Diabetic Retinopathy & Medical Retina - aioseducation

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Diabetic Retinopathy and Medical Retina Free Papers RESULTS All the patients in the study group had a relatively good best corrected snellen’s visual acuity. 11(55%) of the patients had a BCVA of 6/18. 4 patients (20%) had a BCVA of 6/12. 3 patients (15%) had a BCVA of 6/9 and only 2 patients (10%) had BCVA of 6/24. At 12 weeks after resolution of CSR 19 patients (95%) had a BCVA of 6/6. 1 patient (5%) had a BCVA of 6/9. The log MAR visual acuity at presentation was 0.42±0.13. At 6 weeks it was 0.13±0.11 and at 12 weeks it was 0.01±0.04. The wave pattern consisted of the following components: 1) The first small negative N35 wave. 2) A positive P50 wave at approx 45-60 ms measured from the N35 trough to P50 peak. 3) A larger negative N95 wave at approx 90- 100 ms measured from the P50 peak to the trough of N95. EYE P50 P50 N95 N95 % age % age Normal CSR Normal CSR reduction in reduction in P50 N95 MEAN 3.38 2.47 5.72 4.27 26.69 % 25.63 % SD 0.90 0.86 1.85 1.66 – – RANGE 2.0-5.1 1.2-4.5 2.9-9.1 1.8-7.7 – – The mean P50 value in the normal eye was 3.38 μv (SD 0.9) compared to 2.47 μv (SD 0.86) in the affected eye reflecting a 26.69% reduction in the mean P50 value. The mean N95 value in the normal eye was 5.72 μv (SD 1.85) compared to 4.27 μv (SD 0.1.66) in the affected eye reflecting a 25.63% reduction in the mean N95 value. The study showed that both P50 and N95 waves were significantly reduced in the affected eye a.c.t normal eye ( P
70th AIOC Proceedings, Cochin 2012 • To know the functional status in CSR, Pattern ERG is an excellent diagnostic modality. REFERENCES 1. Arden, G. B., Vaegen, and Hogg, C.R. .Clinical and experimental evidence that the pattern electroretinogram (PERG) is generated in more proximal retinal layers than the focal electroretinogram (FERG). Ann. N. Y. Acad. Sci. 1982;388:214-26. 2. Holder, G. E. Recording the pattern electroretinogram with the Arden gold foil electrode. J. Electrophysiol. Technol. 1988;14:183-90. 3. Chuang, E.L., Sharp, D.M., Fitzke, F.W., Kemp, C.M., Holden, A.L.and Bird, A.C. Retinal dysfunction in central serous retinopathy. Eye 1987;1:120-5. 4. Yozo Miyake, Noriyasu Shiroyama, Ichiro Ota, and Masayuki Horiguchi. Local Macular Electroretinographic Responses in Idiopathic Central Serous Chorioretinopathy. Am J Ophthalmol 1988;106:546-50. Outcome of Proliferative Diabetic Retinopathy Surgery with Pre-operative Bevacizumab as an Adjuvant Dr. Mahesh G., Dr. Giridhar A., Dr. Thomas Tachil, Dr. Rameez Hussain The primary goal of any vitrectomy surgery for Proliferative diabetic retinopathy is to restore useful vision by restoring the anatomical integrity of the retina. This complex surgery also aims at stabilizing the neovascular process thereby producing a long term visual and anatomical outcome. To accomplish this goal, vitrectomy for Proliferative diabetic retinopathy involves removal of the vitreous scaffold, surface fibrovascular membranes, clearing of vitreous hemorrhage and taut posterior hyaloid, endophotocoagulation, attaching the retina and give tamponade to maintain the attachment. Tractional retinal detachment and non resolving vitreous hemorrhage are the most common indication for diabetic vitrectomy. 1 The major intraoperative complication of diabetic vitrectomy is hemorrhage into the vitreous cavity and iatrogenic breaks which can cause serious impact on the anatomical and visual outcome. The most common indication of re-operation is recurrent hemorrhage in the vitreous cavity. Interventions such as intra venous aminocaproic acid, layering of sodium hyaluronate on sites of peeling and removal of fibrovascular membranes, intra ocular injections of thrombin, etc. were tried to prevent complications from dispersed hemorrhage which didn’t yielded the desired results. Intra vitreal use of Bevacizumab which is a full length humanized monoclonal antibody to the vascular endothelial growth factor has been 886
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