Glimpses 2009-2010.pdf - LV Prasad Eye Institute

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Name of the Project A randomised double-masked active controlled phase 3 study of the efficacy, safety and tolerability of repeated doses of intravitreal VEGF trap-eye in subjects with neovascular age related macular degeneration (AMD) VEGF TRAP study The treatment of fungal corneal ulcer with Povidone - Iodine 1.25% ophthalmic solution. A comparative clinical trial Comparative, randomized, open trial on the anti-inflammatory efficacy of diclofenac released from an intra ocular lens versus administration of 0.1% diclofenac eye-drops in the prevention of post operative inflammatory manifestations after cataract surgery. – Ancillary study: 1 year follow-up of the safety A retrospective analysis of long-term outcome of primary angle closure glaucoma patients treated with peripheral iridotomy Micro current stimulation for retinitis pigmentosa 650 device pilot study A phase 2/3 randomised, controlled double-masked multi-center comparitive trial in parallel groups to compare the safety and efficacy of intravitreous injections of 0.3 mg pegaptanib sodium (Macugen) given as often as every 6 weeks for 2 years, to sham injections in subjects with Diabetic Macular Edema (DME) involving the center of the macula A multi-center, placebo-controlled, randomized, parallel group dose-ranging study to assess the efficacy and safety of LX201 for prevention of corneal allograft rejection episodes and graft failure following penetrating keratoplasty with LX201 implantation in subjects who are at increased immunological risk. A multi-center, placebo-controlled, randomized, parallel group dose-ranging study to assess the efficacy and safety of LX201 for prevention of corneal allograft rejection episodes and graft failure following penetrating keratoplasty with LX201 implantation in subjects who have experienced one or more rejection episodes following penetrating keratoplasty Protein Kinase C ß Inhibitor -- reduction in the occurrence of center-threatening diabetic macular edema. B7A-MC-MBDL Clinical research projects Project Investigators Dr Raja Narayanan Dr Prashant Garg Dr Savitri Sharma Dr Virender S Sangwan Supported by Bayer HealthCare, Germany University of California, Los Angeles, USA IOL Tech Carl Zeiss MediTec, France 2008-2011 Dr Sirisha Senthil Pfizer, USA 2009-2011 Dr Subhadra Jalali ScyFix, USA 2007-2010 Dr Subhadra Jalali Pfizer, USA 2006-2012 Dr Virender S Sangwan LUX Biosciences, USA 2008-2010 Dr Virender S Sangwan LUX Biosciences, USA 2008-2010 Dr Subhadra Jalali Eli Lily, India 2005-2010 Duration 2008 onwards (Hyderabad and Bhubaneswar campuses) 2006-2011 Posurdex study for DME Dr Ajit Babu Majji Allergan, USA 2006-2009 Posurdex study for RVO Dr Annie Mathai Allergan, USA 2006-2009 Posurdex study for intermediate uveitis Dr Virender S Sangwan Allergan, USA 2006-2009 LUMINATE uveitis study (LX211-01-UV) Dr Somasheila Murthy Dr Soumyava Basu LUX Biosciences, USA 2007-2009 (Hyderabad and Bhubaneswar campuses) LUMINATE uveitis study (LX211-02-UV) LUMINATE uveitis study (LX211-03-UV) A phase 3 safety and efficacy study of vitreosolve for ophthalmic intravitreal injection for inducing posterior vitreous detachment in retinopathy subjects Comparison of postoperative refractive outcomes after calculation of IOL power using the IOL master and ultrasound biometry A phase II prospective, randomised, multi-center, diabetic vascular edema dose ranging, comparator study evaluating the efficacy and safety of PF-04523655 versus laser therapy (DEGAS) A 6-day, phase 3, multicenter, randomised, double-masked, parallel study to compare the safety and efficacy of Gatifloxacin 0.5% ophthalmic solution BD with that of vehicle in the treatment of acute bacterial conjunctivitis A study of unilateral retinoblastoma with and without histopathologic high-risk features and the role of adjuvant chemotherapy – a groupwide phase III study A phase 3 prospective, randomized, double-masked, 12-week parallel group study evaluating the efficacy and safety of Latanoprost and Timolol in paediatric subjects with glaucoma Indian Council of Medical Research National Retinoblastoma Registry Dr Somasheila Murthy Dr Soumyava Basu Dr Somasheila Murthy Dr Soumyava Basu Dr Ajit Babu Majji Dr Taraprasad Das LUX Biosciences, USA LUX Biosciences, USA Vitreo Retinal Agencies, USA 2007-2009 (Hyderabad and Bhubaneswar campuses) 2007-2009 (Hyderabad and Bhubaneswar campuses) 2008-2010 (Hyderabad and Bhubaneswar campuses) Dr Sujata Das Hyderabad Eye Research Foundation, India 2009 onwards Dr Soumyava Basu Pfizer, USA 2009 onwards Dr Prashant Garg Allergan, USA 2008-2009 Dr Santosh G Honavar National Childhood Cancer Foundation, USA 2009-2011 Dr Anil K Mandal Pfizer, USA 2009 (3 months study) Dr Santosh G Honavar Dr P M Fairooz Indian Council of Medical Research, India 2009 onwards Excellence Equity Efficiency Page 40 F_Inside_Pgs.indd 40 9/2/2010 12:33:20 PM
Publications 1. Agarwal RV, Murthy S, Sangwan VS, Biswas J. Current approach in diagnosis and management of anterior uveitis. Ind J Ophthalmol 2010; 58: 11-9 2. Balla MMS, Vemuganti GK, Kannabiran C, Honavar SG, Murthy R. Phenotypic characterization of retinoblastoma for the presence of putative cancer stem-like cell markers by flow cytometry. Invest Ophthalmol Vis Sci 2009; 50: 1506-14 3. Basu S, Das T, Biswas G. Bilateral toxoplasma retinochoroiditis in a patient with chronic myeloid leukemia treated with imatinib mesylate. Ocular Immunol Inflamm 2010; 18: 64-5 4. Basu S. Hypertensive retinopathy. In Ready Reckoner in Ophthalmology ed by Ramamurthy D. AJR Medi Solutions, New Delhi, 2010; 407-8 5. Bharadwaj SR, Candy TR. Accommodative and vergence responses to conflicting blur and disparity stimuli during development. J Vis 2009; 9: 1-18 6. Bhatia K, Narayanan R. B scan ultrasonography to screen for retinal tears in acute symptomatic age-related posterior vitreous detachment. Ophthalmology 2009; 116: 2262-3 7. Chakrabarti S. Genetic variants of glaucoma. International Glaucoma Review 2009; 10: 114-5 8. Chakrabarti S. Novel myocilin mutations. International Glaucoma Review 2009; 10: 171 9. Chakrabarti S. WDR36 gene mutations. International Glaucoma Review 2009; 11: 2 10. Chakrabarti S. Clinical forms of glaucoma: LOXL1 polymorphism and pseudoexfoliation in Chinese. International Glaucoma Review 2009; 11: 3 11. Chalasani ML, Swarup G, Balasubramanian D. Optineurin and its mutants: molecules associated with some forms of glaucoma. Ophthalmic Research 2009; 42: 176-84 12. Chaurasia S, Muralidhar R, Garg P, Gopinathan U. Donor corneal button related endophthalmitis after keratoplasty. Clin Exp Ophthalmol 2010; 38: 75-6 13. Cowden JW, Garg P, Filipec M. A patient presents with corneal ulcer. What work up and treatment would you recommend In Curbside consultation in cornea and external disease: 49 clinical questions ed by Price F W; Thorofare, NJ, Slack, 2010 14. Das S, Honavar SG, Dhepe N, Naik MN. Maternal skin allograft for cicatricial ectropion in congenital icthyosis. Ophthal Plast Reconst Surg 2010; 26: 42-3 15. Das T, Pathengay A, Hussain N, Biswas J. Eales’ disease: Diagnosis and management. Eye 2010; 24: 472-82 16. Das T, Deshmukh HS, Mathai A, Reddy AK. Stenotrophomonas maltophilia endogenous endophthalmitis: clinical presentation, sensitivity spectrum and management. J Med Microbiol 2009; 58: 837-8 17. Das T, Padhi T, Sharma S. Endophthalmitis management in India a decade and after the endophthalmitis vitrectomy study. e Ophthalmology 2010 18. Das T. Gene therapy in ocular disorders. In Ready Reckoner in Ophthalmology ed by Ramamurthy D. AJR Medi Solutions, New Delhi, 2010; 443-5 19. D’Britto V, Tiwari S, Purohit V, Wadgaonkar PP, Bhoraskar SV, Bhonde RR, Prasad BLV. Composites of plasma treated poly (etherimide) films with gold nanoparticles and lysine through layer by layer assembly: a “friendly rough” surface for cell adhesion and proliferation for tissue engineering applications. J Materials Chem 2009; 19: 544-50 20. Garg P, Chaurasia S, Vaddavalli PK, Muralidhar R, Mittal V, Gopinathan U. Microbial keratitis after LASIK. J Refract Surg 2009; 26: 209-16 21. Garg P. Pathogenesis of pterygium: role of Eph receptors and ligand ephrins. Can J Ophthalmol 2009; 44: 138-40 22. Garg P. Investigative modalities in infectious keratitis. Ind J Ophthalmol 2009; 57: 159 23. Garudadri CS. Pseudo-gonio synechia: an artifact on twomirror gonioscopy. Ind J Ophthalmol 2010; 58: 59-60 24. Gokhale NS, Vemuganti GK. Diclofenac-induced acute corneal melt after collagen crosslinking for keratoconus. Cornea 2010; 29: 117-9 25. Gopinathan U, Sharma S, Garg P, Rao GN. Review of epidemiological features, microbiological diagnosis and treatment outcome of microbial keratitis: experience of over a decade. Ind J Ophthalmol 2009; 57: 273-9 26. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Using Rasch analysis to revisit the validity of the cataract TyPE spec instrument for measuring cataract surgery outcomes. J Cataract Refract Surg 2009; 35: 1509-17 27. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Visual activities questionnaire: assessment of subscale validity for cataract surgery outcomes. J Cataract Refract Surg 2009; 35: 1961-9 28. Gothwal VK, Pesudovs K, Wright T, McMonnies CW. McMonnies questionnaire: enhancing screening for dry eye syndrome using Rasch analysis. Invest Ophthal Vis Sci 2010; 51: 1401-7 29. Gothwal VK, Pesudovs K. Interactive, computer-based, selfreported, visual function questionnaire: the PalmPilot-VFQ. Eye 2009; 23: 1572-81 30. Gothwal VK, Wright TA, Lamoureux EL, Lundström M, Pesudovs K. Catquest questionnaire: re-validation in an Australian cataract population. Clin Exp Ophthalmol 2009; 37: 785-94 31. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Activities of daily vision scale: what do the subscales measure Invest Ophthalmol Vis Sci 2010; 51: 694-700 32. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Cataract symptom scale: clarifying measurement. Br J Ophthalmol 2009; 93: 1652-6 33. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Cataract symptom score: Rasch re-validation. Ophthalmic Epidemiol 2009; 16: 296-303 34. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Guttman scale analysis of the distance vision scale. Invest Ophthalmol Vis Sci 2009; 50: 4496-501 35. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Rasch analysis of the quality of life and vision function questionnaire. Optom Vis Sci 2009; 86: E836-E844 36. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Rasch analysis of the visual function and quality of life questionnaires. Optom Vis Sci 2009; 86: 1160-8 37. Gothwal VK, Wright TA, Lamoureux EL, Pesudovs K. Validity of the adaptation to age-related vision loss scale in an Australian cataract population. J Optom 2009; 2: 142-7 38. Gupta R, Vemuganti GK, Reddy VA, Honavar SG. Histopathologic risk factors in retinoblastoma in India. Arch Pathol Lab Med 2009; 133: 1210-4 LVPEI Faculty highlighted Excellence Equity Efficiency Page 41 F_Inside_Pgs.indd 41 9/2/2010 12:33:21 PM
Page 1 and 2: Glimpses, 2009 - 2010 A brief activ
Page 3 and 4: Competence and Compassion Matching
Page 5 and 6: L V Prasad Eye Institute Education
Page 7 and 8: ... and the Network grows In operat
Page 9 and 10: A snapshot of the key guests on the
Page 11 and 12: Honor roll, 2009-10 Mohd Javed Ali,
Page 13 and 14: Visakhapatnam also inaugurated a 24
Page 15 and 16: Ocular Oncology Centre at L V Prasa
Page 17 and 18: REHABILITATION Where hope rests Med
Page 19 and 20: ‘‘ Volunteering: a difference t
Page 21 and 22: Give the Gift of Sight RIEB observe
Page 23 and 24: COMMUNITY EYE HEALTH Reaching out
Page 25 and 26: Sharing the benefits Anjaneyulu, a
Page 27 and 28: By October 2009, the Vision Centre
Page 29 and 30: EDUCATION Sharpening the edge of ex
Page 31 and 32: Extending the frontiers of cornea s
Page 33 and 34: LVPEI’s wide network with institu
Page 35 and 36: THE PROF BRIEN HOLDEN EYE RESEARCH
Page 37 and 38: elsewhere indicates that there are
Page 39 and 40: the Herpes Simplex Virus-1 (HSV), V
Page 41: Basic Research Projects Name of the
Page 45 and 46: 77. Rath S, Honavar SG, Naik M, Ana
Page 47 and 48: G Pratibha Rao Pratibha Rao played
Page 49 and 50: Founders Mr L V Prasad, India Mrs P
Page 51 and 52: Mr Kranti Gupta, India Mr Vinit Kum
Page 53 and 54: National Adilabad Mr Nimma Rajula D
Page 55 and 56: 8/31/2010 11:18:18 AM

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