon<br />

University Gil Medical Center, Incheon, KR; 5 Sanggye<br />

Paik Hospital, Inje University College <strong>of</strong> Medicine,<br />

Seoul, KR; 6 Eulji General Hospital, Eulji University<br />

School <strong>of</strong> Medicine, Seoul, KR; 7 Gangnam Severance<br />

Hospital, Yonsei University College <strong>of</strong> Medicine, Seoul,<br />

KR.<br />

119


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-213:<br />

PO-214:<br />

PO-215:<br />

PO-216:<br />

Treatment Blocking the Renin-Angiotensin System<br />

and Two-Year Mortality in Very Old Patients with<br />

Heart Failure and Preserved Ventricular Ejection<br />

Fraction<br />

Carlos Rodriguez‐Pascual, 1 Emilio Paredes‐Galan, 3<br />

Arturo Vilches‐Moraga, 1 Ana Isabel Ferrero-<br />

Martinez, 1 Marta Torrente‐Carballido, 1 Fernando<br />

Rodríguez‐Artalejo. 2 1 Hospital Meixoeiro, Vigo,<br />

Pontevedra, ES; 2 Universidad Autonoma, Madrid, ES;<br />

3 Hospital Meixoeiro, Vigo, Pontevedra, ES.<br />

Left Ventricular Hypertrophy in Overweight/Obese<br />

Hypertensives with Metabolic Syndrome Depends<br />

on Body Mass Index<br />

Federico Guerra, Lucia Mancinelli, Luca Angelini,<br />

Marco Fortunati, Paolo Dessì-Fulgheri, Riccardo<br />

Sarzani. University Politecnica delle Marche, Ancona,<br />

IT.<br />

The Association <strong>of</strong> Left Ventricular Hypertrophy<br />

with Exercise Induced Intraventricular Asynchrony<br />

Hye‐Sun Seo, 1 Young‐Sup Byun, 2 Sung‐Kee Ryu, 3<br />

Wook‐Bum Pyun, 4 Se‐Joong Rim, 5 Wook‐Jin Chung, 6<br />

Sung‐Hee Shin. 7 1 Soonchunhyang University Hospital,<br />

Bucheon, KR; 2 Sanggye Paik Hospital, Inje University<br />

College <strong>of</strong> Medicine, Seoul, KR; 3 Eulji General<br />

Hospital, Eulji University School <strong>of</strong> Medicine, Seoul,<br />

KR; 4 Ewha Womans University Hospital, Seoul, KR;<br />

5 Gangnam Severance Hospital, Yonsei University<br />

College <strong>of</strong> Medicine, Seoul, KR; 6 Gachon University<br />

Gil Hospital, Gachon University School <strong>of</strong> Medicine,<br />

Incheon, KR; 7 Inha University Hospital, Incheon, KR.<br />

Gender Specific Prognostic Differences in Regard<br />

to the Regression <strong>of</strong> Hypertensive Left Ventricular<br />

Hypertrophy (12 Years Follow-Up Study)<br />

Ivan Tasic, 1 Svetlana Kostic, 1 Dragan Djordjevic, 1<br />

Gordana Lazarevic, 2 Dragan Lovic. 3 1 Institute for<br />

Therapy and Rehabilitation “Niska Banja”, Niska Banja,<br />

RS; 2 Clinic <strong>of</strong> Cardiology, Nis, RS; 3 Clinic for Internal<br />

Disease InterMedica-Dr Lovic, Nis, RS.<br />

<strong>Hypertension</strong> in patients with chronic<br />

kidney disease<br />

PO-217:<br />

PREdictors <strong>of</strong> Adequate Control <strong>of</strong> <strong>Hypertension</strong><br />

among Chronic Kidney Disease Patients (PREACH-<br />

CKD)<br />

Ma Czarlota M. Acelajado‐Valdenor, Angelo Dave C.<br />

Javier, Maria Czarina M. Acelajado. Philippine General<br />

Hospital, Manila, PH.<br />

120


Sunday Morning MAY 22<br />

Posters<br />

PO-218:<br />

PO-219:<br />

PO-220:<br />

PO-221:<br />

PO-222:<br />

PO-223:<br />

Prevalence, Awareness, Treatment and Control <strong>of</strong><br />

<strong>Hypertension</strong> in Chronic Kidney Disease<br />

Bulent Altun, 1 Gultekin Suleymanlar, 2 Cengiz Utas, 3<br />

Turgay Arinsoy, 4 Kenan Ates, 5 Tevfik Ecder, 6 Taner<br />

Camsari, 7 Kamil Serdengecti. 8 1 Hacettepe University<br />

Faculty <strong>of</strong> Medicine, Ankara, TR; 2 Akdeniz University<br />

Medical School, Antalya, TR; 3 Erciyes University<br />

Faculty <strong>of</strong> Medicine, Kayseri, TR; 4 Gazi University<br />

Faculty <strong>of</strong> Medicine, Ankara, TR; 5 Ankara University<br />

Faculty <strong>of</strong> Medicine, Ankara, TR; 6 Istanbul University<br />

Istanbul Faculty <strong>of</strong> Medicine, Istanbul, TR; 7 Dokuz<br />

Eylul University Faculty <strong>of</strong> Medicine, Izmir, TR;<br />

8 Istanbul University Cerrahpasa Faculty <strong>of</strong> Medicine,<br />

Istanbul, TR.<br />

Selective Endothelin-A Receptor Antagonism<br />

Reduces Proteinuria, Blood Pressure and Arterial<br />

Stiffness in Chronic Proteinuric Kidney Disease<br />

N. Dhaun, I. MacIntyre, J. Goddard, D. J. Webb.<br />

University <strong>of</strong> Edinburgh, GB.<br />

Discordant Estimation <strong>of</strong> the Prevalence <strong>of</strong> Masked<br />

<strong>Hypertension</strong> According to Daytime or Nighttime<br />

Blood Pressure in Subjects with Chronic Kidney<br />

Disease. The Hygia Project<br />

Ramon C. Hermida, 1 Alfonso Otero, 2 Luis Piñeiro, 3<br />

Diana E. Ayala, 1 Ana Moya, 4 Elvira Sineiro, 4 Maria<br />

J. Fontao, 1 Artemio Mojon, 1 Jose R. Fernandez, 1<br />

Investigadores Proyecto Hygia. 1 1 University <strong>of</strong> Vigo,<br />

Vigo, ES; 2 Complejo Hospitalario Universitario,<br />

Orense, ES; 3 Complejo Hospitalario Universitario,<br />

Pontevedra, ES; 4 Gerencia de Atención Primaria,<br />

Pontevedra, ES.<br />

Alteration <strong>of</strong> the Circadian Blood Pressure Pattern<br />

in Subjects with Chronic Kidney Disease: The Hygia<br />

Project<br />

Alfonso Otero, 1 Manuel Dominguez‐Sardiña, 2 Maria<br />

C. Castiñeira, 3 Juan J. Crespo, 2 Amelia Ferreras, 2<br />

Artemio Mojon, 4 Diana E. Ayala, 4 Jose R. Fernandez, 4<br />

Ramon C. Hermida, 4 Investigadores Proyecto Hygia. 4<br />

1 Complejo Hospitalario Universitario, Orense, ES;<br />

2 Gerencia de Atención Primaria, Vigo, ES; 3 Gerencia<br />

de Atención Primaria, Pontevedra, ES; 4 University <strong>of</strong><br />

Vigo, Vigo, ES.<br />

Usefulness <strong>of</strong> the Resistive Index in Renal Doppler<br />

Ultrasonography as an Indicator <strong>of</strong> Vascular<br />

Damage in Patients with Risks <strong>of</strong> Atherosclerosis<br />

Tatsuo Kawai, Kei Kamide, Miyuki Onishi, Hiroko<br />

Yamamoto‐Hanasaki, Yoshichika Baba, Kazuhiro<br />

Hongyo, Izumi Shimaoka, Yuji Tatara, Yasushi Takeya,<br />

Mitsuru Ohishi, Hiromi Rakugi. Osaka University<br />

Graduate School <strong>of</strong> Medicine, Suita, Osaka, JP.<br />

Intradialytic <strong>Hypertension</strong> is Not Associated with<br />

Increased Blood Pressure Variability<br />

Catherine Kim, Peter N. Van Buren, Robert Toto, Jula<br />

K. Inrig. University <strong>of</strong> Texas at Southwestern, Dallas,<br />

TX, US.<br />

121


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-224:<br />

PO-225:<br />

PO-226:<br />

Effect <strong>of</strong> Vitamin D Supplementation on Blood<br />

Pressure among HD Patients Undergoing Dialysis<br />

Bharadwaj Cheruvu, 1 Yap Jason, 1,2 Saklayen<br />

Mohammad. 1,2 1 Veterans Medical Center, Dayton, OH,<br />

US; 2 Wright State University, Dayton, OH, US.<br />

Heme Oxygenase Induction Prevents Endothelial<br />

Dysfunction and Renal Damage in ec-SOD KO Mice<br />

Nitin Puri, 1 Tomoko Kawakami, 1 Luca Vanella, 1 Lars<br />

Bellner, 2 Rita Rezzani, 3 Toru Takahashi, 4 Kiyoshi<br />

Morita, 4 Nader G. Abraham. 1 1 University <strong>of</strong> Toledo,<br />

Toledo, OH, US; 2 New York Medical College, Valhalla,<br />

NY, US; 3 University <strong>of</strong> Brescia, IT; 4 Okayama<br />

University Medical School, Okayama, JP.<br />

Mean Hemodialysis-Unit Systolic BP is Similar in<br />

Patients with and without Frequent Intradialytic<br />

<strong>Hypertension</strong><br />

Peter N. Van Buren, Catherine Kim, Robert D. Toto,<br />

Jula K. Inrig. University <strong>of</strong> Texas Southwestern<br />

Medical Center, Dallas, TX, US.<br />

Kidney and <strong>Hypertension</strong><br />

PO-227:<br />

PO-228:<br />

PO-229:<br />

PO-230:<br />

PO-231:<br />

Nighttime Hemodynamics and Arterial Stiffness<br />

Exert a Powerful Additive Predictive Effect on the<br />

Occurrence <strong>of</strong> Microalbuminuria in <strong>Hypertension</strong>:<br />

A 6-year Follow-Up Study<br />

E. Andrikou, C. Tsioufis, C. Thomopoulos, A. Kordalis,<br />

I. Andrikou, M. Giakoumis, L. Lioni, M. Almiroudi, I.<br />

Eleftheriadou, C. Stefanadis. Hippokration Hospital,<br />

Athens, GR.<br />

Learning Nephrology through Mobile Devices: The<br />

Nephrology On-Demand Mobile Experience<br />

Tejas Desai, 1 Maria Ferris. 2 1 East Carolina University<br />

Brody School <strong>of</strong> Medicine, US; 2 The University <strong>of</strong><br />

North Carolina at Chapel Hill, US.<br />

Characteristics <strong>of</strong> Hypertensive Patients Using<br />

Either Aliskiren or Other Antihypertensive<br />

Medications<br />

Debra F. Eisenberg†, 1 Jinhee Park, 2 Christy Fang, 1<br />

Jean Lian, 2 Andrea DeVries. 1 1 HealthCore, Inc.,<br />

Wilmington, DE, US; 2 Novartis Pharmaceuticals, East<br />

Hanover, NJ, US.<br />

The Dopamine D1-Like Receptors Interact with the<br />

a 1A Adrenergic Receptor in Human Renal Epithelial<br />

Tubule Cells<br />

Riley C. Ennis, Van Anthony M. Villar, Julie A. Jurgens,<br />

John E. Jones, Pedro A. Jose. Children National<br />

Medical Center, Washington, DC, US.<br />

Uncoupled NOS is a Major Source <strong>of</strong> Renal<br />

Superoxide in Angiotensin II-Induced <strong>Hypertension</strong><br />

Maria C. Gongora, Li Li, Wei Chen, Kin Lung Siu,<br />

David G. Harrison. Emory University, Atlanta, GA,<br />

US.<br />

122


Sunday Morning MAY 22<br />

Posters<br />

PO-232:<br />

PO-233:<br />

PO-234:<br />

PO-235:<br />

PO-236:<br />

PO-237:<br />

PO-238:<br />

Loss <strong>of</strong> SNX5 Impairs Dopamine D 1 Receptor<br />

Endocytosis and Recycling and Aggravates the<br />

Blood Pressure in SHR<br />

Van Anthony M. Villar, 1,2 Ines Armando, 1,2 Lauren<br />

C. Frazer, 2 Kristen M. Russo, 2 Patricia M. Notario, 2<br />

Hewang Li, 1,2 Hironobo Sanada, 3 Yingjin Luo, 2 Lauren<br />

Comisky, 2 Holly Ann Russell, 2 Yu Yang, 1 Pedro A.<br />

Jose, 1,2 John E. Jones. 1,2 1 Children’s National Medical<br />

Center, Washington, DC, US; 2 Georgetown University<br />

School <strong>of</strong> Medicine, Washington, DC, US; 3 Fukushima<br />

Medical University School <strong>of</strong> Medicine, Fukushima, JP.<br />

Ambulatory Blood Pressure Measurement in<br />

Patients with Chronic Kidney Disease: Outcomes<br />

and Correlation with Clinic BP and BpTRU<br />

Ashok L. Kirpalani, Aditya S. Bhabhe, Dilip A.<br />

Kirpalani, Hardik K. Shah. Bombay Hospital Institute<br />

<strong>of</strong> Medical Sciences, Mumbai, Maharashtra, IN.<br />

Perinatal Dietary Protein and NaCl on Offspring’s<br />

Ambulatory Blood Pressure and Renal Injury<br />

Jong Y. Lee, Silvia H. Azar. Univ <strong>of</strong> MN School <strong>of</strong><br />

Medicine, Minneapolis, MN, US.<br />

Effects <strong>of</strong> a Direct Renin Inhibitor on RRI in<br />

Hypertensive Patients<br />

Francesco Natale, Chiara Cirillo, Chiara Granato,<br />

Claudia Concilio, Alessandro Siciliano, Luigi Aronne,<br />

Maria Credendino, Emanuela Lo Priore, Alessandro<br />

Ranieri, Maria Giovanna Russo, Raffaele Calabrò.<br />

Second University <strong>of</strong> Naples, Monaldi Hospital,<br />

Naples, IT.<br />

Uncontrolled <strong>Hypertension</strong> in CKD Patients is<br />

Associated with Higher Heart Rate<br />

Alexander Kagan, 1,2,3 Hedy Feibel, 3 Ishay Shoval, 3<br />

Jayson Rapoport. 1,2 1 Kaplan Medical Center, Rehovot,<br />

IL; 2 Hebrew University, Jerusalem, IL; 3 ”Meuhedet”<br />

Sick Fund, IL.<br />

Analysis <strong>of</strong> Left Ventricular Function and <strong>of</strong><br />

Coronary Circulation in Relationship to Renal<br />

Function<br />

César S. Rosa, 1,2 Bruno B. Pelazza, 1,2 Sebastião R.<br />

Filho. 1 1 Federal University <strong>of</strong> Uberlândia, Uberlândia,<br />

Minas Gerais, BR; 2 Heart Institute <strong>of</strong> Triangulo<br />

Mineiro, Uberlândia, Minas Gerais, BR.<br />

Discrepancies in <strong>Hypertension</strong> Control Rates<br />

Evaluated by Means <strong>of</strong> Office BP and Ambulatory<br />

BP Monitoring in Hypertensive Patients with and<br />

without Chronic Kidney Disease<br />

Manuel Gorostidi, 1 Julian Segura, 2 Alejandro de la<br />

Sierra, 3 Juan J. de la Cruz, 4 Jose R. Banegas, 4 Luis M.<br />

Ruilope. 2 1 Hospital Central de Asturias, Oviedo, ES;<br />

2 Hospital 12 de Octubre, Madrid, ES; 3 Hospital Mutua<br />

Terrasa, Universidad de Barcelona, Barcelona, ES;<br />

4 Universidad Autónoma, Madrid, ES.<br />

123


MAY 22<br />

Posters<br />

Sunday Morning<br />

PO-239:<br />

PO-240:<br />

PO-241:<br />

PO-242:<br />

Impaired Coronary Microcirculation is Associated<br />

with Increased Urine Albumin Excretion in<br />

Untreated Hypertensives<br />

D. Tsiachris, C. Tsioufis, K. Dimitriadis, D. Rousos,<br />

I. Tatsis, A. Kordalis, A. Kefala, C. Stefanadis.<br />

Hippokration Hospital, Athens, GR.<br />

Associations <strong>of</strong> Renal Hemodynamics with Target<br />

Organ Damage in Untreated Hypertensives. An<br />

Invasive Approach<br />

C. Tsioufis, D. Tsiachris, K. Dimitriadis, D. Rousos, I.<br />

Tatsis, D. Syrseloudis, G. Latsios, V. Papademetriou, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Albuminuria is Related to Circulating Soluble<br />

Receptor for Advanced Glycation End Products<br />

and Biomarkers <strong>of</strong> Endothelial Function in<br />

<strong>Hypertension</strong><br />

C. Tsioufis, K. Dimitriadis, A. Aggelis, M. Poulakis, A.<br />

Kefala, A. Kasiakogias, A. Miliou, M. Almiroudi, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Chronic Kidney Disease Education in the<br />

Community Health Center Setting Improves<br />

Prescription Filling Rates for Antihypertensive<br />

Medications<br />

Paul Bolin, Cindy Christiano, Melanie Hames,<br />

Tejas Desai, Hsiao Lai, Karen Parker, Rachel Ward,<br />

Courtland Winborne, Lacy Dean. East Carolina<br />

University Brody School <strong>of</strong> Medicine, US.<br />

Off-target cardiovascular effects <strong>of</strong><br />

non-cardiovascular drugs<br />

PO-243:<br />

PO-244:<br />

Sitagliptin is Associated with Increased Blood<br />

Pressure in Rats<br />

Dov Gavish, 1,3 Eyal Leibovitz, 1,3 Yonatan Shrabi, 2,3<br />

Ehud Grosman, 2,3 Dror Harats. 2,3 1 Wolfson Hospital,<br />

Holon, IL; 2 Sheba Medical Center, Ramat Gan, IL; 3 Tel<br />

Aviv Univeristy, Tel Aviv, IL.<br />

Blood Pressure Evaluation in Oncology and CNS<br />

Indications: Implementation <strong>of</strong> ABPM and Home<br />

BP Telemonitoring<br />

Jeffrey Heilbraun. Scientific Affairs, Rockville, MD, US.<br />

124


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

Posters will be displayed in the Second Floor Promenade.<br />

Monday, May 23, <strong>2011</strong><br />

Posters on Display: 10:00 AM – 5:30 PM • Poster Viewing: 4:30 PM – 5:30 PM<br />

Featured Posters<br />

Cardiac Structure and Function.................................... (FP-9 – FP-13)<br />

Arterial Structure and Compliance...........................(PO-245 – PO-259)<br />

Blood Pressure Measurement/Monitoring............(PO-260 – PO-305A)<br />

Cellular Mechanisms (Cell Biology;<br />

Cell Membrane Transport/Ion Channels;<br />

Coagulation/Thrombosis; Growth Factors).............(PO-306 – PO-308)<br />

Lipid Metabolism...........................................................................(PO-309)<br />

Neutral Hormonal Mechanisms (Renin; Neutral Control; Vasoactive<br />

Autacoids.......................................................................(PO-310 – PO-312)<br />

Non – Pharmacological Therapy (Alternative<br />

Medicine; Diet; Physical Activity).............................(PO-313 – PO-322)<br />

Nutrition and Cardiovascular Prevention................(PO-323 – PO-330)<br />

Obesity...........................................................................(PO-331 – PO-339)<br />

Patient – Provider-Healthcare System Issues...........(PO-340 – PO-355)<br />

Preclinical Models/Experimental <strong>Hypertension</strong>.....(PO-357 – PO-358)<br />

Pregnancy......................................................................(PO-359 – PO-361)<br />

Salt-Sensitive Mechanisms <strong>of</strong> <strong>Hypertension</strong>............(PO-362 – PO-364)<br />

Secondary <strong>Hypertension</strong>.............................................(PO-365 – PO-367)<br />

Late-Breaking Posters.........................................(LB-PO-01 – LB-PO-03)<br />

Dagger (†) denotes that the presenting author has related disclosure<br />

information.<br />

125


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

10:00 AM – 5:30 PM • Second Floor Promenade<br />

Featured Posters – Cardiac Structure<br />

and Function<br />

Moderators:<br />

FP-9:<br />

FP-10:<br />

FP-11:<br />

FP-12:<br />

FP-13:<br />

John D. Bisognano, MD, PhD, Rochester, NY and<br />

Robert A. Phillips, MD, PhD, Worcester, MA<br />

Parallel Deterioration <strong>of</strong> Albuminuria, Arterial<br />

Stiffness and Left Ventricular Mass in Essential<br />

<strong>Hypertension</strong>: Integrating Target Organ Damage<br />

E. Andrikou, C. Tsioufis, K. Dimitriadis, D. Flessas, K.<br />

Kintis, I. Mpafakis, M. Almiroudi, G. Chlapoutakis, M.<br />

Poulakis, M. Giakoumis, C. Stefanadis. Hippokration<br />

Hospital, Athens, GR.<br />

The Prognostic Value <strong>of</strong> Left Ventricular<br />

Hypertrophy in the Very Elderly: The PROTEGER<br />

Study<br />

Yi Zhang, 1,2 Davide Agnoletti, 1 Julie Peroz, 1 Ari<br />

Lieber, 1 Pierre Iaria, 1 Athanase D. Protogerou, 3 Michel<br />

E. Safar, 1 Jacques Blacher. 1 1 Paris Descartes University,<br />

Paris, FR; 2 Jiaotong University School <strong>of</strong> Medicine,<br />

Shanghai, CN; 3 University <strong>of</strong> Athens, Athens, GR.<br />

Cornell Product Left Ventricular Hypertrophy<br />

in Electrocardiogram and Mortality in a General<br />

Population<br />

Joji Ishikawa, 1 Shizukiyo Ishikawa, 2 Kazunori Kayaba, 3<br />

Kazuomi Kario. 1 1 Jichi Medical University School<br />

<strong>of</strong> Medicine, Tochigi, JP; 2 Jichi Medical University,<br />

Tochigi, JP; 3 Saitama Prefectural University, Saitama,<br />

JP.<br />

Identification <strong>of</strong> Myocardial Viability in<br />

Hypertensive Patients Receiving Beta-Blockers by<br />

Dobutamine Echocardiography<br />

Fei Lu, Vitantonio Di Bello, Chunzeng Lu, Mario<br />

Marzilli, Alberto Balbarini. University <strong>of</strong> Pisa, IT.<br />

Targeted Delivery <strong>of</strong> Endothelial Cells<br />

Overexpressing IL8RA and IL8RB Receptors<br />

Promotes Structural and Functional Recovery <strong>of</strong><br />

the Left Ventricle in Rats Following Myocardial<br />

Infarction<br />

Peng Li, Dongqi Xing, Kaizheng Gong, Fadi Hage,<br />

Onyedika John IIonze, Suzanne Oparil, Yiu‐Fai Chen.<br />

UAB, Birmingham, AL, US.<br />

126


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

10:00 AM – 5:30 PM • Second Floor Promenade<br />

Arterial Structure and Compliance<br />

PO-245:<br />

PO-246:<br />

PO-247:<br />

PO-248:<br />

PO-249:<br />

PO-250:<br />

PO-251:<br />

PO-252:<br />

Vascular Injury in Hypertensive Patients. are Men<br />

and Women Equal PARITE Study<br />

Claire Mounier‐Vehier, 1 Simon Tabassome, 2<br />

Dominique Guedj, 3 Assya Achouba, 4 Emmanuel<br />

Ghannad, 5 Stéphane Quéré, 4 Maxime Guenoun. 6<br />

1 Cardiologic Hospital, Lille, FR; 2 CHU Saint-Antoine,<br />

Paris, FR; 3 Cardiologist, Paris, FR; 4 Novartis Pharma<br />

SAS, Rueil-Malmaison, FR; 5 Cardiologist, Gif sur<br />

Yvette, FR; 6 Cardiologist, Marseille, FR.<br />

Peripheral Pulse Pressure Strongly Correlates with<br />

Central Systolic Blood Pressure in Adults: Bogalusa<br />

Heart Study<br />

Rebecca I. Clark, Camilo Fernandez, Gerald S.<br />

Berenson, Thomas D. Giles, Gary E. Sander. Tulane<br />

University Health and Sciences Center, New Orleans,<br />

LA, US.<br />

Addition <strong>of</strong> Eplerenone to RAAS Blockade in<br />

Patients with CKD and Proteinuria Correlates with<br />

Baseline Vascular Compliance<br />

Debbie L. Cohen†, Kevin A. Sterling, Raymond R.<br />

Townsend. University <strong>of</strong> Pennsylvania, Philadelphia,<br />

PA, US.<br />

Arterial Stiffness Evaluation in HIV Patients<br />

Antonio J. Delgado‐Leon, 1 Zenaida Castillo, 1 Jose M.<br />

Rojas, 1 Susana I. Celis, 2 Jennifer Moreno. 1 1 University<br />

<strong>of</strong> Carabobo, Valencia, Carabobo, VE; 2 Instituto<br />

Docente de Urologia, Valencia, Carabobo, VE.<br />

A New Vibrational Approach for Carotid Pulse Wave<br />

Velocity Assessment<br />

Francesco Faita, 1 Vincenzo Gemignani, 1 Elisabetta<br />

Bianchini, 1 Rosa Maria Bruno, 2 Lorenzo Ghiadoni. 2<br />

1 Institute <strong>of</strong> Clinical Physiology – National Research<br />

Council, Pisa, IT; 2 University <strong>of</strong> Pisa, Pisa, IT.<br />

Central-Peripheral Blood Pressure Differences are<br />

Greater in Hispanics and African-<strong>American</strong>s<br />

Haroon Kamran, Louis Salciccioli, Rinkesh Patel,<br />

Mohamed Munshi, Stephen Littman, Jason Lazar.<br />

SUNY Downstate Medical Center, Brooklyn, NY, US.<br />

The Left Ventricular Septal – Aortic Angle<br />

Relationship with the Augmentation Index and<br />

Central Blood Pressures<br />

Mediha Ibrahim, Kinda Venner-Jones, Haroon<br />

Kamran, Louis Salciccioli, Carl Bastien, Jason Lazar.<br />

SUNY Downstate Medical Center, Brooklyn, NY, US.<br />

Differences in Post-Ischemic Reactive Hyperemia<br />

Tissue Oxygen Saturation between Normals and<br />

Hypertensive Subjects<br />

Revathy Thangaratnavel, Haroon Kamran, Louis<br />

Salciccioli, Wah Wah Htun, Ilir Maraj, Edinrin Rae<br />

Obasare, Jason Lazar. Downstate Medical Center,<br />

Brooklyn, NY, US.<br />

127


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-253:<br />

PO-254:<br />

PO-255:<br />

PO-256:<br />

PO-257:<br />

PO-258:<br />

PO-259:<br />

The Relationship between Impaired Lung Function<br />

and Cardiac Function in Older Individuals<br />

Barry J. McDonnell, 1 Iain Munnery, 2 Margaret M.<br />

Munnery, 2 Charlotte Bolton, 2 Carmel M. McEniery, 3<br />

Ian B. Wilkinson, 3 John R. Cockcr<strong>of</strong>t. 2 1 University<br />

<strong>of</strong> Wales Institute, Cardiff, Cardiff, GB; 2 Cardiff<br />

University, Cardiff, GB; 3 University <strong>of</strong> Cambridge,<br />

Cambridge, GB.<br />

Hyperemia Induced Changes in Carotid-Radial<br />

Pulse Wave Velocity before and after Pre and Post<br />

Ischemic Conditioning<br />

Nwamaka Onuigbo, Haroon Kamran, Louis Salciccioli,<br />

Abhishek Sharma, Jason Lazar. SUNY Downstate<br />

Medical Center, Brooklyn, NY, US.<br />

The Predictive Value <strong>of</strong> Carotid Artery Features over<br />

Traditional Risk Factors and Endothelial Function<br />

Oana Sandu, 1 Iulian Nastac, 2 Jaime Uribarri. 1 1 MSSM,<br />

NY, US; 2 UPB, Bucharest, RO.<br />

Determinants <strong>of</strong> Central Reflected Pressure Waves<br />

Sirisha Srikakarlapudi, Minesh Rajpal, Shaila Karan,<br />

Peter J. Osmond, Joseph L. Izzo. SUNY at Buffalo,<br />

Buffalo, NY, US.<br />

Regular Exercise-Induced Upregulation <strong>of</strong><br />

Circulating Endothelial Progenitor Cells Attenuates<br />

Age-Related Decline in Arterial Elasticity in Healthy<br />

Men<br />

Jun Tao, Zhen Yang. The First Affilaited Hospital. Sun<br />

Yat-Sen University, CN.<br />

Subendocardial Viability Ratio as an Index <strong>of</strong><br />

Impaired Coronary Flow Reserve in Untreated<br />

Hypertensives<br />

D. Tsiachris, C. Tsioufis, K. Dimitriadis, D. Rousos,<br />

A. Kordalis, I. Anastasopoulos, D. Syrseloudis, C.<br />

Stefanadis. Hippokration Hospital, Athens, GR.<br />

Impaired Coronary Microcirculation is Not<br />

Accompanied by Adverse Vascular Remodeling in<br />

Untreated Hypertensives<br />

D. Tsiachris, C. Tsioufis, D. Rousos, C. Thomopoulos,<br />

A. Kasiakogias, A. Kordalis, G. Latsios, C. Stefanadis.<br />

Hippokration Hospital, Athens, GR.<br />

Blood Pressure Measurement/Monitoring<br />

PO-260:<br />

Comparison <strong>of</strong> Central Hemodynamics between<br />

A_PULSE and Other Two Tonometry-Based Devices<br />

Yi Zhang, 1,2 Davide Agnoletti, 1 Julie Peroz, 1 Ari<br />

Lieber, 1 Michel E. Safar, 1 Paolo Salvi, 3,4 Jirar<br />

Topouchian, 1 Jacques Blacher. 1 1 Paris Descartes<br />

University, Paris, FR; 2 Jiaotong University School <strong>of</strong><br />

Medicine, Shanghai, CN; 3 University <strong>of</strong> Nancy, Nancy,<br />

FR; 4 University <strong>of</strong> Bologna, Bologna, IT.<br />

128


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-261:<br />

PO-262:<br />

PO-263:<br />

PO-264:<br />

PO-265:<br />

PO-266:<br />

PO-267:<br />

Two Office Blood Pressure Readings Taken on<br />

Each <strong>of</strong> Two Visits are Not Enough for an Accurate<br />

Estimation and an Adequate <strong>Hypertension</strong><br />

Diagnosis<br />

María M. Martínez, 1 María T. Díaz, 1 María T. Ríos, 1<br />

Rocío Del Tío, 1 Jesús Barros, 1 Victoria Mota, 1 Isabel<br />

Bueno, 1 Moncho Velhas, 1 Javier Pérez, 2 Ignacio<br />

Alonso. 2 1 Sergas (Health Department <strong>of</strong> Galicia), ES;<br />

2 University <strong>of</strong> Vigo, ES.<br />

Prevalence <strong>of</strong> Self-Monitoring Blood Pressure<br />

among Adults – Healthstyles, 2005 and 2008<br />

Carma Ayala, Xin Tong, Nora L. Keenan. CDC/<br />

NCCDPHP/DHDSP, Atlanta, GA, US.<br />

Prognostic Value <strong>of</strong> Clinic and Ambulatory Blood<br />

Pressure Measurements in Resistant <strong>Hypertension</strong><br />

Diana E. Ayala, 1 Ramon C. Hermida, 1 Artemio<br />

Mojon, 1 Luisa Chayan, 2 Maria J. Dominguez, 3 Maria<br />

J. Fontao, 1 Ignacio Alonso, 1 Jose R. Fernandez. 1<br />

1 University <strong>of</strong> Vigo, Vigo, ES; 2 Urgencias Sanitarias<br />

061 Galicia, Santiago, ES; 3 Policlinica La Rosaleda,<br />

Santiago, ES.<br />

Can Personal Exposures to Higher Nighttime<br />

and Early Morning Temperatures Increase Blood<br />

Pressure<br />

Robert D. Brook, 1 Hwashin H. Shin, 2 Robert L. Bard, 1<br />

Richard T. Burnett, 2 Alan Vette, 3 Carry Croghan, 3<br />

Ron Williams. 3 1 University <strong>of</strong> Michigan, US; 2 Health<br />

Canada, CA; 3 USEPA, US.<br />

24-h Ambulatory Blood Pressure and<br />

Cardiovascular Events in Elderly Hypertensive<br />

Patients Followed-Up for Seven Years<br />

Jose Mesquita Bastos, 1 Susana Bertoquini, 2 Jorge<br />

Polonia. 3 1 Universidade de Aveiro, Aveiro, PT;<br />

2 Faculdade Psicologia e Ciências da Educação, PT;<br />

3 Faculdade de Medicina do Porto, PT.<br />

Total Peripheral Resistance and its Relationship with<br />

<strong>Hypertension</strong> in Patients with Severe Sleep Apnea<br />

Ricardo M. Cabrera Sole, 1 Ramon Coloma, 1 Caridad<br />

Turpin Lucas, 1 Ana Galdamez Nuñez, 2 Erik Luepke, 3<br />

Juan Cañas, 4 Manuel Aguilera Saldaña. 1 1 University<br />

General Hospital <strong>of</strong> Albacete, Albacete, ES; 2 Health<br />

Center <strong>of</strong> Villacerrada, Albacete, ES; 3 University<br />

General Hospital “La Paz”, Madrid, ES; 4 Health Center<br />

No. 3, Albacete, ES.<br />

Patients with Hypertensive Crisis Have Higher Risk<br />

Following First Month after the Crisis Compared<br />

with Hypertensive Patients at Similar Blood<br />

Pressure<br />

Ricardo M. Cabrera Sole, 1 Caridad Turpin Lucas, 1 Ana<br />

Galdamez Nuñez, 2 Juan Cañas, 3 Manuel Aguilera<br />

Saldaña. 1 1 University General Hospital <strong>of</strong> Albacete,<br />

Albacete, ES; 2 Health Center <strong>of</strong> Villacerrada, Albacete,<br />

ES; 3 Health Center No. 3, Albacete, ES.<br />

129


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-268:<br />

PO-269:<br />

PO-270:<br />

PO-271:<br />

PO-272:<br />

PO-273:<br />

PO-274:<br />

PO-275:<br />

PO-276:<br />

Correlation between Left Ventricular Mass and<br />

Ambulatory or Clinic Blood Pressure in Very Elderly<br />

Subjects<br />

S. Carugo, 1 A. Esposito, 1 D. Solari, 1 M. Maisaidi, 1<br />

G. Mancia. 2 1 ASP IMMeS e PAT, University <strong>of</strong> Milan,<br />

Milan, IT; 2 University Milano-Bicocca, S. Gerardo<br />

Hospital, Monza, IT.<br />

Clinical and Ambulatory Blood Pressure Values in<br />

Centenaries<br />

S. Carugo, 1 A. Esposito, 1 D. Solari, 1 M. Maisaidi, 1<br />

G. Mancia. 2 1 ASP IMMeS e PAT, University <strong>of</strong> Milan,<br />

Milan, IT; 2 University Milano-Bicocca, S. Gerardo<br />

Hospital, Monza, IT.<br />

Usefulness <strong>of</strong> Automated Office Blood Pressure<br />

Measurement by BpTRU for the Diagnosis <strong>of</strong><br />

Resistant <strong>Hypertension</strong><br />

Giuseppe Crippa, 1 Antonino Cassi, 1 Matteo Bosi, 2<br />

Maria Luisa Fares. 1 1 Guglielmo da Saliceto Hospital,<br />

Piacenza, IT; 2 Universita’ Cattolica, Piacenza, IT.<br />

Effects <strong>of</strong> Aliskiren- and Ramipril-Based Treatment<br />

on Central Aortic Blood Pressure in Systolic<br />

<strong>Hypertension</strong><br />

Daniel Duprez†, 1 Fabio Baschiera, 2 Alan Charney, 3<br />

InYoung Baek, 2 Patrick Brunel. 2 1 University <strong>of</strong><br />

Minnesota, Minneapolis, MN, US; 2 Novartis Pharma<br />

AG, Basel, CH; 3 Novartis Pharmaceutical Corporation,<br />

East Hanover, NJ, US.<br />

Apparent Treatment Resistant <strong>Hypertension</strong> in a<br />

Community-Based Practice Network<br />

Brent Egan†, Yumin Zhao, W. Adam Brzezinski,<br />

Benjamin Clyburn, Jan Basile, Daniel Lackland.<br />

Medical University <strong>of</strong> South Carolina, Charleston, SC,<br />

US.<br />

Progression from Pre-<strong>Hypertension</strong> to <strong>Hypertension</strong><br />

is Accelerated in African <strong>American</strong>s<br />

Anbesaw Selassie, C. Shaun Wagner, Brent Egan†.<br />

Medical University <strong>of</strong> South Carolina, Charleston, US.<br />

Clinical Characteristics <strong>of</strong> Patients with<br />

Uncontrolled and Apparent Treatment Resistant<br />

<strong>Hypertension</strong>: NHANES 2005-2008<br />

Brent Egan†, 1 Yumin Zhao, 1 R. Neal Axon, 1 Keith<br />

Ferdinand. 2 1 Medical University <strong>of</strong> South Carolina,<br />

Charleston, SC, US; 2 Emory University, Atlanta, GA,<br />

US.<br />

Impacting Population Cardiovascular Health<br />

through a Community-Based Practice Network:<br />

Update on An-<strong>ASH</strong>-Supportive Collaborative<br />

Brent Egan†, Marilyn Laken, Daniel Lackland. Medical<br />

University <strong>of</strong> S.C., Charleston, SC, US.<br />

Estimation <strong>of</strong> Central Cardiovascular Parameters<br />

from Brachial Cuff Pressure Waveform<br />

Kenji Fujii, 1 Tatsuya Kobayashi, 1 Toshihiko Ogura, 1<br />

Hir<strong>of</strong>umi Tomiyama, 2 Akira Yamashina. 2 1 Omron<br />

Healthcare Co., Ltd, JP; 2 Tokyo Medical University, JP.<br />

130


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-277:<br />

PO-278:<br />

PO-279:<br />

PO-280:<br />

PO-281:<br />

PO-282:<br />

PO-283:<br />

Blood Pressure Measurement-Device and<br />

Calibration Patterns in Home Health Care<br />

F. W. Germino, 1,2 Megan M. Germino. 3 1 Orland<br />

Primary Care Specialists, Orland Park, IL, US; 2 Rush<br />

School <strong>of</strong> Medicine, Chicago, IL, US; 3 Rush University,<br />

Chicago, IL, US.<br />

ABPM in Octogenarians<br />

Eduardo Podjarny, 1 Jacques Bernheim, 1,2 Eliezer<br />

Golan. 1,2 1 Meir Medical Center, Kfar-Saba, IL; 2 Tel-<br />

Aviv University, Tel-Aviv, IL.<br />

Impact <strong>of</strong> Initial Antihypertensive Treatment with<br />

a Single-Pill Combination on Blood Pressure Goal<br />

Attainment: A Matched Cohort Study<br />

Alan H. Gradman†, 1 Hélène Parisé, 2 Marie‐Hélène<br />

Lafeuille, 2 Heather Falvey, 3 Patrick Lefebvre, 2 Mei<br />

Sheng Duh. 2 1 Temple University School <strong>of</strong> Medicine<br />

(Clinical Campus), Pittsburgh, PA, US; 2 Analysis<br />

Group, Inc., Boston, MA, US; 3 Novartis Pharma AG,<br />

Basel, CH.<br />

Influence <strong>of</strong> Dipping Classification on Fasting<br />

Glucose in Subjects with and without Elevated<br />

Ambulatory Blood Pressure: The Hygia Project<br />

Manuel Dominguez‐Sardiña, 1 Pedro A. Callejas, 1<br />

Peregrina Eiroa, 1 Juan J. Crespo, 1 Jose L. Salgado, 1<br />

Alfonso Otero, 2 Maria J. Fontao, 3 Sonia Lorenzo, 3<br />

Ramon C. Hermida, 3 Investigadores Proyecto Hygia. 3<br />

1 Gerencia de Atención Primaria, Vigo, ES; 2 Complejo<br />

Hospitalario Universitario, Orense, ES; 3 University <strong>of</strong><br />

Vigo, Vigo, ES.<br />

Influence <strong>of</strong> Duration <strong>of</strong> Ambulatory Blood Pressure<br />

Monitoring (48 vs. 24 Hours) on Cardiovascular<br />

Risk Assessment<br />

Ramon C. Hermida, Diana E. Ayala, Maria J. Fontao,<br />

Artemio Mojon, Jose R. Fernandez. University <strong>of</strong> Vigo,<br />

Vigo, ES.<br />

Reproducibility <strong>of</strong> Nocturnal Blood Pressure<br />

Dipping is Influenced by Day-to-Day Changes in<br />

Sleep Quality<br />

Alan L. Hinderliter, 1 Faye S. Routledge, 2 James A.<br />

Blumenthal, 2 William K. Wohlgemuth, 3 Andrew<br />

Sherwood. 2 1 University <strong>of</strong> North Carolina School<br />

<strong>of</strong> Medicine, Chapel Hill, NC, US; 2 Duke University<br />

Medical Center, Durham, NC, US; 3 University <strong>of</strong><br />

Miami School <strong>of</strong> Medicine, Miami, FL, US.<br />

Using Telephonic Outreach to Improve Blood<br />

Pressure Control<br />

Timothy Ho, 1 Joel Handler, 1 Michael Kanter, 2 Kristi<br />

Reynolds, 3 Ruthie Goldberg, 2 Joe Kimura. 1 1 Kaiser<br />

Permanente Medical Center, Anaheim, CA, US;<br />

2 Southern California Permanente Medical Group,<br />

Pasadena, CA, US; 3 Kaiser Permanente Southern<br />

California, Pasadena, CA, US.<br />

131


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-284:<br />

PO-285:<br />

PO-287:<br />

PO-288:<br />

PO-289:<br />

PO-290:<br />

PO-291:<br />

Relationship between the Reduction <strong>of</strong> Left<br />

Ventricular Mass Index and the Changes in Sleep<br />

Blood Pressure with Sodium Restriction and/or<br />

Diuretic Treatment<br />

Joji Ishikawa, Kazuo Eguchi, Satoshi Hoshide,<br />

Kazuyuki Shimada, Kazuomi Kario. Jichi Medical<br />

University School <strong>of</strong> Medicine, Tochigi, JP.<br />

BpTRU – A Useful Alternative to 24 Hour<br />

Ambulatory Blood Pressure Monitoring in<br />

Evaluation and Management <strong>of</strong> <strong>Hypertension</strong> in<br />

India<br />

Dilip A. Kirpalani, Hardik K. Shah, Aditya S. Bhabhe,<br />

Ashok L. Kirpalani. Bombay Hospital Institute <strong>of</strong><br />

Medical Sciences, Mumbai, Maharashtra, IN.<br />

Effects <strong>of</strong> Traffic-Related Particles on Blood Pressure<br />

and DNA Methylation<br />

Denise P. Lamoureux, Edgar A. Diaz, Yeonseung<br />

Chung, Mark S. Long, Joy Lawrence, Vasileios<br />

Papapostolou, Phuong‐son Nguyen, John J. Godleski.<br />

Harvard School <strong>of</strong> Public Health, US.<br />

Ambulatory Blood Pressure in the Biological Time<br />

Structures<br />

Mary S. Lee, 1 John S. Lee, 2 Jong Y. Lee, 3 Franz<br />

Halberg. 4 1 Northwestern Univ. School <strong>of</strong> Medicine,<br />

Chicago, IL, US; 2 Univ <strong>of</strong> Minnesota School <strong>of</strong><br />

Medicine, Minneapolis, MN, US.<br />

Ambulatory Blood Pressure Monitoring in<br />

Hypertensive Smokers: Evidence <strong>of</strong> Impaired Night-<br />

Response<br />

Linda Landini, 1 Aurelio Leone. 2 1 University <strong>of</strong> Pisa,<br />

Pisa, Pi, IT; 2 City Hospital, Massa, Ms, IT.<br />

Oscillometric and Auscultatory Blood Pressure<br />

Measurements before and after Acute Exercise and<br />

Rest in the Elderly<br />

Leandra Gonçalves Lima, Iara Felício Anunciato,<br />

Fernanda Jatte, Júlio Cesar Moriguti, Eduardo Ferriolli,<br />

Nereida K. Costa Lima. Ribeirao Preto Medical School<br />

Sao Paulo University, Ribeirao Preto, SP, BR.<br />

Home Blood Pressure Monitoring Requires<br />

Feedback to Patients to Improve Treatment <strong>of</strong><br />

<strong>Hypertension</strong><br />

Alexander G. Logan, 1 Warren McIsaac, 2 Jane Irvine, 3<br />

Andras Tisler, 4 Denice Feig, 5 Joseph Cafazzo. 6 1 Mount<br />

Sinai Hospital, Toronto, ON, CA; 2 Mount Sinai<br />

Hospital, Toronto, ON, CA; 3 York University, Toronto,<br />

ON, CA; 4 Semmelweis University, Budapest, HU;<br />

5 Mount Sinai Hospital, Toronto, ON, CA; 6 Toronto<br />

General Hospital, Toronto, ON, CA.<br />

132


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-292:<br />

PO-293:<br />

PO-294:<br />

PO-295:<br />

PO-297:<br />

PO-298:<br />

PO-299:<br />

Blood Pressure in Firefighters<br />

Steven M. M<strong>of</strong>fatt†, 1,4 Suchita Garg, 2 Michael J.<br />

Epstein, 2 Nandini Hadker, 2 Lora Lex, 1,4 Feride Frech-<br />

Tamas. 3 1 Indianapolis Fire Department, Indianapolis,<br />

IN, US; 2 United BioSource Corporation, Lexington,<br />

MA, US; 3 Novartis Pharmaceuticals, East Hanover, NJ,<br />

US; 4 Public Safety Medical, Indianapolis, IN, US.<br />

Long-Term Effects <strong>of</strong> Telemetric Blood Pressure<br />

Monitoring in Adequately Treated Patients with<br />

Arterial <strong>Hypertension</strong><br />

Claas L. Neumann, Eike M. Rieken, Jan‐Marc Schmidt<br />

Thrun, Egbert G. Schulz. Nephrologisches Zentrum<br />

Göttingen, Göttingen, Niedersachsen, DE.<br />

Relationship between Central and Peripheral Blood<br />

Pressure in Type 2 Diabetic and Prediabetic Patients<br />

Anna Oliveras, 1,3 Julián Segura, 3 Carmen Suárez, 3<br />

Manuel Gómez, 3 Luis García‐Ortiz, 3 Nieves Martell, 3<br />

María Abad, 3 Luis Vigil, 3 David Ferrero, 3 Juan J. de<br />

la Cruz, 2 Luis M. Ruilope, 3 Alejandro de la Sierra. 3<br />

1 Hosp.del Mar. Parc Salut Mar, Barcelona, ES;<br />

2 Autonomous University <strong>of</strong> Madrid, ES; 3 On Behalf <strong>of</strong><br />

the PRESCEN Study, ES.<br />

Clinical Characteristics, Blood Pressure Control,<br />

and Antihypertensive Treatment Patterns among<br />

Elderly Patients with <strong>Hypertension</strong><br />

Sujata P. Sarda, 1 Si‐Tien Wang, 1 Priyanka<br />

Ramamurthy, 1 Robert Wei, 1 Jinhee Park†, 2 L. M.<br />

Andrews, 2 Feride Frech‐Tamas, 2 Mei Sheng Duh. 1<br />

1 Analysis Group, Inc., Boston, MA, US; 2 Novartis<br />

Pharmaceuticals Corporation, East Hanover, NJ, US.<br />

Antihypertensive Effectiveness <strong>of</strong> Combination<br />

Lercanedipine with Diltiazemi in Patients with Mild<br />

to Moderate Arterial <strong>Hypertension</strong><br />

Oksana L. Rekovets, Yuriy M. Sirenko, Anna S.<br />

Dobrokhod, Galina F. Primak, Alla S. Vaschilko,<br />

Evhenia A. Pavlyuk. Institute <strong>of</strong> Cardiology, Kyiv, UA.<br />

Higher Night-Time Blood Pressure and Cardiac<br />

Damage in 1176 Patients: Effects <strong>of</strong> BMI and Drug<br />

Therapy<br />

Riccardo Sarzani, Federico Guerra, Massimiliano<br />

Fedecostante, Paolo Barbatelli, Elena Giannini, Letizia<br />

Lancioni, Emma Espinosa, Paolo Dessì‐Fulgheri.<br />

University Politecnica delle Marche, Ancona, IT.<br />

Seasonality <strong>of</strong> 24 H, Daytime and Night-Time Blood<br />

Pressure: Summer Does Not Always Mean Lower<br />

Federico Guerra, Massimiliano Fedecostante, Letizia<br />

Lancioni, Elena Giannini, Paolo Barbatelli, Emma<br />

Espinosa, Paolo Dessì‐Fulgheri, Riccardo Sarzani.<br />

University Politecnica delle Marche, Ancona, IT.<br />

133


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-300:<br />

PO-301:<br />

PO-302:<br />

PO-303:<br />

PO-304:<br />

PO-305:<br />

PO-305A:<br />

Improvement in <strong>Hypertension</strong> Control after a 2-Year<br />

Participation in a Web-Based <strong>Program</strong> on High BP<br />

Management<br />

Julian Segura, 1 Manuel Gorostidi, 2 Alejandro de la<br />

Sierra, 3 Jose R. Banegas, 4 Juan J. de la Cruz, 4 Luis<br />

M. Ruilope. 1 1 Hospital 12 de Octubre, Madrid, ES;<br />

2 Hospital Central de Asturias, Oviedo, ES; 3 Hospital<br />

Mutua Terrasa, Universidad de Barcelona, Barcelona,<br />

ES; 4 Universidad Autónoma, Madrid, ES.<br />

Ambulatory Blood Pressure Monitoring in<br />

Prehypertension<br />

Gabor Simonyi, Mihaly Medvegy. Flor Ferenc Hospital<br />

<strong>of</strong> County Pest, Kistarcsa, HU.<br />

Diagnostic Accuracy <strong>of</strong> Home Versus Ambulatory<br />

Blood Pressure Monitoring<br />

George S. Stergiou, Efthimia G. Nasothimiou, Dimitrios<br />

Tzamouranis, Vagia Rarra, Leonidas G. Roussias.<br />

University <strong>of</strong> Athens, Athens, GR.<br />

Patients’ Preference for Out-<strong>of</strong>-Office Blood<br />

Pressure Evaluation Method: Ambulatory or Home<br />

Monitoring<br />

Efthimia G. Nasothimiou, Nikolaos Karpettas,<br />

Antonios Destounis, George S. Stergiou. University <strong>of</strong><br />

Athens, Athens, GR.<br />

Preditive Value <strong>of</strong> Ambulatory Blood Pressure for<br />

Cardiovascular Events in Hypertensive Patients after<br />

a First Event<br />

Tiago Teixeira, 1 José Nuno Figueiredo, 1 Jose Mesquita<br />

Bastos, 1 Jose Nobre Santos, 1 Jorge Polonia. 2 1 Hospital<br />

Infante D.Pedro, EPE, Aveiro, PT; 2 Faculdade de<br />

Medicina do Porto, PT.<br />

Methods for Fast and Accurate Normalization <strong>of</strong><br />

Real-World Prescription Data: A Report from the<br />

O’QUIN <strong>Hypertension</strong> Initiative<br />

C. Shaun Wagner, Brent Egan. Medical University <strong>of</strong><br />

South Carolina, Charleston, SC, US.<br />

High Blood Pressure Treatment among Black and<br />

White Stroke Patients<br />

Andrea D. Boan, David L. Bachman, Robert J. Adams,<br />

Brent M. Egan, Joyce S. Nicholas, Andrew B. Lawson,<br />

Daniel T. Lackland. Medical University <strong>of</strong> South<br />

Carolina, Charleston, SC, US.<br />

Cellular Mechanisms (Cell Biology;<br />

Cell Membrane Transport/Ion Channels;<br />

Coagulation/Thrombosis; Growth<br />

Factors; Ion Channels)<br />

PO-306:<br />

Pharmacological Inhibition <strong>of</strong> PI3Kg Reduces Blood<br />

Pressure by a Vasorelaxant Akt/LTCC Mechanism<br />

Daniela Carnevale, 1 Giada Mascio, 1 Giuseppe Cifelli, 1<br />

Carmine Vecchione, 1 Giuseppe Lembo. 1,2 1 IRCCS<br />

Neuromed, Pozzilli, IT; 2 ”Sapienza” University <strong>of</strong><br />

Rome, Rome, IT.<br />

134


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-307:<br />

PO-308:<br />

<strong>Hypertension</strong> Induces b-Amyloid Deposition and<br />

Cognitive Impairment by Activating RAGE in Brain<br />

Endothelium<br />

Daniela Carnevale, 1 Giada Mascio, 1 Giuseppe Cifelli, 1<br />

Shi Du Yan, 3 Giuseppe Lembo. 1,2 1 IRCCS Neuromed,<br />

Pozzilli, IT; 2 ”Sapienza” University <strong>of</strong> Rome, Rome, IT;<br />

3 Columbia University, New York, US.<br />

Downmodulation <strong>of</strong> Peroxiredoxin-3 Expression in<br />

Cardiac Fibroblasts by Angiotensin II<br />

Paul J. Lijnen, Jos F. van Pelt. University <strong>of</strong> Leuvan<br />

(KULeuven), Leuven, BE.<br />

Lipid Metabolism<br />

PO-309:<br />

Does the Association between Lipid Pr<strong>of</strong>ile and<br />

Obesity Indices Vary through Decades in Essential<br />

Hypertensive Patients<br />

Stella Maria Kyvelou, 1 Gregory Vyssoulis, 1 Eva<br />

Karpanou, 2 I. Skoumas, 1 C. Stefanadis. 1 1 1st<br />

Cardiology Clinic Athens University Hippokration<br />

Hospital Athens Greece, GR; 2 1st Cardiology Clinic<br />

Onassis Cardiosurgery Center Athens, GR.<br />

Neural hormonal Mechanisms (Renin;<br />

Neural Control; Vasoactive Autacoids)<br />

PO-310:<br />

PO-311:<br />

PO-312:<br />

Long Term Follow-Up <strong>of</strong> Patients with Postural<br />

Orthostatic Tachycardia Syndrome<br />

Joao Freitas, 1,2 Alexandra Sousa, 1 Ana Lebreiro, 1 Maria<br />

Julia Maciel, 1,2 Francisco Rocha Goncalves. 2 1 Hospital<br />

de Sao Joao -E.P.E., Porto, PT; 2 Unoversidade do Porto,<br />

Porto, PT.<br />

Resistant <strong>Hypertension</strong> and Intravascular Volume<br />

Expansion<br />

Guilherme Augusto Mariano Pego, João Bernardo Pego,<br />

Maria Fátima Leitão, Helia Martins, Nadia Moreira,<br />

Luis Augusto Providência. University Hospital <strong>of</strong><br />

Coimbra, PT.<br />

Expression <strong>of</strong> the Renin-Angiotensin System in a<br />

Human Placental Cell Line<br />

Nan Pan, 1 Wayne L. Frome, 1 Richard A. Dart, 1 Duane<br />

A. Tewksbury, 1 Jiangming Luo. 2 1 Marshfield Clinic<br />

Research Foundation, Marshfield, WI, US; 2 Marshfield<br />

Clinic, Marshfield, WI, US.<br />

135


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

Non-Pharmacological Therapy<br />

(Alternative Medicine; Diet; Physical<br />

Activity)<br />

PO-313:<br />

PO-314:<br />

PO-315:<br />

PO-316:<br />

PO-317:<br />

PO-318:<br />

PO-319:<br />

The HARMONY Study: <strong>Hypertension</strong> Analysis <strong>of</strong><br />

Stress Reduction Using Mindfulness Meditation and<br />

Yoga<br />

Kimberly C. Blom, 1 Brian Baker, 2 Jane Irvine, 4 Susan<br />

Abbey, 2 Beth Abramson, 3 Martin Myers, 1 Nancy<br />

Perkins, 1 Sheldon W. Tobe. 1 1 Sunnybrook Health<br />

Sciences Centre, Toronto, ON, CA; 2 University Health<br />

Network, Toronto, ON, CA; 3 St. Michael’s Hospital,<br />

Toronto, ON, CA; 4 York University, Toronto, ON, CA.<br />

Impact <strong>of</strong> Smoking Cessation on Nocturnal Blood<br />

Pressure<br />

Patrick T. Campbell, Carla J. Rash, Sheila M. Alessi,<br />

Nancy M. Petry, William B. White. University <strong>of</strong><br />

Connecticut, Farmington, CT, US.<br />

Leisure Physical Activity and Emergent<br />

Cardiovascular Risk Factors in Hypertensive<br />

Patients<br />

Cristiana Catena, GianLuca Colussi, Andrea Russo,<br />

Gabriele Brosolo, Leonardo A. Sechi. University <strong>of</strong><br />

Udine, IT.<br />

Aerobic Exercise Training Improves Renal Function<br />

in African <strong>American</strong>s<br />

Keith M. Diaz, 1 Deborah L. Feairheller, 1 Kathleen<br />

M. Sturgeon, 1 Praveen Veerabhadrappa, 1 Sheara<br />

Williamson, 1 Jan Kretzschmar, 1 Michael D. Brown. 1<br />

1 Temple University, Philadelphia, PA, US; 2 Temple<br />

University, Philadelphia, PA, US.<br />

Actions to Control <strong>Hypertension</strong> among Adults with<br />

<strong>Hypertension</strong><br />

Jing Fang, Nora L. Keenan. CDC, Atlanta, GA, US.<br />

Exercise Capacity is Inversely Related to Mortality<br />

Risk in Hypertensive Individuals with Sleep Apnea<br />

Peter Kokkinos, 1,2,3 Shikha Khosla, 1 Marshal Balish, 1<br />

Raya Kheirbek, 1 Helen Sheriff, 1 Eric Nylen, 1,3<br />

Charles Faselis. 1,3 1 Veterans Affairs Medical Center,<br />

Washington, DC, US; 2 Georgetown University<br />

School <strong>of</strong> Medicine, Washington, DC, US; 3 George<br />

Washington University School <strong>of</strong> Medicine,<br />

Washington, DC, US.<br />

Heart Rate Recovery, Fitness and Mortality Risk in<br />

Hypertensive Individuals<br />

Peter Kokkinos, 1,2,3 Charles Faselis, 1,3 Michael<br />

Doumas, 1,3 Ross Fletcher, 1,2 Andreas Pittaras, 1<br />

Athanasios Manolis, 1 Rhea Kheirbek, 1 Vasilios<br />

Papademetriou. 1,2 1 Veterans Affairs Medical Center,<br />

Washington, DC, US; 2 Georgetown University<br />

School <strong>of</strong> Medicine, Washington, DC, US; 3 George<br />

Washington University, Washington, DC, US.<br />

136


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-321:<br />

PO-322:<br />

The Cost-Effectiveness <strong>of</strong> Interventions Designed to<br />

Reduce Sodium Intake<br />

Guijing Wang, Darwin Labarthe. Centers for Disease<br />

Control and Prevention, Atlanta, GA, US.<br />

Seasonal Effects <strong>of</strong> Blood Pressure in<br />

Postmenopausal Women<br />

Adrian D. Wood, 1 Frank Thies, 1 William D. Fraser, 2<br />

Lorna Aucott, 1 Karen R. Secombes, 1 William G.<br />

Simpson, 3 David M. Reid, 1 Helen M. Macdonald. 1<br />

1 University <strong>of</strong> Aberdeen, Aberdeen, GB; 2 University <strong>of</strong><br />

Liverpool, Liverpool, GB; 3 Aberdeen Royal Infirmary,<br />

Aberdeen, GB.<br />

Nutrition and Cardiovascular<br />

Prevention<br />

PO-323:<br />

PO-324:<br />

PO-325:<br />

PO-325A:<br />

PO-326:<br />

Antihypertensive Effect <strong>of</strong> Dietary Integration with<br />

Grana Padano Cheese in Hypertensive Patients<br />

Giuseppe Crippa, 1 Matteo Bosi, 2 Cassi Antonino, 1<br />

Lucia Fiorentini, 2 Filippo Rossi. 2 1 Guglielmo da<br />

Saliceto Hospital, Piacenza, IT; 2 Universita’ Cattolica<br />

del Sacro Cuore, Piacenza, IT.<br />

Abnormal Circadian Blood Pressure Variability in<br />

Healthy Adults: A Function <strong>of</strong> Weight Gain, Increase<br />

in Waist Circumference and Insulin Resistance<br />

Alok K. Gupta, 1 Germaine G. Cornelissen‐Guillaume, 2<br />

William D. Johnson, 1 Frank L. Greenway, 1 Darcy<br />

Johannsen, 1 Eric Ravussin. 1 1 Pennington Biomedical<br />

Research Center, Louisiana State University System,<br />

Baton Rouge, LA, US; 2 University <strong>of</strong> Minnesota,<br />

Minneapolis, MN, US.<br />

Endothelial Dysfunction in Healthy Adults:<br />

A Function <strong>of</strong> Weight Gain, Increase in Waist<br />

Circumference and Insulin Resistance<br />

Alok K. Gupta, William D. Johnson, Darcy Johannsen,<br />

Eric Ravussin. Pennington Biomedical Research<br />

Center, Louisiana State University System, Baton<br />

Rouge, LA, US.<br />

Dysglycemia Induces Abnormal Circadian<br />

Variability <strong>of</strong> Blood Pressure<br />

Alok K. Gupta, 1 Kathirvel Gopalakrishnan, 2 Sivarajan<br />

Kumarasamy, 2 William D. Johnson, 1 Bina Joe. 2<br />

1 Pennington Biomedical Research Center, Louisiana<br />

State University System, Baton Rouge, LA, US;<br />

2 University <strong>of</strong> Toledo College <strong>of</strong> Medicine, Toledo,<br />

OH, US.<br />

Relationship between Salt Intake and Central<br />

Aortic Hemodynamics in a Cohort <strong>of</strong> Untreated<br />

Hypertensive Patients<br />

Jorge J. Polonia, Jose A. Silva, Susana P. Bertoquini,<br />

Barbosa Loide. Faculdade Medicina Porto, Matosinhos<br />

Porto, PT.<br />

137


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-327:<br />

PO-328:<br />

PO-329:<br />

PO-330:<br />

Effect <strong>of</strong> Lifestyle Modification in Menopausal<br />

Women with Obesity, <strong>Hypertension</strong>, Autonomic and<br />

Endothelial Dysfunction<br />

Rosa M. Santos, 1 Joao Freitas, 1 Agostinho Monteiro, 3<br />

Espiga Macedo, 3 Eduardo Tejera, 2 Irene Rebelo. 2<br />

1 Hospital S Joao, Porto, PT; 2 Faculty Pharmacy, Porto,<br />

PT; 3 Faculty Medicine, Porto, PT.<br />

At Risk Older Latino Men and Women: Blood<br />

Pressure, Body Mass Index and D<strong>ASH</strong> Accordance<br />

Beth A. Staffileno, 1 Christy Tangney, 1 David X.<br />

Marquez, 2 Louis Fogg, 1 Eduardo E. Bustamante, 2<br />

Martha Clare Morris, 1 Ruby Hoyem, 1 Alexis<br />

Manning, 1 JoEllen Wilbur. 1 1 Rush University Medical<br />

Center, Chicago, IL, US; 2 University <strong>of</strong> Illinois at<br />

Chicago, Chicago, IL, US.<br />

Medical Avatar Can Select Patients with<br />

Cardiovascular Risk Factors<br />

Jerzy T. Tyszkiewicz, Bartosz Symonides, Zbigniew<br />

Gaciong. Medical University <strong>of</strong> Warsaw, Warsaw, PL.<br />

Aerobic Exercise Training Improves Endothelial<br />

Function in Pre-Hypertensive African <strong>American</strong>s<br />

Sheara T. Williamson, Deborah L. Feairheller, Kathleen<br />

M. Sturgeon, Praveen Veerabhadrappa, Michael<br />

D. Brown, Jan Kretzschmar. Temple University,<br />

Philadelphia, PA, US.<br />

Obesity<br />

PO-331:<br />

PO-332:<br />

PO-334:<br />

PO-335:<br />

The Effect <strong>of</strong> BMI on the Systemic Catecholamine<br />

and Haemodynamic Response to Increased<br />

Sympathetic Activity in Young Adults: A Pilot Study<br />

James M. Coulson†, John R. Cockcr<strong>of</strong>t. Cardiff<br />

University, Cardiff, Wales, GB.<br />

Aldosterone Release is Positively Correlated with<br />

Increasing Body Weight in Patients with Resistant<br />

<strong>Hypertension</strong><br />

Tanja Dudenbostel, Maria Czarina Acelajado, Roberto<br />

Pisoni, Suzanne Oparil, David A. Calhoun. Vascular<br />

Biology and <strong>Hypertension</strong>, University <strong>of</strong> Alabama at<br />

Birmingham, Birmingham, AL, US.<br />

Beta2-Adrenoceptor Polymorphisms (Arg16Gly)<br />

Accompanying High Plasma Norepinephrine is<br />

Related to Cardiovascular and Renal Complications<br />

in Obese Subjects<br />

Kazuko Masuo, 1 Hiromi Rakugi, 2 Toshio Ogihara, 2<br />

Murray D. Esler, 1 Gavin W. Lambert. 1 1 Baker IDI<br />

Heart & Diabetes Institute, Melbourne, VIC, AU;<br />

2 Osaka University Graduate School <strong>of</strong> Medicine, Suita,<br />

Osaka, JP.<br />

Efficacy <strong>of</strong> an Amlodipine/Olmesartan Medoxomil<br />

Algorithm on BP Control in Obese Patients<br />

Uncontrolled by Monotherapy<br />

Joel M. Neutel†, 1 Willa Hsueh, 2 Ali Shojaee, 3 William F.<br />

Waverczak, 3 Jen‐Fue Maa. 3 1 Orange County Research<br />

Center, US; 2 The Methodist Hospital Research<br />

Institute, US; 3 Daiichi Sankyo, Inc., US.<br />

138


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-336:<br />

PO-337:<br />

PO-338:<br />

PO-339:<br />

Resolution <strong>of</strong> <strong>Hypertension</strong> after Adjustable Gastric<br />

Banding – 1 Year Interim Results <strong>of</strong> the LAP-BAND<br />

AP® EXperience (APEX) Study<br />

John Dixon, 1 Michael Oefelein, 2 Ted Okerson†. 2<br />

1 Monash University, Melbourne, AU; 2 Allergan, Inc,<br />

Irvine, CA, US.<br />

Initial Aliskiren/HCTZ Combination Therapy<br />

Lowers BP in Obese Patients with Stage 2<br />

<strong>Hypertension</strong> and Type 2 Diabetes<br />

Raymond R. Townsend, 1 Alan Forker, 2 Thomas<br />

Severin, 3 Cheraz Cherif Papst, 3 Anthony Yadao. 4<br />

1 University <strong>of</strong> Pennsylvania Medical Center,<br />

Philadelphia, PA, US; 2 St Luke’s Lipid and Diabetes<br />

Research Center, Kansas City, MO, US; 3 Novartis<br />

Pharma AG, Basel, CH; 4 Novartis Pharmaceuticals<br />

Corporation, East Hanover, NJ, US.<br />

Aliskiren/HCTZ Inhibits RAAS Activity in Obese<br />

and Non-Obese Patients with Stage 2 <strong>Hypertension</strong><br />

and Type 2 Diabetes<br />

Raymond R. Townsend, 1 Alan Forker, 2 Thomas<br />

Severin, 3 Cheraz Cherif Papst, 3 Anthony Yadao. 4<br />

1 University <strong>of</strong> Pennsylvania Medical Center,<br />

Philadelphia, PA, US; 2 St Luke’s Lipid and Diabetes<br />

Research Center, Kansas City, MO, US; 3 Novartis<br />

Pharma AG, Basel, CH; 4 Novartis Pharmaceuticals<br />

Corporation, East Hanover, NJ, US.<br />

Aliskiren/Amlodipine Combination Lowers BP in<br />

Obese and Non-Obese Patients with Moderate-to-<br />

Severe <strong>Hypertension</strong><br />

Rudiger C. Braun‐Dullaeus, 1 Sergey B. Shustov, 2<br />

Carmen Alvarez, 3 Gregorio G. Rogelio, 4 Cheraz Cherif<br />

Papst, 5 Jack Zhang†. 6 1 Otto-von-Guericke University,<br />

Magdeburg, DE; 2 State Educational Institution <strong>of</strong><br />

High Pr<strong>of</strong>essional Education, St Petersburg, RU; 3 ABS<br />

Centelles, Barcelona, ES; 4 St Luke’s Medical Center,<br />

Quezon, PH; 5 Novartis Pharma AG, Basel, CH;<br />

6 Novartis Pharmaceuticals Corporation, East Hanover,<br />

NJ, US.<br />

Patient-Provider-Healthcare System<br />

Issues<br />

PO-340:<br />

PO-341:<br />

Clinical Inertia in <strong>Hypertension</strong>: Identifying<br />

Barriers to Improve Quality<br />

Bryan Batson, 1 JaNae Joyner, 2 Philip Mellen, 1 William<br />

Smith. 1 1 Hattiesburg Clinic, Hattiesburg, PA, US; 2 The<br />

Consortium for Southeastern <strong>Hypertension</strong> Control<br />

(COSEHC), Winston-Salem, NC, US.<br />

Renal Artery Stent Management: A Survey <strong>of</strong> Local<br />

Practice Patterns<br />

Frank K. Boateng, Daniel L. Landry, Barbara A. Greco.<br />

Baystate Medical Center, Springfield, MA, US.<br />

139


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

PO-342:<br />

PO-343:<br />

PO-344:<br />

PO-345:<br />

PO-346:<br />

PO-347:<br />

Impact <strong>of</strong> Switching from Valsartan to a Lower-<br />

Tiered Angiotensin Receptor Blocker on Subsequent<br />

Treatment Patterns<br />

E. K. Buysman†, 1 L. M. Andrews, 2 T. J. Bancr<strong>of</strong>t, 1 H.<br />

B. Dastani, 2 J. Zhang, 2 M. L. Monsalvo. 3 1 i3 Innovus,<br />

Eden Prairie, MN, US; 2 Novartis Pharmaceuticals<br />

Corporation, East Hanover, NJ, US; 3 i3 Research,<br />

Buenos Aires, AR.<br />

<strong>Hypertension</strong> Specialists’ Current and Potential<br />

Impact on Resistant <strong>Hypertension</strong> in the Medicare<br />

Population<br />

William J. Elliott†, 1 Brent M. Egan, 2 Thomas D. Giles, 3<br />

George L. Bakris, 4 Torry Mark Sansone. 5 1 Pacific<br />

Northwest University <strong>of</strong> Health Sciences, Yakima, WA,<br />

US; 2 Medical University <strong>of</strong> South Carolina, Charleston,<br />

SC, US; 3 Tulane University School <strong>of</strong> Medicine, New<br />

Orleans, LA, US; 4 The University <strong>of</strong> Chicago, Chicago,<br />

IL, US; 5 The <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, New<br />

York, NY, US.<br />

Mitigating Risk – Cardiovascular Health Assessment<br />

for the Men/Ms <strong>of</strong> Paterson and Passaic County –<br />

MR CHAMMP<br />

Robert T. Faillace, Margaret Latrella, Carolyn Strimike,<br />

Deborah Terrone, James Pruden, Ken Morris, Kathleen<br />

Sauter. St. Joseph’s Healthcare System, Paterson, NJ,<br />

US.<br />

Quantification <strong>of</strong> Clinical Inertia during GP’s<br />

Management <strong>of</strong> Uncontrolled Hypertensive Patients<br />

– Clepsydre Study<br />

Xavier Girerd, 1 Béatrice Fiquet, 2 Stéphane Quéré, 2<br />

Alain Francillon. 2 1 Pitié-Salpétrière Hospital, Paris, FR;<br />

2 Novartis Pharma SAS, Rueil-Malmaison, FR.<br />

Time to Talk CARDIO Communication Tool Use<br />

Improves Cardiovascular Disease Management<br />

Behaviors and Satisfaction<br />

Brian Forrest, 1 Stephanie Brinson, 1 Susan Harris<br />

Bavisotto, 1 JaNae Joyner. 2 1 Access Healthcare,<br />

Apex, NC, US; 2 The Consortium for Southeastern<br />

<strong>Hypertension</strong> Control (COSEHC), Winston Salem,<br />

NC, US.<br />

Automated Outreach for Antihypertensive<br />

Medication Refill Reminders<br />

Kelley R. Green, 1 Joel Handler, 2 Southida S.<br />

Vansomphone, 3 Claire Mesirov, 4 Kristi Reynolds. 4<br />

1 Kaiser Permanente Southern California Permanente<br />

Medical Group, Pasadena, CA, US; 2 Kaiser Permanente<br />

Medical Center, Anaheim, CA, US; 3 Kaiser<br />

Permanente, Downey, CA, US; 4 Kaiser Permanente<br />

Southern California, Pasadena, CA, US.<br />

140


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-348:<br />

PO-350:<br />

PO-351:<br />

PO-352:<br />

PO-353:<br />

PO-354:<br />

PO-355:<br />

Impact <strong>of</strong> Non-Medical Switching between Different<br />

Angiotensin Receptor Blockers on Blood Pressure<br />

and Medical Resource Utilization<br />

Khalid M. Kamal†, 1 Christopher Zacker, 2 Louis<br />

Civitarese. 3 1 Duquesne University Mylan School<br />

<strong>of</strong> Pharmacy, Pittsburgh, PA, US; 2 Novartis<br />

Pharmaceuticals Corporation, Emmaus, NJ, US;<br />

3 Preferred Primary Care Physicians, Pittsburgh, PA,<br />

US.<br />

Simple Drug Preference Questions are Predictive <strong>of</strong><br />

Antihypertensive Response: A STITCH2 Substudy<br />

Sigrid A. Nelson, 1 George K. Dresser, 2,3 Jeffrey L.<br />

Mahon, 1,2,3 Brian G. Feagan, 1,2,3 Guang Y. Zou, 1,3<br />

Margaret K. Vandervoort, 1 Cindy J. Wong, 1 Ross D.<br />

Feldman. 1,2,3 1 Robarts Research Institute, CA; 2 London<br />

Health Sciences Centre, CA; 3 University <strong>of</strong> Western<br />

Ontario, CA.<br />

Increased Clinical Outcomes at One Year Follow-Up<br />

Found in a Diabetic Patient-Centered Medical Home<br />

Pilot <strong>Program</strong><br />

Jennifer O’Donnell, 1 Cyndi Shull, 2 Amber Winkler, 1<br />

JaNae Joyner, 3 Laura Long. 2 1 Palmetto Primary Care<br />

Physicians, US; 2 Blue Cross and Blue Shield <strong>of</strong> South<br />

Carolina, US; 3 The Consortium for Southeastern<br />

<strong>Hypertension</strong> Control, Winston-Salem, NC, US.<br />

Single Pill vs Free-Equivalent Combination<br />

Therapies for <strong>Hypertension</strong>: Meta-Analysis <strong>of</strong><br />

Adherence and Costs<br />

Beth Sherrill, 1 Michael Halpern, 2 Sumeet Panjabi†, 3<br />

Shahnaz Khan, 1 Jie Zhang. 1 1 RTI Health Solutions,<br />

Research Triangle Park, NC, US; 2 RTI International,<br />

Washington, DC, US; 3 Daiichi Sankyo, Inc, Parsippany,<br />

NJ, US.<br />

Differences and Similarities in Explanatory Models<br />

<strong>of</strong> <strong>Hypertension</strong> in the U.S., Tanzania and Jamaica<br />

John Purakal, 1 Jean Williams‐Johnson, 2 Eric Williams, 2<br />

Ibtissam Ammary, 3 Senga Pemba, 4 Joseph Kambona, 4<br />

Robert Welch, 1 John Flack, 1 Phillip Levy. 1 1 Wayne<br />

State University School <strong>of</strong> Medicine, Detroit, MI,<br />

US; 2 University Hospital <strong>of</strong> the West Indies, JM;<br />

3 University <strong>of</strong> Michigan School <strong>of</strong> Public Health,<br />

Ann Arbor, MI, US; 4 Tanzanian Training Centre for<br />

International Health, TZ.<br />

Treat to Target using Interactive Voice Messaging<br />

to Enhance Primary Care Physican Management <strong>of</strong><br />

<strong>Hypertension</strong><br />

Graham A. Scott. Kaiser Permanente Medical Center,<br />

Riverside, CA, US.<br />

Is Poor Blood Pressure Control in Patients<br />

Presenting for Elective Surgery Predictable<br />

Patrick E. Benedict, Sachin Kheterpal, Amy M. Shanks,<br />

Alan B. Weder. University <strong>of</strong> Michigan, Ann Arbor,<br />

MI, US.<br />

141


MAY 21 23<br />

Posters<br />

Monday Afternoon<br />

Morning<br />

Preclinical Models/Experimental<br />

<strong>Hypertension</strong><br />

PO-357:<br />

PO-358:<br />

Paraventricular Nucleus <strong>of</strong> the Hypothalamus<br />

Neurons Project to Parasympathetic Brainstem<br />

Neurons that Control Heart Rate<br />

David Mendelowitz, Ramon Pinol. George Washington<br />

University, Washington, DC, US.<br />

Effects <strong>of</strong> Sex on Sympathetic Neural and<br />

Hemodynamic Responses to Head-Up Tilt in<br />

Hypertensive Seniors<br />

Yoshiyuki Okada, 1,2 M. Melyn Galbreath, 1,2 Shigeki<br />

Shibata, 1,2 Sara S. Jarvis, 1,2 Tiffany B. VanGundy, 1<br />

Rhonda L. Meier, 1 Wanpen Vongpatanasin, 2 Benjamin<br />

D. Levine, 1,2 Qi Fu. 1,2 1 Institute for Exercise and<br />

Environmental Medicine, Texas Health Presbyterian<br />

Hospital, Dallas, TX, US; 2 The UT Southwestern<br />

Medical Center at Dallas, Dallas, TX, US.<br />

Pregnancy<br />

PO-359: Autoantibodies to the Angiotensin II Type 1<br />

Receptor in Preeclampsia<br />

Maciej Adamczyk, R. Jeffrey Brashear, Stephen C. Hsu,<br />

Phillip G. Mattingly. Abbott Laboratories, Abbott Park,<br />

IL, US.<br />

PO-360: The Correlation between the Serum Testosterone<br />

Level and Insulin Sensitivity in Pre-Eclampsia –<br />

Eclampsia Syndrome<br />

M. Yousri K. Amin, Ibrahim L. Abdellatifi, Yousri<br />

A. Mohyeldin, Abdelmoneim A. Fawzy, Akram A.<br />

Deghedi, Mohamed A. Harb. Alexandria University,<br />

Alexandria, EG.<br />

PO-361: Effects <strong>of</strong> High Altitude and Ancestry on Uterine<br />

Artery Shear Stress and Blood Pressure in Normal<br />

Pregnant vs. Preeclamptic Women<br />

Ronald Magness, 1 Ira Bernstein, 2 Stacy Zamadio. 3<br />

1 University <strong>of</strong> Wisconsin - Madison, Madison, WI,<br />

US; 2 University <strong>of</strong> Vermont, Vermont, US; 3 New Jersey<br />

Medical School, New Jersey, US.<br />

Salt-Sensitive Mechanisms <strong>of</strong><br />

<strong>Hypertension</strong><br />

PO-362:<br />

PO-363:<br />

Silencing <strong>of</strong> PKG1 Gene Sensitizes Vascular Smooth<br />

Muscle Cells to Marinobufagenin: Impact on Aging,<br />

Fibrosis, and Salt-Sensitivity<br />

Olga V. Fedorova, 1 Victoria Y. Shilova, 1 Joseph I.<br />

Shapiro, 2 Edward G. Lakatta, 1 Alexei Y. Bagrov. 1<br />

1 Intramural Research <strong>Program</strong>, National Institute on<br />

Aging, NIH, Baltimore, MD, US; 2 College <strong>of</strong> Medicine,<br />

University <strong>of</strong> Toledo, Toledo, OH, US.<br />

Heritability <strong>of</strong> Na/K Excretion during the Saline/<br />

Lasix Protocol in African <strong>American</strong> Twins<br />

Clarence E. Grim, Robinson Miguel. High Blood<br />

Pressure Consulting, Milwaukee, WI, US.<br />

142


Monday Morning Afternoon MAY 21 23<br />

Posters<br />

PO-364:<br />

Gender Difference in the Relationship <strong>of</strong><br />

Marinobufagein to Salt-Sensitivity <strong>of</strong> Blood Pressure<br />

Alexei Y. Bagrov, 1 Olga V. Fedorova, 1 Philippe Burri, 2<br />

Edward G. Lakatta, 1 Olle Melander. 2 1 National Institute<br />

on Aging, NIH, Baltimore, MD, US; 2 Lund University,<br />

Malmö, SE.<br />

Secondary <strong>Hypertension</strong><br />

PO-365:<br />

PO-366:<br />

PO-367:<br />

Association <strong>of</strong> Renal Artery Stenosis with Acute<br />

Pulmonary Edema in Hypertensive Patients<br />

Roxana O. Darabont, 1 Alexandru Corlan, 2 Mircea<br />

Cinteza, 1 Dragos Vinereanu. 1 1 University <strong>of</strong> Medicine<br />

and Pharmacy ‘Carol Davila’, Bucharest, RO;<br />

2 University Emergency Hospital, Bucharest, RO.<br />

Big Endothelin-1 and Nitric Oxid Levels in<br />

Hypertensive Elderly with and without Obstructive<br />

Sleep Apnea<br />

Nereida K. C. Lima, Iara F. Anunciato, Romulo R.<br />

Lobo, Alan L. Eckeli, Regina M. R. Fernandes, Paulo<br />

R. B. Evora, Fernando Nobre, Waldiceu A. Verri-<br />

Junior, Julio C. Moriguti, Eduardo Ferriolli, Eduardo B.<br />

Coelho. Ribeirao Preto School <strong>of</strong> Medicine – Sao Paulo<br />

University, Ribeirao Preto, SP, BR.<br />

Pheochromocytoma and Coronary Artery Disease<br />

Galina N. Potapova, 1 L. M. Sergakova, 1 G. V.<br />

Ryabikina, 1 L. N. Lyutikova, 1 I. E. Chazova, 1 N. S.<br />

Kuznetsov, 2 E. G. Popov, 1 I. Y. Gavrilov. 1 1 Cardiology<br />

Research Complex, Moscow, RU; 2 Endocrinology<br />

Research Center, Moscow, RU.<br />

143


MAY 21 23<br />

Posters Late-Breaking Posters<br />

Monday Afternoon<br />

Morning<br />

LB-PO-01:<br />

LB-PO-02:<br />

LB-PO-03:<br />

ANP-cGMP-PKG Activation Inhibits TGF-b-<br />

Induced Smad3 Nuclear Translocation by Increasing<br />

Smad3 Binding to Cytosolic b2-Tubulin in Rat<br />

Pulmonary Arterial Smooth Muscle Cells<br />

Kaizheng Gong, 1,2 Dongqi Xing, 1 Peng Li, 1<br />

Namasivayam Ambalavanan, 3 Suzanne Oparil, 1 Yiu-<br />

Fai Chen. 1 1 University <strong>of</strong> Alabama at Birmingham,<br />

Birmingham, AL, US; 2 The Second Medical School <strong>of</strong><br />

Yangzhou University, Yangzhou, CN; 3 University <strong>of</strong><br />

Alabama at Birmingham, Birmingham, AL, US.<br />

Effect <strong>of</strong> Carvedilol CR, Lisinopril and Their<br />

Combination on Markers <strong>of</strong> Early Cardiovascular<br />

Disease in Subjects with High-Normal Blood<br />

Pressure: The DETECT Study<br />

Sara M. Saul, 1 Daniel A. Duprez, 1 Wei Zhong, 2<br />

Gregory A. Grandits, 2 Jay N. Cohn. 1 1 University <strong>of</strong><br />

Minnesota Medical School, Minneapolis, MN, US;<br />

2 University <strong>of</strong> Minnesota School <strong>of</strong> Public Health,<br />

Minneapolis, MN, US.<br />

Consistency <strong>of</strong> Masked <strong>Hypertension</strong> in African<br />

<strong>American</strong>s during Repeat Office Visits<br />

Praveen Veerabhadrappa, Keith M. Diaz, Sheara M.<br />

Williamson, Jan Kretzschmar, Deboarh L. Feairheller,<br />

Kathleen M. Sturgeon, Shannon B. Watkins, Michael<br />

D. Brown. Temple University, Philadephia, PA, US.<br />

144


Faculty Disclosure Listing<br />

Rajiv Agarwal, MD<br />

Advisor/Consultant: Abbott, Merck, Daiichi-Sankyo, Reata, Amgen.<br />

Trustee/Board Member/Committee Member: Abbott. Speakers’ Bureau/Speaking/Teaching:<br />

Abbott, Merck.<br />

Lawrence J. Appel, MD, MPH<br />

I have no relationships to disclose.<br />

Donna K. Arnett, PhD, MSPH<br />

I have no relationships to disclose.<br />

Nancy Artinian, RN, BSN<br />

I have no relationships to disclose.<br />

Phyllis August, MD, MPH<br />

Advisor/Consultant: Otsuka.<br />

Abraham Aviv, MD<br />

Employment Income/Salary: University <strong>of</strong> Medicine and Dentistry,<br />

New Jersey Medical School. Grant/Research Support: National Institutes<br />

<strong>of</strong> Health.<br />

George L. Bakris, MD<br />

Advisor/Consultant: Takeda, Abbott, CVRx, Ardian, Walgreen’s,<br />

Johnson & Johnson, Merck. Trustee, Board Member, Committee<br />

Member: National Kidney Foundation. Grant/Research Support:<br />

Forest Labs, Novartis. Speaker’s Bureau/Speaking/Teaching: Forest<br />

Labs, Novartis. President, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Jan N. Basile, MD<br />

Advisor/Consultant: Boehringer-Ingelheim, Forest Laboratories,<br />

Daiichi-Sankyo, Takeda. Speakers’ Bureau/Speaking/Teaching:<br />

Daiichi-Sankyo, Forest, Takeda.<br />

Donald L. Batisky, MD<br />

I have no relationships to disclose.<br />

John D. Bisognano, MD, PhD<br />

Advisor/Consultant: CVRx. Grant/Research Support: CVRx. Secretary,<br />

<strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Henry R. Black, MD<br />

Advisor/Consultant: Servier, Mitsubushi, Xoma, Ligand, Bristol-Myers<br />

Squibb, Biosante, Novartis. Grant/Research Support: AHRQ/HHS.<br />

Speakers’ Bureau/Speaking/Teaching: Daiichi-Sankyo, Boehringer-<br />

Ingelheim, MSD. Immediate Past President, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Michael J. Bloch, MD<br />

Advisor/Consultant: Takeda. Grant/Research Support: Novartis.<br />

Speakers’ Bureau/Speaking/Teaching: AstraZeneca, Abbott, Boehringer-Ingelheim.<br />

Michael W. Brands, PhD<br />

I have no relationships to disclose.<br />

Lynne T. Braun, PhD, CNP<br />

Royalties (Including Trademarks or Patents): UpToDate, Inc. Grant/<br />

Research Support: National Institutes <strong>of</strong> Health. Speakers’ Bureau/<br />

Speaking/Teaching: <strong>American</strong> Heart Association, Spotlight Speaker.<br />

Other Relevant Financial Benefit or Relationship: National Lipid Association<br />

Web Presentation.<br />

Emmanuel Bravo, MD<br />

I have no relationships to disclose.<br />

145


Faculty Disclosure Listing continued<br />

Angela L. Brown, MD<br />

Advisor/Consultant: Takeda. Speakers’ Bureau/Speaking/Teaching:<br />

Novartis, Forest, Pfizer.<br />

Nancy J. Brown, MD<br />

Advisor/Consultant: Novartis, Merck. Grant/Research Support: Forest,<br />

Shire HGT. Ownership/Partnership or Principal <strong>of</strong> Non-Pr<strong>of</strong>it or<br />

for Pr<strong>of</strong>it Corporation: Protein Discovery.<br />

David A. Bushinksy, MD<br />

Employment Income/Salary: Univeristy <strong>of</strong> Rochester. Advisor/Consultant:<br />

Amgen, Genzyme, Relypsa, Cytochroma. Grant/Research<br />

Support: National Institutes <strong>of</strong> Health, Renal Research Institute. Ownership<br />

Interest (Stocks, Excluding Diversified Mutual Funds): Amgen,<br />

Relypsa. Speakers’ Bureau/Speaking/Teaching: Amgen, Genzyme.<br />

Norman R.C. Campbell, MD<br />

Other Relevant Financial Benefit or Relationship: Boehringer-Ingelheim.<br />

Oscar A. Carretero, MD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health, Roche Pharmaceuticals.<br />

Barry L. Carter, PharmD<br />

I have no relationships to disclose.<br />

Alessandro Cataliotti, MD, PhD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health.<br />

John R. Cockcr<strong>of</strong>t, MD<br />

Advisor/Consultant: Forest, Novartis, Genzyme, GlaxoSmithKline.<br />

Grant/Research Support: GlaxoSmithKline. Speakers’ Bureau/Speaking/Teaching:<br />

Genzyme, Amgen.<br />

Jay N. Cohn, MD<br />

I have no relationships to disclose.<br />

Steven D. Crowley, PhD<br />

I have no relationships to disclose.<br />

William C. Cushman, MD<br />

Advisor/Consultant: Takeda, Novartis.<br />

Stephen R. Daniels, MD, PhD<br />

I have no relationships to disclose.<br />

Michael H. Davidson, MD<br />

Advisor/Consultant: Abbott, Aegerion, Amgen, AstraZeneca, Atherotech,<br />

Daiichi-Sankyo, DTC MD, Esperion, GlaxoSmithKline, iMD<br />

(Intelligent Medical Decisions), Kinemed, LipoScience, Merck, Novo<br />

Nordisk, Roche, San<strong>of</strong>i-Aventis, Synarc, Takeda, Vindico Medical<br />

Education. Trustee/Board Member/Committee Member: DTC MD,<br />

Omthera, Pr<strong>of</strong>essional Education, Inc. Medical Education Company,<br />

Sonogene. Grant/Research Support: Abbott, Daiichi-Sankyo, GlaxoSmithKline,<br />

Merck, Roche.<br />

Daniel Duprez, MD, PhD<br />

Advisor/Consultant: Novartis, Abbott, Pfizer, Merck. Grant/Research<br />

Support: Novartis, Roche, Merck. Speakers’ Bureau/Speaking/Teaching:<br />

Novartis, Pfizer, Merck, Boehringer-Ingelheim, Forest, Abbott.<br />

Lance D. Dworkin, MD<br />

Advisor/Consultant: Questcor. Grant/Research Support: Questcor,<br />

Pfizer, AstraZeneca.<br />

146


Faculty Disclosure Listing continued<br />

Brent M. Egan, MD<br />

Advisor/Consultant: NiCox. Grant/Research Support: Daiichi-Sankyo,<br />

Novartis, Takeda.<br />

Paula T. Einhorn, MD, MS<br />

I have no relationships to disclose.<br />

William J. Elliott, MD, PhD<br />

Royalties (Including Trademarks or Patents): Elsevier, Inc. Grant/<br />

Research Support: Forest Research Institute. Speakers’ Bureau/Speaking/Teaching:<br />

Forest Laboratories, Boehringer-Ingelheim, NiCox,<br />

Inc., <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>.<br />

Murray Epstein, MD<br />

Advisor/Consultant: Bristol-Myers Squibb, AstraZeneca.<br />

Murray D. Esler, MBBS, PhD<br />

Advisor/Consultant: ADRIAN Corporation, Chief Investigator International<br />

Trial. Speakers’ Bureau/Speaking/Teaching: Solvay Australia.<br />

Bonita Falkner, MD<br />

Advisor/Consultant: AstraZeneca, Pfizer, Merck.<br />

Sadaf Farooqi, PhD<br />

I have no relationships to disclose.<br />

Daniel I. Feig, MD, PhD<br />

I have no relationships to disclose.<br />

Ross Feldman, MD<br />

Advisor/Consultant: AstraZeneca, Boehringer-Ingelheim, Bristol-<br />

Myers Squibb, Merck, Forest Canada, Novartis, Pfizer, San<strong>of</strong>i-Aventis,<br />

Servier, Takeda. Trustee/Board Member/Committee Member: Servier,<br />

Takeda.<br />

Keith C. Ferdinand, MD<br />

Advisor/Consultant: AstraZeneca, Merck, Pfizer, Novartis, Takeda,<br />

Forest. Grant/Research Support: Daiichi-Sankyo. Speakers’ Bureau/<br />

Speaking/Teaching: Novartis, AstraZeneca. Member, <strong>ASH</strong> Board <strong>of</strong><br />

Directors.<br />

John M. Flack, MD, MPH<br />

Advisor/Consultant: Novartis, Daiichi-Sankyo. Grant Research/<br />

Support: Novartis. Speakers’ Bureau/Speaking/Teaching: Novartis,<br />

Daiichi-Sankyo, Boehringer-Ingelheim.<br />

Joseph T. Flynn, MD<br />

Advisor/Consultant: Pfizer, Novartis, PTC Therapeutics.<br />

Stanley S. Franklin, MD<br />

I have no relationships to disclose.<br />

William H. Frishman, MD<br />

Ownership Interest (Stocks, Excluding Diversified Mutual Funds):<br />

Merck, Pfizer. Speakers’ Bureau/Speaking/Teaching: NCME (Bristol-<br />

Myers Squibb), Pfizer, Forest Laboratories, Boehringer-Ingelheim.<br />

James B. Froehlich, MD, MPH<br />

Advisor/Consultant: Merck, San<strong>of</strong>i-Aventis. Speakers’ Bureau/Speaking/Teaching:<br />

Merck, Schering-Plough.<br />

Leonard M. Fromer, MD<br />

Trustee/Board Member/Committee Member: TransferMed, LLC.<br />

Jeffrey L. Garvin, PhD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health.<br />

147


Faculty Disclosure Listing continued<br />

Haralambos Gavras, MD<br />

Advisor/Consultant: Medivation, Merck. Speakers’ Bureau/Speaking/<br />

Teaching: Novartis.<br />

F. Wilford Germino, MD<br />

I have no relationships to disclose.<br />

Thomas D. Giles, MD<br />

Advisor/Consultant: Amylin, Forest, NiCox. Grant/Research Support:<br />

Forest. Speakers’ Bureau/Speaking/Teaching: Forest. Member, <strong>ASH</strong><br />

Board <strong>of</strong> Directors. Chair, <strong>ASH</strong> Specialists <strong>Program</strong> Inc.<br />

Alan H. Gradman, MD<br />

Advisor/Consultant: Novartis, Forest, Takeda, Daiichi-Sankyo. Speakers’<br />

Bureau/Speaking/Teaching: Novartis, Forest, Takeda. Member,<br />

<strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Joey P. Granger, PhD<br />

I have no relationships to disclose.<br />

Richard H. Grimm, MD, PhD<br />

Advisor/Consultant: Abbott. Grant/Research Support: Roche. Speakers’<br />

Bureau/Speaking/Teaching: Merck.<br />

Yuan Guo, MD, MS<br />

I have no relationships to disclose.<br />

John E. Hall, PhD<br />

I have no relationships to disclose.<br />

Joel Handler, MD<br />

I have no relationships to disclose.<br />

David Harder, MD, PhD<br />

I have no relationships to disclose.<br />

Raymond C. Harris, MD<br />

I have no relationships to disclose.<br />

David G. Harrison, MD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health.<br />

Joseph A. Hill, MD<br />

I have no relationships to disclose.<br />

Norman K. Hollenberg, MD, PhD<br />

Advisor/Consultant: Novartis, Merck, Vitae Pharmaceuticals. Grant/<br />

Research Support: Vitae Pharmaceuticals.<br />

Suzanne Hughes, MSN, RN<br />

I have no relationships to disclose.<br />

Joseph L. Izzo, Jr., MD<br />

Advisor/Consultant: Pharmacists Mutural, Boehringer-Ingelheim,<br />

Novartis, Curry Rockfeller, Thornton Medical, Daiichi-Sankyo, SCS<br />

Healthcare, Takeda, Maritz Travel Co. Grant/Research Support:<br />

Novartis, Daiichi-Sankyo. Speakers’ Bureau/Speaking/Teaching: Novartis,<br />

Daiichi-Sankyo, SCS Healthcare, Maritz Travel Co.<br />

Edgar A. Jaimes, MD<br />

Advisor/Consultant: Novartis.<br />

148


Faculty Disclosure Listing continued<br />

Kenneth A. Jamerson, MD<br />

Advisor/Consultant: Boehringer-Ingelheim, Eli Lily, Daiichi-Sankyo,<br />

Novartis. Trustee/Board Member/Committee Member: <strong>American</strong><br />

<strong>Society</strong> Of <strong>Hypertension</strong>, International <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong><br />

in Blacks. Grant/Research Support: National Institutes <strong>of</strong> Health,<br />

National Institute <strong>of</strong> Diabetes and Digestive and Kidney Diseases, National<br />

Heart, Lung, and Blood Institute, Novartis. Speakers’ Bureau/<br />

Speaking/Teaching: Daiichi-Sankyo.<br />

Julie A. Johnson, PharmD<br />

Advisor/Consultant: Medco.<br />

Richard J. Johnson, MD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health. Other Relevant<br />

Financial Benefit or Relationship: Patent on the Use <strong>of</strong> Allopurinol to<br />

Treat <strong>Hypertension</strong>.<br />

Pedro A. Jose, MD<br />

Grant/Research Support: National Heart, Lung, and Blood Institute,<br />

National Institutes <strong>of</strong> Health, National Institute <strong>of</strong> Diabetes and<br />

Digestive and Kidney Diseases, BIAL. Ownership/Partnership or<br />

Principal <strong>of</strong> Non-Pr<strong>of</strong>it or for Pr<strong>of</strong>it Corporation: Hypogen, Inc.<br />

Luis I. Juncos, MD<br />

I have no relationships to disclose.<br />

Rae‐Ellen W. Kavey, MD, MPH<br />

I have no relationships to disclose.<br />

Donald E. Kohan, MD, PhD<br />

Advisor/Consultant: Abbott, Pfizer, Gilead, Bristol-Myers Squibb.<br />

Grant/Research Support: National Institutes <strong>of</strong> Health. VA, Gilead.<br />

David S. Kountz, MD<br />

I have no relationships to disclose.<br />

Lawrence R. Krak<strong>of</strong>f, MD<br />

I have no relationships to disclose.<br />

Henry Krum, MBBS<br />

Grant/Research Support: Ardian.<br />

Louis Kuritzky, MD<br />

Advisor/Consultant: Boehringer-Ingelheim, Takeda. Speakers’ Bureau/Speaking/Teaching:<br />

Boehringer-Ingelheim, Takeda.<br />

Theodore W. Kurtz, MD<br />

I have no relationships to disclose.<br />

Robert F. Kushner, MD<br />

I have no relationships to disclose.<br />

Daniel T. Lackland, DrPH<br />

Speakers’ Bureau/Speaking/Teaching: San<strong>of</strong>i-Aventis, Boehringer-<br />

Ingelheim. Member, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Edward G. Lakatta, MD<br />

I have no relationships to disclose.<br />

Babbette LaMarca, PhD<br />

Grant/Research Support: <strong>American</strong> Heart Association, National<br />

Institutes <strong>of</strong> Health.<br />

Marc B. Lande, MD, MPH<br />

Grant/Research Support: National Institutes <strong>of</strong> Health.<br />

149


Faculty Disclosure Listing continued<br />

Daniel Levy, MD<br />

Member, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Nita A. Lindi, PharmD, PhD, MSPH<br />

I have no relationships to disclose.<br />

Tianh Liu, MD<br />

Employment Income/Salary: Pi County People’s Hospital.<br />

Charles J. Lowenstein, MD<br />

I have no relationships to disclose.<br />

Jianfang Luo, MD<br />

I have no relationships to disclose.<br />

James M. Luther, MD<br />

I have no relationships to disclose.<br />

Giuseppe Mancia, MD<br />

Advisor/Consultant: Bayer, Boehringer-Ingelheim, MSD, Menaribni<br />

International, Novartis, Recordati, San<strong>of</strong>i-Aventis, Servier. Grant/<br />

Research Support: Gilead, Servier.<br />

Samuel J. Mann, MD<br />

Grant/Research Support: Forest. Speaker’s Bureau/Speaking/Teaching:<br />

Forest.<br />

Athanasios J. Manolis, MD, PhD<br />

Advisor/Consultant: Menarini, Abbott. Speakers’ Bureau/Speaking/<br />

Teaching: Menarini, Recordati.<br />

Allyn L. Mark, MD<br />

I have no relationships to disclose.<br />

Barry J. Materson, MD, MBA<br />

Grant/Research Support: Forest, Takeda, Merck.<br />

David L. Mattson, PhD<br />

I have no relationships to disclose.<br />

Richard J. McManus, MD<br />

Grant/Research Support: Omron Europe (potential).<br />

John Merenich, MD<br />

I have no relationships to disclose.<br />

Franz H. Messerli, MD<br />

Advisor/Consultant: Novartis, Daiichi-Sankyo, San<strong>of</strong>i-Aventis,<br />

Takeda, Abbott. Grant/Research Support: Forest, Daiichi-Sankyo,<br />

Boehringer-Ingelheim. Treasurer, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Nancy Houston Miller, RN, BSN<br />

Advisor/Consultant: Abbott, Gilead, Novartis.<br />

Mark E. Molitch, MD<br />

Advisor/Consultant: Novartis, Abbott. Grant/Research Support: Eli<br />

Lily.<br />

Krzyszt<strong>of</strong> Narkiewicz, MD, PhD<br />

Speakers’ Bureau/Speaking/Teaching: Berlin Chernie Menarini,<br />

Boehringer-Ingelheim, Daiichi-Sankyo, Krka, Novartis, Servier.<br />

150


Faculty Disclosure Listing continued<br />

L. Gabriel Navar, PhD<br />

Advisor/Consultant: Forest, Novartis, Nicor, Merck & Co., Boehringer-Ingelheim.<br />

Trustee/Board Member/Committee Member: <strong>American</strong><br />

Heart Association, <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inter<strong>American</strong><br />

<strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>. Grant/Research Support: National Heart,<br />

Lung and Blood Institute, NCRR, Merck, Forest. Ownership Interest<br />

(Stocks, Excluding Diversified Mutual Funds): Abbott, AstraZeneca,<br />

Baxter International, Merck & Co., Pfizer, Inc. Speakers’ Bureua/<br />

Speaking/Teaching: Merck & Co., Forest Pharmaceuticals.<br />

Shawna D. Nesbitt, MD, MS<br />

Advisor/Consultant: Daiichi-Sankyo. Speakers’ Bureau/Speaking/<br />

Teaching: Novartis, Gilead, Boehringer-Ingelheim.<br />

Joel M. Neutel, MD<br />

Speakers’ Bureau/Speaking/Teaching: Novartis, Forest, Bristol-Myers<br />

Squibb – San<strong>of</strong>i-Aventis, Takeda, Boehringer-Ingelheim, Daiichi-<br />

Sankyo.<br />

Susanne B. Nicholas, MD, PhD, MPH<br />

I have no relationships to disclose.<br />

Eoin O’Brien, MD<br />

I have no relationships to disclose.<br />

Gbenga Ogedegbe, MD, MPH, MS<br />

I have no relationships to disclose.<br />

Suzanne Oparil, MD<br />

Advisor/Consultant: Boehringer-Ingelheim, Daiichi-Sankyo, Eli Lily,<br />

Forest, NiCox, Novartis, Omron. Grant/Research Support: Amgen,<br />

Inc., Merck & Co. Speakers’ Bureau/Speaking/Teaching: Daiichi-<br />

Sankyo, Novartis, Pfizer.<br />

Julio A. Panza, MD<br />

I have no relationships to disclose.<br />

Vasilios Papademetriou, MD<br />

I have no relationships to disclose.<br />

Thomas A. Pearson, MD, PhD, MPH<br />

I have no relationships to disclose.<br />

Aldo J. Peixoto, MD<br />

I have no relationships to disclose.<br />

Robert A. Phillips, MD, PhD<br />

Member, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

F. Xavier Pi‐Sunyer, MD, MPH<br />

Advisor/Consultant: Novo Nordisk, AstraZeneca. Grant/Research<br />

Support: Novo Nordisk.<br />

Bertram Pitt, MD<br />

Advisor/Consultant: Relypsa. Ownership Interest (Stocks, Excluding<br />

Diversified Mutual Funds): Relypsa, BG-Medicine, Nile Therapeutics.<br />

Velvie A. Pogue, MD<br />

Employment Income/Salary: Columbia University Affiliation at the<br />

Harlem Hospital Center. Grant/Research Support: Amgen.<br />

David M. Pollock, PhD<br />

Advisor/Consultant: Abbott Laboratories.<br />

Howard J. Pratt, MD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health.<br />

151


Faculty Disclosure Listing continued<br />

Henry A. Punzi, MD<br />

Advisor/Consultant: Daiichi-Sankyo, Boehringer-Ingelheim, Forest<br />

Pharamaceuticals. Grant/Research Support: Daiichi-Sankyo, Boehringer-Ingelheim,<br />

Forest Pharmaceuticals, Abbott. Speakers’ Bureau/<br />

Speaking/Teaching: Daiichi-Sankyo, Boehringer-Ingelheim, Forest<br />

Pharmaceuticals, Abbott.<br />

Leopoldo Raij, MD<br />

I have no relationships to disclose.<br />

C. Venkata S. Ram, MD<br />

Advisor/Consultant: Daiichi-Sankyo, Forest. Speakers’ Bureau/Speaking/Teaching:<br />

Peer Group Med Knowledge.<br />

James Rippe, MD<br />

Advisor/Consultant: ConAgra Foods, Corn Refiners Association.<br />

Grant/Research Support: ConAgra Foods, Corn Refiners Association.<br />

Talma Rosenthal, MD<br />

Royalties (Including Trademarks or Patents): Patent (2%) Allyl<br />

Mercaptocptopril), Weitzmann Institute. Trustee/Board Member/<br />

Committee Member: Tel-Aviv University Sackler School <strong>of</strong> Medicine.<br />

Grant/Research Support: Boehringer-Ingelheim. Speakers’ Bureau/<br />

Speaking/Teaching: Tel-Aviv University Sackler School <strong>of</strong> Medicine.<br />

Luis M. Ruilope, MD<br />

Advisor/Consultant: AstraZeneca, Novartis, Bayer, Servier, Daiichi-<br />

Sankyo, Takeda, Pfizer, Otsuka. Menarini, Bayer. Speakers’ Bureau/<br />

Speaking/Teaching: AstraZeneca, Novartis, Bayer, Servier, Daiichi-<br />

Sankyo, Takeda, Pfizer, Otsuka. Menarini, Bayer.<br />

Michael J. Ryan, PhD<br />

Grant/Research Support: National Institutes <strong>of</strong> Health/ National<br />

Heart, Lung and Blood Institute.<br />

Elijah Saunders, MD<br />

Advisor/Consultant: Pfizer, Novartis, Forest, Bristol-Myers Squibb-<br />

San<strong>of</strong>i-Aventis, Boehringer-Ingelheim, Bristol-Myers Squibb, Eli<br />

Lilly. Grant/Research Support: Pfizer, Novartis, Forest, Bristol-Myers<br />

Squibb-San<strong>of</strong>i-Aventis. Speakers’ Bureau/Speaking/Teaching: Pfizer,<br />

Novartis, Forest, Bristol-Myers Squibb-San<strong>of</strong>i-Aventis, Boehringer-<br />

Ingelheim, Bristol-Myers Squibb, Eli Lilly.<br />

Ernesto L. Schiffrin, MD, PhD<br />

I have no relationships to disclose.<br />

Roland E. Schmieder, MD<br />

Grant/Research Support: Ardian.<br />

Antoinette Schoenthaler, EdD<br />

Advisor/Consultant: Harlem Hospital Stroke Center.<br />

Domenic A. Sica, MD<br />

Advisor/Consultant: Novartis, Takeda, Merck, Boehringer-Ingelheim,<br />

CVRx. Grant/Research Support: CVRx. Speakers’ Bureau/Speaking/<br />

Teaching: Takeda.<br />

Matthew Sorrentino, MD<br />

I have no relationships to disclose.<br />

Thomas A. Sos, MD<br />

Royalties (Including Trademarks or Patents): AngioDynamics, Cook<br />

Medical.<br />

152


Faculty Disclosure Listing continued<br />

James R. Sowers, MD<br />

Advisor/Consultant: Novartis Pharmaceuticals. Grant/Research Support:<br />

National Institutes <strong>of</strong> Health, VA Merit.<br />

Lesley A. Stevens, MD, MS<br />

I have no relationships to disclose.<br />

Allan D. Struthers, MD<br />

Royalties (Including Trademarks or Patents): Filed a patent on the<br />

use <strong>of</strong> xanthine oxidate inhibitors in angina.<br />

Laura P. Svetkey, MD<br />

I have no relationships to disclose.<br />

Sandra J. Taler, MD<br />

Vice President, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Ting Tao, MD<br />

I have no relationships to disclose.<br />

Addison A. Taylor, MD, PhD<br />

Employment Income/Salary: Baylor College <strong>of</strong> Medicine. Advisor/<br />

Consultant: National Association <strong>of</strong> Managed Care Physicians. Grant/<br />

Research Support: Bristol-Myers Squibb, Novartis, National Institues<br />

<strong>of</strong> Health. Speakers’ Bureau/Speaking/Teaching: Forest Pharmaceuticals,<br />

Novartis, The Methodist Hospital, University <strong>of</strong> Texas. Member,<br />

<strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Jens Titze, MD<br />

I have no relationships to disclose.<br />

Sheldon W. Tobe, MD<br />

Advisor/Consultant: Pfizer, Bristol-Myers Squibb, Merck, Abbott.<br />

Grant/Research Support: Pfizer, Novartis, Amgen. Speakers’ Bureau/<br />

Speaking/Teaching: Abbott,<br />

Bristol-Myers Squibb, Pfizer, Merck.<br />

Rhian M. Touyz, MD, PhD<br />

I have no relationships to disclose.<br />

Raymond R. Townsend, MD<br />

Royalties (Including Trademarks or Patents): UptoDate. Advisor/Consultant:<br />

GlaxoSmithKline, Merck, Novartis. Grant/Research Support:<br />

National Institutes <strong>of</strong> Health.<br />

Joseph A. Vassalotti, MD<br />

I have no relationships to disclose.<br />

Ronald G. Victor, MD<br />

Advisor/Consultant: Merck Research Laboratories. Grant/Research<br />

Support: Pfizer, Forest Research Laboratories.<br />

Hongyu Wang, MD, PhD<br />

I have no relationships to disclose.<br />

R. Clinton Webb, PhD<br />

I have no relationships to disclose.<br />

David J. Webb, MD<br />

Advisor/Consultant: Abbott, Pfizer. Grant/Research Support: Pfizer.<br />

Michael A. Weber, MD<br />

Advisor/Consultant: Bristol-Myers Squibb, Boehringer-Ingelheim,<br />

Takeda, Novartis, Daiichi-Sankyo. Trustee/Board Member/Committee<br />

Member: Center for Medicine in the Public Interest. Member,<br />

<strong>ASH</strong> Board <strong>of</strong> Directors. Editor-In-Chief, The Journal <strong>of</strong> Clinical<br />

<strong>Hypertension</strong> (JCH).<br />

153


Faculty Disclosure Listing continued<br />

Alan B. Weder, MD<br />

I have no relationships to disclose.<br />

Myron H. Weinberger, MD<br />

Employment Income/Salary: <strong>American</strong> <strong>Society</strong> Of <strong>Hypertension</strong><br />

(Editor-in-Chief, Journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong><br />

(J<strong>ASH</strong>)). Member, <strong>ASH</strong> Board <strong>of</strong> Directors.<br />

Matthew R. Weir, MD<br />

Advisor/Consultant: Amgen, Daiichi-Sankyo. Member, <strong>ASH</strong> Board <strong>of</strong><br />

Directors.<br />

Adam Whaley‐Connell, DO<br />

I have no relationships to disclose.<br />

Andrew Whelton, MD<br />

Advisor/Consultant: Takeda. Speakers’ Bureau/Speaking/Teaching:<br />

Takeda.<br />

William B. White, MD<br />

Advisor/Consultant: Astellas, Forest, Novartis, Roche, Teva, Takeda.<br />

Grant/Research Support: Novartis. Other Relevant Financial Benefit<br />

or Relationship: Pfizer, Inc., DMC Consultant. President-Elect <strong>ASH</strong><br />

Board <strong>of</strong> Directors. <strong>ASH</strong> Scientific <strong>Program</strong> Committee Chair.<br />

Ian B. Wilkinson, MD<br />

Advisor/Consultant: GlaxoSmithKline, MSD. Grant/Research Support:<br />

GlaxoSmithKline.<br />

Bryan Williams, MD<br />

I have no relationships to disclose.<br />

Gordon H. Williams, MD<br />

I have no relationships to disclose.<br />

Peter F. Wilson, MD<br />

I have no relationships to disclose.<br />

Nathan D. Wong<br />

Advisor/Consultant: Abbott. Grant/Research Support: Merck, Bristol-<br />

Myers Squibb.<br />

Martin S. Zand, MD<br />

I have no relationships to disclose.<br />

154


<strong>ASH</strong> <strong>Hypertension</strong> Resource Pavilion<br />

Hilton New York • Americas Hall I • Third Floor<br />

Innovations Theater<br />

Americas Hall I<br />

(Third Floor)<br />

<strong>ASH</strong> Posters<br />

(Second Floor Promenade)<br />

<strong>ASH</strong><br />

Outreach<br />

Innovations Theater<br />

1600<br />

Takeda<br />

Pharmaceuticals<br />

North <strong>American</strong> Inc.<br />

1400<br />

1600<br />

<strong>ASH</strong><br />

Outreach<br />

TO AMERICAS HALL II<br />

ESCALATOR<br />

UP<br />

Daiichi Sankyo Inc.<br />

1200<br />

Novartis<br />

Pharmaceuticals<br />

1100<br />

Takeda<br />

Pharmaceuticals<br />

North <strong>American</strong> Inc.<br />

Wiley-Blackwell<br />

1400<br />

1202 1204<br />

Mortara<br />

HoMedics<br />

1105 1107<br />

Daiichi David Sankyo Inc. ISHIB<br />

Lerner<br />

1200<br />

1102 1103<br />

Elsevier Inc.<br />

AtCor Medical, Inc.<br />

1106<br />

Wiley-Blackwell<br />

1202 1204<br />

1104<br />

Mortara<br />

HoMedics<br />

Elsevier Inc.<br />

Ajinomoto<br />

AtCor Medical, Inc.<br />

Omron Healthcare Novartis Forest Lippincott 1105 1107 A & D<br />

SunTech<br />

Medical<br />

Medical<br />

Novartis<br />

David ISHIB<br />

1106<br />

1000 Pharmaceuticals 1004 1006 1008 Lerner 1010 1014<br />

1100<br />

1102 1103<br />

1104<br />

Ajinomoto<br />

National<br />

Kidney<br />

1206<br />

Woman<br />

Heart<br />

1110<br />

National<br />

Kidney<br />

1206<br />

Woman<br />

Heart<br />

1110<br />

ENTRANCE<br />

Omron Healthcare Novartis Forest Lippincott A & D<br />

Medical<br />

SunTech<br />

Medical<br />

1000 1004 1006 1008 1010 1014<br />

TED FIRE ALARMS<br />

TED FIRE EXITS<br />

155


<strong>ASH</strong> Exposition Guide<br />

Hilton New York • Americas Hall I • Third Floor<br />

Hours:<br />

Saturday, May 21, 4:30 PM – 7:30 PM<br />

Sunday, May 22, 10:00 AM – 1:00 PM, 3:30 PM – 6:30 PM<br />

Monday, May 23, 10:00 AM – 1:30 PM, 4:00 PM – 5:30 PM<br />

<strong>ASH</strong> <strong>Hypertension</strong> Resource Pavilion<br />

America’s Hall I – Third Floor<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong> Community<br />

Outreach<br />

Booth Number: 1600<br />

Controlling your blood pressure is a<br />

check away!<br />

Get your blood pressure checked<br />

today at our Outreach Booth!!<br />

In <strong>2011</strong>, we are proud to continue<br />

with our Fourth Annual <strong>Hypertension</strong><br />

Community Outreach <strong>Program</strong> in the<br />

Greater New York City area, Northern<br />

New Jersey, and Long Island, NY.<br />

View videos and photos <strong>of</strong> all <strong>of</strong> our<br />

past Outreach <strong>Program</strong>s from New<br />

Orleans (2008), San Francisco (2009),<br />

and New York (2010). Our recently<br />

released educational videos will also<br />

be on view. The <strong>ASH</strong> published “Blood<br />

Pressure and Your Health” patient<br />

information pamphlets are available<br />

here as well.<br />

Check it out!!—go to Times Square—<br />

42nd Street between 7th and 8th Avenues<br />

and look up at the CBS “Super<br />

Screen” and you will see the new <strong>ASH</strong><br />

Public Service Announcement shown<br />

18 times a day.<br />

A & D Medical<br />

Booth Number: 1010<br />

A&D Medical / LifeSource manufacturers<br />

blood pressure monitors and<br />

other home health care products for<br />

home and pr<strong>of</strong>essional use. Models include<br />

automatic, manual, ambulatory,<br />

kiosk style and accessories including<br />

stethoscopes.<br />

A&D Medical is a division <strong>of</strong> A&D<br />

Engineering, and is ISO 13485:2003<br />

certified. Since 1977, A&D Medical<br />

has manufactured and distributed a<br />

full line <strong>of</strong> advanced electronic blood<br />

pressure monitoring equipment and<br />

health care products for home and<br />

pr<strong>of</strong>essional use. The company has<br />

established itself as a leader in home<br />

health monitoring technology through<br />

the development and introduction<br />

<strong>of</strong> a variety <strong>of</strong> unique products.<br />

A&D’s LifeSource® blood pressure<br />

monitor line has garnered numerous<br />

industry awards. Recent product<br />

introductions include: the LifeSource®<br />

digital thermometers, personal scales,<br />

stethoscopes, and Ambulatory Blood<br />

Pressure Monitors.<br />

Ajinomoto USA, Inc.<br />

Booth Number: 1104<br />

Since 1909, Ajinomoto Co., a leader<br />

in the development <strong>of</strong> pharmaceutical<br />

quality amino acids and distributor<br />

<strong>of</strong> products that <strong>of</strong>fer a holistic,<br />

side-effect free solution to today’s top<br />

health concerns <strong>of</strong> weight management,<br />

sleep quality improvement and<br />

healthy blood pressure management.<br />

These products are Capsiate Natura®,<br />

a patented, side effect-free dietary<br />

supplement with natural capsinoids<br />

shown to boost the body’s metabolism;<br />

Glysom, a safe, effective and<br />

scientifically-proven amino acid-based<br />

solution for deeper, sounder and<br />

more satisfying sleep, and Natura<br />

Guard BP, a milk protein-derived<br />

nutraceutical to help maintain healthy<br />

blood pressure levels already within<br />

the normal range.<br />

For more information, visit<br />

www.capsiatenatura.com,<br />

www.glysom.com and<br />

www.naturaguardbp.com<br />

AtCor Medical, Inc. (USA)<br />

Booth Number: 1106<br />

AtCor Medical developed and markets<br />

SphygmoCor® systems, the global gold<br />

standard in noninvasive assessment<br />

<strong>of</strong> central blood pressure and arterial<br />

stiffness. Featured in over 600 published<br />

studies, SphygmoCor systems<br />

are used worldwide in leading medical<br />

centers, physicians’ <strong>of</strong>fices, in research<br />

and in pharmaceutical clinical trials.<br />

Daiichi Sankyo, Inc.<br />

Booth Number: 1200<br />

Daiichi Sankyo, Inc. (DSI), headquartered<br />

in Parsippany, NJ, is the<br />

U. S. subsidiary <strong>of</strong> Daiichi Sankyo<br />

Co., Ltd., a global pharmaceutical<br />

company. DSI was formed in 2006<br />

from the integration <strong>of</strong> two leading<br />

pharmaceutical companies, Sankyo<br />

Pharma, Inc. and Daiichi Pharmaceutical<br />

Corporation. Its team <strong>of</strong> nearly<br />

3,000 U.S. employees is dedicated to<br />

the creation and supply <strong>of</strong> innovative<br />

pharmaceutical products to address<br />

the diversified, unmet medical needs<br />

<strong>of</strong> patients. DSI concentrates in the<br />

therapy areas <strong>of</strong> hypertension, thrombosis,<br />

dyslipidemia, diabetes and<br />

acute coronary syndrome. Clinical<br />

development and regulatory activities<br />

are headquartered at Daiichi Sankyo<br />

Pharma Development in Edison, NJ.<br />

Visit www.dsi.com.<br />

David Lerner Associates<br />

Booth Number: 1102<br />

Financial Investments at David Lerner<br />

Associates<br />

We believe gambling and investing are<br />

not the same.<br />

We believe the stock market should make<br />

for interesting dinner conversation but<br />

should not be a matter <strong>of</strong> financial life<br />

or death.<br />

We believe we have an obligation to<br />

guide our investors in directions we feel<br />

will help them achieve their financial<br />

objectives.<br />

We believe investors should not be chasing<br />

financial rainbows.<br />

We do not run with the herd. We pursue<br />

these fundamental investment principles<br />

regardless <strong>of</strong> market conditions.<br />

While <strong>of</strong>fering a full range <strong>of</strong> investments,<br />

we feature those that we believe<br />

are based on real value and regularly pay<br />

dividends or interest.<br />

Elsevier<br />

Booth Number: 1204<br />

ELSEVIER, a premier worldwide health<br />

science publishing company, is proud<br />

to publish Journal <strong>of</strong> the AMERICAN<br />

SOCIETY OF HYPERTENSION, the<br />

<strong>of</strong>ficial journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>. Please stop by our booth<br />

to view the latest issue <strong>of</strong> the journal.<br />

Forest Pharmaceuticals, Inc.<br />

Booth Number: 1006<br />

Forest Pharmaceuticals, Inc welcomes<br />

you to New York! We invite you to visit<br />

our exhibit. Please visit our website at<br />

www.forestpharm.com<br />

Community Partner <strong>of</strong> the <strong>ASH</strong><br />

<strong>Hypertension</strong> Community Outreach<br />

<strong>Program</strong><br />

HoMedics<br />

Booth Number: 1107<br />

Since HoMedics was founded in 1987,<br />

they have become the #1 name in health<br />

and wellness with an extensive line <strong>of</strong><br />

products that allow you to take a proactive<br />

role in managing your health.<br />

HoMedics blood pressure monitors are<br />

clinically proven accurate and <strong>of</strong>fer a<br />

wide range <strong>of</strong> innovative features and<br />

technologies that make monitoring your<br />

blood pressure at home easier than ever.<br />

Select arm and wrist models <strong>of</strong>fer Voice<br />

Assist® Talking Function, Supersize<br />

Digits®, Risk Category Index, Easy One<br />

Button Operation, Dual User Memory<br />

and 2 cuffs to fit most arm sizes.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong><br />

<strong>Hypertension</strong> Community Outreach<br />

<strong>Program</strong><br />

International <strong>Society</strong> on<br />

<strong>Hypertension</strong> in Blacks, Inc. (ISHIB)<br />

Booth Number: 1103<br />

Founded in 1986, ISHIB is a non-pr<strong>of</strong>it<br />

organization <strong>of</strong> healthcare pr<strong>of</strong>essions<br />

and leaders in cardiovascular disease<br />

and related disorders. Our mission is to<br />

improve the health and life expectancy <strong>of</strong><br />

ethnic minorities and eliminate racial and<br />

ethnic health disparities in cardiovascular<br />

disease through pr<strong>of</strong>essional and public<br />

education, targeted clinical research, and<br />

facilitation <strong>of</strong> the delivery <strong>of</strong> higher quality<br />

cardiovascular health care. We host<br />

an annual conference, membership and<br />

other programs.<br />

Lippincott, Williams & Wilkins, a<br />

Wolters Kluwer Health Company<br />

Booth Number: 1008<br />

Lippincott Williams & Wilkins, Wolters<br />

Kluwer Health Company, is the proud<br />

publisher <strong>of</strong> <strong>Hypertension</strong>, Journal <strong>of</strong><br />

the <strong>American</strong> Heart Association, and<br />

the Journal <strong>of</strong> <strong>Hypertension</strong>, Official<br />

Journal <strong>of</strong> the International <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong> and the European <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong>. We <strong>of</strong>fer a full range<br />

<strong>of</strong> specialized books, journals, and electronic<br />

media. Visit us today!<br />

Mortara Instrument<br />

Booth Number: 1105<br />

Mortara Instrument is proud to <strong>of</strong>fer its<br />

Ambulo 2400 ambulatory blood pressure<br />

(ABPM) technology at the <strong>American</strong><br />

<strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>’s <strong>2011</strong> Annual<br />

Scientific Meeting and Exposition. Designed<br />

and made in the USA, the Ambulo<br />

2400 system allows clinicians, researchers<br />

and other health pr<strong>of</strong>essionals to better<br />

assess a patient’s blood pressure fluctuations<br />

throughout the 24-hour circadian<br />

rhythm.<br />

For over 25 years, Mortara Instrument<br />

has distinguished itself in the field <strong>of</strong><br />

non-invasive cardiology by providing<br />

ECG, Holter and stress systems to customers<br />

worldwide. We are excited to be<br />

adding thorough blood pressure assessment<br />

tools to our portfolio <strong>of</strong> products.<br />

National Kidney Foundation<br />

Booth Number: 1206<br />

NKF <strong>of</strong>fers the nephrology community<br />

the latest science through clinical<br />

practice guidelines, free kidney screening<br />

programs held around the world, and<br />

educational materials for patients and<br />

pr<strong>of</strong>essionals. Learn more about the<br />

soon-to-be published guidelines, including:<br />

KDIGO’s Acute Kidney Injury and<br />

the Update on CKD and Diabetes by<br />

KDOQI. Please visit the booth to signup<br />

to review KDIGO’s Clinical Practice<br />

Guideline on Blood Pressure in CKD.<br />

Novartis Pharmaceuticals<br />

Corporation<br />

Booth Number: 1100, 1004<br />

Novartis Pharmaceuticals is dedicated to<br />

discovering, developing, manufacturing<br />

and marketing prescription drugs that<br />

help meet our customers’ medical needs<br />

and improve their quality <strong>of</strong> life. Please<br />

visit the Novartis exhibit where our sales<br />

representatives will be available to discuss<br />

our products.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong><br />

<strong>Hypertension</strong> Community Outreach<br />

<strong>Program</strong><br />

Omron Healthcare<br />

Booth Number: 1000<br />

Omron Healthcare, Inc., is the leading<br />

manufacturer and distributor <strong>of</strong> blood<br />

pressure monitors for home use. Omron<br />

Healthcare markets clinically proven<br />

products that provide accurate health<br />

information to consumers and physicians<br />

and support position lifestyle changes and<br />

health improvement.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong><br />

<strong>Hypertension</strong> Community Outreach<br />

<strong>Program</strong><br />

SunTech Medical, Inc.<br />

Booth Number: 1014<br />

For over twenty years, SunTech Medical<br />

has been the preeminent supplier <strong>of</strong><br />

clinical grade blood pressure monitoring<br />

products and technologies. SunTech is the<br />

world’s foremost manufacturer <strong>of</strong> ambulatory<br />

blood pressure monitors, including<br />

the Oscar 2 ABPM system, now available<br />

with Pediatric ABPM Interpretation<br />

function, which automatically generates<br />

guidelines specific to analyzing the<br />

24-hour blood pressure data <strong>of</strong> pediatric<br />

patients. Additionally, SunTech <strong>of</strong>fers solutions<br />

for in-<strong>of</strong>fice BP measurement with<br />

the SunTech 247, the first clinical grade<br />

automated blood pressure device to <strong>of</strong>fer<br />

a manual back-up mode, as well as a complete<br />

line <strong>of</strong> blood pressure cuffs. Please<br />

visit our booth for more information.<br />

Takeda Pharmaceuticals North<br />

America, Inc.<br />

Booth Number: 1400<br />

Based in Deerfield, IL. Takeda Pharmaceuticals<br />

North America, Inc. and Takeda<br />

Global Research & Development Center,<br />

Inc. market oral diabetes, insomnia, rheumatology<br />

and gastroenterology treatments<br />

and seek to bring innovative products to<br />

patients through a pipeline that includes<br />

compounds in development for diabetes,<br />

cardiovascular disease, gastroenterology<br />

and neurology. www.tpna.com.<br />

Wiley-Blackwell<br />

Booth Number: 1202<br />

Wiley-Blackwell is the international<br />

scientific, technical, medical and scholarly<br />

publishing business <strong>of</strong> John Wiley & Sons,<br />

with strengths in every major academic<br />

and pr<strong>of</strong>essional field and partnerships<br />

with many <strong>of</strong> the world’s leading societies.<br />

Wiley-Blackwell publishes over 1,400<br />

peer-reviewed journals as well as 1,500+<br />

new books annually in print and online,<br />

as well as databases, major reference<br />

works and laboratory protocols. For more<br />

information, please visit<br />

www.wileyblackwell.com or<br />

http://onlinelibrary.wiley.com/<br />

WomenHeart<br />

Booth Number: 1110<br />

WomenHeart was founded by three<br />

women who had heart attacks while in<br />

their 40s. In addition to being faced with<br />

many obstacles, including misdiagnosis<br />

and social isolation, they were each<br />

amazed how little information about<br />

or services for women with heart<br />

disease were available and how the issue<br />

seemed invisible within the women’s<br />

health community. But in March 1999<br />

everything changed.<br />

156


<strong>2011</strong> <strong>ASH</strong> Innovations Theater<br />

Rhinelander Gallery – 2nd Floor<br />

Saturday, May 21, <strong>2011</strong> • 6:30 PM to 7:30 PM<br />

Daiichi Sankyo, Inc. presents,<br />

The Growing Need for Combination Antihypertensive Therapy<br />

“The Innovations Theater content and the views expressed<br />

therein are those <strong>of</strong> the presenting corporate entity and not <strong>of</strong><br />

the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. The content is not<br />

part <strong>of</strong> the <strong>ASH</strong> Annual Scientific Meeting as approved by the<br />

“Annual Scientific <strong>Program</strong> Committee.”<br />

Sunday, May 22, <strong>2011</strong> • 12:00 PM to 1:00 PM<br />

Takeda Pharmaceuticals, North <strong>American</strong>, Inc. presents,<br />

A Clinical Update in <strong>Hypertension</strong>.<br />

“The Innovations Theater content and the views expressed<br />

therein are those <strong>of</strong> the presenting corporate entity and not <strong>of</strong><br />

the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. The content is not<br />

part <strong>of</strong> the <strong>ASH</strong> Annual Scientific Meeting as approved by the<br />

“Annual Scientific <strong>Program</strong> Committee.”<br />

Sunday, May 22, <strong>2011</strong> • 5:30 PM to 6:30 PM<br />

Novartis Pharmaceuticals Corporation Presentation<br />

“The Innovations Theater content and the views expressed<br />

therein are those <strong>of</strong> the presenting corporate entity and not <strong>of</strong><br />

the <strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>, Inc. The content is not<br />

part <strong>of</strong> the <strong>ASH</strong> Annual Scientific Meeting as approved by the<br />

Annual Scientific <strong>Program</strong> Committee.”<br />

157


<strong>2011</strong> <strong>ASH</strong> Exhibitors<br />

<strong>ASH</strong> <strong>Hypertension</strong> Resource Pavilion • America’s Hall I – 3rd Floor<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong> Community Outreach<br />

Contact: Gilda Caputo-Hansen<br />

148 Madison Ave. 5th Floor<br />

New York, NY 10016<br />

Phone: 212-696-9099<br />

Fax: 212-696-0711<br />

Email: gcaputo@ash-us.org<br />

Website: www.ash-us.org<br />

Booth Number: 1600<br />

Controlling your blood pressure is a check away!<br />

Get your blood pressure checked today at our Outreach<br />

Booth!!<br />

In <strong>2011</strong>, we are proud to continue with our Fourth Annual<br />

<strong>Hypertension</strong> Community Outreach <strong>Program</strong> in the Greater<br />

New York City area, Northern New Jersey, and Long Island,<br />

NY. View videos and photos <strong>of</strong> all <strong>of</strong> our past Outreach<br />

<strong>Program</strong>s from New Orleans (2008), San Francisco (2009), and<br />

New York (2010). Our recently released educational videos will<br />

also be on view. The <strong>ASH</strong> published “Blood Pressure and Your<br />

Health” patient information pamphlets are available here as<br />

well.<br />

Check it out!!—go to Times Square—42nd Street between<br />

7th and 8th Avenues and look up at the CBS “Super Screen”<br />

and you will see the new <strong>ASH</strong> Public Service Announcement<br />

shown 18 times a day.<br />

158


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

A & D Medical<br />

Contact: Amit Ghia<br />

1756 Automation Parkway<br />

San Jose, CA 95131<br />

Phone: 408-263-5333<br />

Fax: 408-263-0119<br />

E-mail: aghia@andmedical.com<br />

Website: www.andmedical.com<br />

Booth Number: 1010<br />

A&D Medical / LifeSource manufacturers blood pressure<br />

monitors and other home health care products for home<br />

and pr<strong>of</strong>essional use. Models include automatic, manual,<br />

ambulatory, kiosk style and accessories including stethoscopes.<br />

A&D Medical is a division <strong>of</strong> A&D Engineering, and is<br />

ISO 13485:2003 certified. Since 1977, A&D Medical has<br />

manufactured and distributed a full line <strong>of</strong> advanced<br />

electronic blood pressure monitoring equipment and health<br />

care products for home and pr<strong>of</strong>essional use. The company<br />

has established itself as a leader in home health monitoring<br />

technology through the development and introduction <strong>of</strong> a<br />

variety <strong>of</strong> unique products. A&D’s LifeSource® blood pressure<br />

monitor line has garnered numerous industry awards.<br />

Recent product introductions include: the LifeSource® digital<br />

thermometers, personal scales, stethoscopes, and Ambulatory<br />

Blood Pressure Monitors.<br />

Ajinomoto USA, Inc.<br />

Contact: Junichi Tashiro<br />

400 Kelby Street<br />

Fort Lee, NJ 07024<br />

Phone: 201-292-3244<br />

Fax: 201-346-5639<br />

Email: tashiroj@ajiusa.com<br />

Booth Number: 1104<br />

Since 1909, Ajinomoto Co., a leader in the development<br />

<strong>of</strong> pharmaceutical quality amino acids and distributor <strong>of</strong><br />

products that <strong>of</strong>fer a holistic, side-effect free solution to today’s<br />

top health concerns <strong>of</strong> weight management, sleep quality<br />

improvement and healthy blood pressure management. These<br />

products are Capsiate Natura®, a patented, side effect-free<br />

dietary supplement with natural capsinoids shown to boost the<br />

body’s metabolism; Glysom, a safe, effective and scientificallyproven<br />

amino acid-based solution for deeper, sounder and<br />

more satisfying sleep, and Natura Guard BP, a milk proteinderived<br />

nutraceutical to help maintain healthy blood pressure<br />

levels already within the normal range.<br />

For more information, visit www.capsiatenatura.com,<br />

www.glysom.com and www.naturaguardbp.com<br />

159


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

AtCor Medical, Inc. (USA)<br />

Contact: Beth Boyer<br />

One Pierce Place, Suite 225W<br />

Itasca, IL 60143<br />

Phone: 630-228-8871<br />

Fax: 630-228-8872<br />

Email: info@atcormedical.com<br />

Website: www.atcormedical.com<br />

Booth Number: 1106<br />

AtCor Medical developed and markets SphygmoCor® systems,<br />

the global gold standard in noninvasive assessment <strong>of</strong> central<br />

blood pressure and arterial stiffness. Featured in over 600<br />

published studies, SphygmoCor systems are used worldwide in<br />

leading medical centers, physicians’ <strong>of</strong>fices, in research and in<br />

pharmaceutical clinical trials.<br />

Daiichi Sankyo, Inc.<br />

Contact: Ann Marie Bermudez<br />

2 Hilton Court<br />

Parsippany, NJ 07054<br />

Phone: 973-944-2600<br />

Fax: 973-944-2891<br />

Email: abermudez@dsi.com<br />

Website: www.dsi.com<br />

Booth Number: 1200<br />

Daiichi Sankyo, Inc. (DSI), headquartered in Parsippany, NJ,<br />

is the U. S. subsidiary <strong>of</strong> Daiichi Sankyo Co., Ltd., a global<br />

pharmaceutical company. DSI was formed in 2006 from the<br />

integration <strong>of</strong> two leading pharmaceutical companies, Sankyo<br />

Pharma, Inc. and Daiichi Pharmaceutical Corporation.<br />

Its team <strong>of</strong> nearly 3,000 U.S. employees is dedicated to the<br />

creation and supply <strong>of</strong> innovative pharmaceutical products to<br />

address the diversified, unmet medical needs <strong>of</strong> patients. DSI<br />

concentrates in the therapy areas <strong>of</strong> hypertension, thrombosis,<br />

dyslipidemia, diabetes and acute coronary syndrome. Clinical<br />

development and regulatory activities are headquartered at<br />

Daiichi Sankyo Pharma Development in Edison, NJ. Visit<br />

www.dsi.com.<br />

160


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

David Lerner Associates<br />

Contact: James Faillace<br />

568 Yamato Road 3rd Floor<br />

Boca Raton FL 33431<br />

Phone: 561-226-4500<br />

Fax: 561-226-4598<br />

Email: jon.jarow@davidlerner.com<br />

Booth Number: 1102<br />

Financial Investments at David Lerner Associates<br />

We believe gambling and investing are not the same.<br />

We believe the stock market should make for interesting<br />

dinner conversation but should not be a matter <strong>of</strong> financial life<br />

or death.<br />

We believe we have an obligation to guide our investors<br />

in directions we feel will help them achieve their financial<br />

objectives.<br />

We believe investors should not be chasing financial rainbows.<br />

We do not run with the herd. We pursue these fundamental<br />

investment principles regardless <strong>of</strong> market conditions.<br />

While <strong>of</strong>fering a full range <strong>of</strong> investments, we feature those that<br />

we believe are based on real value and regularly pay dividends<br />

or interest.<br />

Elsevier<br />

Contact:<br />

Jeffrey Francis<br />

Elsevier, Inc.<br />

1600 JFK Blvd. Suite 1800<br />

Philadelphia, PA 19103<br />

Phone: 215-239-3491<br />

Fax: 215-239-3494<br />

Email: j.francis@elsevier.com<br />

Website: www.elsevierhealth.com<br />

Booth Number: 1204<br />

ELSEVIER, a premier worldwide health science publishing<br />

company, is proud to publish Journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong><br />

<strong>of</strong> <strong>Hypertension</strong>, the <strong>of</strong>ficial journal <strong>of</strong> the <strong>American</strong> <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong>. Please stop by our booth to view the latest issue<br />

<strong>of</strong> the journal.<br />

161


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

Forest Pharmaceuticals, Inc.<br />

Contact: info@forestpharm.com<br />

13600 Shoreline Drive<br />

St. Louis, MO 63045<br />

Phone: 800-678-1605<br />

Fax: 314-493-7450<br />

Email: info@forestpharm.com<br />

Website: www.forestpharm.com<br />

Booth Number: 1006<br />

Forest Pharmaceuticals, Inc welcomes you to New York! We<br />

invite you to visit our exhibit. Please visit our website at<br />

www.forestpharm.com<br />

Community Partner <strong>of</strong> the <strong>ASH</strong> <strong>Hypertension</strong> Community<br />

Outreach <strong>Program</strong><br />

HoMedics<br />

Contact:<br />

Anthony Vigliotti<br />

3000 Pontiac Trail<br />

Commerce Township, MI 48390<br />

Phone: 248-863-3000<br />

Fax: 248-863-3103<br />

Email: anthony.vigliotti@homedics.com<br />

Website: www.HoMedics.com<br />

Booth Number: 1107<br />

Since HoMedics was founded in 1987, they have become the #1<br />

name in health and wellness with an extensive line <strong>of</strong> products<br />

that allow you to take a proactive role in managing your health.<br />

HoMedics blood pressure monitors are clinically proven<br />

accurate and <strong>of</strong>fer a wide range <strong>of</strong> innovative features and<br />

technologies that make monitoring your blood pressure at<br />

home easier than ever.<br />

Select arm and wrist models <strong>of</strong>fer Voice Assist® Talking<br />

Function, Supersize Digits®, Risk Category Index, Easy One<br />

Button Operation, Dual User Memory and 2 cuffs to fit most<br />

arm sizes.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong> <strong>Hypertension</strong> Community<br />

Outreach <strong>Program</strong><br />

162


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

International <strong>Society</strong> on <strong>Hypertension</strong> in Blacks, Inc. (ISHIB)<br />

Contact: Terry E. Jackson<br />

2111 Wilson Boulevard, Suite 700<br />

Arlington, VA. 22201<br />

Phone: 703-351-5023<br />

Fax: 703-351-9292<br />

Email: terry-jackson@ishib.org<br />

Website: www.ishib.org<br />

Booth Number: 1103<br />

Founded in 1986, ISHIB is a non-pr<strong>of</strong>it organization <strong>of</strong><br />

healthcare pr<strong>of</strong>essions and leaders in cardiovascular disease<br />

and related disorders. Our mission is to improve the health<br />

and life expectancy <strong>of</strong> ethnic minorities and eliminate racial<br />

and ethnic health disparities in cardiovascular disease through<br />

pr<strong>of</strong>essional and public education, targeted clinical research,<br />

and facilitation <strong>of</strong> the delivery <strong>of</strong> higher quality cardiovascular<br />

health care. We host an annual conference, membership and<br />

other programs.<br />

Lippincott, Williams & Wilkins, a Wolters Kluwer Health<br />

Company<br />

Contact: Jeff Thompson (PSG)<br />

16522 Hunters Green Parkway<br />

Hagerstown, MD 21740 U.S.A.<br />

Phone: 1-800-638-3030 (North America)<br />

+44 (0) 20 7981 0525 (Europe)<br />

1-301-223-2300 (Rest <strong>of</strong> World)<br />

Fax: 1-301-223-2400 (North America)<br />

+44 (0) 20 7981 0535 (Europe)<br />

1-301-223-2400 (Rest <strong>of</strong> World)<br />

Email: Jeff.Thompson@wolterskluwer.com or<br />

customerservice@lww.com<br />

Website: www.lww.com<br />

Booth Number: 1008<br />

Lippincott Williams & Wilkins, Wolters Kluwer Health<br />

Company, is the proud publisher <strong>of</strong> <strong>Hypertension</strong>, Journal<br />

<strong>of</strong> the <strong>American</strong> Heart Association, and the Journal <strong>of</strong><br />

<strong>Hypertension</strong>, Official Journal <strong>of</strong> the International <strong>Society</strong> <strong>of</strong><br />

<strong>Hypertension</strong> and the European <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>. We<br />

<strong>of</strong>fer a full range <strong>of</strong> specialized books, journals, and electronic<br />

media. Visit us today!<br />

163


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

Mortara Instrument<br />

Contact: Cynthia Muise<br />

7865 N. 86th Street<br />

Milwaukee, WI 53224<br />

Phone: 414-354-1600 x7738<br />

Fax: 414-354-4760<br />

Email: Cynthia.muise@mortara.com<br />

Booth Number: 1105<br />

Mortara Instrument is proud to <strong>of</strong>fer its Ambulo 2400<br />

ambulatory blood pressure (ABPM) technology at the<br />

<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Hypertension</strong>’s <strong>2011</strong> Annual Scientific<br />

Meeting and Exposition. Designed and made in the USA, the<br />

Ambulo 2400 system allows clinicians, researchers and other<br />

health pr<strong>of</strong>essionals to better assess a patient’s blood pressure<br />

fluctuations throughout the 24-hour circadian rhythm.<br />

For over 25 years, Mortara Instrument has distinguished itself<br />

in the field <strong>of</strong> non-invasive cardiology by providing ECG,<br />

Holter and stress systems to customers worldwide. We are<br />

excited to be adding thorough blood pressure assessment tools<br />

to our portfolio <strong>of</strong> products.<br />

National Kidney Foundation<br />

Contact: David Rexroad<br />

30 East 33rd Street<br />

New York, NY 10016<br />

Phone: 212-889-2210<br />

Fax: 212-889-2310<br />

Email: davidr@kidney.org<br />

Website: www.kidney.org<br />

Booth Number: 1206<br />

NKF <strong>of</strong>fers the nephrology community the latest science<br />

through clinical practice guidelines, free kidney screening<br />

programs held around the world, and educational materials for<br />

patients and pr<strong>of</strong>essionals. Learn more about the soon-to-be<br />

published guidelines, including: KDIGO’s Acute Kidney Injury<br />

and the Update on CKD and Diabetes by KDOQI. Please<br />

visit the booth to sign-up to review KDIGO’s Clinical Practice<br />

Guideline on Blood Pressure in CKD.<br />

164


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

Novartis Pharmaceuticals Corporation<br />

Contact: Becca Baileys<br />

One Health Plaza<br />

East Hanover, NJ 07936<br />

Phone: 862-778-8300<br />

Email: rebecca.baileys@novartis.com<br />

Website: www.novartis.com<br />

Booth Number: 1100, 1004<br />

Novartis Pharmaceuticals is dedicated to discovering,<br />

developing, manufacturing and marketing prescription drugs<br />

that help meet our customers’ medical needs and improve their<br />

quality <strong>of</strong> life. Please visit the Novartis exhibit where our sales<br />

representatives will be available to discuss our products.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong> <strong>Hypertension</strong> Community<br />

Outreach <strong>Program</strong><br />

Omron Healthcare<br />

Contact: Dan Aske<br />

1200 Lakeside Drive<br />

Bannockburn, IL 60015<br />

Phone: 847-680-6200<br />

Fax: 847-680-6269<br />

Email: info@omron.com<br />

Booth Number: 1000<br />

Omron Healthcare, Inc., is the leading manufacturer and<br />

distributor <strong>of</strong> blood pressure monitors for home use. Omron<br />

Healthcare markets clinically proven products that provide<br />

accurate health information to consumers and physicians and<br />

support position lifestyle changes and health improvement.<br />

Community Partner <strong>of</strong> the <strong>ASH</strong> <strong>Hypertension</strong> Community<br />

Outreach <strong>Program</strong><br />

165


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

SunTech Medical, Inc.<br />

Contact: Rod Thomson<br />

507 Airport Blvd.., Suite 117<br />

Morrisville, NC 27560<br />

Phone: +1 919 654 2300 x 355<br />

Fax: +1 919 654 2301<br />

Email: sales @suntechmed.com<br />

Website: www.SunTechMed.com<br />

Booth Number: 1014<br />

For over twenty years, SunTech Medical has been the<br />

preeminent supplier <strong>of</strong> clinical grade blood pressure<br />

monitoring products and technologies. SunTech is the<br />

world’s foremost manufacturer <strong>of</strong> ambulatory blood pressure<br />

monitors, including the Oscar 2 ABPM system, now available<br />

with Pediatric ABPM Interpretation function, which<br />

automatically generates guidelines specific to analyzing the<br />

24-hour blood pressure data <strong>of</strong> pediatric patients. Additionally,<br />

SunTech <strong>of</strong>fers solutions for in-<strong>of</strong>fice BP measurement with the<br />

SunTech 247, the first clinical grade automated blood pressure<br />

device to <strong>of</strong>fer a manual back-up mode, as well as a complete<br />

line <strong>of</strong> blood pressure cuffs. Please visit our booth for more<br />

information.<br />

Takeda Pharmaceuticals North America, Inc.<br />

Contact: One Takeda Parkway<br />

Deerfield, Il 60015<br />

Phone: 224-554-6500<br />

Website: www.tpna.com<br />

Booth Number: 1400<br />

Based in Deerfield, IL. Takeda Pharmaceuticals North<br />

America, Inc. and Takeda Global Research & Development<br />

Center, Inc. market oral diabetes, insomnia, rheumatology<br />

and gastroenterology treatments and seek to bring innovative<br />

products to patients through a pipeline that includes<br />

compounds in development for diabetes, cardiovascular<br />

disease, gastroenterology and neurology. www.tpna.com.<br />

166


<strong>2011</strong> <strong>ASH</strong> Exhibitors continued<br />

Wiley-Blackwell<br />

Contact: 350 Main Street<br />

Malden, MA 02148<br />

Phone: 781-388-8250<br />

Fax: 781-338-8250<br />

Website: www.wiley.com<br />

Booth Number: 1202<br />

Wiley-Blackwell is the international scientific, technical,<br />

medical and scholarly publishing business <strong>of</strong> John Wiley &<br />

Sons, with strengths in every major academic and pr<strong>of</strong>essional<br />

field and partnerships with many <strong>of</strong> the world’s leading<br />

societies. Wiley-Blackwell publishes over 1,400 peer-reviewed<br />

journals as well as 1,500+ new books annually in print and<br />

online, as well as databases, major reference works and<br />

laboratory protocols. For more information, please visit<br />

www.wileyblackwell.com or http://onlinelibrary.wiley.com/<br />

WomenHeart<br />

Contact: Mary McGowan, COO<br />

818 18th Street NW<br />

Washington DC 20006<br />

Phone: 202-464-8735<br />

Email: mmcgowan@womenheart.org<br />

Website: www.womenheart.org<br />

Booth Number: 1110<br />

WomenHeart was founded by three women who had heart<br />

attacks while in their 40s. In addition to being faced with many<br />

obstacles, including misdiagnosis and social isolation, they<br />

were each amazed how little information about or services for<br />

women with heart disease were available and how the issue<br />

seemed invisible within the women’s health community. But in<br />

March 1999 everything changed.<br />

167


Author Index<br />

A<br />

Abad, María, 133<br />

Abaunza, Ricardo, 102<br />

Abbey, Susan, 136<br />

Abdallah, Rany T., 101<br />

Abdellatifi, Ibrahim L., 142<br />

Abecasis, Goncalo R., 79<br />

Abraham, Nader G., 66, 122<br />

Abramson, Beth, 136<br />

Acelajado, Maria Czarina, 88, 108,<br />

138<br />

Acelajado, Maria Czarina M., 120<br />

Acelajado‐Valdenor, Ma Czarlota<br />

M., 120<br />

Achouba, Assya, 92, 127<br />

Adamczyk, Maciej, 142<br />

Adams, Kenneth F., 106<br />

Adams, Robert J., 100, 102, 134<br />

Adler, G., 97<br />

Agarwal, Rajiv, 60, 145<br />

Agarwal, Vikram, 66, 93, 117<br />

Agarwal, Vikram V., 87, 117<br />

Aggelis, A., 66, 91, 124<br />

Agnoletti, Davide, 112, 126, 128<br />

Aguilar, Francisco, 101<br />

Ajzen, Sérgio Aron, 102<br />

Albarran, Olga Gonzalez, 99<br />

Alcon, Jose, 101<br />

Alebiosu, Olutayo Christopher, 97<br />

Alessi, Sheila M., 136<br />

Almenar, Luis, 116<br />

Almiroudi, M., 92, 96, 102, 122,<br />

124, 126<br />

Alonso, Ana, 91, 98<br />

Alonso, Ignacio, 114, 129<br />

Altun, Bulent, 97, 121<br />

Alvarez, Carlos, 98<br />

Alvarez, Carmen, 139<br />

Alvarez, Julio, 101<br />

Ambalavanan, Namasivayam, 118,<br />

144<br />

Ambrosio, Giuseppe, 91<br />

Amdur, Richard, 96, 105<br />

Amin, M. Yousri K., 142<br />

Ammary, Ibtissam, 141<br />

Anastasopoulos, I., 128<br />

Andrews, L. M., 133, 140<br />

Andrikou, E., 122, 126<br />

Andrikou, I., 92, 102, 122<br />

Angelini, Luca, 120<br />

Antonino, Cassi, 137<br />

Anunciato, Iara F., 143<br />

Anunciato, Iara Felício, 132<br />

Aonuma, Takanori, 117<br />

Appel, Lawrence J., 82, 145<br />

Aragiannis, D., 102<br />

Aranda, Pedro, 101, 102<br />

Arbique, Debbie, 59<br />

Arici, Mustafa, 97<br />

Arinsoy, Turgay, 121<br />

Armando, Ines, 47, 97, 123<br />

Arnett, Donna K., 145<br />

Aronne, Luigi, 123<br />

Artinian, Nancy, 45, 145<br />

Asche, Stephen E., 89<br />

Ascione, Frank, 87<br />

Asico, Laureano, 97<br />

Asico, Laureano D., 47<br />

Aslam, S., 91<br />

Asmar, Ali, 78<br />

Assia, Ehud, 103<br />

Ates, Kenan, 121<br />

Atkinson, Hal, 61<br />

Atluri, Tej K., 117<br />

Aucott, Lorna, 137<br />

August, Phyllis, 43, 145<br />

Aviv, Abraham, 76, 145<br />

Axon, R. Neal, 105, 130<br />

Ayala, Carma, 129<br />

Ayala, Diana E., 60, 97, 98, 99, 108,<br />

110, 111, 114, 121, 129, 131<br />

Azar, Silvia H., 123<br />

B<br />

Baba, Yoshichika, 121<br />

Babazadeh, Simon, 98<br />

Baber, Nigel, 95<br />

Bachman, David L., 134<br />

Bae, Jong‐Hoa, 116<br />

Baek, InYoung, 130<br />

Bagrov, Alexei Y., 142, 143<br />

Bailey, M., 97<br />

Bajaj, Jennifer, 90<br />

Baker, Brian, 136<br />

Baker, William L., 109<br />

Bakhtar, Omid, 93<br />

Bakris, George, 67, 78, 99<br />

Bakris, George L., 44, 50, 58, 68, 75,<br />

76, 78, 112, 140, 145<br />

Bakris, G. L., 115<br />

Balbarini, Alberto, 116, 126<br />

Baldo, Manuela S., 87<br />

Baldwin, William, 100<br />

Balish, Marshal, 136<br />

Ballesteros, Maria Jose, 95<br />

Baltatzi, Maria, 111<br />

Bancr<strong>of</strong>t, T. J., 140<br />

Bandyopadhyay, Dipankar, 110<br />

Banegas, Jose R., 93, 123, 134<br />

Baraniuk, Sarah, 60<br />

Baranova, Elena I., 87<br />

Barbatelli, Paolo, 133<br />

Barbetseas, I., 61<br />

Barbosa, Loide, 96<br />

Bard, Robert L., 65, 129<br />

Barros, Jesús, 129<br />

Baschiera, Fabio, 130<br />

Basile, Jan, 98, 130<br />

Basile, Jan N., 49, 50, 64, 145<br />

Bastien, Carl, 127<br />

Bastos, Jose Mesquita, 129, 134<br />

Basu, Sanjib, 47, 113<br />

Batisky, Donald L., 40, 51, 145<br />

Batson, Bryan, 139<br />

Baur, Dorothee M., 95<br />

Bavisotto, Susan Harris, 140<br />

Baylis, Chris, 100<br />

Bayorh, Mohamed A., 107<br />

Bellavia, Diego, 116<br />

Bellner, Lars, 122<br />

Belyaeva, Olga D., 87<br />

Ben‐Dov, Iddo Z., 93<br />

Benedict, Patrick E., 141<br />

Benetos, Georgios N., 119<br />

Berenson, Abbey B., 95, 102<br />

Berenson, Gerald S., 93, 94, 127<br />

168


Author Index<br />

Berezina, Aelita V., 87<br />

Berkovich, Olga O., 87<br />

Berktas, Mehmet, 108<br />

Bernard, Gutin, 47<br />

Bernheim, Jacques, 131<br />

Bernstein, Ira, 142<br />

Berrios, Ronaldo Sevilla, 110<br />

Bertoquini, Susana, 129<br />

Bertoquini, Susana P., 137<br />

Bhabhe, Aditya S., 123, 132<br />

Bhaheetharan, Sujan, 110<br />

Bhandari, Simran, 67<br />

Bhandari, Simran K., 108<br />

Bianchini, Elisabetta, 91, 127<br />

Biggi, Almerina, 91<br />

Bisognano, John, 67<br />

Bisognano, John D., 40, 49, 67, 126,<br />

145<br />

Blacher, Jacques, 99, 112, 126, 128<br />

Black, Henry R., 40, 81, 145<br />

Bloch, Michael J., 50, 145<br />

Blom, Kimberly C., 136<br />

Blue, Amanda E., 101<br />

Blumenthal, James A., 131<br />

Boan, Andrea D., 102, 134<br />

Boateng, Frank K., 139<br />

Bobrie, Guillaume, 108<br />

Bochud, Murielle, 79<br />

Boden, William E., 44<br />

Boerrigter, Guido, 91<br />

Bolin, Paul, 124<br />

Bolondi, Luigi, 95<br />

Bolshakova, Olga O., 87<br />

Bolton, Charlotte, 128<br />

Bonartseva, Garina A., 108<br />

Bonartsev, Anton P., 108<br />

Borghi, Claudio, 93<br />

Bosi, Matteo, 130, 137<br />

Bougatsa, Vaia, 111<br />

Bowden, Charles, 78<br />

Boyaci, Bulent, 108<br />

Bracho, Mayela J., 87<br />

Brady, Tammy M., 101<br />

Brands, Michael W., 40, 72, 145<br />

Brashear, R. Jeffrey, 142<br />

Braucht, Drew, 101<br />

Braun‐Dullaeus, Rudiger C., 139<br />

Braun, Lynne T., 45, 145<br />

Bravo, Emmanuel, 50, 145<br />

Briasoulis, Alex, 93, 117<br />

Briasoulis, Alexandros, 87, 117<br />

Bridges, William, 102<br />

Brinson, Stephanie, 140<br />

Brook, Robert D., 65, 129<br />

Brosolo, Gabriele, 136<br />

Brough, Elizabeth, 90, 115<br />

Brown, Angela L., 49, 50, 146<br />

Brown, Michael D., 136, 138, 144<br />

Brown, Morris, 112<br />

Brown, Nancy J., 40, 146<br />

Brunel, Patrick, 130<br />

Bruno, Rosa Maria, 127<br />

Brzezinski, W. Adam, 130<br />

Bueno, Isabel, 129<br />

Buglioni, Alessia, 107<br />

Buren, Peter Van, 60<br />

Burnett, John C., 91, 116<br />

Burnett, Jr., John C., 47<br />

Burnett, Richard T., 129<br />

Burney, Basil, 99<br />

Burri, Philippe, 143<br />

Bursztyn, Michael, 93<br />

Bushinksy, David A., 146<br />

Bushinsky, David, 107<br />

Bushinsky, David A., 70<br />

Bustamante, Eduardo E., 138<br />

Buysman, E. K., 140<br />

Byun, Young‐Sup, 118, 119, 120<br />

C<br />

Cafazzo, Joseph, 132<br />

Caglar, Sali, 97<br />

Cai, Jingjing, 112<br />

Cain, Van, 118<br />

Calabrò, Raffaele, 123<br />

Calara, Federico, 67<br />

Calara, Federico B., 108<br />

Calderon, Berniza, 91<br />

Calderón, Berniza, 99<br />

Calhoun, David A., 88, 108, 138<br />

Callejas, Pedro A., 97, 131<br />

Calmon, Gustavo E., 87<br />

Calvo, Sara, 91<br />

Campbell, Norman R.C., 54, 146<br />

Campbell, Patrick T., 109, 136<br />

Campese, Vito M., 88<br />

Campoy, Jose, 98<br />

Camsari, Taner, 121<br />

Cañas, Juan, 129<br />

Cannone, Valentina, 47, 91<br />

Cano, Marta, 91, 99<br />

Cao, C., 115<br />

Cao, Charlie, 112<br />

Capobianco, Frine, 88<br />

Carlberg, Bo, 93<br />

Carnevale, Daniela, 134, 135<br />

Carrasco, Marta, 91, 99<br />

Carreño, Agustin, 95<br />

Carretero, Oscar A., 20, 76, 146<br />

Carter, Barry L., 45, 49, 146<br />

Carugo, S., 130<br />

Cassi, Antonino, 130<br />

Castillo, Zenaida, 127<br />

Castiñeira, Maria C., 99, 121<br />

Castresana, Elena, 91<br />

Cataliotti, Alessandro, 22, 47, 76, 91,<br />

116, 146<br />

Catena, Cristiana, 59, 88, 136<br />

Caulfield, Mark, 78<br />

Caulfield, Mark J., 79<br />

Celis, Susana I., 127<br />

Cerezo, Cesar, 67, 93, 96<br />

Chacko, Billy G., 117<br />

Chakravarti, Aravinda, 78, 79<br />

Chamarthi, B., 97<br />

Charney, Alan, 130<br />

Chasman, Daniel I., 79<br />

Chavanu, Kathleen J., 114, 115<br />

Chayan, Luisa, 60, 114, 129<br />

Chazova, I. E., 143<br />

Chazova, Irina E., 112<br />

Cheh, Christopher Newton, 79<br />

Cheng, Dunlei, 94<br />

Chen, W., 113<br />

Chen, Wei, 93, 94, 122<br />

169


Author Index<br />

Chen, Yiu‐Fai, 103, 118, 126, 144<br />

Cheruvu, Bharadwaj, 122<br />

Cheung, D. G., 113<br />

Childers, W. Kurtis, 47<br />

Chlapoutakis, G., 126<br />

Cho, Eun‐Joo, 88<br />

Choi, Kyu‐Young, 88<br />

Cho, Jin‐Man, 111, 116<br />

Chow, Josephine X., 87<br />

Christensen, Niels Juel, 78<br />

Christiano, Cindy, 124<br />

Chrysant, Steven G., 109, 111<br />

Chung, Wook‐Jin, 118, 119, 120<br />

Chung, Yeonseung, 132<br />

Cicero, Arrigo, 93<br />

Cifelli, Giuseppe, 134, 135<br />

Cinteza, Mircea, 143<br />

Cirillo, Chiara, 123<br />

Civitarese, Louis, 141<br />

Clark, Rebecca I., 127<br />

Clark, Sarah, 87<br />

Clar, Xavier, 105<br />

Clyburn, Benjamin, 130<br />

Cockcr<strong>of</strong>t, John R., 46, 95, 128, 138,<br />

146<br />

Coelho, Eduardo B., 143<br />

Cohen, Debbie L., 127<br />

Cohn, Jay N., 51, 116, 144, 146<br />

Cohn, Lisa, 87<br />

Colaco, Clinton, 107<br />

Colby, Chris, 89<br />

Coloma, Ramon, 129<br />

Colussi, Gian Luca, 59<br />

Colussi, GianLuca, 59, 88, 136<br />

Comisky, Lauren, 123<br />

Concilio, Claudia, 123<br />

Connell, Barry, 92<br />

Corlan, Alexandru, 143<br />

Cornelissen‐Guillaume, Germaine<br />

G., 137<br />

Cosentino, Eugenio Roberto, 93<br />

Cosentino, Francesco, 91<br />

Couch, Sarah C., 106<br />

Coulson, James M., 138<br />

Craft, Chanda, 102<br />

Credendino, Maria, 123<br />

Crespo, Juan J., 97, 98, 121, 131<br />

Crippa, Giuseppe, 130, 137<br />

Croghan, Carry, 129<br />

Crowley, Steven D., 40, 146<br />

Cuevas, Santiago, 97<br />

Cui, Rong, 112<br />

Cushman, W. C., 115<br />

Cushman, William C., 54, 62, 78,<br />

112, 146<br />

D<br />

d’Addato, Sergio, 93<br />

D’Agostino, Ralph B., 96<br />

Dahlström, John K. F., 93<br />

Daley, Matt F., 106<br />

Damasceno, Albertino, 96<br />

Daniels, Stephen R., 47, 106, 146<br />

Daoud, Yahya, 94<br />

Darabont, Roxana O., 143<br />

Dart, Richard A., 135<br />

DasMahapatra, Pronabesh, 93, 94<br />

Dastani, H. B., 140<br />

Davidson, Michael H., 44, 146<br />

Davis, Barry R., 60<br />

Day, Wesley, 78<br />

De Angulo, Guillermo A., 100<br />

Dean, Lacy, 124<br />

Debenham, Ellen, 100<br />

Deedwania, P., 113<br />

Deghedi, Akram A., 142<br />

de la Cruz, Jose Juan, 101, 102<br />

de la Cruz, Juan J., 93, 123, 133, 134<br />

de la Sierra, Alejandro, 102, 105,<br />

123, 133, 134<br />

de la Sierra, Alex, 101<br />

De la Torre, Nuria, 47, 91, 92, 98<br />

Delgado‐Leon, Antonio J., 127<br />

de Lis, Jesus Perez, 99<br />

Del Tío, Rocío, 129<br />

Derici, Ulver, 97<br />

De Rosa, Maria Leonarda, 113<br />

Desai, Tejas, 122, 124<br />

DeSouza, Christopher A., 92<br />

Dessì-Fulgheri, Paolo, 120<br />

Dessì‐Fulgheri, Paolo, 107, 133<br />

Destounis, Antonios, 134<br />

Destounis, Antonis, 105<br />

DeVries, Andrea, 122<br />

Dhaun, N., 97, 121<br />

Diaz, Edgar A., 132<br />

Diaz, Keith M., 136, 144<br />

Díaz, María T., 129<br />

Di Bello, Vitantonio, 116, 126<br />

Dimitriadis, K., 66, 91, 92, 124, 126,<br />

128<br />

Diogo, Domingos, 96<br />

Dionne, Janis M., 87<br />

Dixon, John, 139<br />

Djordjevic, Dragan, 120<br />

Dobrokhod, Anna S., 133<br />

Dochee, Jennifer D., 107<br />

Does, Alec V., 90<br />

Dolan, Lawrence M., 106<br />

Dolz, Luis Martínez, 116<br />

Dominguez, Maria J., 114, 129<br />

Dominguez‐Sardiña, Manuel, 98,<br />

111, 121, 131<br />

Dongre, Neelesh, 94, 112<br />

Dong, Yanbin, 47<br />

Dormi, Ada, 93<br />

Doumas, Michael, 94, 96, 136<br />

Dourliou, Vasiliki, 111<br />

Drawz, Paul E., 60<br />

Dresser, George K., 141<br />

Dresser, G. K., 89<br />

Dubiel, Robert, 114, 115<br />

Dudenbostel, Tanja, 88, 108, 138<br />

Duh, Mei Sheng, 110, 131, 133<br />

Duprez, Daniel, 73, 109, 116, 130,<br />

146<br />

Duprez, Daniel A., 144<br />

Dvonch, J. Timothy, 65<br />

Dworkin, Lance D., 56, 146<br />

E<br />

Eatman, Danita, 107<br />

Ecder, Tevfik, 121<br />

Eckeli, Alan L., 143<br />

Egan, Brent, 105, 110, 130, 134<br />

Egan, Brent M., 40, 49, 134, 140, 147<br />

170


Author Index<br />

Eguchi, Kazuo, 110, 132<br />

Ehret, Georg, 78<br />

Ehret, Georg B., 79<br />

Einhorn, Paula T., 49, 147<br />

Eiroa, Peregrina, 97, 131<br />

Eisenberg, Debra F., 122<br />

Eleftheriadou, I., 122<br />

Eliseyeva, Marietta, 117<br />

Elliott, Paul, 79<br />

Elliott, William J., 47, 50, 61, 73, 113,<br />

140, 147<br />

Ennis, Riley C., 122<br />

Entcheva, Miglena, 93, 94<br />

Epstein, Benjamin J., 115<br />

Epstein, Michael J., 133<br />

Epstein, Murray, 24, 70, 76, 77, 147<br />

Erbay, Bulent, 97<br />

Erdem, Yunus, 97<br />

Escano, Crisanto, 97<br />

Esis, Carlos E., 87<br />

Esler, Murray D., 77, 138, 147<br />

Espinosa, Emma, 133<br />

Esposito, A., 130<br />

Eto, Masahiko, 117<br />

Eto, Tanenao, 114<br />

Eunsil, Yim, 100<br />

Evans, Gregory, 61<br />

Evora, Paulo R. B., 143<br />

Exuzides, Alex, 89<br />

F<br />

Fabregate, Martin, 47, 91, 92, 98, 110<br />

Fabregate, Rosa, 47, 91, 92, 98, 110<br />

Faillace, Robert T., 140<br />

Faita, Francesco, 91, 127<br />

Falck, John R., 66<br />

Falkner, Bonita, 40, 147<br />

Falvey, Heather, 110, 131<br />

Familoni, Oluranti, 97<br />

Fang, Christy, 122<br />

Fang, Jing, 136<br />

Fares, Maria Luisa, 130<br />

Farooqi, Sadaf, 58, 147<br />

Faselis, Charles, 94, 96, 105, 136<br />

Fawzy, Abdelmoneim A., 142<br />

Feagan, B. G., 89<br />

Feagan, Brian G., 141<br />

Feairheller, Deboarh L., 144<br />

Feairheller, Deborah L., 136, 138<br />

Fedecostante, Massimiliano, 133<br />

Fedorova, Olga V., 142, 143<br />

Fedorov, Sergiy V., 92<br />

Fedrizzi, Stefania, 88<br />

Feibel, Hedy, 123<br />

Feig, Daniel I., 66, 106, 147<br />

Feig, Denice, 132<br />

Feldman, R. D., 89<br />

Feldman, Ross, 54, 147<br />

Feldman, Ross D., 141<br />

Ferdinand, Keith, 105, 109, 130<br />

Ferdinand, Keith C., 44, 62, 110, 113,<br />

114, 147<br />

Ference, Brain, 107<br />

Ference, Brian A., 93<br />

Fernandes, Regina M. R., 143<br />

Fernandez, Angelica, 47, 91, 98, 110<br />

Fernandez, Camilo, 93, 94, 127<br />

Fernandez, Jose Carlos, 101, 102<br />

Fernandez, Jose R., 60, 97, 99, 108,<br />

110, 111, 114, 121, 129, 131<br />

Fernandez, Olga, 98<br />

Fernandez, Rafael, 109<br />

Fernandez, Victor, 109, 111<br />

Ferrario, Carlos M., 89<br />

Ferreras, Amelia, 121<br />

Ferrero, David, 133<br />

Ferrero‐Martinez, Ana Isabel, 120<br />

Ferriolli, Eduardo, 132, 143<br />

Ferris, Maria, 122<br />

Figueiredo, José Nuno, 134<br />

Filatova, Elena A., 108<br />

Filho, Sebastião R., 123<br />

Fiorentini, Lucia, 137<br />

Fiquet, Béatrice, 140<br />

Fivush, Barbara A., 101<br />

Flack, John, 107, 141<br />

Flack, John M., 62, 93, 114, 147<br />

Fleg, Jerome L., 90<br />

Flessas, D., 66, 126<br />

Fletcher, Ross, 94, 136<br />

Fletcher, Ross D., 96, 105<br />

Florea, Natalia, 116<br />

Flori, Serena, 95<br />

Flynn, Joseph, 101<br />

Flynn, Joseph T., 40, 58, 101, 106,<br />

147<br />

Fogari, Roberto, 87, 88<br />

Fogg, Louis, 138<br />

Foiato, Tariane F., 87<br />

Fontao, Maria J., 60, 99, 110, 111,<br />

114, 121, 129, 131<br />

Forker, Alan, 139<br />

Forrest, Brian, 89, 140<br />

Fortunati, Marco, 120<br />

Fox, Caroline S., 117<br />

Fragasso, Gabriele, 116<br />

Franchi, Eliana, 107<br />

Francillon, Alain, 140<br />

Franklin, Stanley S., 46, 147<br />

Fraser, William D., 137<br />

Frassetto, Lynda A., 98<br />

Frazer, Lauren C., 123<br />

Frech‐Tamas, Feride, 133<br />

Freed, Gary, 87<br />

Freitas, Joao, 135, 138<br />

Frishman, William H., 64, 147<br />

Froehlich, James B., 49, 147<br />

Fromer, Leonard M., 50, 147<br />

Frome, Wayne L., 135<br />

Fujii, Kenji, 130<br />

Fujimoto, Tetsuya, 99<br />

Fu, Qi, 142<br />

G<br />

Gaciong, Zbigniew, 138<br />

Gaida, Susan, 93, 94<br />

Galbreath, M. Melyn, 142<br />

Galgo, Alberto, 98<br />

Gaman, Iryna O., 119<br />

Ganotakis, Emmanuel S., 100<br />

Garcia‐Donaire, Jose A., 67, 96<br />

García‐Ortiz, Luis, 133<br />

Garg, Suchita, 133<br />

Garoufalis, Stefanos H., 119<br />

Garrett, Andrew T., 95<br />

Garvin, Jeffrey L., 80, 147<br />

171


Author Index<br />

Gassman, Jennifer, 115<br />

Gavish, Dov, 124<br />

Gavras, Haralambos, 52, 148<br />

Gavrilov, I. Y., 143<br />

Gemignani, Vincenzo, 91, 127<br />

Georgiadis, Ioannis V., 119<br />

Georgiopoulos, Georgios E., 119<br />

Germino, F. W., 131<br />

Germino, F. Wilford, 49, 148<br />

Germino, Megan M., 131<br />

Ghannad, Emmanuel, 92, 127<br />

Ghiadoni, Lorenzo, 91, 127<br />

Giakoumis, M., 122, 126<br />

Gialernios, T., 94<br />

Giannini, Elena, 133<br />

Gibstein, Raz, 103<br />

Gijon, Teresa, 105<br />

Giles, Thomas D., 47, 127, 140, 148<br />

Giovas, Periklis, 106<br />

Giralt, Patricio, 95<br />

Girerd, Xavier, 140<br />

Glasser, Stephen P., 108<br />

Go, Alan S., 81<br />

Goddard, J., 121<br />

Godleski, John J., 132<br />

Golan, Eliezer, 131<br />

Goldberg, Ruthie, 131<br />

Gomara, Sonia M., 98, 99<br />

Gómez, Manuel, 133<br />

Gong, Kaizheng, 118, 126, 144<br />

Gongora, Maria C., 122<br />

Gonzalez‐Albarran, Olga, 91<br />

Gonzalez, Alicex C., 87<br />

Gonzalez, Olga, 98<br />

Gonzalez, Santiago Cuevas, 47<br />

Gonzalez, Waddy, 110<br />

Gopalakrishnan, Kathirvel, 137<br />

Gorostidi, Manuel, 101, 102, 105,<br />

123, 134<br />

Gradman, Alan H., 54, 110, 131, 148<br />

Graeme, Katelyn, 101<br />

Graff, Alan, 114, 115<br />

Granato, Chiara, 123<br />

Grandits, Gregory A., 144<br />

Granger, Joey P., 43, 77, 148<br />

Grant, Joshua, 93, 94<br />

Greco, Barbara A., 139<br />

Green, Kelley R., 140<br />

Greenway, Frank L., 137<br />

Greiner, Jared J., 92<br />

Grennberg, George, 103<br />

Grima, Esther Zorio, 116<br />

Grim, Clarence E., 107, 142<br />

Grimm, Jr., Richard H., 57<br />

Grimm, Richard H., 148<br />

Grosman, Ehud, 124<br />

Grossman, Ehud, 103<br />

Guedj, Dominique, 92, 127<br />

Guenoun, Maxime, 92, 127<br />

Guerra, Federico, 107, 120, 133<br />

Guerri, Asuncion, 47, 98, 110<br />

Gunawardhana, Lhanoo, 100<br />

Guo, Yuan, 53, 148<br />

Gupta, Alok K., 137<br />

Gutierrez, G., 95<br />

H<br />

Hadker, Nandini, 133<br />

Hage, Fadi, 118, 126<br />

Hage, Fadi G., 103<br />

Hailpern, Susan M., 101<br />

Halberg, Franz, 132<br />

Halfon, Sherin, 107<br />

Hall, Jennifer, 116<br />

Hall, John E., 43, 59, 148<br />

Halpern, Michael, 141<br />

Hamad, Mazen, 89<br />

Hames, Melanie, 124<br />

Hamilton, Bruce, 61<br />

Handler, Joel, 40, 90, 131, 140, 148<br />

Hansen, Kimberley J., 117<br />

Hans, Nidhi, 66, 117<br />

Haque, Tahir, 92, 110<br />

Harats, Dror, 124<br />

Harb, Mohamed A., 142<br />

Harder, David, 57, 148<br />

Harrison, David G., 57, 72, 76, 122,<br />

148<br />

Harris, Raymond C., 65, 148<br />

Hartmann, Camila, 87<br />

Hasanoglu, Enver, 97<br />

Hasegawa, Kenichi, 59<br />

Hatzitolios, Apostolos I., 111<br />

Hatzopoulos, Anastasios, 111<br />

Haun, Daniel W., 91<br />

Hayakawa, Manabu, 118<br />

Hebert, Christopher, 94<br />

Hedquist, Lowell, 93, 107<br />

Heilbraun, Jeffrey, 124<br />

Hermida, Ramon C., 60, 65, 97, 98,<br />

99, 108, 110, 111, 114, 121, 129,<br />

131<br />

Hernaiz, Susana, 99<br />

Heublein, Denise M., 91<br />

Heyrman, Reinilde, 109, 111<br />

Hill, Joseph A., 76, 148<br />

Hinderliter, Alan L., 131<br />

Hollenberg, Norman K., 76, 148<br />

Holmstedt, Christine A., 102<br />

Hongyo, Kazuhiro, 121<br />

Hopkins, P., 97<br />

Hoshide, Satoshi, 102, 110, 132<br />

Ho, Timothy, 131<br />

Houston Miller, Nancy, 40, 45, 150<br />

Howard, Barbara V., 90<br />

Hoyem, Ruby, 138<br />

Hsueh, Willa, 138<br />

Hsu, Stephen C., 142<br />

Htun, Wah Wah, 127<br />

Htyte, Nay, 110<br />

Huang, I.‐Zu, 107<br />

Huang, Zhijun, 112<br />

Hughes, Suzanne, 45, 148<br />

Hull, Pamela, 118<br />

Hunt, Barbara, 100<br />

Huntley, Brenda K., 91<br />

Husaini, Baqar, 118<br />

Hwang, Shih‐Jen, 117<br />

Hygia, Investigadores Proyecto, 97,<br />

98, 99, 111, 121, 131<br />

I<br />

Iaria, Pierre, 126<br />

Ibrahim, Mediha, 127<br />

Ichiki, Tomoko, 47<br />

IIonze, Onyedika John, 126<br />

172


Author Index<br />

Ikeda, Yasuhiro, 116<br />

Imamura, Takuro, 96<br />

Inrig, Jula K., 60, 121, 122<br />

Ioannidis, Antonios, 100, 115<br />

Irvine, Jane, 132, 136<br />

Ishikawa, Joji, 126, 132<br />

Ishikawa, Shizukiyo, 110, 126<br />

Ishizaka, Nobukazu, 59<br />

Ito, Sadayoshi, 67<br />

Iwakura, Yoshitugu, 67<br />

Izzo, Joseph, 109, 111<br />

Izzo, Joseph L., 111, 128<br />

Izzo, Jr., Joseph L., 61, 114, 148<br />

J<br />

Jackson, Sharron M., 101<br />

Jaffe, Marc G., 61<br />

Jaimes, Edgar A., 52, 113, 114, 148<br />

Jamerson, Kenneth, 90, 115<br />

Jamerson, Kenneth A., 62, 149<br />

Jang, Sung‐Won, 88<br />

Jarvis, Sara S., 142<br />

Jason, Yap, 122<br />

Jatte, Fernanda, 132<br />

Jauch, Edward C., 102<br />

Javier, Angelo Dave C., 120<br />

Jin, Eun‐Sun, 111, 116<br />

Joe, Bina, 137<br />

Johannsen, Darcy, 137<br />

Johnson, Andrew D., 79<br />

Johnson, Julie A., 42, 115, 149<br />

Johnson, Mary A., 101<br />

Johnson, Richard J., 66, 100, 149<br />

Johnson, Toby, 78, 79<br />

Johnson, William D., 137<br />

Jones, John E., 122, 123<br />

Jones, Ronald, 105<br />

Jose, Pedro A., 47, 51, 97, 122, 123,<br />

149<br />

Joshi, Nomita, 102<br />

Josse, Robert, 61<br />

Joyner, JaNae, 89, 139, 140, 141<br />

Juncos, Luis, 52<br />

Juncos, Luis I., 149<br />

Jurgens, Julie A., 122<br />

K<br />

Kaciroti, Niko, 65<br />

Kaeser, Martha A., 91<br />

Kagan, Alexander, 123<br />

Kahan, Jonathan, 107<br />

Kajii, Eiji, 117<br />

Kakinoki, Shigeo, 99<br />

Kalantar‐Zadeh, Kamyar, 108<br />

Kales, Stefanos N., 95<br />

Kallikazaros, I., 92<br />

Kalpatthi, Ram V., 101<br />

Kamal, Khalid M., 141<br />

Kambona, Joseph, 141<br />

Kamide, Kei, 95, 121<br />

Kamran, Haroon, 127, 128<br />

Kanda, Kouichi, 99<br />

Kanter, Michael, 131<br />

Kantola, Ilkka M., 114<br />

Karan, Shaila, 111, 114, 128<br />

Karatan, Oktay, 97<br />

Kario, Kazuomi, 96, 102, 110, 118,<br />

126, 132<br />

Karpanou, Eva, 61, 94, 135<br />

Karpettas, Nikolaos, 134<br />

Karpettas, Nikos, 105<br />

Karpov, Yuri A., 112<br />

Kartalis, Athanasios N., 119<br />

Kasiakogias, A., 92, 96, 124, 128<br />

Kato, Johji, 114<br />

Kavey, Rae‐Ellen W., 58, 149<br />

Kawai, Tatsuo, 121<br />

Kawakami, Tomoko, 122<br />

Kayaba, Kazunori, 126<br />

Keenan, Nora L., 129, 136<br />

Kefala, A., 124<br />

Kerby, Tessa J., 89<br />

Kereiakes, Dean J., 109, 111<br />

Kershaw, David, 87<br />

Kerwin, Todd, 116<br />

Kettner, Norman W., 91<br />

Kevorkov, Amayak, 117<br />

Khan, Bobby V., 92, 110<br />

Khan, Shahnaz, 141<br />

Kharbanda, Elyse O., 106<br />

Kheirbek, Raya, 94, 136<br />

Kheirbek, Rhea, 136<br />

Kheterpal, Sachin, 141<br />

Khosla, Shikha, 136<br />

Khoury, Philip R., 106<br />

Kimball, Thomas R., 106<br />

Kim, Catherine, 60, 121, 122<br />

Kim, Chong‐Jin, 111, 116<br />

Kim, Dong‐Bin, 88<br />

Kim, DongHyun, 66<br />

Kim, Jae‐Hyung, 88<br />

Kimura, Joe, 131<br />

Kintis, K., 92, 96, 102, 126<br />

Kirkineska, Lambrini, 111<br />

Kirpalani, Ashok L., 123, 132<br />

Kirpalani, Dilip A., 123, 132<br />

Kitamura, Kazuo, 96, 114<br />

Kita, Toshihiro, 114<br />

Kitzman, Dalane, 107<br />

Kizilirmak, Pinar, 108<br />

Kluth, D. C., 97<br />

Kobayashi, Takeshi, 99<br />

Kobayashi, Tatsuya, 130<br />

Kohan, Donald E., 80, 149<br />

Kokkinos, Peter, 94, 96, 136<br />

Kollias, Anastasios, 105, 106<br />

Kordalis, A., 96, 102, 122, 124, 128<br />

Koren‐Morag, Nira, 103<br />

Kostic, Svetlana, 116, 120<br />

Koulousios, Konstantinos, 111<br />

Kountz, David S., 82, 149<br />

Krak<strong>of</strong>f, Lawrence R., 47, 63, 149<br />

Kretzschmar, Jan, 136, 138, 144<br />

Kroner, Beverly, 90<br />

Krum, Henry, 67, 149<br />

Kudo, Masataka, 67<br />

Kudyakov, Rustam, 94<br />

Ku, Elaine, 88<br />

Kumada, Maki, 117<br />

Kumarasamy, Sivarajan, 137<br />

Kumar, Sanjay, 119<br />

Kupfer, S., 115<br />

Kupfer, Stuart, 78, 112<br />

Kuritzky, Louis, 49, 149<br />

Kuroki, Kazuo, 118<br />

Kurtz, Theodore W., 42, 149<br />

173


Author Index<br />

Kushner, Robert F., 40, 149<br />

Kuznetsov, N. S., 143<br />

Kwiatkowski, Janet L., 100<br />

Kwon, Beom‐June, 88<br />

Kyvelou, S., 66<br />

Kyvelou, Stella Maria, 61, 94, 135<br />

L<br />

Labarthe, Darwin, 137<br />

Lackland, Daniel, 89, 110, 130<br />

Lackland, Daniel T., 62, 100, 102,<br />

134, 149<br />

Lafeuille, Marie‐Hélène, 110, 131<br />

Laghi, Luca, 93<br />

Lai, Hsiao, 124<br />

Lainscak, Mitja, 107<br />

Lai, Wen‐Ter, 94<br />

Lakatta, Edward G., 46, 142, 143,<br />

149<br />

Laken, Marilyn, 130<br />

LaMarca, Babbette, 72, 149<br />

Lambert, Gavin W., 138<br />

Lamoureux, Denise P., 132<br />

Lancioni, Letizia, 133<br />

Lande, Marc B., 51, 149<br />

Landini, Linda, 132<br />

Landry, Daniel L., 139<br />

Lanza, Gaetano A., 91<br />

Latrella, Margaret, 140<br />

Latsios, G., 124, 128<br />

Lavange, L., 65<br />

Lawrence, Joy, 132<br />

Lawson, Andrew B., 134<br />

Lazarevic, Gordana, 120<br />

Lazar, Jason, 119, 127, 128<br />

Lazich, Ivana, 99<br />

Laz, Tabassum H., 95, 102<br />

Lazzari, Pierangelo, 87, 88<br />

Lebreiro, Ana, 135<br />

Ledezma, Mateo Levine, 89<br />

Lee, James, 109, 111<br />

Lee, John S., 132<br />

Lee, Jong Y., 123, 132<br />

Lee, Mary S., 132<br />

Lee, Sang‐Hak, 119<br />

Lee‐Son, Kathy K. Y., 87<br />

Lefebvre, Patrick, 110, 131<br />

Leiba, Adi, 95<br />

Leibovitz, Eyal, 124<br />

Leighton, Harmony, 116<br />

Leitão, Maria Fátima, 135<br />

Lembo, Giuseppe, 134, 135<br />

Leone, Aurelio, 95, 132<br />

Leoni, Simona, 95<br />

Leon‐Muñoz, Luz, 95<br />

Levine, Benjamin D., 142<br />

Levine, Robert, 118<br />

Levin, Linda, 106<br />

Levy, Bernard I., 99<br />

Levy, Daniel, 61, 78, 79, 96, 117, 150<br />

Levy, Pavel J., 117<br />

Levy, Phillip, 107, 141<br />

Levy, Phillip D., 93<br />

Lewin, Andrew, 115<br />

Lex, Lora, 133<br />

Liakos, M., 94<br />

Lian, Jean, 122<br />

Lieber, Ari, 126, 128<br />

Lieber, Ari L., 99<br />

Li, Hewang, 123<br />

Lijnen, Paul J., 135<br />

Li, Li, 122<br />

Lillestol, Michael, 98<br />

Lima, Jr., Emilton, 87<br />

Lima, Leandra Gonçalves, 132<br />

Lima, Nereida K. C., 143<br />

Lima, Nereida K. Costa, 132<br />

Limdi, Nita A., 42<br />

Limor, Rona, 100<br />

Lindholm, Lars‐Hjalmar, 93<br />

Lindi, Nita A., 150<br />

Lioni, L., 66, 122<br />

Lioudaki, Eirini, 100<br />

Li, Peng, 118, 126, 144<br />

Littlejohn, Thomas, 109, 111<br />

Littman, Stephen, 127<br />

Liu, Chunyu, 117<br />

Liu, In Lu, 67<br />

Liu, Tianh, 150<br />

Liu, Tianhu, 53<br />

Li, Wei, 114, 115<br />

Lloyd, Eric, 78<br />

Lobo, Romulo R., 143<br />

Logan, Alexander G., 132<br />

Loide, Barbosa, 137<br />

Lo, Joan C., 106<br />

Long, Laura, 141<br />

Long, Mark S., 132<br />

Lopez‐Garcia, Esther, 95<br />

Lorenzo, Sonia, 99, 131<br />

Lovic, Dragan, 120<br />

Lowenstein, Charles J., 59, 150<br />

Lucas, Caridad Turpin, 88, 109, 129<br />

Lucas, Stephanie, 90<br />

Lu, Chunzeng, 116, 126<br />

Luepke, Erik, 88, 109, 129<br />

Lu, Fei, 116, 126<br />

Luo, Jianfang, 53, 150<br />

Luo, Jiangming, 135<br />

Luo, Yingjin, 123<br />

Lurbe, Empar, 101<br />

Luther, James M., 59, 150<br />

Lu, Yee, 88<br />

Lyass, Asya, 96<br />

Lyn, Deborah, 107<br />

Lyutikova, L. N., 143<br />

M<br />

Maa, Jen‐Fue, 96, 115, 138<br />

Macdonald, Helen M., 137<br />

MacDonald, Patricia, 100<br />

MacDonald, Thomas, 112<br />

Macedo, Espiga, 138<br />

Machida, Maiko, 99<br />

Maciel, Maria Julia, 135<br />

MacIntyre, I., 121<br />

Maciosek, Michael V., 89<br />

Madede, T., 96<br />

Madruga, Felipe, 105<br />

Magarik, Jordan A., 102<br />

Magid, David J., 106<br />

Magness, Ronald, 142<br />

Mahina, Tatiana K., 108<br />

Mahon, Jeffrey L., 141<br />

Mahon, J. L., 89<br />

Maisaidi, M., 130<br />

174


Author Index<br />

Makani, Harikrishna, 107, 110<br />

Mancia, G., 130<br />

Mancia, Giuseppe, 75, 150<br />

Mancinelli, Lucia, 107, 120<br />

Manning, Alexis, 138<br />

Mann, Samuel J., 49, 111, 150<br />

Manolis, Athanasios, 136<br />

Manolis, Athanasios J., 75, 150<br />

Maraj, Ilir, 127<br />

Marasi, Gianluigi, 87, 88<br />

Marek, George, 100<br />

Margolis, Karen, 61<br />

Margolis, Karen L., 89, 106<br />

Marin, Elena, 92, 98<br />

Mark, Allyn L., 77, 80, 150<br />

Marquez, David X., 138<br />

Marquis, A., 65<br />

Martell, Nieves, 133<br />

Martinez, Cristina, 91, 92, 98<br />

Martínez, María M., 129<br />

Martinez, Marie F., 89<br />

Martinez, Santos J., 88<br />

Martin, Fernando L., 116<br />

Martins, Helia, 135<br />

Marzilli, Mario, 116, 126<br />

Mascio, Giada, 134, 135<br />

Masharani, Umesh, 98<br />

Masica, Andrew, 94<br />

Masuo, Kazuko, 138<br />

Matei, Ana Maria, 91, 99<br />

Materson, Barry J., 71, 150<br />

Mathur, Vandana, 107<br />

Matsell, Douglas G., 87<br />

Matsuda, Hirohisa, 59<br />

Matsumura, Yasuo, 59<br />

Mattingly, Phillip G., 142<br />

Mattson, David L., 72, 150<br />

Mavimbe, C., 96<br />

Mavrogeni, Helen, 100<br />

McCoy, Connie E., 106<br />

McCrory, Mark A., 103<br />

McDonnell, Barry J., 128<br />

McEniery, Carmel M., 95, 128<br />

McInnes, Gordon, 112<br />

McIsaac, Warren, 132<br />

McKie, Paul M., 47<br />

McManus, Chris, 105<br />

McManus, Richard J., 63, 150<br />

McRae, Steven, 100<br />

Medvegy, Mihaly, 134<br />

Meier, Rhonda L., 142<br />

Meijide, Luis, 98<br />

Melander, Olle, 143<br />

Melino, Michael, 109, 111<br />

Mellen, Philip, 139<br />

Mendelowitz, David, 142<br />

Merchant, Nadya, 92, 110<br />

Merenich, John, 81, 150<br />

Mesas, Arthur E., 95<br />

Mesirov, Claire, 140<br />

Messerli, Franz, 66<br />

Messerli, Franz H., 64, 65, 87, 93,<br />

107, 110, 117, 150<br />

Mestek, Michael L., 92<br />

Mete, Mihriye, 90<br />

Meyer, Peter M., 47, 113<br />

Michaelides, A., 91<br />

Miguel, Robinson, 142<br />

Mijalkovic, Dragan, 116<br />

Mikhailidis, Dimitri P., 100<br />

Miliou, A., 124<br />

Miskulin, Dana, 115<br />

Mitsnefes, Mark, 106<br />

M<strong>of</strong>fatt, Steven M., 133<br />

Mohammad, Saklayen, 122<br />

Mohyeldin, Yousri A., 142<br />

Mojon, Artemio, 60, 97, 98, 99, 108,<br />

110, 114, 121, 129, 131<br />

Molitch, Mark E., 74, 150<br />

Moñivas, Vanesa, 96<br />

Monsalvo, M. L., 140<br />

Monteiro, Agostinho, 138<br />

Moore, Michael, 89<br />

Moore, Michael A., 89<br />

Mora, Carmen, 95<br />

Moreira, Nadia, 135<br />

Moreno, Carlos, 91<br />

Moreno, Jennifer, 127<br />

Moriguti, Julio C., 143<br />

Moriguti, Júlio Cesar, 132<br />

Morimoto, Ryo, 67<br />

Morishita, Masako, 65<br />

Morita, Kiyoshi, 122<br />

Mori, Tatsuhiko, 59<br />

Morris, Ken, 140<br />

Morris, Martha Clare, 138<br />

Moschouris, Panagiotis M., 119<br />

Mota, Victoria, 129<br />

Mounier‐Vehier, Claire, 92, 127<br />

Mousa, Tarek M., 116<br />

Moya, Ana, 97, 98, 99, 121<br />

Mpafakis, I., 92, 102, 126<br />

Mpekiari, Eleni, 99<br />

Mugellini, Amedeo, 87, 88<br />

Muiesan, Maria Lorenza, 91<br />

Munnery, Iain, 128<br />

Munnery, Margaret M., 128<br />

Munroe, Patricia, 78<br />

Munroe, Patricia B., 79<br />

Munshi, Mohamed, 127<br />

Myers, Martin, 136<br />

Myshkina, Vera L., 108<br />

N<br />

Nadim, Mitra, 67<br />

Nadkarni, Girish, 117<br />

Nadkarni, Girish N., 93, 117<br />

Nakamura, Yoshikazu, 117<br />

Naqvi, Syed U., 117<br />

Narkiewicz, Krzyszt<strong>of</strong>, 75, 150<br />

Nasothimiou, Efthimia G., 134<br />

Nasser, Samar A., 93<br />

Nastac, Iulian, 128<br />

Natale, Francesco, 123<br />

Nautiyal, Amit, 119<br />

Navar, L. Gabriel, 52, 77, 151<br />

Navarro‐Ibáñez, Vicente, 90<br />

Naveen, Saxena, 102<br />

Nelson, S. A. E., 89<br />

Nelson, Sigrid A., 141<br />

Nesbitt, Shawna D., 62, 151<br />

Neumann, Claas L., 133<br />

Neutel, Joel M., 54, 138, 151<br />

Newton‐Cheh, Christopher, 78<br />

Nguyen, Phuong‐son, 132<br />

175


Author Index<br />

Nicholas, Joyce S., 134<br />

Nicholas, Susanne B., 47, 151<br />

Nichols, Wilmer W., 115<br />

Nieto, Javier, 95<br />

Nobre, Fernando, 143<br />

Nomura, Akikazu, 99<br />

Norsk, Peter, 78<br />

Notario, Patricia M., 123<br />

Novack, Victor, 103<br />

Nov, Ori, 103<br />

Nuñez, Ana Galdamez, 88, 129<br />

Nylen, Eric, 136<br />

O<br />

Obasare, Edinrin Rae, 127<br />

O’Brien, Eoin, 56, 151<br />

O’Connor, Patrick, 61<br />

O’Connor, Patrick J., 89, 106<br />

O’Donnell, Jennifer, 141<br />

Odusan, Olatunde, 97<br />

Oefelein, Michael, 139<br />

Ogedegbe, Gbenga, 45, 49, 63, 90,<br />

151<br />

Ogihara, Toshio, 138<br />

Ogunsemi, Olawale, 97<br />

Ogura, Toshihiko, 130<br />

Ohishi, Mitsuru, 95, 121<br />

Okada, Yoshiyuki, 142<br />

Okafor, H., 118<br />

Okayama, Masanobu, 117<br />

Okerson, Ted, 139<br />

Oliva, Raymond, 99<br />

Oliveras, Anna, 133<br />

Onishi, Miyuki, 95, 121<br />

Ono, Yoshikiyo, 67<br />

Onuigbo, Nwamaka, 128<br />

Oparil, Suzanne, 53, 65, 78, 88, 103,<br />

105, 109, 111, 118, 126, 138, 144,<br />

151<br />

Orak, John K., 101<br />

Oron, Yoram, 100<br />

Orynchak, Mariya A., 116, 119<br />

Osmond, Peter J., 111, 128<br />

Otero, Alfonso, 97, 111, 121, 131<br />

Owen, E. L., 97<br />

P<br />

Palaciao, Ryan, 116<br />

Palermo, Lisa, 61<br />

Paletas, Konstantinos, 99<br />

Pandey, Kailash N., 117<br />

Panjabi, Sumeet, 89, 141<br />

Pan, Nan, 135<br />

Pannu, Varinderpal, 100<br />

Panza, Julio A., 65, 151<br />

Papadakis, John A., 100<br />

Papademetriou, V., 91, 92, 124<br />

Papademetriou, Vasilios, 71, 94, 96,<br />

105, 136, 151<br />

Papagiannis, Nikolaos V., 119<br />

Papaioannou, T., 102<br />

Papapostolou, Vasileios, 132<br />

Papst, Cheraz Cherif, 98, 112, 139<br />

Paran, Esther, 103<br />

Parati, Gianfranco, 63<br />

Paredes‐Galan, Emilio, 120<br />

Parikh, Neal S., 111<br />

Parikh, Samip J., 47<br />

Parisé, Hélène, 110, 131<br />

Park, Chang‐Bum, 111, 116<br />

Parker, Emily D., 106<br />

Parker, Karen, 124<br />

Park, Jae Hong, 119<br />

Park, Jeong‐Euy, 94<br />

Park, Jinhee, 122, 133<br />

Patel, Rinkesh, 127<br />

Patel, Seema, 116<br />

Pavlidis, Athinodoros, 111<br />

Pavlyuk, Evhenia A., 133<br />

Pearson, Thomas A., 44, 151<br />

Pedrinelli, Roberto, 116<br />

Pego, Guilherme Augusto<br />

Mariano, 135<br />

Pego, João Bernardo, 135<br />

Peixoto, Aldo J., 60, 73, 151<br />

Pelazza, Bruno B., 123<br />

Pemba, Senga, 141<br />

Pencina, Michael, 96<br />

Perez de Lis, Jesus, 111<br />

Pérez, Javier, 129<br />

Pérez, Miguel Palencia, 116<br />

Perkins, Nancy, 136<br />

Peroz, Julie, 99, 126, 128<br />

Persson, Mats, 93<br />

Peterson, Jessica A., 100<br />

Petry, Nancy M., 136<br />

Phillips, Robert A., 40, 61, 126, 151<br />

Pickering, Thomas, 90<br />

Pierce, Caleb, 103<br />

Piñeiro, Luis, 121<br />

Pinol, Ramon, 142<br />

Pisoni, Roberto, 88, 108, 138<br />

Pi‐Sunyer, F. Xavier, 58, 151<br />

Pittaras, Andreas, 136<br />

Pitt, Bertram, 71, 107, 151<br />

Plavnik, Frida Liane, 102<br />

Podjarny, Eduardo, 131<br />

Pogue, Velvie A., 74, 151<br />

Pollock, David M., 51, 151<br />

Pollock, Norman K., 47<br />

Polonia, Jorge, 96, 129, 134<br />

Polonia, Jorge J., 137<br />

Popov, E. G., 143<br />

Potapova, Galina N., 143<br />

Poulakis, M., 124, 126<br />

Pousa, Lorenzo, 99, 111<br />

Pratt, Howard J., 151<br />

Pratt, J. Howard, 59<br />

Pressler, Susan, 90, 115<br />

Primak, Galina F., 133<br />

Priore, Emanuela Lo, 123<br />

Pritchard, Sheila L., 87<br />

Protogerou, Athanase D., 126<br />

Providência, Luis Augusto, 135<br />

Pruden, James, 140<br />

Pruette, Cozumel S., 101<br />

Pstay, Bruce M., 79<br />

Punzi, Henry A., 64, 96, 115, 152<br />

Purakal, John, 141<br />

Puri, Nitin, 66, 122<br />

Purkayastha, Das, 109, 113, 114<br />

Pyun, Wook Bum, 119<br />

Pyun, Wook‐Bum, 118, 120<br />

Q<br />

Quéré, Stéphane, 92, 127, 140<br />

R<br />

176


Author Index<br />

Rabelink, Ton J., 93<br />

Raheja, Prafull, 59<br />

Rahman, Mahboob, 60<br />

Rahman, Mahbubur, 95, 102<br />

Rahman, Syed T., 110<br />

Raij, Leopoldo, 52, 152<br />

Rajagopalan, Sanjay, 65<br />

Rajagopal, Desikan, 92<br />

Rajpal, Minesh, 111, 128<br />

Rakugi, Hiromi, 95, 121, 138<br />

Ramamurthy, Priyanka, 133<br />

Ram, C. Venkata S., 40, 73, 152<br />

Rana, Hamza, 117<br />

Ranieri, Alessandro, 123<br />

Rantamaula, Laura, 114<br />

Rapoport, Jayson, 123<br />

Rarra, Vagia, 134<br />

Rasgon, Scott, 67<br />

Rasgon, Scott A., 89, 108<br />

Rash, Carla J., 136<br />

Ratner, Robert E., 90<br />

Ravussin, Eric, 137<br />

Rebelo, Irene, 138<br />

Rechtman, Ehud, 103<br />

Reddy, Maithri, 90<br />

Reddy, Podduturu S., 90<br />

Reddy, Sushma, 90<br />

Reid, David M., 137<br />

Rekovets, Oksana L., 133<br />

Reyes, Andres, 92, 98<br />

Rey, Jose Manuel Del, 98<br />

Reynolds, Kristi, 131, 140<br />

Rezzani, Rita, 122<br />

Rho, Tae‐Ho, 88<br />

Rice, Kenneth, 78<br />

Rice, Kenneth M., 79<br />

Rich, Steven, 116<br />

Rieken, Eike M., 133<br />

Rim, Se‐Joong, 118, 119, 120<br />

Rios, Maria T., 98, 111<br />

Ríos, María T., 129<br />

Rippe, James, 82, 152<br />

Roberts, A., 115<br />

Roberts, Andrew, 78, 112<br />

Rocchini, Albert, 87<br />

Rodriguez, Arantxa, 47, 91, 92, 98,<br />

110<br />

Rodriguez‐Artalejo, Fernando, 95<br />

Rodríguez‐Artalejo, Fernando, 120<br />

Rodriguez‐Pascual, Carlos, 120<br />

Rogelio, Gregorio G., 139<br />

Roig‐Espert, Belén, 90<br />

Rojas, Jose M., 127<br />

Rollins-Hairston, Aisha, 107<br />

Roman, Mary J., 90<br />

Romero, Jorge, 107, 110<br />

Rosa, César S., 123<br />

Rosenthal, Talma, 100, 105, 152<br />

Rosman, Yosi, 103<br />

Rossi, Filippo, 137<br />

Rothwell, Peter M., 56<br />

Rousos, D., 124, 128<br />

Roussias, Leonidas, 106<br />

Roussias, Leonidas G., 134<br />

Routledge, Faye S., 131<br />

Rudich, Assaf, 103<br />

Rughani, Govind, 102<br />

Ruilope, Luis M., 60, 67, 70, 93, 96,<br />

105, 123, 133, 134, 152<br />

Ruilope, Luis Maria, 101, 102<br />

Ruiz, Santiago Garcia, 88, 109<br />

Russell, Holly Ann, 123<br />

Russell, Marie, 90<br />

Russo, Andrea, 136<br />

Russo, Kristen M., 123<br />

Russo, Maria Giovanna, 123<br />

Ryabikina, G. V., 143<br />

Ryan, Michael J., 23, 76, 152<br />

Ryu, Sung‐Kee, 118, 119, 120<br />

S<br />

Saban‐Ruiz, Jose, 47, 91, 92, 98, 110<br />

Sabharwal, Manpreet S., 93, 117<br />

Saelens, Brian E., 106<br />

Saez, Ana Osa, 116<br />

Safar, Michel E., 99, 112, 126, 128<br />

Sakata, Koji, 96<br />

Salciccioli, Louis, 127, 128<br />

Saldaña, Manuel Aguilera, 88, 129<br />

Saleh, Tarek M., 92<br />

Salgado, Jose L., 99, 131<br />

Salvi, Paolo, 128<br />

Samad, Zahid, 118<br />

Sampson, U., 118<br />

Samuel, Rita, 109<br />

Sanada, Hironobo, 123<br />

Sanchez, Luis, 67<br />

Sanchez, Olivia, 91, 98, 110<br />

Sander, Gary E., 127<br />

Sandu, Oana, 128<br />

Sangaralingham, S. Jeson, 47<br />

Sansone, Torry Mark, 140<br />

Santos, Jose Nobre, 134<br />

Santos, Rosa M., 138<br />

Sanz, Antonio Salvador, 116<br />

Sarafidis, Pantelis A., 99<br />

Sarda, Sujata P., 133<br />

Sarigianni, Maria, 99<br />

Sarmento, Priscilla Lopes, 102<br />

Sarzani, Riccardo, 107, 120, 133<br />

Sas, David J., 101<br />

Satoh, Fumitoshi, 67<br />

Saul, Sara, 116<br />

Saul, Sara M., 144<br />

Saunders, Elijah, 40, 152<br />

Sauter, Kathleen, 140<br />

Sautin, Yuri Y., 100<br />

Savopoulos, Christos, 111<br />

Schiffrin, Ernesto L., 72, 152<br />

Schmidlin, Olga, 98<br />

Schmieder, Roland E., 67, 152<br />

Schneider, Edward, 88<br />

Schneider, Stephanie C., 90<br />

Schoenthaler, Antoinette, 45, 152<br />

Schreiner, Susan, 90<br />

Schulz, Egbert G., 133<br />

Schwartz, Ann, 61<br />

Schwartz, Faina, 117<br />

Schwartz, Joseph, 90<br />

Schwartzman, Michal L., 66<br />

Scisney‐Matlock, Margaret, 90, 115<br />

Scott, Graham A., 141<br />

Sebastian, Anthony, 98<br />

Sechi, Leonardo A., 59, 88, 136<br />

Secombes, Karen R., 137<br />

177


Author Index<br />

Segev, Shlomo, 103<br />

Segura, Julian, 67, 93, 96, 101, 102,<br />

105, 123, 134<br />

Segura, Julián, 133<br />

Selassie, Anbesaw, 130<br />

Sen, Amanda, 90, 115<br />

Seo, Hye‐Sun, 118, 120<br />

Serdengecti, Kamil, 121<br />

Seredyuk, Nestor M., 92, 119<br />

Seredyuk, Vitaliy N., 92<br />

Sergakova, L. M., 143<br />

Serio, Ilaria, 95<br />

Severin, Thomas, 98, 139<br />

Seyoum, Berhane, 107<br />

Sgourakis, Panagiotis D., 119<br />

Shaftman, Stephanie, 110<br />

Shah, Arpit, 110<br />

Shahawy, Mahfouz El, 93, 94<br />

Shah, Hardik K., 123, 132<br />

Shah, Niren K., 115<br />

Shanks, Amy M., 141<br />

Shapiro, Joseph I., 142<br />

Sharabi, Yehonatan, 103<br />

Sharma, Abhishek, 128<br />

Shatat, Ibrahim F., 101<br />

Shea, J., 113<br />

Sheremeta, Oleg M., 119<br />

Sheriff, Helen, 136<br />

Sherrill, Beth, 141<br />

Sherwood, Andrew, 131<br />

Sherwood, Nancy E., 106<br />

Shibata, Shigeki, 142<br />

Shi, Jiaxiao, 67<br />

Shi, Jiaxiao M., 108<br />

Shilova, Victoria Y., 142<br />

Shimada, Kazuyuki, 102, 110, 118,<br />

132<br />

Shimaoka, Izumi, 121<br />

Shimizu, Motohiro, 110<br />

Shin, Hwashin H., 129<br />

Shin, Sung‐Hee, 118, 120<br />

Shi, Victor, 101<br />

Shlyakhto, Evgeny V., 87<br />

Shojaee, Ali, 96, 115, 138<br />

Shoval, Ishay, 123<br />

Shrabi, Yonatan, 124<br />

Shull, Cyndi, 141<br />

Shustov, Sergey B., 139<br />

Sica, D., 115<br />

Sica, Domenic, 67, 78, 112<br />

Sica, Domenic A., 40, 67, 70, 152<br />

Siciliano, Alessandro, 123<br />

Silva, Jose A., 96, 137<br />

Silverman, Angela, 90<br />

Sim, John, 67<br />

Sim, John J., 108<br />

Simmons, Debra, 61, 89<br />

Simonyi, Gabor, 134<br />

Simpson, William G., 137<br />

Sinaiko, Alan R., 106<br />

Sindel, Sukru, 97<br />

Sineiro, Elvira, 99, 121<br />

Sion‐Vrdy, Netta, 103<br />

Sirenko, Yuriy M., 133<br />

Siu, Kin Lung, 122<br />

Skoumas, I., 135<br />

Skrypnyk, Nadiya V., 119<br />

Slama, Gerard, 99<br />

Smith, Albert V., 79<br />

Smith, Jr., Sidney, 81<br />

Smith, Rick, 88<br />

Smith, Ronald D., 89<br />

Smith, Steven M., 115<br />

Smith, William, 139<br />

Smyrnioudis, Nikolaos E., 119<br />

Soboleva, Galina M., 108<br />

Sodhi, Komal, 66<br />

Sohn, Il‐Suk, 111, 116<br />

Solari, D., 130<br />

Solar‐Yohay, Susan, 101<br />

Soldatos, N., 96<br />

Sole, Ricardo M. Cabrera, 88, 109,<br />

129<br />

Soriano, Joaquin Rueda, 116<br />

Sorrentino, Matthew, 40, 152<br />

Sos, Thomas A., 56, 152<br />

Sousa, Alexandra, 135<br />

Sowers, James R., 74, 153<br />

SperlHillen, JoAnn M., 89<br />

Sridharan, Kanaka, 113, 114<br />

Srikakarlapudi, Sirisha, 111, 128<br />

Srinivasan, Sathanur R., 94<br />

Staffileno, Beth A., 138<br />

Stagni, Barbara, 95<br />

Stallmann-Jorgensen, Inger, 47<br />

Stasiv, Yuri, 107<br />

Stauffer, Brian L., 92<br />

Stefanadi, E., 66<br />

Stefanadis, C., 61, 66, 91, 92, 94, 96,<br />

102, 122, 124, 126, 128, 135<br />

Steigerwalt, Susan, 90, 115<br />

Stergiou, George S., 105, 106, 134<br />

Sterling, Kevin A., 127<br />

Stern, Naftali, 100<br />

Steven, Bendel D., 109<br />

Stevens, Lesley A., 68, 153<br />

Strano, Talita R., 87<br />

Strimike, Carolyn, 140<br />

Struthers, Allan D., 66, 153<br />

Sturgeon, Kathleen M., 136, 138, 144<br />

Stylianou, Mario, 90<br />

Suárez, Carmen, 133<br />

Suleymanlar, Gultekin, 121<br />

Sun, B., 97<br />

Sun, Fengzhu, 117<br />

Svetkey, Laura P., 49, 153<br />

Symonides, Bartosz, 138<br />

Syros, George, 93<br />

Syrseloudis, D., 92, 102, 124, 128<br />

Szalai, Alexander J., 103<br />

Szendro, Gabriel, 103<br />

T<br />

Tabassome, Simon, 92, 127<br />

Taddei, Stefano, 91<br />

Takahashi, Toru, 122<br />

Takechi, Shigeru, 99<br />

Takeya, Yasushi, 95, 121<br />

Taler, Sandra J., 73, 153<br />

Tamarit‐García, Juan José, 90<br />

Tangney, Christy, 138<br />

Tao, Jun, 128<br />

Tao, Ting, 53, 153<br />

Tasic, Ivan, 116, 120<br />

Tatara, Yuji, 95, 121<br />

178


Author Index<br />

Tatsis, I., 92, 124<br />

Taylor, Addison A., 47, 64, 153<br />

Taylor‐Zapata, Perdita, 101<br />

Teixeira, Tiago, 134<br />

Tejera, Eduardo, 138<br />

Tello, Susana, 47, 91, 92, 98, 110<br />

Terrone, Deborah, 140<br />

Tewksbury, Duane A., 135<br />

Thangaratnavel, Revathy, 127<br />

Thies, Frank, 137<br />

Thomopoulos, C., 92, 96, 122, 128<br />

Thopy, Amanda, 106<br />

Thrun, Jan‐Marc Schmidt, 133<br />

Tiawana, Simrandeep K., 89<br />

Tiktin, Margaret, 61<br />

Tisler, Andras, 132<br />

Titze, Jens, 77, 80, 153<br />

Tobe, Sheldon W., 54, 136, 153<br />

Tobin, Jonathan, 90<br />

Tomiyama, Hir<strong>of</strong>umi, 130<br />

Tong, Xin, 129<br />

Tonne, Jason M., 116<br />

Topouchian, Jirar, 128<br />

Torrente‐Carballido, Marta, 120<br />

Torro, Isabel, 101<br />

Toto, Robert, 60, 121<br />

Toto, Robert D., 74, 82, 122<br />

Touyz, Rhian M., 43, 65, 153<br />

Townsend, Raymond R., 46, 127,<br />

139, 153<br />

Tsapas, Apostolos, 99<br />

Tsiachris, D., 92, 124, 128<br />

Tsioufis, C., 66, 91, 92, 96, 102, 122,<br />

124, 126, 128<br />

Tsioufis, Costas, 96<br />

Tsounis, Dimitrios, 100, 115<br />

Turgan, Cetin, 97<br />

Turk, Aquilla S., 102<br />

Tutor, Elena, 91, 98<br />

Tyszkiewicz, Jerzy T., 138<br />

Tzamouranis, Dimitrios, 134<br />

Tzamouranis, Dimitris, 105<br />

Tziomalos, Konstantinos, 111<br />

U<br />

Uehara, Ritei, 117<br />

Ugalde, Arturo, 98<br />

Umans, Jason G., 90<br />

Underwood, P., 97<br />

Urbina, Elaine M., 106<br />

Uribarri, Jaime, 128<br />

Utas, Cengiz, 121<br />

V<br />

Vakalyuk, Igor P., 92, 116<br />

Vakalyuk, Iryna I., 116, 119<br />

Van Buren, Peter N., 121, 122<br />

Vandervoort, Margaret K., 141<br />

Vandervoort, M. K., 89<br />

van Duijn, Cornelia M., 79<br />

van Duin, Cornelia, 78<br />

Vanella, Luca, 66, 122<br />

VanGundy, Tiffany B., 142<br />

van Pelt, Jos F., 135<br />

Vansomphone, Southida S., 140<br />

Varis, Juha, 114<br />

Vasan, Ramachandran S., 117<br />

Vasan, R. S., 96<br />

Vaschilko, Alla S., 133<br />

Vassalotti, Joseph A., 68, 153<br />

Vecchione, Carmine, 134<br />

Veerabhadrappa, Praveen, 136, 138,<br />

144<br />

Velhas, Moncho, 129<br />

Venner-Jones, Kinda, 127<br />

Veronesi, Maddalena, 93<br />

Verri‐Junior, Waldiceu A., 143<br />

Vette, Alan, 129<br />

Victor, Ronald G., 40, 67, 153<br />

Vigdorchik, Alexey V., 112<br />

Vigil, Luis, 133<br />

Vilches‐Moraga, Arturo, 120<br />

Villafruela, Juanjo, 91<br />

Villar, Van Anthony M., 122, 123<br />

Vinereanu, Dragos, 143<br />

Vinita, Srivastava, 102<br />

Vittingh<strong>of</strong>f, Eric, 61<br />

Vives, Miguel Angel Arnau, 116<br />

Vongpatanasin, Wanpen, 59, 142<br />

Vrentzos, George E., 100<br />

Vyssoulis, Gregory, 61, 94, 135<br />

W<br />

Wagner, C., 110<br />

Wagner, C. Shaun, 130, 134<br />

Wang, Guijing, 137<br />

Wang, Hongyu, 53, 153<br />

Wang, Jackson, 94<br />

Wang, Si‐Tien, 133<br />

Wang, Zhijun, 59<br />

Ward, Rachel, 124<br />

Watkins, Shannon B., 144<br />

Waverczak, William F., 96, 115, 138<br />

Webb, David J., 65, 153<br />

Webb, D. J., 97, 121<br />

Webb, R. Clinton, 43, 153<br />

Weber, M. A., 115<br />

Weber, Michael, 78<br />

Weber, Michael A., 40, 112, 153<br />

Weder, Alan B., 42, 73, 141, 154<br />

Weil, Brian R., 92<br />

Weinberger, Myron H., 47, 154<br />

Weir, Matthew R., 74, 90, 96, 115,<br />

154<br />

Wei, Robert, 133<br />

Weitzman, Richard, 98, 113, 114<br />

Welch, Robert, 141<br />

Welch, W. Pete, 101<br />

Wells, Ann M., 90<br />

Wever‐Pinzon, Omar, 107<br />

Whalen, J. J., 113<br />

Whaley‐Connell, Adam, 68, 154<br />

Whelton, Andrew, 66, 100, 154<br />

White, W. B., 65, 115<br />

White, William B., 56, 58, 63, 75, 78,<br />

109, 112, 136, 154<br />

Wilbur, JoEllen, 138<br />

Wilcox, C., 91<br />

Wilkinson, Ian B., 46, 95, 128, 154<br />

Williams, Bryan, 56, 61, 74, 154<br />

Williams, Eric, 141<br />

Williams, G., 97<br />

Williams, Gordon H., 40, 154<br />

Williams, J., 97<br />

Williams‐Johnson, Jean, 141<br />

Williamson, Sheara, 136<br />

Williamson, Sheara M., 144<br />

179


Author Index<br />

Williamson, Sheara T., 138<br />

Williams, Ron, 129<br />

Wilson, Peter F., 154<br />

Wilson, Peter W. F., 44, 96<br />

Winborne, Courtland, 124<br />

Winkler, Amber, 141<br />

Wohlgemuth, William K., 131<br />

Wolak, Talya, 103<br />

Wolf, Philip A., 96<br />

Wong, Cindy J., 141<br />

Wong, C. J., 89<br />

Wong, Nathan D., 44, 154<br />

Wood, Adrian D., 137<br />

Wright, Richard F., 109<br />

Wymer, David, 100<br />

X<br />

Xavier, Ana C., 100<br />

Xing, Dongqi, 103, 118, 126, 144<br />

Y<br />

Yadao, Anthony, 139<br />

Yakovlev, Sergey A., 108<br />

Yamamoto‐Hanasaki, Hiroko, 121<br />

Yamashina, Akira, 130<br />

Yang, Qiong, 117<br />

Yang, Wenya, 101<br />

Yang, Yu, 47, 123<br />

Yang, Zhen, 128<br />

Yano, Yuichiro, 96, 102, 118<br />

Yan, Shi Du, 135<br />

Yatsyshyn, Natalya G., 97<br />

Yatsyshyn, Roman I., 97<br />

Yokota, Naoto, 114<br />

Yoon, Esther, 87<br />

Yoo, Sandra A., 90<br />

Young, Joseph D., 61<br />

Youn, Ho‐Joong, 88<br />

Younis, Firas, 100<br />

Yuan, Hong, 112<br />

Yu‐Isenberg, Kristina, 110<br />

Z<br />

Zacker, Christopher, 141<br />

Zager, Philip, 115<br />

Zajicek, Anne, 101<br />

Zamadio, Stacy, 142<br />

Zand, Martin S., 60, 154<br />

Zazulina, Antonina Y., 112<br />

Zeniodi, Maria‐Helen, 100<br />

Zhang, J., 140<br />

Zhang, Jack, 112, 139<br />

Zhang, Jie, 141<br />

Zhang, Shiling, 107<br />

Zhang, Wei, 103, 118<br />

Zhang, Yanrong, 47, 97<br />

Zhang, Yi, 112, 126, 128<br />

Zhang, Ying, 101<br />

Zhao, Yumin, 105, 130<br />

Zhong, Wei, 144<br />

Zhu, Haidong, 47<br />

Zoppi, Annalisa, 87, 88<br />

Zou, Guang Y., 141<br />

Zou, G. Y., 89<br />

180


Hilton New York Floor Plans<br />

Second Floor<br />

181


Hilton New York Floor Plans<br />

Thrid Floor<br />

182


Hilton New York Floor Plans<br />

Fourth Floor Concourse<br />

183


Notes<br />

184


Tekamlo (aliskiren and amlodipine) tablets<br />

Initial U.S. Approval: 2010<br />

BRIEF SUMMARY: Please see package insert for full prescribing information.<br />

WARNING: AVOID USE IN PREGNANCY<br />

When pregnancy is detected, discontinue Tekamlo as soon as possible. Drugs<br />

that act directly on the renin-angiotensin-aldosterone system can cause injury<br />

and even death to the developing fetus. [See Warnings and Precautions (5.1)<br />

and Use in Specific Populations (8.1)].<br />

1 INDICATIONS AND USAGE<br />

Tekamlo is indicated for the treatment <strong>of</strong> hypertension, alone or with other antihypertensive<br />

agents.<br />

Initial Therapy<br />

Use Tekamlo as initial therapy in patients who are likely to need multiple drugs<br />

to achieve their blood pressure goals.<br />

Base the choice <strong>of</strong> Tekamlo as initial therapy on an assessment <strong>of</strong> potential benefits<br />

and risks.<br />

Add-On Therapy<br />

Switch a patient whose blood pressure is not adequately controlled with aliskiren<br />

alone or amlodipine besylate (or another dihydropyridine calcium channel<br />

blocker) to combination therapy with Tekamlo.<br />

Replacement Therapy<br />

Tekamlo may be substituted for its titrated components.<br />

Patients with moderate or severe hypertension are at a relatively high risk for<br />

cardiovascular events (such as strokes, heart attacks, and heart failure), kidney<br />

failure, and vision problems, so prompt treatment is clinically relevant. Individualize<br />

the decision to use a combination as initial therapy by weighing factors<br />

such as baseline blood pressure, the target goal, and the incremental likelihood<br />

<strong>of</strong> achieving goal with a combination compared to monotherapy. Individual<br />

blood pressure goals may vary based upon the patient’s risk.<br />

Data from the high-dose multifactorial study [see Clinical Studies (14) in the full<br />

prescribing information] provide estimates <strong>of</strong> the probability <strong>of</strong> reaching a target<br />

blood pressure with Tekamlo compared to aliskiren or amlodipine monotherapy.<br />

The figures below provide estimates <strong>of</strong> the likelihood <strong>of</strong> achieving systolic or<br />

diastolic blood pressure control with Tekamlo 300 mg/10 mg, based upon baseline<br />

systolic or diastolic blood pressure. The curve <strong>of</strong> each treatment group was<br />

estimated by logistic regression modeling. The estimated likelihood at the right<br />

tail <strong>of</strong> each curve is less reliable because <strong>of</strong> a small number <strong>of</strong> subjects with<br />

high baseline blood pressures.<br />

Figure 1: Probability <strong>of</strong> Achieving Systolic Blood Pressure (SBP)


Figure 2: Probability <strong>of</strong> Achieving Diastolic Blood Pressure (DBP)


25% (systolic) and 27% (diastolic) [see Dosage and Administration (2) and<br />

Clinical Studies (14) in the full prescribing information].<br />

4 CONTRAINDICATIONS<br />

None.<br />

5 WARNINGS AND PRECAUTIONS<br />

5.1 Fetal/Neonatal Morbidity and Mortality<br />

The use <strong>of</strong> drugs that act directly on the renin-angiotensin-aldosterone system<br />

during pregnancy can cause fetal and neonatal morbidity and death. No animal<br />

studies were conducted with Tekamlo; however, decreased fetal birth weight was<br />

observed in animal studies with aliskiren and intrauterine deaths were observed<br />

in animal studies with amlodipine. Tekamlo can cause fetal harm when administered<br />

to a pregnant woman. When pregnancy is detected, discontinue Tekamlo as<br />

soon as possible. If Tekamlo is used during pregnancy, or if a patient becomes<br />

pregnant while taking this drug, apprise the patient <strong>of</strong> the potential hazard to the<br />

fetus [see Use in Specific Populations (8.1)].<br />

5.2 Head and Neck Angioedema<br />

Aliskiren<br />

Angioedema <strong>of</strong> the face, extremities, lips, tongue, glottis and/or larynx has been<br />

reported in patients treated with aliskiren and has necessitated hospitalization<br />

and intubation. This may occur at any time during treatment and has occurred<br />

in patients with and without a history <strong>of</strong> angioedema with ACE inhibitors or<br />

angiotensin receptor antagonists. If angioedema involves the throat, tongue,<br />

glottis or larynx, or if the patient has a history <strong>of</strong> upper respiratory surgery, airway<br />

obstruction may occur and be fatal. Patients who experience these effects,<br />

even without respiratory distress, require prolonged observation, since treatment<br />

with antihistamines and corticosteroids may not be sufficient to prevent<br />

respiratory involvement. Prompt administration <strong>of</strong> subcutaneous epinephrine<br />

solution 1:1000 (0.3 to 0.5 ml) and measures to ensure a patent airway may be<br />

necessary.<br />

Discontinue Tekamlo immediately in patients who develop angioedema and do<br />

not readminister.<br />

5.3 Hypotension<br />

An excessive fall in blood pressure (hypotension) was rarely seen (0.2%) in<br />

patients with uncomplicated hypertension treated with Tekamlo in controlled<br />

trials.<br />

In patients with an activated renin-angiotensin-aldosterone system, such as volumeand/or<br />

salt-depleted patients receiving high doses <strong>of</strong> diuretics, symptomatic<br />

hypotension may occur in patients receiving renin-angiotensin-aldosterone<br />

system (RAAS) blockers. Correct these conditions prior to administration <strong>of</strong><br />

Tekamlo, or start the treatment under close medical supervision.<br />

If an excessive fall in blood pressure occurs with Tekamlo, place the patient in<br />

the supine position and, if necessary, give an intravenous infusion <strong>of</strong> normal<br />

saline. A transient hypotensive response is not a contraindication to further<br />

treatment, which usually can be continued without difficulty once the blood<br />

pressure has stabilized.<br />

5.4 Risk <strong>of</strong> Myocardial Infarction or Increased Angina<br />

Rarely, initiation or change to the dose <strong>of</strong> a calcium channel blocker has resulted<br />

in the development <strong>of</strong> documented increased frequency, duration or severity<br />

<strong>of</strong> angina or acute myocardial infarction, particularly in patients with severe<br />

obstructive coronary artery disease. The mechanism <strong>of</strong> this effect has not been<br />

elucidated.<br />

5.5 Impaired Renal Function<br />

Tekamlo<br />

Clinical trials with Tekamlo in hypertension excluded patients with severe renal<br />

impairment.<br />

Aliskiren<br />

Clinical trials <strong>of</strong> aliskiren in hypertension excluded patients with severe renal<br />

dysfunction (creatinine 1.7 mg/dL for women and 2.0 mg/dL for men and/or<br />

estimated GFR


should be exercised when administering Tekamlo to patients with severe hepatic<br />

impairment.<br />

5.7 Patients with Congestive Heart Failure<br />

Amlodipine besylate<br />

Amlodipine (5-10 mg per day) has been studied in a placebo-controlled trial <strong>of</strong><br />

1153 patients with NYHA Class III or IV heart failure on stable doses <strong>of</strong> ACE<br />

inhibitor, digoxin, and diuretics. Follow-up was at least 6 months, with a mean <strong>of</strong><br />

about 14 months. There was no overall adverse effect on survival or cardiac<br />

morbidity (as defined by life-threatening arrhythmia, acute myocardial infarction,<br />

or hospitalization for worsened heart failure). Amlodipine has been compared to<br />

placebo in four 8-12 week studies <strong>of</strong> patients with NYHA Class II/III heart failure,<br />

involving a total <strong>of</strong> 697 patients. In these studies, there was no evidence <strong>of</strong><br />

worsened heart failure based on measures <strong>of</strong> exercise tolerance, NYHA classification,<br />

symptoms, or left ventricular ejection fraction.<br />

5.8 Renal Artery Stenosis<br />

No data are available on the use <strong>of</strong> Tekamlo or aliskiren in patients with unilateral<br />

or bilateral renal artery stenosis or stenosis <strong>of</strong> the artery to a solitary kidney.<br />

However, in studies <strong>of</strong> ACE inhibitors in hypertensive patients with unilateral or<br />

bilateral renal artery stenosis, increases in serum creatinine or blood urea nitrogen<br />

have been reported.<br />

5.9 Cyclosporine or Itraconazole<br />

Aliskiren<br />

When aliskiren was given with cyclosporine or itraconazole, the blood concentrations<br />

<strong>of</strong> aliskiren were significantly increased. Avoid concomitant use <strong>of</strong><br />

aliskiren with cyclosporine or itraconazole [see Drug Interactions (7)].<br />

6 ADVERSE REACTIONS<br />

6.1 Clinical Studies Experience<br />

The following serious adverse reactions are discussed in greater detail in other<br />

sections <strong>of</strong> the label:<br />

• Risk <strong>of</strong> fetal/neonatal morbidity and mortality [see Warnings and Precautions<br />

(5.1)]<br />

• Head and neck angioedema [see Warnings and Precautions (5.2)]<br />

• Hypotension [see Warnings and Precautions (5.3)]<br />

Because clinical trials are conducted under widely varying conditions, adverse<br />

reaction rates observed in the clinical trials <strong>of</strong> a drug cannot be directly compared<br />

to rates in clinical trials <strong>of</strong> another drug and may not reflect the rates<br />

observed in practice.<br />

Tekamlo<br />

Tekamlo has been evaluated for safety in more than 2800 patients, including 372<br />

patients for 1 year or longer.<br />

In a placebo-controlled study, there were 51% males, 62% Caucasians, 20%<br />

Blacks, 18% Hispanics, and 17% who were over 65 years <strong>of</strong> age. In this study,<br />

the overall incidence <strong>of</strong> adverse events on therapy with Tekamlo was similar to<br />

the individual components. Discontinuation <strong>of</strong> therapy due to a clinical adverse<br />

event in this study occurred in 1.7% <strong>of</strong> patients treated with Tekamlo (2.2% in<br />

the highest dose group) versus 1.5% <strong>of</strong> patients given placebo.<br />

Peripheral edema is a known, dose-dependent adverse effect <strong>of</strong> amlodipine. The<br />

incidence <strong>of</strong> peripheral edema for Tekamlo in short-term double-blind placebocontrolled<br />

studies was lower than or equal to that <strong>of</strong> the corresponding amlodipine<br />

doses.<br />

The adverse event in a placebo-controlled trial that occurred in at least 2% <strong>of</strong><br />

patients treated with Tekamlo and at a higher incidence than placebo was peripheral<br />

edema (6.2% versus 1.0%). The incidence rate <strong>of</strong> peripheral edema at high<br />

dose was 8.9%.<br />

In a long-term safety trial, the safety pr<strong>of</strong>ile <strong>of</strong> adverse events was similar to that<br />

seen in the short-term controlled trials.<br />

Aliskiren<br />

Aliskiren has been evaluated for safety in 6460 patients, including 1740 treated<br />

for longer than 6 months, and 1250 for longer than 1 year. In placebo-controlled<br />

clinical trials, discontinuation <strong>of</strong> therapy because <strong>of</strong> a clinical adverse event,<br />

including uncontrolled hypertension, occurred in 2.2% <strong>of</strong> patients treated with<br />

aliskiren versus 3.5% <strong>of</strong> patients given placebo.


Two cases <strong>of</strong> angioedema with respiratory symptoms were reported with<br />

aliskiren use in the clinical studies. Two other cases <strong>of</strong> periorbital edema without<br />

respiratory symptoms were reported as possible angioedema and resulted in<br />

discontinuation. The rate <strong>of</strong> these angioedema cases in the completed studies<br />

was 0.06%.<br />

In addition, 26 other cases <strong>of</strong> edema involving the face, hands, or whole body<br />

were reported with aliskiren use, including 4 leading to discontinuation.<br />

In the placebo-controlled studies, however, the incidence <strong>of</strong> edema involving the<br />

face, hands, or whole body was 0.4% with aliskiren compared with 0.5% with<br />

placebo. In a long-term active-controlled study with aliskiren and HCTZ arms,<br />

the incidence <strong>of</strong> edema involving the face, hands, or whole body was 0.4% in<br />

both treatment arms.<br />

Aliskiren produces dose-related gastrointestinal (GI) adverse reactions. Diarrhea<br />

was reported by 2.3% <strong>of</strong> patients at 300 mg, compared to 1.2% in placebo<br />

patients. In women and the elderly (age ≥65) increases in diarrhea rates were<br />

evident starting at a dose <strong>of</strong> 150 mg daily, with rates for these subgroups at<br />

150 mg similar to those seen at 300 mg for men or younger patients (all rates<br />

about 2%). Other GI symptoms included abdominal pain, dyspepsia, and gastro -<br />

esophageal reflux, although increased rates for abdominal pain and dyspepsia<br />

were distinguished from placebo only at 600 mg daily. Diarrhea and other<br />

GI symptoms were typically mild and rarely led to discontinuation.<br />

Aliskiren was associated with a slight increase in cough in the placebo-controlled<br />

studies (1.1% for any aliskiren use versus 0.6% for placebo). In active-controlled<br />

trials with ACE inhibitor (ramipril, lisinopril) arms, the rates <strong>of</strong> cough for the<br />

aliskiren arms were about one-third to one-half the rates in the ACE inhibitor arms.<br />

Other adverse reactions with increased rates for aliskiren compared to placebo<br />

included rash (1% versus 0.3%), elevated uric acid (0.4% versus 0.1%), gout<br />

(0.2% versus 0.1%), and renal stones (0.2% versus 0%).<br />

Single episodes <strong>of</strong> tonic-clonic seizures with loss <strong>of</strong> consciousness were<br />

reported in two patients treated with aliskiren in the clinical trials. One patient<br />

had predisposing causes for seizures and had a negative electroencephalogram<br />

(EEG) and cerebral imaging following the seizures; for the other patient, EEG and<br />

imaging results were not reported. Aliskiren was discontinued and there was no<br />

rechallenge in either case.<br />

No clinically meaningful changes in vital signs or in ECG (including QTc interval)<br />

were observed in patients treated with aliskiren.<br />

Amlodipine besylate<br />

Amlodipine (Norvasc ® ) has been evaluated for safety in more than 11,000<br />

patients in U.S. and foreign clinical trials. Other adverse events that have been<br />

reported 0.1% <strong>of</strong> patients in controlled clinical trials or under conditions<br />

<strong>of</strong> open trials or marketing experience where a causal relationship is<br />

uncertain were:<br />

Cardiovascular: arrhythmia (including ventricular tachycardia and atrial fibrillation),<br />

brady cardia, chest pain, peripheral ischemia, syncope, postural hypo -<br />

tension, vasculitis<br />

Central and Peripheral Nervous System: neuropathy peripheral, paresthesia,<br />

tremor, vertigo<br />

Gastrointestinal: anorexia, constipation, dyspepsia,** dysphagia, diarrhea, flatulence,<br />

pancreatitis, vomiting, gingival hyperplasia<br />

General: allergic reaction, asthenia,** back pain, hot flushes, malaise, pain, rigors,<br />

weight gain, weight decrease<br />

Musculoskeletal System: arthralgia, arthrosis, muscle cramps,** myalgia<br />

Psychiatric: sexual dysfunction (male** and female), insomnia, nervousness,<br />

depression, abnormal dreams, anxiety, depersonalization<br />

Respiratory System: dyspnea, epistaxis<br />

Skin and Appendages: angioedema, erythema multiforme, pruritus,** rash,**<br />

rash erythem atous, rash maculopapular<br />

**These events occurred in less than 1% in placebo-controlled trials, but the<br />

incidence <strong>of</strong> these side effects was between 1% and 2% in all multiple dose studies.<br />

Special Senses: abnormal vision, conjunctivitis, diplopia, eye pain, tinnitus<br />

Urinary System: micturition frequency, micturition disorder, nocturia


Autonomic Nervous System: dry mouth, sweating increased<br />

Metabolic and Nutritional: hyperglycemia, thirst<br />

Hemopoietic: leukopenia, purpura, thrombocytopenia<br />

Other events reported with amlodipine at a frequency <strong>of</strong> ≤0.1% <strong>of</strong> patients<br />

include: cardiac failure, pulse irregularity, extrasystoles, skin discoloration,<br />

urticaria, skin dryness, alopecia, dermatitis, muscle weakness, twitching, ataxia,<br />

hypertonia, migraine, cold and clammy skin, apathy, agitation, amnesia, gastritis,<br />

increased appetite, loose stools, rhinitis, dysuria, polyuria, parosmia, taste<br />

perversion, abnormal visual accommodation, and xerophthalmia. Other reactions<br />

occurred sporadically and cannot be distinguished from medications or concurrent<br />

disease states such as myocardial infarction and angina.<br />

6.2 Clinical Laboratory Test Abnormalities<br />

RBC count, hemoglobin and hematocrit: Small mean changes from baseline<br />

were seen in RBC count, hemoglobin and hematocrit in patients treated with<br />

both Tekamlo and aliskiren monotherapy. This effect is also seen with other<br />

agents acting on the renin angiotensin system. In aliskiren monotherapy trials<br />

these decreases led to slight increases in rates <strong>of</strong> anemia compared to placebo<br />

(0.1% for any aliskiren use, 0.3% for aliskiren 600 mg daily, vs. 0% for<br />

placebo). No patients discontinued due to anemia.<br />

Blood Urea Nitrogen (BUN)/Creatinine: Elevations in BUN (>40 mg/dL) and creat -<br />

inine (>2.0 mg/dL) in patients treated with Tekamlo were 5.5 mEq/L were infrequent in<br />

patients with essential hypertension treated with both Tekamlo and aliskiren<br />

monotherapy (0.9% compared to 0.6% with placebo). However, when aliskiren<br />

was used in combination with an angiotensin-converting enzyme inhibitor (ACEI)<br />

in a diabetic population, increases in serum potassium were more frequent<br />

(5.5%). Monitor electrolytes and renal function in this population.<br />

6.3 Post-marketing Experience<br />

The following adverse reactions have been identified during postapproval use <strong>of</strong><br />

either aliskiren or amlodipine. Because these reactions are reported voluntarily<br />

from a population <strong>of</strong> uncertain size, it is not always possible to estimate their<br />

frequency or establish a causal relationship to drug exposure:<br />

Hypersensitivity: angioedema requiring airway management and hospitalization<br />

Aliskiren: Peripheral edema, blood creatinine increased<br />

Amlodipine: The following postmarketing event has been reported infrequently<br />

where a causal relationship is uncertain: gynecomastia. In postmarketing experience,<br />

jaundice and hepatic enzyme elevations (mostly consistent with cholestasis<br />

or hepatitis), in some cases severe enough to require hospitalization, have<br />

been reported in association with use <strong>of</strong> amlodipine.<br />

7 DRUG INTERACTIONS<br />

No drug interaction studies have been conducted with Tekamlo and other drugs,<br />

although studies with the individual aliskiren and amlodipine besylate components<br />

are described below.<br />

Aliskiren<br />

Cyclosporine: Avoid co-administration <strong>of</strong> cyclosporine with aliskiren.<br />

Itraconazole: Avoid co-administration <strong>of</strong> itraconazole with aliskiren.<br />

[See Clinical Pharmacology (12.3) in the full prescribing information.]<br />

Amlodipine besylate<br />

In clinical trials, amlodipine has been safely administered with thiazide diuretics,<br />

beta-blockers, angiotensin-converting enzyme inhibitors, long-acting nitrates,<br />

sublingual nitroglycerin, digoxin, warfarin, non-steroidal anti-inflammatory<br />

drugs, antibiotics, and oral hypoglycemic drugs.<br />

Cimetidine: Co-administration <strong>of</strong> amlodipine with cimetidine did not alter the<br />

pharmacokinetics <strong>of</strong> amlodipine.<br />

Grapefruit juice: Co-administration <strong>of</strong> 240 mL <strong>of</strong> grapefruit juice with a single<br />

oral dose <strong>of</strong> amlodipine 10 mg in 20 healthy volunteers had no significant effect<br />

on the pharmacokinetics <strong>of</strong> amlodipine.<br />

Maalox ® (antacid): Co-administration <strong>of</strong> the antacid Maalox with a single dose <strong>of</strong><br />

amlodipine had no significant effect on the pharmacokinetics <strong>of</strong> amlodipine.<br />

Sildenafil: A single 100 mg dose <strong>of</strong> sildenafil in subjects with essential hyper -<br />

tension had no effect on the pharmacokinetic parameters <strong>of</strong> amlodipine. When


amlodipine and sildenafil were used in combination, each agent independently<br />

exerted its own blood pressure lowering effect.<br />

Atorvastatin: Co-administration <strong>of</strong> multiple 10 mg doses <strong>of</strong> amlodipine with 80 mg<br />

<strong>of</strong> atorvastatin resulted in no significant change in the steady-state pharmaco -<br />

kinetic param eters <strong>of</strong> atorvastatin.<br />

Digoxin: Co-administration <strong>of</strong> amlodipine with digoxin did not change serum<br />

digoxin levels or digoxin renal clearance in normal volunteers.<br />

Ethanol (alcohol): Single and multiple 10 mg doses <strong>of</strong> amlodipine had no significant<br />

effect on the pharmacokinetics <strong>of</strong> ethanol.<br />

Warfarin: Co-administration <strong>of</strong> amlodipine with warfarin did not change the<br />

warfarin prothrombin response time.<br />

8 USE IN SPECIFIC POPULATIONS<br />

8.1 Pregnancy<br />

Pregnancy Category D [See Warnings and Precautions Section]<br />

The use <strong>of</strong> drugs that act directly on the renin-angiotensin-aldosterone system<br />

during the second and third trimesters <strong>of</strong> pregnancy can cause fetal and neo -<br />

natal morbidity and death. In addition, first trimester use <strong>of</strong> ACE inhibitors has<br />

been associated with birth defects in retrospective data. No animal studies were<br />

conducted with Tekamlo; however, decreased fetal birth weight was observed in<br />

animal studies with aliskiren and intrauterine deaths were observed in animal<br />

studies with amlodipine. Tekamlo can cause fetal harm when administered to a<br />

pregnant woman. When pregnancy is detected, discontinue Tekamlo as soon as<br />

possible. If Tekamlo is used during pregnancy, or if the patient becomes pregnant<br />

while taking this drug, the patient should be apprised <strong>of</strong> the potential hazard<br />

to the fetus.<br />

Human Data and Clinical Considerations<br />

Maternal hypertension is associated with increased risks for preterm delivery,<br />

intrauterine growth restriction, placental abruption, preeclampsia, and perinatal<br />

mortality. Appropriate management <strong>of</strong> maternal hypertension during pregnancy<br />

is important to optimize outcomes for both mother and fetus. Renin inhibitors<br />

(like aliskiren), angiotensin II receptor antagonists and angiotensin converting<br />

enzyme (ACE) inhibitors exert similar effects on the renin-angiotensin-aldosterone<br />

system. Based on several dozen published cases, ACE inhibitor use during the<br />

second and third trimesters <strong>of</strong> pregnancy is associated with fetal and neonatal<br />

injury, including hypotension, neonatal skull hypoplasia, anuria, reversible or<br />

irreversible renal failure, and death. Decreased fetal renal function may result in<br />

oligohydramnios and associated with fetal limb contractures, crani<strong>of</strong>acial deformation,<br />

and hypoplastic lung development. Prematurity, intrauterine growth<br />

retardation, and patent ductus arteriosus have been reported in women using<br />

these drugs, but it is not clear whether these occurrences were due to drug<br />

exposure. Limited data are conflicting about whether first trimester use <strong>of</strong> ACE<br />

inhibitors is associated with an increased risk <strong>of</strong> birth defects, but the drugs’<br />

mechanism <strong>of</strong> action raises a theoretical concern.<br />

When pregnancy occurs in a patient using Tekamlo, the physician should discontinue<br />

Tekamlo treatment as soon as possible. Inform the patient about potential<br />

risks to the fetus based on the time <strong>of</strong> gestational exposure to Tekamlo (first<br />

trimester only or later). If exposure occurs beyond the first trimester, perform an<br />

ultrasound examination.<br />

In rare cases when another antihypertensive agent cannot be used to treat the<br />

pregnant patient, serial ultrasound examinations should be used to assess the<br />

intraamniotic environment. Routine fetal testing with non-stress tests, biophysical<br />

pr<strong>of</strong>iles, and/or contraction stress tests may be appropriate based on gestational<br />

age and standards <strong>of</strong> care in the community. If oligohydramnios occurs in<br />

these situations, individualized decisions about continuing or discontinuing<br />

Tekamlo treatment and about pregnancy management should be made by the<br />

patient and her physicians. Patients and physicians should be aware that oligohydramnios<br />

may not appear until after the fetus has sustained irreversible injury.<br />

Infants exposed to Tekamlo in-utero should be closely observed for hypotension,<br />

oliguria, and hyperkalemia. If oliguria occurs, these infants may require blood<br />

pressure and renal perfusion support. Exchange transfusion or dialysis may be<br />

required to reverse hypotension and/or support decreased renal function.


Animal Data<br />

No reproductive toxicity studies have been conducted with the combination <strong>of</strong><br />

aliskiren and amlodipine besylate. However, these studies have been conducted<br />

for aliskiren and amlodipine besylate alone.<br />

Aliskiren<br />

In developmental toxicity studies, pregnant rats and rabbits received oral<br />

aliskiren hemifumarate during organogenesis at doses up to 20 and 7 times<br />

the maximum recommended human dose (MRHD) based on body surface<br />

area (mg/m 2 ), respectively, in rats and rabbits. (Actual animal doses were up<br />

to 600 mg/kg/day in rats and up to 100 mg/kg/day in rabbits.) No teratogenicity<br />

was observed; however, fetal birth weight was decreased in rabbits at<br />

doses 3.2 times the MRHD based on body surface area (mg/m 2 ). Aliskiren<br />

was present in placentas, amniotic fluid and fetuses <strong>of</strong> pregnant rabbits.<br />

Amlodipine<br />

In developmental toxicity studies, pregnant rats and rabbits received oral<br />

amlodipine maleate during organogenesis at doses approximately 10 and 20<br />

times the maximum recommended human dose (MRHD) based on body surface<br />

area (mg/m 2 ), respectively, in rats and rabbits. (Actual animal doses<br />

were up to 10 mg/kg/day.) No evidence <strong>of</strong> teratogenicity or other embryo fetal<br />

toxicity was observed. However, litter size was decreased approximately 50%<br />

and the num ber <strong>of</strong> intrauterine deaths was increased approximately 5-fold for<br />

rats receiving amlodipine maleate at doses approximately 10 times the MRHD<br />

based on body surface area (mg/m 2 ) for 14 days before mating and throughout<br />

mating and gestation. Amlodipine maleate has been shown to prolong<br />

both the gestation period and the duration <strong>of</strong> labor in rats at this dose.<br />

8.3 Nursing Mothers<br />

It is not known whether aliskiren or amlodipine is excreted in human milk.<br />

Both aliskiren and amlodipine are secreted in the milk <strong>of</strong> lactating rats.<br />

Because <strong>of</strong> the potential for serious adverse reactions in human milk-fed<br />

infants from Tekamlo, a decision should be made whether to discontinue<br />

nursing or discontinue Tekamlo, taking into account the importance <strong>of</strong> the<br />

drug to the mother.<br />

8.4 Pediatric Use<br />

Safety and effectiveness <strong>of</strong> Tekamlo in pediatric patients have not been<br />

established.<br />

8.5 Geriatric Use<br />

Tekamlo<br />

In the short-term controlled clinical trials <strong>of</strong> Tekamlo, 17% <strong>of</strong> patients treated<br />

with Tekamlo were ≥65 years. No overall differences in safety or effectiveness<br />

were observed between these subjects and younger subjects. Other reported<br />

clinical experience has not identified differences in responses between the<br />

elderly and younger patients, but greater sensitivity <strong>of</strong> some older individuals<br />

cannot be ruled out.<br />

Aliskiren<br />

Impact <strong>of</strong> aging on aliskiren pharmacokinetics has been assessed, when<br />

compared to young adults (18-40 years), aliskiren mean AUC and C max in<br />

elderly subjects (>65 years) are increased by 57% and 28%, respectively.<br />

However, differences in efficacy and safety between the elderly and younger<br />

populations were minor, indicating that differences in exposure due to age do<br />

not significantly alter the clinical effect <strong>of</strong> the drug. Therefore, no starting<br />

dose adjustment in geriatric population is required.<br />

Amlodipine<br />

Other reported clinical experience has not identified differences in responses<br />

between the elderly and younger patients. However, elderly patients have<br />

decreased clearance <strong>of</strong> amlodipine with a resulting increase <strong>of</strong> AUC <strong>of</strong> approx -<br />

imately 40-60%. In general dose selection for an elderly patient should be<br />

cautious, usually starting at the low end <strong>of</strong> the dosing range, reflecting the<br />

greater frequency <strong>of</strong> decreased hepatic, renal or cardiac function, and <strong>of</strong> concomitant<br />

disease or other drug therapy.<br />

10 OVERDOSAGE<br />

Aliskiren<br />

Limited data are available related to overdosage in humans. The most likely<br />

manifestation <strong>of</strong> overdosage would be hypotension. If symptomatic hypotension<br />

should occur, provide supportive treatment.


Amlodipine besylate<br />

Single oral doses <strong>of</strong> amlodipine maleate equivalent to 40 mg amlodipine/kg<br />

and 100 mg amlodipine/kg in mice and rats, respectively, caused deaths. Single<br />

oral amlodipine maleate doses equivalent to 4 or more mg amlodipine/kg<br />

or higher in dogs (11 or more times the maximum recommended human<br />

dose on a mg/m 2 basis) caused a marked peripheral vasodilation and<br />

hypotension.<br />

Overdosage might be expected to cause excessive peripheral vasodilation<br />

with marked hypotension and possibly a reflex tachycardia. In humans,<br />

experience with intentional overdosage <strong>of</strong> amlodipine is limited. Reports <strong>of</strong><br />

intentional overdosage include a patient who ingested 250 mg and was<br />

asymptomatic and was not hospitalized; another (120 mg) was hospitalized,<br />

underwent gastric lavage and remained normotensive; the third (105 mg) was<br />

hospitalized and had hypotension (90/50 mmHg) which normalized following<br />

plasma expansion. A case <strong>of</strong> accidental drug overdose has been documented<br />

in a 19-month-old male who ingested 30 mg amlodipine (about 2 mg/kg).<br />

During the emergency room presentation, vital signs were stable with no evidence<br />

<strong>of</strong> hypotension, but a heart rate <strong>of</strong> 180 bpm. Ipecac was administered<br />

3.5 hours after ingestion and on subsequent observation (overnight) no<br />

sequelae were noted.<br />

If massive overdose should occur, active cardiac and respiratory monitoring<br />

should be instituted. Frequent blood pressure measurements are essential.<br />

Should hypotension occur, cardiovascular support including elevation <strong>of</strong> the<br />

extremities and the judicious administration <strong>of</strong> fluids should be initiated. If<br />

hypotension remains unresponsive to these conservative mea sures, administration<br />

<strong>of</strong> vasopressors (such as phenylephrine) should be considered with<br />

attention to circulating volume and urine output. Intravenous calcium gluco -<br />

nate may help to reverse the effects <strong>of</strong> calcium entry blockade. As amlodipine<br />

is highly protein bound, hemodialysis is not likely to be <strong>of</strong> benefit.<br />

Distributed by:<br />

Novartis Pharmaceuticals Corporation<br />

East Hanover, New Jersey 07936<br />

T<strong>2011</strong>-52<br />

March <strong>2011</strong><br />

©Novartis


Get to know TEKAMLO<br />

at booth 1100<br />

Ask our sales representative how to<br />

obtain pr<strong>of</strong>essional samples.*<br />

150/5 mg 300/5 mg 300/10 mg<br />

150/10 mg dose not shown.<br />

*Samples are not available at booth 1100.<br />

Please see brief summary <strong>of</strong> Prescribing Information,<br />

including Boxed WARNING, on adjacent pages.<br />

Tekamlo<br />

(aliskiren and amlodipine) tablets<br />

150/5mg • 150/10mg • 300/5mg • 300/10mg<br />

Novartis Pharmaceuticals Corporation<br />

East Hanover, New Jersey 07936-1080<br />

© <strong>2011</strong> Novartis Printed in USA 4/11 TKT-1053803

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!